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A randomized crossover trial on the effect of plant-based compared with animal-based meat on trimethylamine-N-oxide and cardiovascular disease risk factors in generally healthy adults: Study With Appetizing Plantfood—Meat Eating Alternative Trial (SWAP-MEAT)

https://doi.org/10.1093/ajcn/nqaa203
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1016/j.tem.2026.02.008openalex-snapshot
Trimethylamine-N-oxide: the microbial cue in immune-mediated disorders
inferred← citeshttps://doi.org/10.1016/j.tifs.2022.07.005openalex-snapshot
The rise of processed meat alternatives: A narrative review of the manufacturing, composition, nutritional profile and health effects of newer sources of protein, and their place in healthier diets
inferred← citeshttps://doi.org/10.1016/j.tifs.2023.104292openalex-snapshot
Plant-based dietary shift: Current trends, barriers, and carriers
inferred← citeshttps://doi.org/10.1016/j.tifs.2024.104483openalex-snapshot
The environmental impact, ingredient composition, nutritional and health impact of meat alternatives: A systematic review
inferred← citeshttps://doi.org/10.1016/j.tjnut.2022.10.016openalex-snapshot
Friend or Foe? The Role of Animal-Source Foods in Healthy and Environmentally Sustainable Diets
inferred← citeshttps://doi.org/10.1016/j.tjnut.2023.06.028openalex-snapshot
Dietary Guidelines Meet NOVA: Developing a Menu for A Healthy Dietary Pattern Using Ultra-Processed Foods
inferred← citeshttps://doi.org/10.1016/j.tjnut.2023.11.018openalex-snapshot
Evaluation of Protein Adequacy From Plant-Based Dietary Scenarios in Simulation Studies: A Narrative Review
inferred← citeshttps://doi.org/10.1016/j.tjnut.2025.10.028openalex-snapshot
Daily Consumption of Beef, Compared to Plant-Based Meat, for Eight Weeks Has No Effects on Cardiometabolic Risk Factors among Women of Reproductive Age with Low Iron Stores: A Randomized, Controlled Clinical Trial
inferred← citeshttps://doi.org/10.1016/j.urology.2023.03.012openalex-snapshot
Should Men Eat More Plants? A Systematic Review of the Literature on the Effect of Plant-Forward Diets on Men's Health
inferred← citeshttps://doi.org/10.1016/j.worlddev.2023.106316openalex-snapshot
Making meat and milk from plants: A review of plant-based food for human and planetary health
inferred← citeshttps://doi.org/10.1016/s2542-5196(24)00118-9openalex-snapshot
Estimated effects of reductions in processed meat consumption and unprocessed red meat consumption on occurrences of type 2 diabetes, cardiovascular disease, colorectal cancer, and mortality in the USA: a microsimulation study
inferred← citeshttps://doi.org/10.1016/s2542-5196(24)00305-xopenalex-snapshot
Recommendations to address the shortfalls of the EAT–Lancet planetary health diet from a plant-forward perspective
inferred← citeshttps://doi.org/10.1017/jns.2022.84openalex-snapshot
Assessing the effects of alternative plant-based meatsv. animal meats on biomarkers of inflammation: a secondary analysis of the SWAP-MEAT randomized crossover trial
inferred← citeshttps://doi.org/10.1017/jns.2026.10083openalex-snapshot
‘Do plant-based meats offer a steppingstone towards healthier choices? A cross-sectional audit of the UK market’
inferred← citeshttps://doi.org/10.1017/s002966512200266xopenalex-snapshot
Meeting report: plant-rich dietary patterns and health
inferred← citeshttps://doi.org/10.1017/s0029665123000034openalex-snapshot
Novel plant-based meat alternatives: future opportunities and health considerations
inferred← citeshttps://doi.org/10.1017/s0029665123004809openalex-snapshot
Harnessing the power on our plates: sustainable dietary patterns for public and planetary health
inferred← citeshttps://doi.org/10.1017/s0029665125100608openalex-snapshot
Are plant-based meat alternatives the stepping stone to healthier and more sustainable diets? A review of the literature
inferred← citeshttps://doi.org/10.1017/s1368980021002792openalex-snapshot
Nutritional marketing of plant-based meat-analogue products: an exploratory study of front-of-pack and website claims in the USA
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c07247openalex-snapshot
Recent Advances in the Processing and Manufacturing of Plant-Based Meat
inferred← citeshttps://doi.org/10.1021/acs.jafc.5c04034openalex-snapshot
Interactional Effects of Food Macronutrients with Gut Microbiome: Implications for Host Health and Risk
inferred← citeshttps://doi.org/10.1021/acs.jproteome.1c00851openalex-snapshot
Balancing the Equation: A Natural History of Trimethylamine and Trimethylamine-N-oxide
inferred← citeshttps://doi.org/10.1021/acssusresmgt.4c00075openalex-snapshot
Designing a More Sustainable and Environmentally Friendly Food Supply: A Roadmap for Future Food and Agricultural Research
inferred← citeshttps://doi.org/10.1038/s41430-022-01150-1openalex-snapshot
Red meat consumption and risk factors for type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1038/s41430-023-01340-5openalex-snapshot
Defining “plant-based meats”
inferred← citeshttps://doi.org/10.1038/s41430-024-01511-yopenalex-snapshot
Effects of carotenoid supplementation on glycemic control: a systematic review and meta-analysis of randomized clinical trials
inferred← citeshttps://doi.org/10.1038/s41430-026-01725-2openalex-snapshot
Plant-based meat alternatives: understanding the benefits and trade-offs for human and environmental health
inferred← citeshttps://doi.org/10.1038/s41430-026-01750-1openalex-snapshot
Trimethylamine N-oxide (TMAO) as a prognostic marker among patients at nutritional risk. A secondary analysis of the randomized clinical trial EFFORT
inferred← citeshttps://doi.org/10.1038/s41467-020-20061-yopenalex-snapshot
Plant-based and cell-based approaches to meat production
inferred← citeshttps://doi.org/10.1038/s41538-024-00292-9openalex-snapshot
Advancements in plant based meat analogs enhancing sensory and nutritional attributes
inferred← citeshttps://doi.org/10.1038/s41538-025-00577-7openalex-snapshot
The nutritional composition and impact on UK dietary intakes of meat and plant-based meat alternatives
inferred← citeshttps://doi.org/10.1038/s41598-021-93100-3openalex-snapshot
A metabolomics comparison of plant-based meat and grass-fed meat indicates large nutritional differences despite comparable Nutrition Facts panels
inferred← citeshttps://doi.org/10.1038/s41598-026-41165-3openalex-snapshot
Processed plant-based meat-supplemented diet versus red meat-based supplemented diet randomized cross-over trial Finding Optimal Oral Diet-1 (FOOD-1) trial
inferred← citeshttps://doi.org/10.1038/s41598-026-53056-8openalex-snapshot
Energy restriction and iron supplementation improve iron status in women with obesity regardless of red meat consumption: a randomized controlled trial
inferred← citeshttps://doi.org/10.1038/s43016-025-01148-5openalex-snapshot
Existing food processing classifications overlook the phytochemical composition of processed plant-based protein-rich foods
inferred← citeshttps://doi.org/10.1039/9781837678907-00232openalex-snapshot
Effect of a Vegetarian Diet on Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1039/d5fo01417dopenalex-snapshot
Gut microbiota mediated the curvilinear association between dietary animal protein intake and bone mineral density in Chinese adults
inferred← citeshttps://doi.org/10.1039/d5fo01876eopenalex-snapshot
Effects of vegan diets and lifestyle on adult body composition: a narrative review
inferred← citeshttps://doi.org/10.1055/a-1282-5097openalex-snapshot
Pflanzliche Fleischersatzprodukte sind gesunde Alternative zu rotem Fleisch
inferred← citeshttps://doi.org/10.1055/s-0043-1771381openalex-snapshot
Veganism and Oral Health—An Overview through the Perspective
inferred← citeshttps://doi.org/10.1055/s-013-58458openalex-snapshot
inferred← citeshttps://doi.org/10.1080/07853890.2025.2525403openalex-snapshot
Trimethylamine- N -oxide formation, the bacterial taxa involved and intervention strategies to reduce its concentration in the human body
inferred← citeshttps://doi.org/10.1080/09637486.2022.2078286openalex-snapshot
Nutritional assessment of plant-based meat analogues on the Swedish market
inferred← citeshttps://doi.org/10.1080/09637486.2023.2294685openalex-snapshot
Comparison of the low-calorie DASH diet and a low-calorie diet on serum TMAO concentrations and gut microbiota composition of adults with overweight/obesity: a randomized control trial
inferred← citeshttps://doi.org/10.1080/09637486.2024.2303029openalex-snapshot
Analysis of ingredient list and nutrient composition of plant-based burgers available in the global market
inferred← citeshttps://doi.org/10.1080/09637486.2024.2395810openalex-snapshot
Meat substitutes in Swedish school meals: nutritional quality, ingredients, and insights from meal planners
inferred← citeshttps://doi.org/10.1080/10408398.2022.2081666openalex-snapshot
Recent trends in design of healthier plant-based alternatives: nutritional profile, gastrointestinal digestion, and consumer perception
inferred← citeshttps://doi.org/10.1080/10408398.2022.2107997openalex-snapshot
Vegan nutrition: a preliminary guide for health professionals
inferred← citeshttps://doi.org/10.1080/10408398.2024.2392149openalex-snapshot
The role of fiber in modulating plant protein-induced metabolic responses
inferred← citeshttps://doi.org/10.1080/10408398.2025.2452362openalex-snapshot
Influence of dietary protein and fiber intake interactions on the human gut microbiota composition and function: a systematic review and network meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1080/15428052.2024.2345309openalex-snapshot
The Nexus of Plant-Based Markets, Technological Advancements, Health and Safety Protocols, and Future Trajectories
inferred← citeshttps://doi.org/10.1080/19490976.2026.2677951openalex-snapshot
Increasing plant protein sources in the diet modulates gut microbiota and tryptophan metabolism in men at cardiometabolic risk
inferred← citeshttps://doi.org/10.1080/87559129.2026.2635615openalex-snapshot
Exploring Alternative Proteins for Meat Industry: From Nutritional and Functional Properties to Recent Applications
inferred← citeshttps://doi.org/10.1086/720450openalex-snapshot
Increasing the Selection of Low-Carbon-Footprint Entrées through the Addition of New Menu Items and a Social Marketing Campaign in University Dining
inferred← citeshttps://doi.org/10.1089/ind.2021.29245.bwiopenalex-snapshot
Food for Thought: The Protein Transformation
inferred← citeshttps://doi.org/10.1093/advances/nmab073openalex-snapshot
A Scoping Review: Metabolomics Signatures Associated with Animal and Plant Protein Intake and Their Potential Relation with Cardiometabolic Risk
inferred← citeshttps://doi.org/10.1093/advances/nmac026openalex-snapshot
Perspective: Soy-based Meat and Dairy Alternatives, Despite Classification as Ultra-processed Foods, Deliver High-quality Nutrition on Par with Unprocessed or Minimally Processed Animal-based Counterparts
inferred← citeshttps://doi.org/10.1093/ajcn/nqaa253openalex-snapshot
The potential of novel plant protein foods to improve dietary patterns and markers of cardiovascular health
inferred← citeshttps://doi.org/10.1093/ajcn/nqaa385openalex-snapshot
“Instead of what,” and repeated 4-year interval change regarding red meat and T2D: increasing causal inference in nutritional epidemiology through methodological advances
inferred← citeshttps://doi.org/10.1093/ajcn/nqab108openalex-snapshot
Trimethylamine N-oxide variation in humans: the product of a diet–microbiota interaction?
inferred← citeshttps://doi.org/10.1093/ajcn/nqab414openalex-snapshot
Replacing meat with alternative plant-based products (RE-MAP): a randomized controlled trial of a multicomponent behavioral intervention to reduce meat consumption
inferred← citeshttps://doi.org/10.1093/ajcn/nqac041openalex-snapshot
Meat in the human diet: in transition from evolutionary hallmark to scapegoat
inferred← citeshttps://doi.org/10.1093/ajcn/nqac203openalex-snapshot
Low-carbohydrate vegan diets in diabetes for weight loss and sustainability: a randomized controlled trial
inferred← citeshttps://doi.org/10.1093/cdn/nzab133openalex-snapshot
Behavioral Characteristics and Self-Reported Health Status among 2029 Adults Consuming a “Carnivore Diet”
inferred← citeshttps://doi.org/10.1093/clinchem/hvad186openalex-snapshot
Contributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer
inferred← citeshttps://doi.org/10.1093/eurheartj/ehad336openalex-snapshot
Red meat consumption, cardiovascular diseases, and diabetes: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1093/eurjpc/zwad093openalex-snapshot
Role of microbiome in the cardiovascular continuum: relationship diet–microbiome and cardiovascular risk
inferred← citeshttps://doi.org/10.1093/ijfood/vvag151openalex-snapshot
Health and environmental implications of alternative proteins in human diets: nutritional value, gut microbiota modulation, and sustainability perspectives
inferred← citeshttps://doi.org/10.1093/jn/nxaa351openalex-snapshot
Plant-Based Meat and Dairy Substitutes as Appropriate Alternatives to Animal-Based Products?
inferred← citeshttps://doi.org/10.1093/nutrit/nuae031openalex-snapshot
Mapping the evidence of novel plant-based foods: a systematic review of nutritional, health, and environmental impacts in high-income countries
inferred← citeshttps://doi.org/10.1093/nutrit/nuaf234openalex-snapshot
Meat Intake in Relation to Metabolomic Signatures, Gut Microbiome, and Cardiovascular Disease Risk: A Narrative Review
inferred← citeshttps://doi.org/10.1093/nutrit/nuaf257openalex-snapshot
Parents’ and Children’s Perceptions and Attitudes Towards Traditional and Novel Plant-Based Meat Alternatives: A Scoping Review
inferred← citeshttps://doi.org/10.1093/nutrit/nuag058openalex-snapshot
Partially Replacing Animal-Based Protein Foods With Plant-Based Protein Foods: A Systematic Review of Randomized Controlled Trials in Healthy Adults
inferred← citeshttps://doi.org/10.1097/ppo.0000000000000649openalex-snapshot
Microbiome and Diet in Colon Cancer Development and Treatment
inferred← citeshttps://doi.org/10.1101/2021.08.07.21261731openalex-snapshot
Rapid Lifestyle Prototyping: Assessment of Infrared Spectroscopic Blood Responses for Short-term Lifestyle Interventions
inferred← citeshttps://doi.org/10.1101/2023.10.03.23296501openalex-snapshot
Diet order affects energy balance in randomized crossover feeding studies that vary in macronutrients but not ultra-processing
inferred← citeshttps://doi.org/10.1101/2024.08.27.24312650openalex-snapshot
Overlap between ultra-processed food and food that is high in fat, salt or sugar: analysis of 11 annual waves of the UK National Diet and Nutrition Survey 2008/09-2018/19
inferred← citeshttps://doi.org/10.1108/caer-05-2023-0130openalex-snapshot
Can we design food taxes to reduce agricultural greenhouse gas emissions in China? A perspective from animal protein intake of low-income populations
inferred← citeshttps://doi.org/10.1111/1541-4337.12925openalex-snapshot
Soy protein isolates: A review of their composition, aggregation, and gelation
inferred← citeshttps://doi.org/10.1111/1541-4337.13204openalex-snapshot
Ultraprocessed plant‐based foods: Designing the next generation of healthy and sustainable alternatives to animal‐based foods
inferred← citeshttps://doi.org/10.1111/1541-4337.70274openalex-snapshot
Nutritional Heterogeneity of Dietary Proteins: Mechanisms of Gut Microbiota‐Mediated Metabolic Regulation and Health Implications
inferred← citeshttps://doi.org/10.1111/1750-3841.17588openalex-snapshot
Ultra‐processed plant‐based analogs: Addressing the challenging journey toward health and safety
inferred← citeshttps://doi.org/10.1111/1750-3841.70039openalex-snapshot
Nova fails to appreciate the value of plant‐based meat and dairy alternatives in the diet
inferred← citeshttps://doi.org/10.1111/jhn.13218openalex-snapshot
Moving towards more sustainable diets: Is there potential for a personalised approach in practice?
inferred← citeshttps://doi.org/10.1111/jhn.13219openalex-snapshot
Meat versus meat alternatives: which is better for the environment and health? A nutritional and environmental analysis of animal‐based products compared with their plant‐based alternatives
inferred← citeshttps://doi.org/10.1136/bmjnph-2024-001035openalex-snapshot
Overlap between ultra-processed food and food that is high in fat, salt or sugar: analysis of 11 annual waves of the UK National Diet and Nutrition Survey 2008/2009–2018/2019
inferred← citeshttps://doi.org/10.1136/bmjnph-2025-001358openalex-snapshot
Not all ultra-processed foods are created equal: a review
inferred← citeshttps://doi.org/10.1139/apnm-2024-0498openalex-snapshot
Acute effects of a reformulated plant-based meat alternative compared to beef within a high-fat meal on inflammatory and metabolic factors: a randomized crossover trial
inferred← citeshttps://doi.org/10.1146/annurev-food-082421-114831openalex-snapshot
Gains and Losses of Agricultural Food Production: Implications for the Twenty-First Century
inferred← citeshttps://doi.org/10.1146/annurev-physiol-031522-092054openalex-snapshot
The Role of the Gut Microbiota in the Relationship Between Diet and Human Health
inferred← citeshttps://doi.org/10.1161/cir.0000000000001031openalex-snapshot
2021 Dietary Guidance to Improve Cardiovascular Health: A Scientific Statement From the American Heart Association
inferred← citeshttps://doi.org/10.1161/cir.0000000000001365openalex-snapshot
Ultraprocessed Foods and Their Association With Cardiometabolic Health: Evidence, Gaps, and Opportunities: A Science Advisory From the American Heart Association
inferred← citeshttps://doi.org/10.1161/hypertensionaha.125.17950openalex-snapshot
Food as Medicine for Hypertension: Microbiota as Mediators
inferred← citeshttps://doi.org/10.1161/jaha.121.021934openalex-snapshot
Fecal Microbiome Composition Does Not Predict Diet‐Induced TMAO Production in Healthy Adults
inferred← citeshttps://doi.org/10.1161/jaha.124.035034openalex-snapshot
Recipe for Heart Health: A Randomized Crossover Trial on Cardiometabolic Effects of Extra Virgin Olive Oil Within a Whole‐Food Plant‐Based Vegan Diet
inferred← citeshttps://doi.org/10.1161/jaha.125.041063openalex-snapshot
Effect of Varying Quantities of Lean Beef as Part of a Mediterranean‐Style Dietary Pattern on Gut Microbiota and Plasma, Fecal, and Urinary Metabolites: A Randomized Crossover Controlled Feeding Trial
inferred← citeshttps://doi.org/10.1177/0890117120960580dopenalex-snapshot
Nutrition Study Design Issues—Important Issues for Interpretation
inferred← citeshttps://doi.org/10.1177/08901171261447136openalex-snapshot
What Diet Trials Can and Can’t Tell Us – Mitigating Misinformation in Nutrition Science
inferred← citeshttps://doi.org/10.1177/08901171261473029openalex-snapshot
Ultraprocessed Foods and Public Policy: the Argument for Use-Case Consideration
inferred← citeshttps://doi.org/10.1177/15598276241237766openalex-snapshot
Health Benefits of a Plant-Based Dietary Pattern and Implementation in Healthcare and Clinical Practice
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