On the public citation graph
The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
0 signed · 318 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ijc.22751openalex-snapshot
Distinct pharmacological properties of second generation HDAC inhibitors with the benzamide or hydroxamate head group
inferredcites →https://doi.org/10.1002/jcb.20532openalex-snapshot
Prospects: Histone deacetylase inhibitors
inferredcites →https://doi.org/10.1002/jnr.21046openalex-snapshot
Striatal specificity of gene expression dysregulation in Huntington's disease
inferredcites →https://doi.org/10.1007/0-387-29362-0_23openalex-snapshot
limma: Linear Models for Microarray Data
inferredcites →https://doi.org/10.1007/bf02686117openalex-snapshot
Distribution of histone deacetylases 1–11 in the rat brain
inferredcites →https://doi.org/10.1007/s00018-003-3013-zopenalex-snapshot
Polyglutamine diseases: a transcription disorder?
inferredcites →https://doi.org/10.1016/0092-8674(93)90585-eopenalex-snapshot
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
inferredcites →https://doi.org/10.1016/j.cell.2005.10.030openalex-snapshot
In Vitro Analysis of Huntingtin-Mediated Transcriptional Repression Reveals Multiple Transcription Factor Targets
inferredcites →https://doi.org/10.1016/s0092-8674(00)81369-0openalex-snapshot
Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice
inferredcites →https://doi.org/10.1016/s0168-9525(03)00074-xopenalex-snapshot
Transcriptional abnormalities in Huntington disease
inferredcites →https://doi.org/10.1016/s0306-4522(02)00205-1openalex-snapshot
Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57Bl/6 mice: behavioural and histopathological characterisation
inferredcites →https://doi.org/10.1016/s0361-9230(03)00185-0openalex-snapshot
Standardization and statistical approaches to therapeutic trials in the R6/2 mouse
inferredcites →https://doi.org/10.1038/35099568openalex-snapshot
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
inferredcites →https://doi.org/10.1038/nchembio815openalex-snapshot
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia
inferredcites →https://doi.org/10.1073/pnas.0437870100openalex-snapshot
Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease
inferredcites →https://doi.org/10.1073/pnas.0606373103openalex-snapshot
ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease
inferredcites →https://doi.org/10.1074/jbc.m410210200openalex-snapshot
Neuroprotective Effects of Phenylbutyrate in the N171-82Q Transgenic Mouse Model of Huntington's Disease
inferredcites →https://doi.org/10.1093/hmg/9.9.1259openalex-snapshot
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
inferredcites →https://doi.org/10.1093/hmg/ddl013openalex-snapshot
Regional and cellular gene expression changes in human Huntington's disease brain
inferredcites →https://doi.org/10.1093/hmg/ddm064openalex-snapshot
Modulation of nucleosome dynamics in Huntington's disease
inferredcites →https://doi.org/10.1093/hmg/ddm078openalex-snapshot
Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models
inferredcites →https://doi.org/10.1093/hmg/ddm133openalex-snapshot
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage
inferredcites →https://doi.org/10.1097/01.wco.0000084223.82329.bbopenalex-snapshot
Experimental therapeutics in Huntington's disease
inferredcites →https://doi.org/10.1111/j.1471-4159.2005.03588.xopenalex-snapshot
Selective deficits in the expression of striatal‐enriched mRNAs in Huntington's disease
inferredcites →https://doi.org/10.1126/science.1072613openalex-snapshot
Sp1 and TAFII130 Transcriptional Activity Disrupted in Early Huntington's Disease
inferredcites →https://doi.org/10.1126/science.1073845openalex-snapshot
A Glutamine-Rich Trail Leads to Transcription Factors
inferredcites →https://doi.org/10.1128/mcb.22.5.1277-1287.2002openalex-snapshot
Interaction of Huntington Disease Protein with Transcriptional Activator Sp1
inferredcites →https://doi.org/10.1146/annurev.pharmtox.45.120403.095825openalex-snapshot
CLINICAL DEVELOPMENT OF HISTONE DEACETYLASE INHIBITORS AS ANTICANCER AGENTS
inferredcites →https://doi.org/10.1186/gb-2004-5-10-r80openalex-snapshot
Bioconductor: open software development for computational biology and bioinformatics
inferredcites →https://doi.org/10.1212/01.wnl.0000138434.68093.67openalex-snapshot
In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease
inferredcites →https://doi.org/10.1371/journal.pone.0001958openalex-snapshot
HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model
inferredcites →https://doi.org/10.1517/13543784.11.12.1695openalex-snapshot
Histone deacetylase inhibitors: from target to clinical trials
inferredcites →https://doi.org/10.1523/jneurosci.23-28-09418.2003openalex-snapshot
Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice
inferredcites →https://doi.org/10.1523/jneurosci.2599-04.2004openalex-snapshot
Chemotherapy for the Brain: The Antitumor Antibiotic Mithramycin Prolongs Survival in a Mouse Model of Huntington's Disease
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.5281/zenodo.886877openalex-extracted
Lysine (K)-Deacetylase Inhibitors: The Real Next Step To Neuropsychiatric And Neurodegenerative Disorders?
inferred← citeshttps://doi.org/10.1002/9781118349045.ch4openalex-snapshot
Chromatin at the Intersection of Disease and Therapy
inferred← citeshttps://doi.org/10.1002/acn3.147openalex-snapshot
The promise and perils of HDAC inhibitors in neurodegeneration
inferred← citeshttps://doi.org/10.1002/advs.202512942openalex-snapshot
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal +/− Mouse Model of DYT25 Dystonia
inferred← citeshttps://doi.org/10.1002/ana.22526openalex-snapshot
A gene expression phenotype in lymphocytes from friedreich ataxia patients
inferred← citeshttps://doi.org/10.1002/emmm.201000084openalex-snapshot
Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease
inferred← citeshttps://doi.org/10.1002/mco2.638openalex-snapshot
Cerebellum in Alzheimer's disease and other neurodegenerative diseases: an emerging research frontier
inferred← citeshttps://doi.org/10.1002/med.21425openalex-snapshot
Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts
inferred← citeshttps://doi.org/10.1002/pauz.201000363openalex-snapshot
Lesezeichen im Buch des Lebens. Epigenetik
inferred← citeshttps://doi.org/10.1002/prp2.1135openalex-snapshot
Dopaminergic cell protection and alleviation of neuropsychiatric disease symptoms by VMAT2 expression through the class I HDAC inhibitor TC‐H 106
inferred← citeshttps://doi.org/10.1002/prp2.70057openalex-snapshot
HDAC4 /5 Inhibitor, LMK ‐235 Improves Animal Voluntary Movement in MPTP ‐Induced Parkinson's Disease Model
inferred← citeshttps://doi.org/10.1007/7355_2010_10openalex-snapshot
The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach
inferred← citeshttps://doi.org/10.1007/7854_2013_250openalex-snapshot
Therapeutic Strategies for Huntington’s Disease
inferred← citeshttps://doi.org/10.1007/978-1-4471-6455-5_6openalex-snapshot
Huntington’s Disease: Molecular Pathogenesis and New Therapeutic Perspectives
inferred← citeshttps://doi.org/10.1007/978-1-4614-0653-2_14openalex-snapshot
Machado-Joseph Disease and other Rare Spinocerebellar Ataxias
inferred← citeshttps://doi.org/10.1007/978-1-4939-9465-6_9openalex-snapshot
Neuroprotection in Huntington Disease
inferred← citeshttps://doi.org/10.1007/978-1-61779-049-2_9openalex-snapshot
Neuroprotection in Huntington’s Disease
inferred← citeshttps://doi.org/10.1007/978-1-61779-328-8_32openalex-snapshot
Evaluation of Histone Deacetylase Inhibitors as Therapeutics for Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1007/978-3-030-23810-0_106openalex-snapshot
Novel Therapeutic Challenges in Cerebellar Diseases
inferred← citeshttps://doi.org/10.1007/978-3-031-15485-0_31openalex-snapshot
Maternal Obesity and Its Epigenetic Effects
inferred← citeshttps://doi.org/10.1007/978-3-642-17426-1_12openalex-snapshot
Histone Deacetylase Inhibitors: A Novel Therapeutic Approach for Cognitive Disorders
inferred← citeshttps://doi.org/10.1007/978-4-431-55763-0_23openalex-snapshot
Therapeutics for Polyglutamine Diseases Through Protein Degradation Pathway: Targeting the Nucleus
inferred← citeshttps://doi.org/10.1007/978-981-15-1761-7_18openalex-snapshot
Traditional Plant Compounds for the Treatment of Neuropsychiatric Disorders
inferred← citeshttps://doi.org/10.1007/978-981-95-6099-8_14openalex-snapshot
Therapeutic Potential of HDAC Inhibitors in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1007/s00018-013-1296-2openalex-snapshot
The role of genetics in the establishment and maintenance of the epigenome
inferred← citeshttps://doi.org/10.1007/s00702-010-0430-7openalex-snapshot
Neuroinflammation in Huntington’s disease
inferred← citeshttps://doi.org/10.1007/s10787-024-01477-0openalex-snapshot
Neuroinflammation and the role of epigenetic-based therapies for Huntington’s disease management: the new paradigm
inferred← citeshttps://doi.org/10.1007/s12035-009-8067-yopenalex-snapshot
Focal Nature of Neurological Disorders Necessitates Isotype-Selective Histone Deacetylase (HDAC) Inhibitors
inferred← citeshttps://doi.org/10.1007/s12035-012-8316-3openalex-snapshot
Mouse Models of Polyglutamine Diseases in Therapeutic Approaches: Review and Data Table. Part II
inferred← citeshttps://doi.org/10.1007/s12035-014-8715-8openalex-snapshot
Transcription, Epigenetics and Ameliorative Strategies in Huntington’s Disease: a Genome-Wide Perspective
inferred← citeshttps://doi.org/10.1007/s12035-014-9058-1openalex-snapshot
c-Fos Protects Neurons Through a Noncanonical Mechanism Involving HDAC3 Interaction: Identification of a 21-Amino Acid Fragment with Neuroprotective Activity
inferred← citeshttps://doi.org/10.1007/s12311-009-0144-2openalex-snapshot
Cellular and Molecular Pathways Triggering Neurodegeneration in the Spinocerebellar Ataxias
inferred← citeshttps://doi.org/10.1007/s13148-010-0012-4openalex-snapshot
Histone deacetylase (HDAC) inhibitors in recent clinical trials for cancer therapy
inferred← citeshttps://doi.org/10.1007/s13148-011-0025-7openalex-snapshot
Targeting Huntington’s disease through histone deacetylases
inferred← citeshttps://doi.org/10.1007/s13273-024-00441-xopenalex-snapshot
Molecular targets of histone deacetylase inhibitors in neurodegeneration and neuroprotection
inferred← citeshttps://doi.org/10.1007/s13311-012-0112-2openalex-snapshot
Huntington's Disease and the Striatal Medium Spiny Neuron: Cell-Autonomous and Non-Cell-Autonomous Mechanisms of Disease
inferred← citeshttps://doi.org/10.1007/s13311-012-0157-2openalex-snapshot
Scriptaid, a Novel Histone Deacetylase Inhibitor, Protects Against Traumatic Brain Injury via Modulation of PTEN and AKT Pathway
inferred← citeshttps://doi.org/10.1007/s13311-013-0195-4openalex-snapshot
Experimental Models for Identifying Modifiers of Polyglutamine-Induced Aggregation and Neurodegeneration
inferred← citeshttps://doi.org/10.1007/s13311-013-0206-5openalex-snapshot
Epigenetic Mechanisms of Neurodegeneration in Huntington's Disease
inferred← citeshttps://doi.org/10.1007/s13670-012-0025-2openalex-snapshot
Epigenetic Factors in Neurodegeneration
inferred← citeshttps://doi.org/10.1007/s13670-012-0027-0openalex-snapshot
Epigenetics-Based Therapeutics for Neurodegenerative Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-12-369497-3.10032-9openalex-snapshot
Mouse Models of Mental Illness and Neurological Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-374767-9.00030-5openalex-snapshot
Chromatin Remodeling
inferred← citeshttps://doi.org/10.1016/b978-0-12-374947-5.00041-9openalex-snapshot
Genetics of Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-381328-2.00015-8openalex-snapshot
Pathogenic Mechanisms in Huntington's Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-384878-9.00012-1openalex-snapshot
Genetic Mouse Models of Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-417114-5.00025-5openalex-snapshot
Histone Deacetylase Inhibitors and Psychiatric Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-12-801893-4.00002-xopenalex-snapshot
Mechanisms underlying neurodegeneration in Huntington disease: applications to novel disease-modifying therapies
inferred← citeshttps://doi.org/10.1016/b978-0-12-801899-6.00026-7openalex-snapshot
Chromatin Landscape and Epigenetic Signatures in Neurological Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-12-802206-1.00032-5openalex-snapshot
Epigenetics in Neuropathologies of the Basal Ganglia
inferred← citeshttps://doi.org/10.1016/b978-0-12-802208-5.00001-1openalex-snapshot
Basic Epigenetic Mechanisms and Phenomena
inferred← citeshttps://doi.org/10.1016/b978-0-12-803239-8.00003-xopenalex-snapshot
Histone Deacetylases as Therapeutic Targets in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-805420-8.00007-xopenalex-snapshot
The Role of Histone Deacetylase Inhibition in the Accumulation and Stability of Disease-Related Proteins
inferred← citeshttps://doi.org/10.1016/b978-0-12-813796-3.00004-3openalex-snapshot
Epigenetic mechanisms in Huntington's disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-816422-8.00013-1openalex-snapshot
Epigenetic treatment of neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/b978-0-12-823577-5.00016-7openalex-snapshot
Histone Deacetylase Inhibitors and Psychiatric Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-323-31071-0.00013-5openalex-snapshot
Huntington disease
inferred← citeshttps://doi.org/10.1016/bs.acc.2020.09.004openalex-snapshot
Histone deacetylase in neuropathology
inferred← citeshttps://doi.org/10.1016/j.ab.2010.01.010openalex-snapshot
Identification of phenylbutyrate-generated metabolites in Huntington disease patients using parallel liquid chromatography/electrochemical array/mass spectrometry and off-line tandem mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.bbadis.2015.10.026openalex-snapshot
Signal transduction and epigenetic mechanisms in the control of microglia activation during neuroinflammation
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2010.08.012openalex-snapshot
Tuning acetylation levels with HAT activators: Therapeutic strategy in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.bbi.2013.01.086openalex-snapshot
Epigenetic changes at gene promoters in response to immune activation in utero
inferred← citeshttps://doi.org/10.1016/j.biocel.2015.04.009openalex-snapshot
Epigenetic-based therapies in the preclinical and clinical treatment of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.03.085openalex-snapshot
Design and synthesis of novel hybrid benzamide–peptide histone deacetylase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.07.067openalex-snapshot
Set-up of a new series of HDAC inhibitors: the 5,11-dihydrodibenzo[b,e]azepin-6-ones as privileged structures
inferred← citeshttps://doi.org/10.1016/j.brainres.2012.01.038openalex-snapshot
Epigenetic programming of neurodegenerative diseases by an adverse environment
inferred← citeshttps://doi.org/10.1016/j.brainres.2015.07.030openalex-snapshot
Metabolism and epigenetics in the nervous system: Creating cellular fitness and resistance to neuronal death in neurological conditions via modulation of oxygen-, iron-, and 2-oxoglutarate-dependent dioxygenases
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2011.07.021openalex-snapshot
Gene expression and behaviour in mouse models of HD
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2011.10.001openalex-snapshot
Longitudinal analysis of gene expression and behaviour in the HdhQ150 mouse model of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2011.10.002openalex-snapshot
Comparative analysis of pathology and behavioural phenotypes in mouse models of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.ceb.2010.11.001openalex-snapshot
Modeling general proteostasis: proteome balance in health and disease
inferred← citeshttps://doi.org/10.1016/j.chembiol.2009.07.010openalex-snapshot
Chemical Probes Identify a Role for Histone Deacetylase 3 in Friedreich's Ataxia Gene Silencing
inferred← citeshttps://doi.org/10.1016/j.crmeth.2022.100297openalex-snapshot
Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington’s disease models
inferred← citeshttps://doi.org/10.1016/j.ddtec.2015.10.006openalex-snapshot
Profiling technologies for the identification and characterization of small-molecule histone deacetylase inhibitors
inferred← citeshttps://doi.org/10.1016/j.drudis.2014.02.014openalex-snapshot
The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy
inferred← citeshttps://doi.org/10.1016/j.drudis.2014.03.016openalex-snapshot
Transcriptional dysregulation in Huntington's disease: a failure of adaptive transcriptional homeostasis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.01.077openalex-snapshot
Histone deacetylase 3 inhibitors in learning and memory processes with special emphasis on benzamides
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.04.002openalex-snapshot
Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically
inferred← citeshttps://doi.org/10.1016/j.gene.2014.11.022openalex-snapshot
Huntington's disease: An update of therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.jbc.2025.108287openalex-snapshot
Pathogenic mechanism of abnormal expression of HDAC3 in ovulatory granulosa cells inducing oocyte maturation disorder and its application in IVM
inferred← citeshttps://doi.org/10.1016/j.jbi.2016.10.011openalex-snapshot
Identifying impact of software dependencies on replicability of biomedical workflows
inferred← citeshttps://doi.org/10.1016/j.jneumeth.2015.07.026openalex-snapshot
Using Drosophila models of Huntington's disease as a translatable tool
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.117278openalex-snapshot
Pharmacological intervention of histone deacetylase enzymes in the neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/j.mito.2019.03.004openalex-snapshot
Novel proteomic changes in brain mitochondria provide insights into mitochondrial dysfunction in mouse models of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.nbd.2010.02.003openalex-snapshot
The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.nbd.2010.10.019openalex-snapshot
HDAC inhibitor sodium butyrate reverses transcriptional downregulation and ameliorates ataxic symptoms in a transgenic mouse model of SCA3
inferred← citeshttps://doi.org/10.1016/j.nbd.2011.02.008openalex-snapshot
Gene expression profiling of R6/2 transgenic mice with different CAG repeat lengths reveals genes associated with disease onset and progression in Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.nbd.2011.02.016openalex-snapshot
Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model
inferred← citeshttps://doi.org/10.1016/j.nbd.2011.03.017openalex-snapshot
Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay
inferred← citeshttps://doi.org/10.1016/j.nbd.2011.07.001openalex-snapshot
What have we learned from gene expression profiles in Huntington's disease?
inferred← citeshttps://doi.org/10.1016/j.nbd.2012.01.016openalex-snapshot
Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.nbd.2016.02.004openalex-snapshot
Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes
inferred← citeshttps://doi.org/10.1016/j.nbd.2019.104569openalex-snapshot
Antibody-based therapies for Huntington’s disease: current status and future directions
inferred← citeshttps://doi.org/10.1016/j.nbd.2020.105092openalex-snapshot
Inconsistencies in histone acetylation patterns among different HD model systems and HD post-mortem brains
inferred← citeshttps://doi.org/10.1016/j.nbd.2020.105155openalex-snapshot
Epigenetic mechanisms underlying enhancer modulation of neuronal identity, neuronal activity and neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.nepig.2014.10.002openalex-snapshot
Histone deacetylases (HDACs) and brain function
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2017.02.017openalex-snapshot
Regenerative medicine in Huntington’s disease: Strengths and weaknesses of preclinical studies
inferred← citeshttps://doi.org/10.1016/j.neuint.2014.03.012openalex-snapshot
The interplay between microRNAs and histone deacetylases in neurological diseases
inferred← citeshttps://doi.org/10.1016/j.neuint.2019.104642openalex-snapshot
Epigenetic mechanisms of neurodegenerative diseases and acute brain injury
inferred← citeshttps://doi.org/10.1016/j.neuint.2021.105074openalex-snapshot
Epigenetic regulation in Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.neulet.2015.01.051openalex-snapshot
Molecular mechanisms of synaptic remodeling in alcoholism
inferred← citeshttps://doi.org/10.1016/j.neulet.2015.10.060openalex-snapshot
DNA methylation in Huntington’s disease: Implications for transgenerational effects
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2016.03.001openalex-snapshot
Suberoylanilide hydroxamic acid increases progranulin production in iPSC-derived cortical neurons of frontotemporal dementia patients
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2020.02.006openalex-snapshot
HDAC inhibition leads to age-dependent opposite regenerative effect upon PTEN deletion in rubrospinal axons after SCI
inferred← citeshttps://doi.org/10.1016/j.neuron.2010.12.035openalex-snapshot
Huntington's Disease: Can Mice Lead the Way to Treatment?
inferred← citeshttps://doi.org/10.1016/j.neuron.2011.02.029openalex-snapshot
Huntington's Disease: Can Mice Lead the Way to Treatment?
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2013.10.025openalex-snapshot
What's wrong with epigenetics in Huntington's disease?
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2012.11.040openalex-snapshot
Epigenetic regulation in neurodevelopment and neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.nrl.2014.02.004openalex-snapshot
Mecanismos epigenéticos en el desarrollo de la memoria y su implicación en algunas enfermedades neurológicas
inferred← citeshttps://doi.org/10.1016/j.nrleng.2014.02.011openalex-snapshot
Epigenetic mechanisms in the development of memory and their involvement in certain neurological diseases
inferred← citeshttps://doi.org/10.1016/j.pbb.2009.08.001openalex-snapshot
Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2016.07.001openalex-snapshot
Modulating epigenetic HAT activity for reinstating acetylation homeostasis: A promising therapeutic strategy for neurological disorders
inferred← citeshttps://doi.org/10.1016/j.phrs.2010.01.011openalex-snapshot
HDAC inhibitors and neurodegeneration: At the edge between protection and damage
inferred← citeshttps://doi.org/10.1016/j.phrs.2015.08.002openalex-snapshot
Transcriptional dysregulation in Huntington’s disease: The role of histone deacetylases
inferred← citeshttps://doi.org/10.1016/j.phrs.2018.04.014openalex-snapshot
Epigenetic modulation by small molecule compounds for neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2015.05.002openalex-snapshot
The epigenetics of aging and neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2016.09.002openalex-snapshot
Histone deacetylases inhibitors (HDACis) as novel therapeutic application in various clinical diseases
inferred← citeshttps://doi.org/10.1016/j.tibs.2009.06.010openalex-snapshot
Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells
inferred← citeshttps://doi.org/10.1016/j.tins.2009.06.002openalex-snapshot
Multiple roles of HDAC inhibition in neurodegenerative conditions
inferred← citeshttps://doi.org/10.1016/j.tips.2009.07.002openalex-snapshot
Sodium valproate: an old drug with new roles
inferred← citeshttps://doi.org/10.1016/j.tips.2010.09.003openalex-snapshot
Targeting the correct HDAC(s) to treat cognitive disorders
inferred← citeshttps://doi.org/10.1016/j.vascn.2012.08.001openalex-snapshot
Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders
inferred← citeshttps://doi.org/10.1016/j.ymgme.2024.108360openalex-snapshot
The Mendelian disorders of chromatin machinery: Harnessing metabolic pathways and therapies for treatment
inferred← citeshttps://doi.org/10.1016/s1474-4422(10)70245-3openalex-snapshot
Huntington's disease: from molecular pathogenesis to clinical treatment
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c00799openalex-snapshot
The Emerging Landscape of Small-Molecule Therapeutics for the Treatment of Huntington’s Disease
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c00226openalex-snapshot
The Zinc-Binding Group Effect: Lessons from Non-Hydroxamic Acid Vorinostat Analogs
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.8b00099openalex-snapshot
Design, Synthesis, and Blood–Brain Barrier Transport Study of Pyrilamine Derivatives as Histone Deacetylase Inhibitors
inferred← citeshttps://doi.org/10.1021/acsptsci.5c00402openalex-snapshot
A First-in-Class Chemical-Induced Proximity System Achieves Dose-Dependent Control of Tumor Protein P53 Gene Activation in Preclinical Models of Gastric Cancer
inferred← citeshttps://doi.org/10.1021/jm200388eopenalex-snapshot
Optimization of the in Vitro Cardiac Safety of Hydroxamate-Based Histone Deacetylase Inhibitors
inferred← citeshttps://doi.org/10.1021/pr500514ropenalex-snapshot
Quantitative Proteomic Analysis Identifies Targets and Pathways of a 2-Aminobenzamide HDAC Inhibitor in Friedreich’s Ataxia Patient iPSC-Derived Neural Stem Cells
inferred← citeshttps://doi.org/10.1038/nature08537openalex-snapshot
Neuroscience in the era of functional genomics and systems biology
inferred← citeshttps://doi.org/10.1038/npp.2015.93openalex-snapshot
Pharmacological Selectivity Within Class I Histone Deacetylases Predicts Effects on Synaptic Function and Memory Rescue
inferred← citeshttps://doi.org/10.1038/nrn3427openalex-snapshot
Histone acetylation: molecular mnemonics on the chromatin
inferred← citeshttps://doi.org/10.1038/s41392-022-01078-9openalex-snapshot
The role of histone modifications: from neurodevelopment to neurodiseases
inferred← citeshttps://doi.org/10.1038/s41467-017-00353-6openalex-snapshot
Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements
inferred← citeshttps://doi.org/10.1038/s41467-019-13671-8openalex-snapshot
HDAC3 maintains oocyte meiosis arrest by repressing amphiregulin expression before the LH surge
inferred← citeshttps://doi.org/10.1038/s41467-025-58496-wopenalex-snapshot
Tip60 HAT activators as therapeutic modulators for Alzheimer’s disease
inferred← citeshttps://doi.org/10.1038/s41598-017-05125-2openalex-snapshot
A selective inhibitor of histone deacetylase 3 prevents cognitive deficits and suppresses striatal CAG repeat expansions in Huntington’s disease mice
inferred← citeshttps://doi.org/10.1038/s41598-020-75035-3openalex-snapshot
Disruption of Tip60 HAT mediated neural histone acetylation homeostasis is an early common event in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1038/scibx.2009.1428openalex-snapshot
In the mood for HDAC inhibitors
inferred← citeshttps://doi.org/10.1038/tp.2011.61openalex-snapshot
Disease- and age-related changes in histone acetylation at gene promoters in psychiatric disorders
inferred← citeshttps://doi.org/10.1039/c4bm00068dopenalex-snapshot
Alteration of epigenetic program to recover memory and alleviate neurodegeneration: prospects of multi-target molecules
inferred← citeshttps://doi.org/10.1051/jbio/2017002openalex-snapshot
Régulations épigénétiques et plasticité cérébrale : vers de nouvelles thérapies dans les maladies neurodégénératives ?
inferred← citeshttps://doi.org/10.1073/pnas.1415195112openalex-snapshot
HDAC inhibition imparts beneficial transgenerational effects in Huntington's disease mice via altered DNA and histone methylation
inferred← citeshttps://doi.org/10.1073/pnas.1415589111openalex-snapshot
Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy
inferred← citeshttps://doi.org/10.1074/jbc.m112.404707openalex-snapshot
Histone Deacetylase Inhibitor (HDACi) Suberoylanilide Hydroxamic Acid (SAHA)-mediated Correction of α1-Antitrypsin Deficiency
inferred← citeshttps://doi.org/10.1074/jbc.m807045200openalex-snapshot
Pimelic Diphenylamide 106 Is a Slow, Tight-binding Inhibitor of Class I Histone Deacetylases
inferred← citeshttps://doi.org/10.1080/14756366.2021.1900160openalex-snapshot
Modulation of SETDB1 activity by APQ ameliorates heterochromatin condensation, motor function, and neuropathology in a Huntington’s disease mouse model
inferred← citeshttps://doi.org/10.1080/17501911.2024.2419357openalex-snapshot
The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery
inferred← citeshttps://doi.org/10.1093/hmg/ddq548openalex-snapshot
In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons
inferred← citeshttps://doi.org/10.1093/hmg/dds379openalex-snapshot
Selective histone deacetylase (HDAC) inhibition imparts beneficial effects in Huntington's disease mice: implications for the ubiquitin–proteasomal and autophagy systems
inferred← citeshttps://doi.org/10.1093/hmg/ddu081openalex-snapshot
The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1
inferred← citeshttps://doi.org/10.1093/hmg/ddu561openalex-snapshot
Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains
inferred← citeshttps://doi.org/10.1093/hmg/ddw040openalex-snapshot
Allelic series of Huntington's disease knock-in mice reveals expression discorrelates
inferred← citeshttps://doi.org/10.1093/hmg/ddx046openalex-snapshot
Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease
inferred← citeshttps://doi.org/10.1093/jnen/nly073openalex-snapshot
Histone Deacetylase Inhibitors: A Therapeutic Key in Neurological Disorders?
inferred← citeshttps://doi.org/10.1093/med/9780199929146.003.0016openalex-snapshot
Preclinical Experimental Therapeutics
inferred← citeshttps://doi.org/10.1096/fj.09-134700openalex-snapshot
Histone deacetylase inhibitor ITF2357 is neuroprotective, improves functional recovery, and induces glial apoptosis following experimental traumatic brain injury
inferred← citeshttps://doi.org/10.1097/01.nt.0000413860.03611.68openalex-snapshot
Injecting Ganglioside GM1: An Experimental Approach for Huntington Disease That Might Soon Be Ready for Human Trials
inferred← citeshttps://doi.org/10.1101/087114openalex-snapshot
Genome-scale transcriptional regulatory network models for the mouse and human striatum predict roles for SMAD3 and other transcription factors in Huntington’s disease
inferred← citeshttps://doi.org/10.1101/2020.10.13.337154openalex-snapshot
Selective inhibition of histone deacetylase 1 and 3 improves motor phenotype and alleviates transcriptional dysregulation in Huntington’s disease mice
inferred← citeshttps://doi.org/10.1109/escience.2015.71openalex-snapshot
Multidisciplinary Collaboration to Facilitate Hypotheses Generation in Huntington's Disease
inferred← citeshttps://doi.org/10.1111/j.1460-9568.2009.06787.xopenalex-snapshot
Epigenetic dysregulation in cognitive disorders
inferred← citeshttps://doi.org/10.1111/j.1471-4159.2010.07122.xopenalex-snapshot
Rescue of gene expression by modified REST decoy oligonucleotides in a cellular model of Huntington’s disease
inferred← citeshttps://doi.org/10.1111/j.1476-5381.2009.00526.xopenalex-snapshot
Pharmacology of epigenetics in brain disorders
inferred← citeshttps://doi.org/10.1111/j.1755-5949.2010.00184.xopenalex-snapshot
Targeting Histone Deacetylases for the Treatment of Huntington's Disease
inferred← citeshttps://doi.org/10.1111/j.1755-5949.2010.00203.xopenalex-snapshot
Histone Deacetylases and Mood Disorders: Epigenetic Programming in Gene‐Environment Interactions
inferred← citeshttps://doi.org/10.1111/jnc.14309openalex-snapshot
Complex neuroprotective and neurotoxic effects of histone deacetylases
inferred← citeshttps://doi.org/10.1124/jpet.110.173294openalex-snapshot
Chronic Suppression of Phosphodiesterase 10A Alters Striatal Expression of Genes Responsible for Neurotransmitter Synthesis, Neurotransmission, and Signaling Pathways Implicated in Huntington’s Disease
inferred← citeshttps://doi.org/10.1146/annurev.biochem.052308.114844openalex-snapshot
Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
inferred← citeshttps://doi.org/10.1152/physrev.00012.2010openalex-snapshot
Epigenetic Regulation of Gene Expression in Physiological and Pathological Brain Processes
inferred← citeshttps://doi.org/10.1152/physrev.00041.2009openalex-snapshot
Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease
inferred← citeshttps://doi.org/10.1155/2011/124256openalex-snapshot
Transforming Growth Factor-Beta Signaling in the Neural Stem Cell Niche: A Therapeutic Target for Huntington's Disease
inferred← citeshttps://doi.org/10.1172/jci45364openalex-snapshot
The importance of integrating basic and clinical research toward the development of new therapies for Huntington disease
inferred← citeshttps://doi.org/10.1172/jci60806openalex-snapshot
HDAC3 is essential for DNA replication in hematopoietic progenitor cells
inferred← citeshttps://doi.org/10.1172/jci79942openalex-snapshot
HDAC inhibitor–dependent transcriptome and memory reinstatement in cognitive decline models
inferred← citeshttps://doi.org/10.1177/1535370218761149openalex-snapshot
Proteomic analysis identifies NPTX1 and HIP1R as potential targets of histone deacetylase-3-mediated neurodegeneration
inferred← citeshttps://doi.org/10.1177/1535370220928278openalex-snapshot
Histone deacetylase-3: Friend and foe of the brain
inferred← citeshttps://doi.org/10.1186/1471-2377-12-47openalex-snapshot
Huntington's Disease and its therapeutic target genes: a global functional profile based on the HD Research Crossroads database
inferred← citeshttps://doi.org/10.1186/1750-1326-7-12openalex-snapshot
Improvement of neuropathology and transcriptional deficits in CAG 140 knock-in mice supports a beneficial effect of dietary curcumin in Huntington's disease
inferred← citeshttps://doi.org/10.1186/1750-1326-8-42openalex-snapshot
Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model
inferred← citeshttps://doi.org/10.1186/1755-8794-6-52openalex-snapshot
NeuroGeM, a knowledgebase of genetic modifiers in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1186/2041-1480-6-5openalex-snapshot
Nanopublications for exposing experimental data in the life-sciences: a Huntington’s Disease case study
inferred← citeshttps://doi.org/10.1186/s12864-015-2251-4openalex-snapshot
Similar striatal gene expression profiles in the striatum of the YAC128 and HdhQ150 mouse models of Huntington’s disease are not reflected in mutant Huntingtin inclusion prevalence
inferred← citeshttps://doi.org/10.1186/s12868-019-0546-0openalex-snapshot
The Bdnf and Npas4 genes are targets of HDAC3-mediated transcriptional repression
inferred← citeshttps://doi.org/10.1186/s12950-015-0074-3openalex-snapshot
RETRACTED ARTICLE: Valproic acid attenuates intercellular adhesion molecule-1 and E-selectin through a chemokine ligand 5 dependent mechanism and subarachnoid hemorrhage induced vasospasm in a rat model
inferred← citeshttps://doi.org/10.1186/s12977-017-0335-8openalex-snapshot
Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells
inferred← citeshttps://doi.org/10.1186/s13072-019-0313-6openalex-snapshot
Chromatin accessibility and transcription dynamics during in vitro astrocyte differentiation of Huntington’s Disease Monkey pluripotent stem cells
inferred← citeshttps://doi.org/10.1186/s13229-020-00387-6openalex-snapshot
High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons
inferred← citeshttps://doi.org/10.1186/s40478-019-0750-2openalex-snapshot
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model
inferred← citeshttps://doi.org/10.1242/dmm.001719openalex-snapshot
Epigenetic changes in childhood asthma
inferred← citeshttps://doi.org/10.12688/f1000research.9703.1openalex-snapshot
A putative role for genome-wide epigenetic regulatory mechanisms in Huntington’s disease: A computational assessment
inferred← citeshttps://doi.org/10.1371/currents.hd.ec3547da1c2a520ba959ee7bf8bdd202openalex-snapshot
Effects of the Pimelic Diphenylamide Histone Deacetylase Inhibitor HDACi 4b on the R6/2 and N171-82Q Mouse Models of Huntington’s Disease
inferred← citeshttps://doi.org/10.1371/currents.rrn1172openalex-snapshot
Evaluation of Histone Deacetylases as Drug Targets in Huntington’s Disease modelsStudy of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model.
inferred← citeshttps://doi.org/10.1371/journal.pbio.1001257openalex-snapshot
Histone Deacetylase Complexes Promote Trinucleotide Repeat Expansions
inferred← citeshttps://doi.org/10.1371/journal.pone.0005747openalex-snapshot
Genetic Knock-Down of HDAC7 Does Not Ameliorate Disease Pathogenesis in the R6/2 Mouse Model of Huntington's Disease
inferred← citeshttps://doi.org/10.1371/journal.pone.0022231openalex-snapshot
Decreased Striatal RGS2 Expression Is Neuroprotective in Huntington's Disease (HD) and Exemplifies a Compensatory Aspect of HD-Induced Gene Regulation
inferred← citeshttps://doi.org/10.1371/journal.pone.0023691openalex-snapshot
Genome-Wide Identification of Bcl11b Gene Targets Reveals Role in Brain-Derived Neurotrophic Factor Signaling
showing the first 200 of 284 · page through all 284
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.