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Immune and non-immune functions of the immunoproteasome

https://doi.org/10.2741/4027
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/art.21782openalex-snapshot
Tissue‐specific up‐regulation of the proteasome subunit β5i (LMP7) in Sjögren's syndrome
inferredcites →https://doi.org/10.1002/j.1460-2075.1994.tb06625.xopenalex-snapshot
Displacement of housekeeping proteasome subunits by MHC‐encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.
inferredcites →https://doi.org/10.1006/abbi.2000.2036openalex-snapshot
Catalytic Activities of the 20 S Proteasome, a Multicatalytic Proteinase Complex
inferredcites →https://doi.org/10.1006/bbrc.2000.3676openalex-snapshot
Tissue Distribution of Constitutive Proteasomes, Immunoproteasomes, and PA28 in Rats
inferredcites →https://doi.org/10.1006/jmbi.2000.3959openalex-snapshot
Characterisation of the newly identified human Ump1 homologue POMP and analysis of LMP7(β5i) incorporation into 20 S proteasomes 1 1Edited by R. Huber
inferredcites →https://doi.org/10.1007/bf03033282openalex-snapshot
Enhaced induction of the immunoproteasome by interferon gamma in neurons expressing mutant huntingtin
inferredcites →https://doi.org/10.1007/s10350-006-0796-7openalex-snapshot
Enhanced Intestinal Expression of the Proteasome Subunit Low Molecular Mass Polypeptide 2 in Patients with Inflammatory Bowel Disease
inferredcites →https://doi.org/10.1007/s11523-010-0165-2openalex-snapshot
Therapeutically targeting the SUMOylation, Ubiquitination and Proteasome pathways as a novel anticancer strategy
inferredcites →https://doi.org/10.1016/0955-0674(95)80031-xopenalex-snapshot
Ubiquitin, proteasomes, and the regulation of intracellular protein degradation
inferredcites →https://doi.org/10.1016/1074-7613(94)90043-4openalex-snapshot
Altered peptidase and viral-specific T cell response in LMP2 mutant mice
inferredcites →https://doi.org/10.1016/j.abb.2003.10.010openalex-snapshot
Altered proteasome function and subunit composition in aged muscle
inferredcites →https://doi.org/10.1016/j.cell.2010.07.036openalex-snapshot
Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress
inferredcites →https://doi.org/10.1016/j.cell.2010.08.002openalex-snapshot
The Immunoproteasome Cleans up after Inflammation
inferredcites →https://doi.org/10.1016/j.chembiol.2007.03.008openalex-snapshot
LMP2-Specific Inhibitors: Chemical Genetic Tools for Proteasome Biology
inferredcites →https://doi.org/10.1016/j.coi.2003.11.004openalex-snapshot
Proteasome and peptidase function in MHC-class-I-mediated antigen presentation
inferredcites →https://doi.org/10.1016/j.expneurol.2005.08.027openalex-snapshot
Non-neuronal induction of immunoproteasome subunits in an ALS model: Possible mediation by cytokines
inferredcites →https://doi.org/10.1016/j.febslet.2005.04.012openalex-snapshot
IRF‐1 mediates upregulation of LMP7 by IFN‐γ and concerted expression of immunosubunits of the proteasome
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2005.10.052openalex-snapshot
Upregulation of immunoproteasomes by nitric oxide: Potential antioxidative mechanism in endothelial cells
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2004.12.004openalex-snapshot
Immunoproteasome and LMP2 polymorphism in aged and Alzheimer's disease brains
inferredcites →https://doi.org/10.1016/j.yjmcc.2010.02.007openalex-snapshot
Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice
inferredcites →https://doi.org/10.1016/s0002-9440(10)65321-7openalex-snapshot
Down-Regulation of HLA Class I Antigen-Processing Molecules in Malignant Melanoma
inferredcites →https://doi.org/10.1016/s0003-9861(02)00341-7openalex-snapshot
Immunoproteasome expression in a nonimmune tissue, the ocular lens
inferredcites →https://doi.org/10.1016/s0014-5793(03)00582-9openalex-snapshot
Role of the proteasome in protein oxidation and neural viability following low‐level oxidative stress
inferredcites →https://doi.org/10.1016/s0021-9258(18)41681-xopenalex-snapshot
Purification of an 11 S regulator of the multicatalytic protease.
inferredcites →https://doi.org/10.1016/s0092-8674(00)80942-3openalex-snapshot
Ump1p Is Required for Proper Maturation of the 20S Proteasome and Becomes Its Substrate upon Completion of the Assembly
inferredcites →https://doi.org/10.1016/s0167-4889(97)00152-3openalex-snapshot
Constitutive and interferon-γ-induced expression of the human proteasome subunit multicatalytic endopeptidase complex-like 11EMBL accession number for MECL1 cDNA: Y13640.1
inferredcites →https://doi.org/10.1016/s1074-7613(00)80163-6openalex-snapshot
Processing of Some Antigens by the Standard Proteasome but Not by the Immunoproteasome Results in Poor Presentation by Dendritic Cells
inferredcites →https://doi.org/10.1016/s1470-2045(11)70020-1openalex-snapshot
Bortezomib-induced peripheral neuropathy: facts and genes
inferredcites →https://doi.org/10.1016/s1535-6108(04)00120-5openalex-snapshot
The development of proteasome inhibitors as anticancer drugs
inferredcites →https://doi.org/10.1038/386463a0openalex-snapshot
Structure of 20S proteasome from yeast at 2.4Å resolution
inferredcites →https://doi.org/10.1038/nm.1978openalex-snapshot
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
inferredcites →https://doi.org/10.1042/0264-6021:3530291openalex-snapshot
γ-Interferon decreases the level of 26 S proteasomes and changes the pattern of phosphorylation
inferredcites →https://doi.org/10.1042/bj20100878openalex-snapshot
The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes
inferredcites →https://doi.org/10.1073/pnas.0404101101openalex-snapshot
Inhibition of apoptosis in acute promyelocytic leukemia cells leads to increases in levels of oxidized protein and LMP2 immunoproteasome
inferredcites →https://doi.org/10.1073/pnas.0501711102openalex-snapshot
IFN-γ-induced immune adaptation of the proteasome system is an accelerated and transient response
inferredcites →https://doi.org/10.1073/pnas.91.20.9213openalex-snapshot
Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.
inferredcites →https://doi.org/10.1073/pnas.94.17.8970openalex-snapshot
The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome
inferredcites →https://doi.org/10.1073/pnas.95.6.2727openalex-snapshot
The ubiquitin-proteasome pathway: The complexity and myriad functions of proteins death
inferredcites →https://doi.org/10.1074/jbc.271.29.17275openalex-snapshot
Proteasome Subunits X and Y Alter Peptidase Activities in Opposite Ways to the Interferon-γ-induced Subunits LMP2 and LMP7
inferredcites →https://doi.org/10.1074/jbc.273.26.16177openalex-snapshot
Different Requirements for Signal Transducer and Activator of Transcription 1α and Interferon Regulatory Factor 1 in the Regulation of Low Molecular Mass Polypeptide 2 and Transporter Associated with Antigen Processing 1 Gene Expression
inferredcites →https://doi.org/10.1074/jbc.m001742200openalex-snapshot
Novel Propeptide Function in 20 S Proteasome Assembly Influences β Subunit Composition
inferredcites →https://doi.org/10.1084/jem.182.6.1865openalex-snapshot
The cleavage preference of the proteasome governs the yield of antigenic peptides.
inferredcites →https://doi.org/10.1084/jem.187.1.97openalex-snapshot
Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits
inferredcites →https://doi.org/10.1084/jem.193.11.1319openalex-snapshot
Immunoproteasomes Shape Immunodominance Hierarchies of Antiviral Cd8+ T Cells at the Levels of T Cell Repertoire and Presentation of Viral Antigens
inferredcites →https://doi.org/10.1089/ars.2006.8.130openalex-snapshot
LMP2 Knock-Out Mice Have Reduced Proteasome Activities and Increased Levels of Oxidatively Damaged Proteins
inferredcites →https://doi.org/10.1089/ars.2007.1679openalex-snapshot
Ischemic Preconditioning: From Molecular Mechanisms to Therapeutic Opportunities
inferredcites →https://doi.org/10.1093/oxfordjournals.jbchem.a124327openalex-snapshot
Interferon-γ Induces Different Subunit Organizations and Functional Diversity of Proteasomes1
inferredcites →https://doi.org/10.1096/fj.04-2578fjeopenalex-snapshot
Altered proteasome structure, function, and oxidation in aged muscle
inferredcites →https://doi.org/10.1096/fj.08-105940openalex-snapshot
Ischemic preconditioning‐induced cardioprotection is lost in mice with immunoproteasome subunit low molecular mass polypeptide‐2 deficiency
inferredcites →https://doi.org/10.1111/j.1365-2141.2010.08491.xopenalex-snapshot
PR‐924, a selective inhibitor of the immunoproteasome subunit LMP‐7, blocks multiple myeloma cell growth both in vitro and in vivo
inferredcites →https://doi.org/10.1111/j.1471-4159.2008.05345.xopenalex-snapshot
Immunoproteasome responds to injury in the retina and brain
inferredcites →https://doi.org/10.1111/j.1471-4159.2008.05762.xopenalex-snapshot
Age‐related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects
inferredcites →https://doi.org/10.1126/science.292.5521.1552openalex-snapshot
Impairment of the Ubiquitin-Proteasome System by Protein Aggregation
inferredcites →https://doi.org/10.1126/science.8066463openalex-snapshot
MHC Class I Expression in Mice Lacking the Proteasome Subunit LMP-7
inferredcites →https://doi.org/10.1128/iai.01134-07openalex-snapshot
The Proteasome Immunosubunit Multicatalytic Endopeptidase Complex-Like 1 Is a T-Cell-Intrinsic Factor Influencing Homeostatic Expansion
inferredcites →https://doi.org/10.1136/gut.2009.203554openalex-snapshot
Targeting the proteasome: partial inhibition of the proteasome by bortezomib or deletion of the immunosubunit LMP7 attenuates experimental colitis
inferredcites →https://doi.org/10.1146/annurev.bi.65.070196.004101openalex-snapshot
STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES
inferredcites →https://doi.org/10.1146/annurev.pharmtox.45.120403.100037openalex-snapshot
PROTEASOME INHIBITION IN MULTIPLE MYELOMA: Therapeutic Implication
inferredcites →https://doi.org/10.1158/0008-5472.can-04-1341openalex-snapshot
High Frequency of Functionally Active Melan-A–Specific T Cells in a Patient with Progressive Immunoproteasome-Deficient Melanoma
inferredcites →https://doi.org/10.1158/0008-5472.can-05-0506openalex-snapshot
Effects of PS-341 on the Activity and Composition of Proteasomes in Multiple Myeloma Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-05-2394openalex-snapshot
Bortezomib Inhibits PKR-Like Endoplasmic Reticulum (ER) Kinase and Induces Apoptosis via ER Stress in Human Pancreatic Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-05-2872openalex-snapshot
Tumor Cell Lines Expressing the Proteasome Subunit Isoform LMP7E1 Exhibit Immunoproteasome Deficiency
inferredcites →https://doi.org/10.1158/0008-5472.can-08-2873openalex-snapshot
Preferential Cytotoxicity of Bortezomib toward Hypoxic Tumor Cells via Overactivation of Endoplasmic Reticulum Stress Pathways
inferredcites →https://doi.org/10.1161/atvbaha.109.189407openalex-snapshot
Cardiovascular Inflammation and Lesion Cell Apoptosis
inferredcites →https://doi.org/10.1172/jci28804openalex-snapshot
Proteasome-mediated degradation of IκBα and processing of p105 in Crohn disease and ulcerative colitis
inferredcites →https://doi.org/10.1172/jci29832openalex-snapshot
Virus-induced type I IFN stimulates generation of immunoproteasomes at the site of infection
inferredcites →https://doi.org/10.1182/blood-2006-03-013128openalex-snapshot
NPI-0052, a novel proteasome inhibitor, induces caspase-8 and ROS-dependent apoptosis alone and in combination with HDAC inhibitors in leukemia cells
inferredcites →https://doi.org/10.1182/blood-2007-04-083188openalex-snapshot
Immunoproteasome down-modulation enhances the ability of dendritic cells to stimulate antitumor immunity
inferredcites →https://doi.org/10.1182/blood-2008-07-171637openalex-snapshot
Targeted inhibition of the immunoproteasome is a potent strategy against models of multiple myeloma that overcomes resistance to conventional drugs and nonspecific proteasome inhibitors
inferredcites →https://doi.org/10.1182/blood-2008-08-174797openalex-snapshot
Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells
inferredcites →https://doi.org/10.1182/blood-2009-05-223677openalex-snapshot
Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome
inferredcites →https://doi.org/10.1182/blood.v114.22.612.612openalex-snapshot
PR-924, a Selective Inhibitor of the Immunoproteasome Subunit LMP-7 Blocks Multiple Myeloma Cell Growth Both in Vitro and In Vivo.
inferredcites →https://doi.org/10.1200/jco.2005.05.081openalex-snapshot
The Ubiquitin-Proteasome Pathway and Its Role in Cancer
inferredcites →https://doi.org/10.1253/circj.cj-09-0706openalex-snapshot
Inflammation in Atherosclerosis: Transition From Theory to Practice
inferredcites →https://doi.org/10.1371/journal.pone.0014646openalex-snapshot
A Dominant Role for the Immunoproteasome in CD8+ T Cell Responses to Murine Cytomegalovirus
inferredcites →https://doi.org/10.1385/ir:24:3:245openalex-snapshot
Functional Regulation of Immunoproteasomes and Transporter Associated with Antigen Processing
inferredcites →https://doi.org/10.1523/jneurosci.23-37-11653.2003openalex-snapshot
Neuronal Induction of the Immunoproteasome in Huntington's Disease
inferredcites →https://doi.org/10.2353/ajpath.2006.050865openalex-snapshot
Ongoing Coxsackievirus Myocarditis Is Associated with Increased Formation and Activity of Myocardial Immunoproteasomes
inferredcites →https://doi.org/10.2353/ajpath.2009.090033openalex-snapshot
Differential Interferon Responses Enhance Viral Epitope Generation by Myocardial Immunoproteasomes in Murine Enterovirus Myocarditis
inferredcites →https://doi.org/10.4049/jimmunol.0903003openalex-snapshot
Unexpected Role for the Immunoproteasome Subunit LMP2 in Antiviral Humoral and Innate Immune Responses
inferredcites →https://doi.org/10.4049/jimmunol.0903182openalex-snapshot
Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome
inferredcites →https://doi.org/10.4049/jimmunol.169.6.3046openalex-snapshot
Regulation of Immunoproteasome Subunit Expression In Vivo Following Pathogenic Fungal Infection
inferredcites →https://doi.org/10.4049/jimmunol.175.2.1153openalex-snapshot
Immunoproteasome-Deficient Mice Mount Largely Normal CD8+ T Cell Responses to Lymphocytic Choriomeningitis Virus Infection and DNA Vaccination
inferredcites →https://doi.org/10.4049/jimmunol.176.11.6665openalex-snapshot
An Altered T Cell Repertoire in MECL-1-Deficient Mice
inferredcites →https://doi.org/10.4049/jimmunol.176.7.4075openalex-snapshot
T Cells Lacking Immunoproteasome Subunits MECL-1 and LMP7 Hyperproliferate in Response to Polyclonal Mitogens
inferredcites →https://doi.org/10.4049/jimmunol.177.12.8393openalex-snapshot
Heat Shock Up-Regulates lmp2 and lmp7 and Enhances Presentation of Immunoproteasome-Dependent Epitopes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3993288openalex-extracted
Melatonin Inhibits Angiotensin II–Induced Atrial Fibrillation Through Preventing Degradation of Ang II Type I Receptor–Associated Protein (ATRAP)
inferred← citeshttps://doi.org/10.1002/1878-0261.13443openalex-snapshot
Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment
inferred← citeshttps://doi.org/10.1002/advs.202523902openalex-snapshot
Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion
inferred← citeshttps://doi.org/10.1002/cbic.201200307openalex-snapshot
Activity‐Based Near‐Infrared Fluorescent Probe for LMP7: A Chemical Proteomics Tool for the Immunoproteasome in Living Cells
inferred← citeshttps://doi.org/10.1002/path.5368openalex-snapshot
Immunoproteasome subunit β5i regulates diet‐induced atherosclerosis through altering MERTK‐mediated efferocytosis in Apoe knockout mice
inferred← citeshttps://doi.org/10.1007/978-1-0716-5190-2_17openalex-snapshot
Combined In Silico Approaches for Virtual Screening of Noncovalent Immunoproteasome Inhibitors for Multiple Myeloma Treatment
inferred← citeshttps://doi.org/10.1007/978-1-4614-5847-0_12openalex-snapshot
Proteasome Inhibition as a Novel Strategy for Cancer Treatment
inferred← citeshttps://doi.org/10.1007/978-1-4939-0928-5_13openalex-snapshot
Assessment of Cytokine-Modulated Proteasome Activity
inferred← citeshttps://doi.org/10.1007/978-3-319-31251-4_7openalex-snapshot
Protein Degradation in Cardiomyocytes: Target Proteins and Clinical Consequences
inferred← citeshttps://doi.org/10.1007/s00018-023-04867-9openalex-snapshot
The immunoproteasome subunit β2i ameliorates myocardial ischemia/reperfusion injury by regulating Parkin-Mfn1/2-mediated mitochondrial fusion
inferred← citeshttps://doi.org/10.1007/s00109-025-02587-0openalex-snapshot
4-Hydroxychalcone alleviated Angiotensin II-induced atrial fibrillation via immunoproteasome-IKK-NF-κB signaling pathway modulation
inferred← citeshttps://doi.org/10.1007/s10238-024-01353-9openalex-snapshot
Inclusion body myositis, viral infections, and TDP-43: a narrative review
inferred← citeshttps://doi.org/10.1007/s12013-013-9626-4openalex-snapshot
Activity-Based Imaging Probes of the Proteasome
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2024.741284openalex-snapshot
Strategy combining mammalian fats with supplementation of pungent spices in aquafeeds, to mitigate negative impacts of fish oil replacement in fish performance, fillet quality and hepatic condition of gilthead seabream (Sparus aurata)
inferred← citeshttps://doi.org/10.1016/j.bbi.2018.04.009openalex-snapshot
Inhibition of immunoproteasome promotes angiogenesis via enhancing hypoxia-inducible factor-1α abundance in rats following focal cerebral ischaemia
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.05.011openalex-snapshot
Knockout of immunoproteasome subunit β2i ameliorates cardiac fibrosis and inflammation in DOCA/Salt hypertensive mice
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.08.021openalex-snapshot
Transcriptome of porcine alveolar macrophages activated by interferon-gamma and lipopolysaccharide
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115146openalex-snapshot
Melatonin inhibits angiotensin II–induced atrial fibrillation through preventing degradation of Ang II Type I Receptor–Associated Protein (ATRAP)
inferred← citeshttps://doi.org/10.1016/j.biochi.2016.02.015openalex-snapshot
Modified siRNA effectively silence inducible immunoproteasome subunits in NSO cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118296openalex-snapshot
Proteasome-activating peptide 1 attenuates cardiac ischaemia/reperfusion-induced ferroptosis through the β5i-p53-SLC7A11 axis
inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.176011openalex-snapshot
TCH-165 attenuates cardiac ischaemia/reperfusion injury by balancing mitochondrial dynamics via increasing proteasome activity
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.02.011openalex-snapshot
Soluble receptor for advanced glycation end-products protects against ischemia/reperfusion-induced myocardial apoptosis via regulating the ubiquitin proteasome system
inferred← citeshttps://doi.org/10.1016/j.fsi.2013.07.040openalex-snapshot
Genomic structural characterization and transcriptional expression analysis of proteasome activator PA28α and PA28β subunits from Oplegnathus fasciatus
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.04.061openalex-snapshot
Genome and transcriptome analyses providing insight into the immune response of pearl oysters after allograft and xenograft transplantations
inferred← citeshttps://doi.org/10.1016/j.fsi.2026.111481openalex-snapshot
Functional characterization of EcPSMB10: Suppression of RGNNV replication via inhibiting autophagy in vitro
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.142146openalex-snapshot
Lentinan alleviates angiotensin II-induced myocardial remodeling through LMP7-SOCS3 signaling
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115418openalex-snapshot
Lentinan ameliorates angiotensin II-induced hypertension-associated intestinal barrier injury through inactivation of PSMB8-ATRAP signaling
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2020.108569openalex-snapshot
Resveratrol confers neuroprotection against high-fat diet in a mouse model of Alzheimer's disease via modulation of proteolytic mechanisms
inferred← citeshttps://doi.org/10.1016/j.jprot.2013.01.004openalex-snapshot
Protein oxidation in aging and the removal of oxidized proteins
inferred← citeshttps://doi.org/10.1016/j.jprot.2014.04.008openalex-snapshot
Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity
inferred← citeshttps://doi.org/10.1016/j.jstrokecerebrovasdis.2016.08.027openalex-snapshot
Plasma Immunoproteasome Predicts Early Hemorrhagic Transformation in Acute Ischemic Stroke Patients
inferred← citeshttps://doi.org/10.1016/j.mam.2012.09.001openalex-snapshot
Protein damage, repair and proteolysis
inferred← citeshttps://doi.org/10.1016/j.mce.2019.110451openalex-snapshot
Ubiquitin proteasome system (UPS) activation in the cardiac hypertrophy of hyperthyroidism
inferred← citeshttps://doi.org/10.1016/j.neuint.2012.02.009openalex-snapshot
Protein homeostasis and aging: Role of ubiquitin protein ligases
inferred← citeshttps://doi.org/10.1016/j.neulet.2018.05.022openalex-snapshot
Upregulation of PSMB8 and cathepsins in the human brains of dementia with Lewy bodies
inferred← citeshttps://doi.org/10.1016/j.redox.2018.02.022openalex-snapshot
The immunoproteasome subunit LMP10 mediates angiotensin II-induced retinopathy in mice
inferred← citeshttps://doi.org/10.1016/j.redox.2018.10.021openalex-snapshot
Resveratrol as a new inhibitor of immunoproteasome prevents PTEN degradation and attenuates cardiac hypertrophy after pressure overload
inferred← citeshttps://doi.org/10.1016/j.redox.2023.102706openalex-snapshot
MK-886 protects against cardiac ischaemia/reperfusion injury by activating proteasome-Keap1-NRF2 signalling
inferred← citeshttps://doi.org/10.1016/j.tox.2015.04.009openalex-snapshot
Gene expression profiling identifies the novel role of immunoproteasome in doxorubicin-induced cardiotoxicity
inferred← citeshttps://doi.org/10.1016/j.virol.2019.05.017openalex-snapshot
Host cell protein PSMB10 interacts with viral NS3 protein and inhibits the growth of classical swine fever virus
inferred← citeshttps://doi.org/10.1016/j.yexmp.2012.05.008openalex-snapshot
LMP2, a novel immunohistochemical marker to distinguish renal oncocytoma from the eosinophilic variant of chromophobe renal cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2014.12.007openalex-snapshot
Activation of the cardiac proteasome promotes angiotension II-induced hypertrophy by down-regulation of ATRAP
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2019.09.010openalex-snapshot
Genetic ablation and pharmacological inhibition of immunosubunit β5i attenuates cardiac remodeling in deoxycorticosterone-acetate (DOCA)-salt hypertensive mice
inferred← citeshttps://doi.org/10.1016/j.ymthe.2019.09.025openalex-snapshot
Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice
inferred← citeshttps://doi.org/10.1017/s1751731115000555openalex-snapshot
PGF2α levels in Day 8 blood plasma are increased by the presence of one or more embryos in the uterus
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.1c00604openalex-snapshot
Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i)
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c02079openalex-snapshot
Discovery of Novel 1-Phenylpiperidine Urea-Containing Derivatives Inhibiting β-Catenin/BCL9 Interaction and Exerting Antitumor Efficacy through the Activation of Antigen Presentation of cDC1 Cells
inferred← citeshttps://doi.org/10.1021/jm501344nopenalex-snapshot
Proteasome Inhibitors with Pyrazole Scaffolds from Structure-Based Virtual Screening
inferred← citeshttps://doi.org/10.1021/np300231fopenalex-snapshot
Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome
inferred← citeshttps://doi.org/10.1021/pr300845eopenalex-snapshot
Embryonic Sex Induces Differential Expression of Proteins in Bovine Uterine Fluid
inferred← citeshttps://doi.org/10.1038/cddis.2014.46openalex-snapshot
TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain
inferred← citeshttps://doi.org/10.1038/cddis.2014.586openalex-snapshot
Inhibition of immunoproteasome reduces infarction volume and attenuates inflammatory reaction in a rat model of ischemic stroke
inferred← citeshttps://doi.org/10.1038/icb.2016.50openalex-snapshot
Emerging role of immunoproteasomes in pathophysiology
inferred← citeshttps://doi.org/10.1038/s41374-018-0102-zopenalex-snapshot
Interferon-γ mediates the protective effects of soluble receptor for advanced glycation end-product in myocardial ischemia/reperfusion
inferred← citeshttps://doi.org/10.1038/s41419-024-07189-1openalex-snapshot
Psmb8 inhibits mitochondrial fission and alleviates myocardial ischaemia/reperfusion injury by targeting Drp1 degradation
inferred← citeshttps://doi.org/10.1038/s41598-021-99724-9openalex-snapshot
Pan-cancer analysis of the prognostic and immunological role of PSMB8
inferred← citeshttps://doi.org/10.1039/c2mb25125fopenalex-snapshot
Revisiting the role of the immunoproteasome in the activation of the canonical NF-κB pathway
inferred← citeshttps://doi.org/10.1039/c3mb70471hopenalex-snapshot
A FRET-based approach for identification of proteasome catalytic subunit composition
inferred← citeshttps://doi.org/10.1042/bj20120298openalex-snapshot
Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1
inferred← citeshttps://doi.org/10.1042/cs20230732openalex-snapshot
ONX0914 inhibition of immunoproteasome subunit LMP7 ameliorates diabetic cardiomyopathy via restraining endothelial–mesenchymal transition
inferred← citeshttps://doi.org/10.1080/01902148.2017.1377784openalex-snapshot
Exposure to cigarette smoke extract and lipopolysaccharide modifies cytoskeleton organization in bronchial epithelial cells
inferred← citeshttps://doi.org/10.1080/13543776.2018.1484904openalex-snapshot
A patent review of immunoproteasome inhibitors
inferred← citeshttps://doi.org/10.1080/15257770.2016.1184275openalex-snapshot
Silencing of Inducible Immunoproteasome Subunit Expression by Chemically Modified siRNA and shRNA
inferred← citeshttps://doi.org/10.1080/15548627.2025.2457925openalex-snapshot
Limiting cap-dependent translation increases 20S proteasomal degradation and protects the proteomic integrity in autophagy-deficient skeletal muscle
inferred← citeshttps://doi.org/10.1089/ars.2013.5823openalex-snapshot
Targeting the Ubiquitin-Proteasome System in Heart Disease: The Basis for New Therapeutic Strategies
inferred← citeshttps://doi.org/10.1089/ars.2016.6802openalex-snapshot
The Proteasome and Oxidative Stress in Alzheimer's Disease
inferred← citeshttps://doi.org/10.1093/hmg/ddae013openalex-snapshot
Excessive tubulin glutamylation leads to progressive cone-rod dystrophy and loss of outer segment integrity
inferred← citeshttps://doi.org/10.1093/hmg/ddt338openalex-snapshot
Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors
inferred← citeshttps://doi.org/10.1093/jbcr/iry011openalex-snapshot
Immunoproteasome in the Plasma of Pediatric Patients With Moderate and Major Burns, and Its Correlation With Proteasome and UCHL1 Measured by SPR Imaging Biosensors
inferred← citeshttps://doi.org/10.1093/jimmun/vkae063openalex-snapshot
Virulent African swine fever virus infection of porcine monocytes causes SLA I subversion due to loss of proper ER structure/function
inferred← citeshttps://doi.org/10.1101/2022.08.30.505767openalex-snapshot
Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment
inferred← citeshttps://doi.org/10.1101/cshperspect.a013383openalex-snapshot
Expanding Proteostasis by Membrane Trafficking Networks
inferred← citeshttps://doi.org/10.1111/dom.13387openalex-snapshot
Islet stress, degradation and autoimmunity
inferred← citeshttps://doi.org/10.1111/jcmm.17104openalex-snapshot
Immunoproteasome modulates NLRP3 inflammasome‐mediated neuroinflammation under cerebral ischaemia and reperfusion conditions
inferred← citeshttps://doi.org/10.1111/jebm.12406openalex-snapshot
Phenotype variability of autoinflammatory disorders in the pediatric patient: A pictorial overview
inferred← citeshttps://doi.org/10.1111/jfd.70133openalex-snapshot
EcPSMB8 Contributes to Antiviral Immunity in Grouper by Modulating MHC I Signalling and Virus‐Induced Autophagy
inferred← citeshttps://doi.org/10.1111/jth.14730openalex-snapshot
Structure and function of the ubiquitin‐proteasome system in platelets
inferred← citeshttps://doi.org/10.1111/trf.16605openalex-snapshot
The platelet proteasome and immunoproteasome are stable in buffy‐coat derived platelet concentrates for up to 7 days
inferred← citeshttps://doi.org/10.1126/sciadv.aau0495openalex-snapshot
The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation
inferred← citeshttps://doi.org/10.1128/mcb.00622-13openalex-snapshot
Identification of the Immunoproteasome as a Novel Regulator of Skeletal Muscle Differentiation
inferred← citeshttps://doi.org/10.1128/mmbr.00177-25openalex-snapshot
Cellular protein quality control in viral myocarditis: molecular mechanisms and therapeutic implication
inferred← citeshttps://doi.org/10.1136/rmdopen-2022-002818openalex-snapshot
Immunoproteasome subunit β5i promotes perifascicular muscle atrophy in dermatomyositis by upregulating RIG-I
inferred← citeshttps://doi.org/10.1139/apnm-2020-0655openalex-snapshot
Obesity-induced alterations to the immunoproteasome: a potential link to intramuscular lipotoxicity
inferred← citeshttps://doi.org/10.1155/2021/6426225openalex-snapshot
Inhibition of the Immunoproteasome Subunit LMP7 Ameliorates Cerebral White Matter Demyelination Possibly via TGFβ/Smad Signaling
inferred← citeshttps://doi.org/10.1158/0008-5472.can-15-3125openalex-snapshot
BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-13-0156openalex-snapshot
In Vitro and In Vivo Therapeutic Efficacy of Carfilzomib in Mantle Cell Lymphoma: Targeting the Immunoproteasome
inferred← citeshttps://doi.org/10.1159/000487562openalex-snapshot
Angiotensin II Regulates Th1 T Cell Differentiation Through Angiotensin II Type 1 Receptor-PKA-Mediated Activation of Proteasome
inferred← citeshttps://doi.org/10.1161/hypertensionaha.117.10390openalex-snapshot
Novel Role for the Immunoproteasome Subunit PSMB10 in Angiotensin II–Induced Atrial Fibrillation in Mice
inferred← citeshttps://doi.org/10.1161/hypertensionaha.118.11813openalex-snapshot
Immunoproteasome Subunit β5i Promotes Ang II (Angiotensin II)–Induced Atrial Fibrillation by Targeting ATRAP (Ang II Type I Receptor–Associated Protein) Degradation in Mice
inferred← citeshttps://doi.org/10.1172/jci.insight.156914openalex-snapshot
Embryonic alcohol exposure disrupts the ubiquitin-proteasome system
inferred← citeshttps://doi.org/10.1172/jci146832openalex-snapshot
Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation
inferred← citeshttps://doi.org/10.1186/s12967-023-04071-0openalex-snapshot
LMP2 deficiency causes abnormal metabolism, oxidative stress, neuroinflammation, myelin loss and neurobehavioral dysfunctions
inferred← citeshttps://doi.org/10.1186/s12974-026-03709-2openalex-snapshot
The immunoproteasome as a neuroimmune hub in the central nervous system: from proteostasis stress to inflammatory pathology
inferred← citeshttps://doi.org/10.1186/s40779-021-00356-xopenalex-snapshot
Inhibition of the immunoproteasome LMP2 ameliorates ischemia/hypoxia-induced blood–brain barrier injury through the Wnt/β-catenin signalling pathway
inferred← citeshttps://doi.org/10.12659/msm.923621openalex-snapshot
Induction and Regulation of the Immunoproteasome Subunit β5i (PSMB8) in Laryngeal and Hypopharyngeal Carcinoma Cells
inferred← citeshttps://doi.org/10.1292/jvms.19-0157openalex-snapshot
Induction of immunoproteasomes in porcine kidney (PK)-15 cells by interferon-γ and tumor necrosis factor-α
inferred← citeshttps://doi.org/10.1371/journal.pone.0074506openalex-snapshot
The VHSE-Based Prediction of Proteasomal Cleavage Sites
inferred← citeshttps://doi.org/10.1371/journal.pone.0323013openalex-snapshot
Multifaceted investigations of PSMB8 provides insights into prognostic prediction and immunological target in thyroid carcinoma
inferred← citeshttps://doi.org/10.1371/journal.pone.0332881openalex-snapshot
Single cell RNA sequencing analysis and molecular biology experiments identify NAFLD-related fibroblasts and highlights seven hub genes in NAFLD
inferred← citeshttps://doi.org/10.1517/14728222.2013.815728openalex-snapshot
Targeting the ubiquitin–proteasome system for cancer therapy
inferred← citeshttps://doi.org/10.21037/jtd.2016.08.80openalex-snapshot
Immunoproteasome deficiency in non-small cell lung cancer and its relevance to immunotherapy
inferred← citeshttps://doi.org/10.2174/1381612811319180013openalex-snapshot
The Ubiquitin Proteasome System as a Potential Target for the Treatment of Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.2174/1381612811319220018openalex-snapshot
Inhibitors of the Immunoproteasome: Current Status and Future Directions
inferred← citeshttps://doi.org/10.2174/1568009614666140804154511openalex-snapshot
Overview of Proteasome Inhibitor-Based Anti-cancer Therapies: Perspective on Bortezomib and Second Generation Proteasome Inhibitors versus Future Generation Inhibitors of Ubiquitin-Proteasome System
inferred← citeshttps://doi.org/10.26512/2017.03.t.23393openalex-snapshot
Composição proteica e caracterização funcional da secreção cutânea de Dendropsophus columbianus (Boettger, 1892)
inferred← citeshttps://doi.org/10.3109/10409238.2016.1172554openalex-snapshot
The Immunoproteasome in oxidative stress, aging, and disease
inferred← citeshttps://doi.org/10.3109/10715762.2013.792926openalex-snapshot
Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
inferred← citeshttps://doi.org/10.32607/20758251-2016-8-3-17-30openalex-snapshot
Molecular and Cellular Mechanisms of Antitumor Immune Response Activation by Dendritic Cells
inferred← citeshttps://doi.org/10.3389/fcell.2020.592048openalex-snapshot
Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice
inferred← citeshttps://doi.org/10.3389/fcell.2020.594683openalex-snapshot
Gallic Acid Ameliorates Angiotensin II-Induced Atrial Fibrillation by Inhibiting Immunoproteasome- Mediated PTEN Degradation in Mice
inferred← citeshttps://doi.org/10.3389/fcell.2023.1124907openalex-snapshot
The proteasome: A key modulator of nervous system function, brain aging, and neurodegenerative disease
inferred← citeshttps://doi.org/10.3389/fimmu.2019.02756openalex-snapshot
Contribution of the Unfolded Protein Response (UPR) to the Pathogenesis of Proteasome-Associated Autoinflammatory Syndromes (PRAAS)
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1603816openalex-snapshot
From oncogenesis to prognosis: the roles of the immunoproteasome in cancer
inferred← citeshttps://doi.org/10.3389/fmolb.2024.1148948openalex-snapshot
Genetic ablation of Lmp2 increases the susceptibility for impaired cardiac function
inferred← citeshttps://doi.org/10.3389/fphar.2020.00885openalex-snapshot
Selective Inhibition of the Immunoproteasome β5i Prevents PTEN Degradation and Attenuates Cardiac Hypertrophy
inferred← citeshttps://doi.org/10.3389/fphar.2020.01121openalex-snapshot
Gallic Acid Attenuates Angiotensin II-Induced Hypertension and Vascular Dysfunction by Inhibiting the Degradation of Endothelial Nitric Oxide Synthase
inferred← citeshttps://doi.org/10.3389/fphys.2020.00625openalex-snapshot
Deficiency of the Immunoproteasome LMP10 Subunit Attenuates Angiotensin II-Induced Cardiac Hypertrophic Remodeling via Autophagic Degradation of gp130 and IGF1R
inferred← citeshttps://doi.org/10.3390/biom15111524openalex-snapshot
Cleaving Expectations: A Review of Proteasome Functional and Catalytic Diversity
inferred← citeshttps://doi.org/10.3390/biom6040043openalex-snapshot
Chronic Binge Alcohol Administration Dysregulates Hippocampal Genes Involved in Immunity and Neurogenesis in Simian Immunodeficiency Virus-Infected Macaques
inferred← citeshttps://doi.org/10.3390/cancers14205007openalex-snapshot
The Expression of the Immunoproteasome Subunit PSMB9 Is Related to Distinct Molecular Subtypes of Uterine Leiomyosarcoma
inferred← citeshttps://doi.org/10.3390/cells10123360openalex-snapshot
The Function of Immunoproteasomes—An Immunologists’ Perspective
inferred← citeshttps://doi.org/10.3390/cimb48010046openalex-snapshot
Targeting the Ubiquitin–Proteasome System in Atrial Fibrillation: Mechanistic Insights and Translational Perspectives
inferred← citeshttps://doi.org/10.3390/ijms232213771openalex-snapshot
A Novel Mechanism of Immunoproteasome Regulation via miR-369-3p in Intestinal Inflammatory Response
inferred← citeshttps://doi.org/10.3390/ijms24065924openalex-snapshot
Metabolite and Proteomic Profiling of Serum Reveals the Differences in Molecular Immunity between Min and Large White Pig Breeds
inferred← citeshttps://doi.org/10.3390/ijms241310732openalex-snapshot
Blunting Neuroinflammation by Targeting the Immunoproteasome with Novel Amide Derivatives
inferred← citeshttps://doi.org/10.3390/nu15041049openalex-snapshot
Ursolic Acid Ameliorates Myocardial Ischaemia/Reperfusion Injury by Improving Mitochondrial Function via Immunoproteasome-PP2A-AMPK Signalling
inferred← citeshttps://doi.org/10.33915/etd.12301openalex-snapshot
The function of protein glutamylation in vision
inferred← citeshttps://doi.org/10.4103/0366-6999.180513openalex-snapshot
Association Analysis of Proteasome Subunits and Transporter Associated with Antigen Processing on Chinese Patients with Parkinson's Disease
inferred← citeshttps://doi.org/10.70675/77959a81zcd04z45faz97e1ze254b7807703openalex-snapshot
Rôles des interférons dans la physiopathologie des myopathies inflammatoires
inferred← citeshttps://doi.org/10.7150/ijbs.48330openalex-snapshot
Immunoproteasome in IgA Nephropathy: State-of-Art and Future Perspectives
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