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A Potent Cross-Clade Neutralizing Human Monoclonal Antibody against a Novel Epitope on gp41 of Human Immunodeficiency Virus Type 1

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Anti-idiotypic antibody Ab2/3H6 mimics the epitope of the neutralizing anti-HIV-1 monoclonal antibody 2F5
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Protection of Macaques against Pathogenic Simian/Human Immunodeficiency Virus 89.6PD by Passive Transfer of Neutralizing Antibodies
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Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1016/j.vaccine.2018.07.010openalex-snapshot
Live rubella vectors can express native HIV envelope glycoproteins targeted by broadly neutralizing antibodies and prime the immune response to an envelope protein boost
inferred← citeshttps://doi.org/10.1016/j.virol.2005.08.030openalex-snapshot
Genetic analysis of heptad-repeat regions in the G2 fusion subunit of the Junín arenavirus envelope glycoprotein
inferred← citeshttps://doi.org/10.1016/j.virol.2005.11.019openalex-snapshot
Neutralization and infectivity characteristics of envelope glycoproteins from human immunodeficiency virus type 1 infected donors whose sera exhibit broadly cross-reactive neutralizing activity
inferred← citeshttps://doi.org/10.1016/j.virol.2006.04.012openalex-snapshot
Antigenic properties of a transport-competent influenza HA/HIV Env chimeric protein
inferred← citeshttps://doi.org/10.1016/j.virol.2006.07.056openalex-snapshot
Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaques
inferred← citeshttps://doi.org/10.1016/j.virol.2006.10.027openalex-snapshot
Resistance of HIV-1 to the broadly HIV-1-neutralizing, anti-carbohydrate antibody 2G12
inferred← citeshttps://doi.org/10.1016/j.virol.2007.01.015openalex-snapshot
Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies
inferred← citeshttps://doi.org/10.1016/j.virol.2007.05.024openalex-snapshot
Standardized assessment of NAb responses elicited in rhesus monkeys immunized with single- or multi-clade HIV-1 envelope immunogens
inferred← citeshttps://doi.org/10.1016/j.virol.2007.10.018openalex-snapshot
N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus
inferred← citeshttps://doi.org/10.1016/j.virol.2007.11.005openalex-snapshot
Analysis of the human immunodeficiency virus type 1 gp41 membrane proximal external region arrayed on hepatitis B surface antigen particles
inferred← citeshttps://doi.org/10.1016/j.virol.2007.11.009openalex-snapshot
Assessment of antibody responses against gp41 in HIV-1-infected patients using soluble gp41 fusion proteins and peptides derived from M group consensus envelope
inferred← citeshttps://doi.org/10.1016/j.virol.2008.04.005openalex-snapshot
Antibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics
inferred← citeshttps://doi.org/10.1016/j.virol.2009.05.015openalex-snapshot
Characterization of a trimeric MPER containing HIV-1 gp41 antigen
inferred← citeshttps://doi.org/10.1016/j.virol.2009.05.028openalex-snapshot
Changing sensitivity to broadly neutralizing antibodies b12, 2G12, 2F5, and 4E10 of primary subtype B human immunodeficiency virus type 1 variants in the natural course of infection
inferred← citeshttps://doi.org/10.1016/j.virol.2009.10.044openalex-snapshot
Epitopes for broad and potent neutralizing antibody responses during chronic infection with human immunodeficiency virus type 1
inferred← citeshttps://doi.org/10.1016/j.virol.2010.03.016openalex-snapshot
Residues in the membrane-spanning domain core modulate conformation and fusogenicity of the HIV-1 envelope glycoprotein
inferred← citeshttps://doi.org/10.1016/j.virol.2011.01.023openalex-snapshot
Immunological properties of the transmembrane envelope protein of the feline foamy virus and its use for serological screening
inferred← citeshttps://doi.org/10.1016/j.virol.2012.10.004openalex-snapshot
Broadly neutralizing antibodies against HIV-1: Templates for a vaccine
inferred← citeshttps://doi.org/10.1016/j.virol.2014.05.036openalex-snapshot
Efficacy of broadly neutralizing monoclonal antibody PG16 in HIV-infected humanized mice
inferred← citeshttps://doi.org/10.1016/j.virol.2014.06.006openalex-snapshot
Eliciting neutralizing antibodies with gp120 outer domain constructs based on M-group consensus sequence
inferred← citeshttps://doi.org/10.1016/j.virol.2014.10.036openalex-snapshot
Sequence variation of koala retrovirus transmembrane protein p15E among koalas from different geographic regions
inferred← citeshttps://doi.org/10.1016/j.virol.2015.09.010openalex-snapshot
Immunogenic properties of a trimeric gp41-based immunogen containing an exposed membrane-proximal external region
inferred← citeshttps://doi.org/10.1016/j.virol.2016.01.002openalex-snapshot
Modulating immunogenic properties of HIV-1 gp41 membrane-proximal external region by destabilizing six-helix bundle structure
inferred← citeshttps://doi.org/10.1016/j.virol.2016.09.011openalex-snapshot
Neutralization resistant HIV-1 primary isolates from antiretroviral naïve chronically infected children in India
inferred← citeshttps://doi.org/10.1016/j.virol.2017.02.015openalex-snapshot
Evaluation of a novel multi-immunogen vaccine strategy for targeting 4E10/10E8 neutralizing epitopes on HIV-1 gp41 membrane proximal external region
inferred← citeshttps://doi.org/10.1016/j.virusres.2010.04.006openalex-snapshot
Characterization of a SHIV162P3 variant evolved in an infected rhesus macaque with persistent plasma viremia
inferred← citeshttps://doi.org/10.1016/j.virusres.2019.197763openalex-snapshot
Effect of diversity in gp41 membrane proximal external region of primary HIV-1 Indian subtype C sequences on interaction with broadly neutralizing antibodies 4E10 and 10E8
inferred← citeshttps://doi.org/10.1016/s0264-410x(02)00389-4openalex-snapshot
Do not underestimate the power of antibodies—lessons from adoptive transfer of antibodies against HIV
inferred← citeshttps://doi.org/10.1016/s0952-7915(02)00362-xopenalex-snapshot
Neutralizing antibodies against HIV – back in the major leagues?
inferred← citeshttps://doi.org/10.1016/s0958-1669(02)00381-6openalex-snapshot
Anti-R7V antibodies as therapeutics for HIV-infected patients in failure of HAART
inferred← citeshttps://doi.org/10.1016/s1007-0214(05)70109-7openalex-snapshot
Monoclonal antibodies recognizing HIV-1 gp41 could inhibit env-mediated syncytium formation
inferred← citeshttps://doi.org/10.1016/s1054-3589(07)55002-7openalex-snapshot
Structure and Function of the HIV Envelope Glycoprotein as Entry Mediator, Vaccine Immunogen, and Target for Inhibitors
inferred← citeshttps://doi.org/10.1016/s1054-3589(07)56003-5openalex-snapshot
HIV‐1‐Specific Immune Response
inferred← citeshttps://doi.org/10.1016/s1473-3099(10)70069-4openalex-snapshot
Progress towards development of an HIV vaccine: report of the AIDS Vaccine 2009 Conference
inferred← citeshttps://doi.org/10.1021/acsinfecdis.0c00243openalex-snapshot
Cholesterol Constrains the Antigenic Configuration of the Membrane-Proximal Neutralizing HIV-1 Epitope
inferred← citeshttps://doi.org/10.1021/bi0612521openalex-snapshot
Structural Analysis and Assembly of the HIV-1 Gp41 Amino-Terminal Fusion Peptide and the Pretransmembrane Amphipathic-At-Interface Sequence
inferred← citeshttps://doi.org/10.1021/bi3016668openalex-snapshot
Anti-Idiotypic Monobodies Derived from a Fibronectin Scaffold
inferred← citeshttps://doi.org/10.1021/bi501171ropenalex-snapshot
The Membrane Proximal External Regions of gp41 from HIV-1 Strains HXB2 and JRFL Have Different Sensitivities to Alanine Mutation
inferred← citeshttps://doi.org/10.1021/bk-2006-0932.ch006openalex-snapshot
Carbohydrate-Based Vaccines against HIV/AIDS
inferred← citeshttps://doi.org/10.1021/bk-2012-1102.ch006openalex-snapshot
Carbohydrate-Based Vaccines against HIV/AIDS
inferred← citeshttps://doi.org/10.1038/cmi.2010.8openalex-snapshot
The good and evil of complement activation in HIV-1 infection
inferred← citeshttps://doi.org/10.1038/nature05818openalex-snapshot
Exploiting the defensive sugars of HIV-1 for drug and vaccine design
inferred← citeshttps://doi.org/10.1038/nature10373openalex-snapshot
Broad neutralization coverage of HIV by multiple highly potent antibodies
inferred← citeshttps://doi.org/10.1038/nchembio.1685openalex-snapshot
Recent strategies targeting HIV glycans in vaccine design
inferred← citeshttps://doi.org/10.1038/ncomms1100openalex-snapshot
B-cell depletion reveals a role for antibodies in the control of chronic HIV-1 infection
inferred← citeshttps://doi.org/10.1038/nm1244openalex-snapshot
Delay of HIV-1 rebound after cessation of antiretroviral therapy through passive transfer of human neutralizing antibodies
inferred← citeshttps://doi.org/10.1038/nrmicro1819openalex-snapshot
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus
inferred← citeshttps://doi.org/10.1038/nsmb.1944openalex-snapshot
Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region
inferred← citeshttps://doi.org/10.1038/nsmb.1950openalex-snapshot
Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies
inferred← citeshttps://doi.org/10.1038/nsmb.2922openalex-snapshot
Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies
inferred← citeshttps://doi.org/10.1038/s41401-025-01535-5openalex-snapshot
The conformational epitope of a gp41-specific mucosal protective IgA binds to the HIV-1 envelope and neutralizes infection
inferred← citeshttps://doi.org/10.1038/s41426-018-0087-0openalex-snapshot
Comparison of the genotypic and phenotypic properties of HIV-1 standard subtype B and subtype B/B’ env molecular clones derived from infections in China
inferred← citeshttps://doi.org/10.1038/s41467-023-42098-5openalex-snapshot
Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site
inferred← citeshttps://doi.org/10.1038/s41589-020-0496-yopenalex-snapshot
HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes
inferred← citeshttps://doi.org/10.1038/s41591-018-0042-6openalex-snapshot
Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
inferred← citeshttps://doi.org/10.1038/s41598-020-79327-6openalex-snapshot
Structure, membrane topology and influence of cholesterol of the membrane proximal region: transmembrane helical anchor sequence of gp41 from HIV
inferred← citeshttps://doi.org/10.1038/s42003-022-04219-6openalex-snapshot
Molecular recognition of a membrane-anchored HIV-1 pan-neutralizing epitope
inferred← citeshttps://doi.org/10.1038/scibx.2008.2openalex-snapshot
Simply irresistible?
inferred← citeshttps://doi.org/10.1038/srep45163openalex-snapshot
Cross-neutralizing anti-HIV-1 human single chain variable fragments(scFvs) against CD4 binding site and N332 glycan identified from a recombinant phage library
inferred← citeshttps://doi.org/10.1039/b419015gopenalex-snapshot
Synthesis of constrained helical peptides by thioether ligation: application to analogs of gp41
inferred← citeshttps://doi.org/10.1051/jbio/2015019openalex-snapshot
Vers un vaccin contre le VIH : des anticorps induits par un peptide de la gp41 neutralisent le virus et inhibent sa pathogénèse
inferred← citeshttps://doi.org/10.1073/pnas.0505126102openalex-snapshot
Antibody vs. HIV in a clash of evolutionary titans
inferred← citeshttps://doi.org/10.1073/pnas.0901474106openalex-snapshot
Broadly neutralizing anti-HIV-1 antibodies disrupt a hinge-related function of gp41 at the membrane interface
inferred← citeshttps://doi.org/10.1073/pnas.0908713106openalex-snapshot
Role of HIV membrane in neutralization by two broadly neutralizing antibodies
inferred← citeshttps://doi.org/10.1073/pnas.1004600107openalex-snapshot
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
inferred← citeshttps://doi.org/10.1073/pnas.1012923107openalex-snapshot
Scaffolding to build a rational vaccine design strategy
inferred← citeshttps://doi.org/10.1073/pnas.1204533109openalex-snapshot
HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120
inferred← citeshttps://doi.org/10.1073/pnas.1309842111openalex-snapshot
Structure of an HIV-1–neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer
inferred← citeshttps://doi.org/10.1073/pnas.1807259115openalex-snapshot
Structure of the membrane proximal external region of HIV-1 envelope glycoprotein
inferred← citeshttps://doi.org/10.1073/pnas.2112887119openalex-snapshot
Engineering pan–HIV-1 neutralization potency through multispecific antibody avidity
inferred← citeshttps://doi.org/10.1074/jbc.m110.111351openalex-snapshot
Structural Characterization of HIV gp41 with the Membrane-proximal External Region
inferred← citeshttps://doi.org/10.1074/jbc.m110.116699openalex-snapshot
Generation of a Family-specific Phage Library of Llama Single Chain Antibody Fragments That Neutralize HIV-1
inferred← citeshttps://doi.org/10.1074/jbc.m110.156588openalex-snapshot
Stabilized HIV-1 Envelope Glycoprotein Trimers Lacking the V1V2 Domain, Obtained by Virus Evolution
inferred← citeshttps://doi.org/10.1074/jbc.m111.224527openalex-snapshot
Genetic and Neutralization Sensitivity of Diverse HIV-1 env Clones from Chronically Infected Patients in China
inferred← citeshttps://doi.org/10.1074/jbc.m111.319863openalex-snapshot
A Monoclonal Antibody Directed against a Conformational Epitope of the HIV-1 Trans-activator (Tat) Protein Neutralizes Cross-clade
inferred← citeshttps://doi.org/10.1074/jbc.m114.569566openalex-snapshot
A Fusion Intermediate gp41 Immunogen Elicits Neutralizing Antibodies to HIV-1
inferred← citeshttps://doi.org/10.1074/jbc.m114.621185openalex-snapshot
Antigenicity and Immunogenicity of a Trimeric Envelope Protein from an Indian Clade C HIV-1 Isolate
inferred← citeshttps://doi.org/10.1074/jbc.m117.777714openalex-snapshot
SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins
inferred← citeshttps://doi.org/10.1074/jbc.m411088200openalex-snapshot
Trimeric Membrane-anchored gp41 Inhibits HIV Membrane Fusion
inferred← citeshttps://doi.org/10.1074/jbc.m412770200openalex-snapshot
Steric Accessibility of the HIV-1 gp41 N-trimer Region
inferred← citeshttps://doi.org/10.1074/jbc.m414515200openalex-snapshot
Design, Expression, and Immunogenicity of a Soluble HIV Trimeric Envelope Fragment Adopting a Prefusion gp41 Configuration
inferred← citeshttps://doi.org/10.1074/jbc.m605998200openalex-snapshot
Recognition and Blocking of HIV-1 gp41 Pre-transmembrane Sequence by Monoclonal 4E10 Antibody in a Raft-like Membrane Environment
inferred← citeshttps://doi.org/10.1074/jbc.ra119.009481openalex-snapshot
The lipid membrane of HIV-1 stabilizes the viral envelope glycoproteins and modulates their sensitivity to antibody neutralization
inferred← citeshttps://doi.org/10.1080/08982100701530159openalex-snapshot
One Step Membrane Incorporation of Viral Antigens as a Vaccine Candidate Against HIV
inferred← citeshttps://doi.org/10.1080/09205063.2014.940243openalex-snapshot
Carbohydrate-functionalized nanovaccines preserve HIV-1 antigen stability and activate antigen presenting cells
inferred← citeshttps://doi.org/10.1080/13543776.2018.1495708openalex-snapshot
HIV cure: global overview of bNAbs’ patents and related scientific publications
inferred← citeshttps://doi.org/10.1080/14760584.2019.1690458openalex-snapshot
Strategies for inducing effective neutralizing antibody responses against HIV-1
inferred← citeshttps://doi.org/10.1080/19420862.2016.1170263openalex-snapshot
A novel antibody discovery platform identifies anti-influenza A broadly neutralizing antibodies from human memory B cells
inferred← citeshttps://doi.org/10.1084/jem.20051639openalex-snapshot
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
inferred← citeshttps://doi.org/10.1084/jem.20091281openalex-snapshot
Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce β-chemokines
inferred← citeshttps://doi.org/10.1084/jem.20101907openalex-snapshot
MPER-specific antibodies induce gp120 shedding and irreversibly neutralize HIV-1
inferred← citeshttps://doi.org/10.1084/jem.20121827openalex-snapshot
Neutralizing antibodies to HIV-1 induced by immunization
inferred← citeshttps://doi.org/10.1084/jem.20121977openalex-snapshot
Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies
inferred← citeshttps://doi.org/10.1084/jem.20161765openalex-snapshot
Progress toward active or passive HIV-1 vaccination
inferred← citeshttps://doi.org/10.1084/jem.20180246openalex-snapshot
Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity
inferred← citeshttps://doi.org/10.1086/380102openalex-snapshot
Potent Cross‐Group Neutralization of Primary Human Immunodeficiency Virus Isolates with Monoclonal Antibodies—Implications for Acquired Immunodeficiency Syndrome Vaccine
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