On the public citation graph

A patent review of immunoproteasome inhibitors

https://doi.org/10.1080/13543776.2018.1484904

0 signed · 85 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.201308984openalex-snapshot

Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the α‐Ketoamide Electrophile as an Auspicious Reversible Lead Motif

inferredcites →https://doi.org/10.1002/anie.201600190openalex-snapshot

Nonpeptidic Selective Inhibitors of the Chymotrypsin‐Like (β5 i) Subunit of the Immunoproteasome

inferredcites →https://doi.org/10.1002/cbic.201700021openalex-snapshot

Structural Elucidation of a Nonpeptidic Inhibitor Specific for the Human Immunoproteasome

inferredcites →https://doi.org/10.1002/cmdc.201600384openalex-snapshot

Immunoproteasome β5i‐Selective Dipeptidomimetic Inhibitors

inferredcites →https://doi.org/10.1006/jmbi.2000.3683openalex-snapshot

An algorithm for the prediction of proteasomal cleavages

inferredcites →https://doi.org/10.1006/jsbi.1998.3958openalex-snapshot

26S Proteasome Structure Revealed by Three-dimensional Electron Microscopy

inferredcites →https://doi.org/10.1007/bf03033282openalex-snapshot

Enhaced induction of the immunoproteasome by interferon gamma in neurons expressing mutant huntingtin

inferredcites →https://doi.org/10.1007/s00384-009-0679-1openalex-snapshot

Expression of catalytic proteasome subunits in the gut of patients with Crohn’s disease

inferredcites →https://doi.org/10.1007/s10350-006-0796-7openalex-snapshot

Enhanced Intestinal Expression of the Proteasome Subunit Low Molecular Mass Polypeptide 2 in Patients with Inflammatory Bowel Disease

inferredcites →https://doi.org/10.1016/j.bbcan.2011.10.003openalex-snapshot

The 26S proteasome complex: An attractive target for cancer therapy

inferredcites →https://doi.org/10.1016/j.bbrc.2010.05.104openalex-snapshot

Studies on immunoproteasome in human liver. Part I: Absence in fetuses, presence in normal subjects, and increased levels in chronic active hepatitis and cirrhosis

inferredcites →https://doi.org/10.1016/j.bmc.2017.11.048openalex-snapshot

Immunoproteasome inhibition and bioactivity of thiasyrbactins

inferredcites →https://doi.org/10.1016/j.bmcl.2014.05.025openalex-snapshot

Selective immunoproteasome inhibitors with non-peptide scaffolds identified from structure-based virtual screening

inferredcites →https://doi.org/10.1016/j.cell.2011.12.030openalex-snapshot

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

inferredcites →https://doi.org/10.1016/j.expneurol.2005.08.027openalex-snapshot

Non-neuronal induction of immunoproteasome subunits in an ALS model: Possible mediation by cytokines

inferredcites →https://doi.org/10.1016/j.expneurol.2007.03.024openalex-snapshot

Assessing the role of immuno-proteasomes in a mouse model of familial ALS

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2004.12.004openalex-snapshot

Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains

inferredcites →https://doi.org/10.1016/j.str.2014.11.017openalex-snapshot

Crystal Structure of the Human 20S Proteasome in Complex with Carfilzomib

inferredcites →https://doi.org/10.1016/j.yjmcc.2010.02.007openalex-snapshot

Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice

inferredcites →https://doi.org/10.1016/s0021-9258(17)37345-3openalex-snapshot

Distinct 19 S and 20 S subcomplexes of the 26 S proteasome and their distribution in the nucleus and the cytoplasm.

inferredcites →https://doi.org/10.1016/s0960-894x(99)00612-5openalex-snapshot

Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: Insights into specificity and potency

inferredcites →https://doi.org/10.1016/s1097-2765(01)00407-5openalex-snapshot

Proteins Are Unfolded on the Surface of the ATPase Ring before Transport into the Proteasome

inferredcites →https://doi.org/10.1021/acsmedchemlett.6b00496openalex-snapshot

Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit

inferredcites →https://doi.org/10.1021/jm801329vopenalex-snapshot

Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)

inferredcites →https://doi.org/10.1021/ml400531dopenalex-snapshot

Oxathiazolones Selectively Inhibit the Human Immunoproteasome over the Constitutive Proteasome

inferredcites →https://doi.org/10.1034/j.1399-0039.2003.00020.xopenalex-snapshot

Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: β 2 ‐microglobulin inactivation in MSI‐positive tumors and LMP7/TAP2 downregulation in MSI‐negative tumors

inferredcites →https://doi.org/10.1038/bjc.2012.243openalex-snapshot

A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice

inferredcites →https://doi.org/10.1038/icb.2016.50openalex-snapshot

Emerging role of immunoproteasomes in pathophysiology

inferredcites →https://doi.org/10.1038/ni.2203openalex-snapshot

Mice completely lacking immunoproteasomes show major changes in antigen presentation

inferredcites →https://doi.org/10.1038/nm.1978openalex-snapshot

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

inferredcites →https://doi.org/10.1038/s41467-017-01760-5openalex-snapshot

Structure of human immunoproteasome with a reversible and noncompetitive inhibitor that selectively inhibits activated lymphocytes

inferredcites →https://doi.org/10.1042/bj3450001openalex-snapshot

The proteasome activator 11 S REG (PA28) and Class I antigen presentation

inferredcites →https://doi.org/10.1042/bst0350012openalex-snapshot

Functions of the proteasome: from protein degradation and immune surveillance to cancer therapy

inferredcites →https://doi.org/10.1073/pnas.0501711102openalex-snapshot

IFN-γ-induced immune adaptation of the proteasome system is an accelerated and transient response

inferredcites →https://doi.org/10.1073/pnas.1009778107openalex-snapshot

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

inferredcites →https://doi.org/10.1073/pnas.1618548114openalex-snapshot

Brief treatment with a highly selective immunoproteasome inhibitor promotes long-term cardiac allograft acceptance in mice

inferredcites →https://doi.org/10.1073/pnas.96.18.10403openalex-snapshot

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

inferredcites →https://doi.org/10.1080/00365520902998679openalex-snapshot

Down-regulation of HLA class I antigen-processing machinery components in esophageal squamous cell carcinomas: Association with disease progression

inferredcites →https://doi.org/10.1084/jem.193.11.1319openalex-snapshot

Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral Cd8+ T Cells at the Levels of T Cell Repertoire and Presentation of Viral Antigens

inferredcites →https://doi.org/10.1089/10915360152559594openalex-snapshot

Prognostic Significance of Immuno-Proteosome Subunit Expression in Patients with Renal-Cell Carcinoma: A Preliminary Study

inferredcites →https://doi.org/10.1093/brain/awt083openalex-snapshot

Reactive glia show increased immunoproteasome activity in Alzheimer’s disease

inferredcites →https://doi.org/10.1093/emboj/21.11.2636openalex-snapshot

Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes

inferredcites →https://doi.org/10.1111/ajt.14435openalex-snapshot

The immunoproteasome: An old player with a novel and emerging role in alloimmunity

inferredcites →https://doi.org/10.1126/science.aaf8993openalex-snapshot

The inhibition mechanism of human 20 S proteasomes enables next-generation inhibitor design

inferredcites →https://doi.org/10.1136/annrheumdis-2018-eular.1100openalex-snapshot

FRI0296 Kzr-616, a selective inhibitor of the immunoproteasome, blocks the disease progression in multiple models of systemic lupus erythematosus (SLE)

inferredcites →https://doi.org/10.1136/annrheumdis-2018-eular.3344openalex-snapshot

AB0509 Kzr-616, a selective inhibitor of the immunoproteasome, shows a promising safety and target inhibition profile in a phase i, double-blind, single (SAD) and multiple ascending dose (MAD) study in healthy volunteers

inferredcites →https://doi.org/10.1155/2015/541984openalex-snapshot

New Insights into the Function of the Immunoproteasome in Immune and Nonimmune Cells

inferredcites →https://doi.org/10.1158/0008-5472.can-04-1341openalex-snapshot

High Frequency of Functionally Active Melan-A–Specific T Cells in a Patient with Progressive Immunoproteasome-Deficient Melanoma

inferredcites →https://doi.org/10.1158/0008-5472.can-05-0506openalex-snapshot

Effects of PS-341 on the Activity and Composition of Proteasomes in Multiple Myeloma Cells

inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-2146openalex-snapshot

Defects in the Human Leukocyte Antigen Class I Antigen Processing Machinery in Head and Neck Squamous Cell Carcinoma: Association with Clinical Outcome

inferredcites →https://doi.org/10.1172/jci29832openalex-snapshot

Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection

inferredcites →https://doi.org/10.1182/blood-2008-07-171637openalex-snapshot

Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors

inferredcites →https://doi.org/10.1186/s40478-017-0453-5openalex-snapshot

Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer’s disease-like APPPS1 mice

inferredcites →https://doi.org/10.1371/journal.pone.0009287openalex-snapshot

Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population

inferredcites →https://doi.org/10.18632/oncotarget.14428openalex-snapshot

Blockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes

inferredcites →https://doi.org/10.2174/1381612811319220018openalex-snapshot

Inhibitors of the Immunoproteasome: Current Status and Future Directions

inferredcites →https://doi.org/10.2174/156800911794519725openalex-snapshot

Second Generation Proteasome Inhibitors: Carfilzomib and Immunoproteasome-Specific Inhibitors (IPSIs)

inferredcites →https://doi.org/10.2741/4027openalex-snapshot

Immune and non-immune functions of the immunoproteasome

inferredcites →https://doi.org/10.3109/10409238.2016.1172554openalex-snapshot

The Immunoproteasome in oxidative stress, aging, and disease

inferredcites →https://doi.org/10.3390/toxics3030294openalex-snapshot

An Overview of Bortezomib-Induced Neurotoxicity

inferredcites →https://doi.org/10.4049/jimmunol.0903182openalex-snapshot

Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome

inferredcites →https://doi.org/10.4049/jimmunol.169.6.3046openalex-snapshot

Regulation of Immunoproteasome Subunit Expression In Vivo Following Pathogenic Fungal Infection

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3365008openalex-extracted

CNS-penetrant LMP2 Inhibitors as Potential Therapies for Age-related Macular Degeneration

inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111646openalex-snapshot

Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases

inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113455openalex-snapshot

Discovery of selective fragment-sized immunoproteasome inhibitors

inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114252openalex-snapshot

Identification of N, C-capped di- and tripeptides as selective immunoproteasome inhibitors

inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115856openalex-snapshot

Non-peptidic immunoproteasome β5i-selective inhibitor as potential treatment for idiopathic pulmonary fibrosis: Virtual screening, hit evolution and lead identification

inferred← citeshttps://doi.org/10.1016/j.gendis.2025.101861openalex-snapshot

The role of immunoproteasome in diabetes and diabetes-related complications

inferred← citeshttps://doi.org/10.1016/j.pharmthera.2022.108329openalex-snapshot

Targeting immunoproteasome in neurodegeneration: A glance to the future

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c00416openalex-snapshot

LMP2 Inhibitors as a Potential Treatment for Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.1c00291openalex-snapshot

Macrocyclic Immunoproteasome Inhibitors as a Potential Therapy for Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.8b00819openalex-snapshot

Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors

inferred← citeshttps://doi.org/10.1042/bsr20212721openalex-snapshot

Syrbactin-class dual constitutive- and immuno-proteasome inhibitor TIR-199 impedes myeloma-mediated bone degeneration in vivo

inferred← citeshttps://doi.org/10.1080/14728214.2020.1787985openalex-snapshot

Clinical trials and novel therapeutics in dermatomyositis

inferred← citeshttps://doi.org/10.2147/dddt.s265793openalex-snapshot

Proteasome, a Promising Therapeutic Target for Multiple Diseases Beyond Cancer

inferred← citeshttps://doi.org/10.21873/anticanres.12895openalex-snapshot

Thiasyrbactins Induce Cell Death via Proteasome Inhibition in Multiple Myeloma Cells

inferred← citeshttps://doi.org/10.2478/acph-2023-0032openalex-snapshot

Design and synthesis of amino-substituted N -arylpiperidinyl-based inhibitors of the (immuno)proteasome

inferred← citeshttps://doi.org/10.3390/cancers13194852openalex-snapshot

At the Cutting Edge against Cancer: A Perspective on Immunoproteasome and Immune Checkpoints Modulation as a Potential Therapeutic Intervention

inferred← citeshttps://doi.org/10.3390/ijms20143379openalex-snapshot

Cellular Responses to Proteasome Inhibition: Molecular Mechanisms and Beyond

inferred← citeshttps://doi.org/10.3390/ijms21207608openalex-snapshot

Reduced Proteasome Activity and Enhanced Autophagy in Blood Cells of Psoriatic Patients

inferred← citeshttps://doi.org/10.3390/jof8040403openalex-snapshot

Evaluation of the Antifungal Activities of Photorhabdus akhurstii and Its Secondary Metabolites against Phytopathogenic Colletotrichum gloeosporioides

inferred← citeshttps://doi.org/10.3390/medicina62061122openalex-snapshot

ONX-0914 Alleviates Impaired Diabetic Wound Healing by Restoring Redox Homeostasis and Modulating Pro-Inflammatory Response

inferred← citeshttps://doi.org/10.3390/molecules25061305openalex-snapshot

Psoralen Derivatives as Inhibitors of Mycobacterium tuberculosis Proteasome

inferred← citeshttps://doi.org/10.3390/molecules26020356openalex-snapshot

Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors

inferred← citeshttps://doi.org/10.3390/molecules30030755openalex-snapshot

Recent Advances in the Development of Immunoproteasome Inhibitors as Anti-Cancer Agents: The Past 5 Years

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.