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CoV-AbDab: the coronavirus antibody database

https://doi.org/10.1093/bioinformatics/btaa739

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/rmv.706openalex-snapshot

Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, and therapeutic potential

inferredcites →https://doi.org/10.1016/j.antiviral.2016.06.003openalex-snapshot

Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infection

inferredcites →https://doi.org/10.1016/j.bbrc.2005.05.089openalex-snapshot

A human SARS-CoV neutralizing antibody against epitope on S2 protein

inferredcites →https://doi.org/10.1016/j.cell.2018.12.028openalex-snapshot

Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion

inferredcites →https://doi.org/10.1016/j.cell.2020.02.058openalex-snapshot

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

inferredcites →https://doi.org/10.1016/j.cell.2020.04.031openalex-snapshot

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies

inferredcites →https://doi.org/10.1016/j.celrep.2018.06.041openalex-snapshot

Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

inferredcites →https://doi.org/10.1016/j.celrep.2019.08.052openalex-snapshot

Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD

inferredcites →https://doi.org/10.1016/j.chom.2020.09.002openalex-snapshot

Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2

inferredcites →https://doi.org/10.1016/j.dci.2004.07.003openalex-snapshot

IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains

inferredcites →https://doi.org/10.1016/j.it.2020.03.007openalex-snapshot

Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses

inferredcites →https://doi.org/10.1016/j.jmb.2009.03.042openalex-snapshot

Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain

inferredcites →https://doi.org/10.1016/j.molimm.2004.06.032openalex-snapshot

Molecular characterization of a panel of murine monoclonal antibodies specific for the SARS-coronavirus

inferredcites →https://doi.org/10.1016/j.virol.2006.09.029openalex-snapshot

Generation and characterization of human monoclonal neutralizing antibodies with distinct binding and sequence features against SARS coronavirus using XenoMouse®

inferredcites →https://doi.org/10.1016/s0145-305x(02)00039-3openalex-snapshot

IMGT unique numbering for immunoglobulin and T cell receptor variable domains and Ig superfamily V-like domains

inferredcites →https://doi.org/10.1038/cr.2013.92openalex-snapshot

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

inferredcites →https://doi.org/10.1038/cr.2015.113openalex-snapshot

A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein

inferredcites →https://doi.org/10.1038/nature12328openalex-snapshot

Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26

inferredcites →https://doi.org/10.1038/ncomms15092openalex-snapshot

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

inferredcites →https://doi.org/10.1038/ncomms6945openalex-snapshot

Quorum sensing triggers the stochastic escape of individual cells from Pseudomonas putida biofilms

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Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing

inferredcites →https://doi.org/10.1038/s41423-020-0426-7openalex-snapshot

Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor

inferredcites →https://doi.org/10.1038/s41467-019-09078-0openalex-snapshot

SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells

inferredcites →https://doi.org/10.1038/s41467-020-16256-yopenalex-snapshot

A human monoclonal antibody blocking SARS-CoV-2 infection

inferredcites →https://doi.org/10.1038/s41577-020-0311-8openalex-snapshot

The trinity of COVID-19: immunity, inflammation and intervention

inferredcites →https://doi.org/10.1038/s41577-020-0321-6openalex-snapshot

The potential danger of suboptimal antibody responses in COVID-19

inferredcites →https://doi.org/10.1038/s41586-020-2180-5openalex-snapshot

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

inferredcites →https://doi.org/10.1038/s41586-020-2349-yopenalex-snapshot

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

inferredcites →https://doi.org/10.1038/s41586-020-2380-zopenalex-snapshot

Human neutralizing antibodies elicited by SARS-CoV-2 infection

inferredcites →https://doi.org/10.1038/s41586-020-2456-9openalex-snapshot

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

inferredcites →https://doi.org/10.1038/s41591-020-0901-9openalex-snapshot

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

inferredcites →https://doi.org/10.1038/s41591-020-0913-5openalex-snapshot

A serological assay to detect SARS-CoV-2 seroconversion in humans

inferredcites →https://doi.org/10.1038/s41591-020-0998-xopenalex-snapshot

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

inferredcites →https://doi.org/10.1038/srep20842openalex-snapshot

IGHV1-69 polymorphism modulates anti-influenza antibody repertoires, correlates with IGHV utilization shifts and varies by ethnicity

inferredcites →https://doi.org/10.1073/pnas.1402074111openalex-snapshot

Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

inferredcites →https://doi.org/10.1073/pnas.1510199112openalex-snapshot

Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus

inferredcites →https://doi.org/10.1073/pnas.1510830112openalex-snapshot

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection

inferredcites →https://doi.org/10.1073/pnas.1707304114openalex-snapshot

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen

inferredcites →https://doi.org/10.1074/jbc.m600697200openalex-snapshot

Structure of Severe Acute Respiratory Syndrome Coronavirus Receptor-binding Domain Complexed with Neutralizing Antibody

inferredcites →https://doi.org/10.1074/jbc.m603275200openalex-snapshot

Structural Basis of Neutralization by a Human Anti-severe Acute Respiratory Syndrome Spike Protein Antibody, 80R

inferredcites →https://doi.org/10.1080/14728222.2017.1271415openalex-snapshot

MERS-CoV spike protein: a key target for antivirals

inferredcites →https://doi.org/10.1080/19420862.2016.1205773openalex-snapshot

ABodyBuilder: Automated antibody structure prediction with data–driven accuracy estimation

inferredcites →https://doi.org/10.1080/22221751.2019.1597644openalex-snapshot

Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein

inferredcites →https://doi.org/10.1086/500143openalex-snapshot

Therapy with a Severe Acute Respiratory Syndrome–Associated Coronavirus–Neutralizing Human Monoclonal Antibody Reduces Disease Severity and Viral Burden in Golden Syrian Hamsters

inferredcites →https://doi.org/10.1093/bioinformatics/btv552openalex-snapshot

ANARCI: antigen receptor numbering and receptor classification

inferredcites →https://doi.org/10.1093/cid/ciaa344openalex-snapshot

Antibody Responses to SARS-CoV-2 in Patients With Novel Coronavirus Disease 2019

inferredcites →https://doi.org/10.1093/infdis/jix209openalex-snapshot

Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset

inferredcites →https://doi.org/10.1093/infdis/jiy311openalex-snapshot

Ultrapotent Human Neutralizing Antibody Repertoires Against Middle East Respiratory Syndrome Coronavirus From a Recovered Patient

inferredcites →https://doi.org/10.1093/nar/28.1.235openalex-snapshot

The Protein Data Bank

inferredcites →https://doi.org/10.1093/nar/gkt1043openalex-snapshot

SAbDab: the structural antibody database

inferredcites →https://doi.org/10.1101/2020.04.03.024885openalex-snapshot

Rapid in silico design of antibodies targeting SARS-CoV-2 using machine learning and supercomputing

inferredcites →https://doi.org/10.1101/2020.04.16.045419openalex-snapshot

Sybodies targeting the SARS-CoV-2 receptor-binding domain

inferredcites →https://doi.org/10.1101/2020.05.12.091298openalex-snapshot

Characterization of neutralizing antibodies from a SARS-CoV-2 infected individual

inferredcites →https://doi.org/10.1101/gr.849004openalex-snapshot

WebLogo: A Sequence Logo Generator: Figure 1

inferredcites →https://doi.org/10.1126/sciadv.aas9667openalex-snapshot

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection

inferredcites →https://doi.org/10.1126/science.1116480openalex-snapshot

Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor

inferredcites →https://doi.org/10.1126/science.abb2507openalex-snapshot

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

inferredcites →https://doi.org/10.1126/science.abb2762openalex-snapshot

Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2

inferredcites →https://doi.org/10.1126/science.abb7269openalex-snapshot

A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV

inferredcites →https://doi.org/10.1126/science.abb9983openalex-snapshot

Site-specific glycan analysis of the SARS-CoV-2 spike

inferredcites →https://doi.org/10.1126/science.abc2241openalex-snapshot

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2

inferredcites →https://doi.org/10.1126/science.abc5902openalex-snapshot

Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability

inferredcites →https://doi.org/10.1126/science.abc7520openalex-snapshot

Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model

inferredcites →https://doi.org/10.1126/science.abd0827openalex-snapshot

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

inferredcites →https://doi.org/10.1126/scitranslmed.3008140openalex-snapshot

Potent Neutralization of MERS-CoV by Human Neutralizing Monoclonal Antibodies to the Viral Spike Glycoprotein

inferredcites →https://doi.org/10.1128/jvi.00433-14openalex-snapshot

A Conformation-Dependent Neutralizing Monoclonal Antibody Specifically Targeting Receptor-Binding Domain in Middle East Respiratory Syndrome Coronavirus Spike Protein

inferredcites →https://doi.org/10.1128/jvi.00837-18openalex-snapshot

A Novel Nanobody Targeting Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Receptor-Binding Domain Has Potent Cross-Neutralizing Activity and Protective Efficacy against MERS-CoV

inferredcites →https://doi.org/10.1128/jvi.00912-14openalex-snapshot

Exceptionally Potent Neutralization of Middle East Respiratory Syndrome Coronavirus by Human Monoclonal Antibodies

inferredcites →https://doi.org/10.1128/jvi.02002-17openalex-snapshot

Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape

inferredcites →https://doi.org/10.1128/jvi.02377-07openalex-snapshot

Structural Basis for Potent Cross-Neutralizing Human Monoclonal Antibody Protection against Lethal Human and Zoonotic Severe Acute Respiratory Syndrome Coronavirus Challenge

inferredcites →https://doi.org/10.1128/jvi.79.3.1635-1644.2005openalex-snapshot

Molecular and Biological Characterization of Human Monoclonal Antibodies Binding to the Spike and Nucleocapsid Proteins of Severe Acute Respiratory Syndrome Coronavirus

inferredcites →https://doi.org/10.12932/ap-200220-0773openalex-snapshot

Perspectives on monoclonal antibody therapy as potential therapeutic intervention for Coronavirus disease-19 (COVID-19)

inferredcites →https://doi.org/10.1371/journal.pmed.0030237openalex-snapshot

Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants

inferredcites →https://doi.org/10.1371/journal.ppat.1000092openalex-snapshot

Temperature, Viral Genetics, and the Transmission of West Nile Virus by Culex pipiens Mosquitoes

inferredcites →https://doi.org/10.1371/journal.ppat.1002859openalex-snapshot

Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies

inferredcites →https://doi.org/10.3390/v11010060openalex-snapshot

Advances in MERS-CoV Vaccines and Therapeutics Based on the Receptor-Binding Domain

inferredcites →https://doi.org/10.4049/jimmunol.1800708openalex-snapshot

Observed Antibody Space: A Resource for Data Mining Next-Generation Sequencing of Antibody Repertoires

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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DeepInterAware: Deep Interaction Interface‐Aware Network for Improving Antigen‐Antibody Interaction Prediction from Sequence Data

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Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

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No association of malignant B‐cell non‐Hodgkin lymphomas with ipsilateral SARS‐CoV ‐2 vaccination

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Somatic Hypermutations Enhance Neutralization Breadth of IGHV3‐53/3‐66 Public Antibodies Against SARS‐CoV‐2 Variants

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Analysis of B‐cell receptor repertoire to evaluate immunogenicity of monovalent Omicron XBB.1.5 mRNA vaccines

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Characterization of B‐cell receptor clonality and immunoglobulin gene usage at multiple time points during active SARS‐CoV‐2 infection

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Comparative single‐cell RNA sequencing analysis of immune response to inactivated vaccine and natural SARS‐CoV‐2 infection

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VDDB: A comprehensive resource and machine learning tool for antiviral drug discovery

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gcCov: Linked open data for global coronavirus studies

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A novel consensus‐based computational pipeline for screening of antibody therapeutics for efficacy against SARS‐CoV‐2 variants of concern including Omicron variant

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Dynamical changes of SARS‐CoV ‐2 spike variants in the highly immunogenic regions impact the viral antibodies escaping

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AbDPP: Target‐oriented antibody design with pretraining and prior biological structure knowledge

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Clinical efficacy of anti‐SARS‐CoV‐2 monoclonal antibodies in preventing hospitalisation and mortality among patients infected with Omicron variants: A systematic review and meta‐analysis

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In Silico Tools for Predicting Novel Epitopes

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Structure-Based Epitope Profiling with the Structural Profiling of Antibodies to Cluster by Epitope 2 (SPACE2) Algorithm

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B Cell Epitope Mapping by High-Density Competition ELISAs

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Coronaviruses: Pandemic SARS-CoV-2

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A Survey on Covid-19 Knowledge Graphs and Their Data Sources

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SARS-CoV-2 Spike Opening Dynamics and Energetics Reveal the Individual Roles of Glycans and Their Collective Impact

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Ab2Nb: A Physics-Guided Framework for Converting Antibodies into Nanobodies

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AI-Driven Design Platforms of Next-Generation Antibody Therapeutics

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Targeted photodynamic neutralization of SARS-CoV-2 mediated by singlet oxygen

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Databases, DrugBank, and virtual screening platforms for therapeutic development

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Systems biology in COVID-19

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Vaccine development strategies and impact

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Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants

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Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies

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Early warning of emerging infectious diseases based on multimodal data

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COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas

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A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

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Macrophages direct location-dependent recall of B cell memory to vaccination

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Generation of antigen-specific paired-chain antibodies using large language models

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Potent neutralization of SARS-CoV-2 variants of concern by an antibody with an uncommon genetic signature and structural mode of spike recognition

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SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display

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B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination

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ChAdOx1 nCoV-19 vaccine elicits monoclonal antibodies with cross-neutralizing activity against SARS-CoV-2 viral variants

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Progressive loss of conserved spike protein neutralizing antibody sites in Omicron sublineages is balanced by preserved T cell immunity

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Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly

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Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron

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Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain

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Clonotype-enriched somatic hypermutations drive affinity maturation of a public human antibody targeting an occluded sarbecovirus epitope

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Affinity maturation and light-chain-mediated paratope diversification anticipates viral evolution

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In vivo evolution of antibody CR3022 expands cross-neutralization of SARS-CoV-2 variants and informs pan-sarbecovirus immunity

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Public antibody clonotypes and deep learning identify SARS-CoV-2 and HIV broadly neutralizing antibodies in immune repertoires

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One thousand SARS-CoV-2 antibody structures reveal convergent binding and near-universal immune escape

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SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns

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Rational design of a booster vaccine against COVID-19 based on antigenic distance

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Convergent CDR3 homology amongst Spike-specific antibody responses in convalescent COVID-19 subjects receiving the BNT162b2 vaccine

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AI models for protein design are driving antibody engineering

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Mining adaptive immune receptor repertoires for biological and clinical information using machine learning

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Reviewing methods of deep learning for diagnosing COVID-19, its variants and synergistic medicine combinations

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Fast clonal family inference from large-scale B cell repertoire sequencing data

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Computational approach for binding prediction of SARS-CoV-2 with neutralizing antibodies

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Applying the digital data and the bioinformatics tools in SARS-CoV-2 research

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Improving antibody optimization ability of generative adversarial network through large language model

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A comprehensive overview of recent advances in generative models for antibodies

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Web resources facilitate drug discovery in treatment of COVID-19

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Ultrapotent class I neutralizing antibodies post Omicron breakthrough infection overcome broad SARS-CoV-2 escape variants

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Enabling the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants including KP.2

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Dual strategies for durable antibodies against SARS-CoV-2: Immune trajectories and viral fitness constraints

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Novel skewed usage of B-cell receptors in COVID-19 patients with various clinical presentations

inferred← citeshttps://doi.org/10.1016/j.immuni.2021.08.025openalex-snapshot

A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site

inferred← citeshttps://doi.org/10.1016/j.immuni.2021.10.019openalex-snapshot

Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability

inferred← citeshttps://doi.org/10.1016/j.immuni.2022.03.019openalex-snapshot

A large-scale systematic survey reveals recurring molecular features of public antibody responses to SARS-CoV-2

inferred← citeshttps://doi.org/10.1016/j.immuni.2023.11.004openalex-snapshot

Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants

inferred← citeshttps://doi.org/10.1016/j.immuni.2024.07.022openalex-snapshot

An explainable language model for antibody specificity prediction using curated influenza hemagglutinin antibodies

inferred← citeshttps://doi.org/10.1016/j.immuni.2026.03.006openalex-snapshot

Multiplexed antigen panel analysis identifies B cell phenotype and receptor genetic contributions to antibody breadth

inferred← citeshttps://doi.org/10.1016/j.immuno.2025.100057openalex-snapshot

Is the vaccination-induced B cell receptor repertoire predictable?

inferred← citeshttps://doi.org/10.1016/j.isci.2022.103951openalex-snapshot

No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults

inferred← citeshttps://doi.org/10.1016/j.isci.2022.105259openalex-snapshot

Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2

inferred← citeshttps://doi.org/10.1016/j.isci.2023.106260openalex-snapshot

Demultiplexing Ig repertoires by parallel mRNA/DNA sequencing shows major differential alterations in severe COVID-19

inferred← citeshttps://doi.org/10.1016/j.isci.2023.106562openalex-snapshot

19n01, a broadly neutralizing antibody against omicron BA.1, BA.2, BA.4/5, and other SARS-CoV-2 variants of concern

inferred← citeshttps://doi.org/10.1016/j.isci.2023.108009openalex-snapshot

Broad SARS-CoV-2 neutralization by monoclonal and bispecific antibodies derived from a Gamma-infected individual

inferred← citeshttps://doi.org/10.1016/j.isci.2024.110208openalex-snapshot

A cryptic site in class 5 epitope of SARS-CoV-2 RBD maintains highly conservation across natural isolates

inferred← citeshttps://doi.org/10.1016/j.isci.2026.117693openalex-snapshot

An inverse-protein-folding pre-trained model for predicting the mutational effects in protein-protein interactions

inferred← citeshttps://doi.org/10.1016/j.it.2022.11.001openalex-snapshot

The evolutionary and functional significance of germline immunoglobulin gene variation

inferred← citeshttps://doi.org/10.1016/j.jaci.2025.02.026openalex-snapshot

Prior SARS-CoV-2 infection affects adaptive immune responses to Omicron BA.4/BA.5 mRNA booster

inferred← citeshttps://doi.org/10.1016/j.jbi.2026.105097openalex-snapshot

PAC-Net: A physics-guided multimodal hybrid network for antibody-antigen interaction prediction

inferred← citeshttps://doi.org/10.1016/j.jinf.2023.10.020openalex-snapshot

Memory B cells anticipate SARS-CoV-2 variants through somatic hypermutation

inferred← citeshttps://doi.org/10.1016/j.jmb.2025.169509openalex-snapshot

HeavyBuilder: Analysis of High-Throughput of Antibody Heavy Chain Repertoires in the Structural Space

inferred← citeshttps://doi.org/10.1016/j.jsb.2023.108042openalex-snapshot

Predicting virus Fitness: Towards a structure-based computational model

inferred← citeshttps://doi.org/10.1016/j.mcpro.2023.100690openalex-snapshot

Into the Dark Serum Proteome: Personalized Features of IgG1 and IgA1 Repertoires in Severe COVID-19 Patients

inferred← citeshttps://doi.org/10.1016/j.patter.2024.100967openalex-snapshot

Improving antibody language models with native pairing

inferred← citeshttps://doi.org/10.1016/j.patter.2025.101239openalex-snapshot

Focused learning by antibody language models using preferential masking of non-templated regions

inferred← citeshttps://doi.org/10.1016/j.patter.2025.101419openalex-snapshot

Contrastive learning enables epitope overlap predictions for targeted antibody discovery

inferred← citeshttps://doi.org/10.1016/j.str.2021.05.014openalex-snapshot

Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies

inferred← citeshttps://doi.org/10.1016/j.str.2023.04.010openalex-snapshot

Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response

inferred← citeshttps://doi.org/10.1016/j.str.2023.06.005openalex-snapshot

Major classes of neutralizing antibodies evaded by the SARS-CoV-2 Omicron variant

inferred← citeshttps://doi.org/10.1016/j.str.2024.08.022openalex-snapshot

Discovery and characterization of a pan-betacoronavirus S2-binding antibody

inferred← citeshttps://doi.org/10.1016/j.tim.2020.12.006openalex-snapshot

Slaying SARS-CoV-2 One (Single-domain) Antibody at a Time

inferred← citeshttps://doi.org/10.1016/j.tips.2022.12.005openalex-snapshot

Computational and artificial intelligence-based methods for antibody development

inferred← citeshttps://doi.org/10.1016/j.wpi.2022.102094openalex-snapshot

Searching and Analyzing Patent-relevant COVID-19 Information

inferred← citeshttps://doi.org/10.1016/j.xcrm.2023.101267openalex-snapshot

SARS-CoV-2 antibodies from children exhibit broad neutralization and belong to adult public clonotypes

inferred← citeshttps://doi.org/10.1016/j.xcrm.2024.101577openalex-snapshot

Structural basis of broad SARS-CoV-2 cross-neutralization by affinity-matured public antibodies

inferred← citeshttps://doi.org/10.1016/j.xcrm.2024.101668openalex-snapshot

Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination

inferred← citeshttps://doi.org/10.1016/j.xpro.2024.102969openalex-snapshot

Protocol for fast clonal family inference and analysis from large-scale B cell receptor repertoire sequencing data

inferred← citeshttps://doi.org/10.1016/j.ymthe.2022.09.010openalex-snapshot

Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery

inferred← citeshttps://doi.org/10.1021/acs.biochem.4c00385openalex-snapshot

A Biparatopic Intrabody Renders Vero Cells Impervious to Ricin Intoxication

inferred← citeshttps://doi.org/10.1021/acs.jcim.1c01523openalex-snapshot

SARS-CoV-2 Delta Variant Decreases Nanobody Binding and ACE2 Blocking Effectivity

inferred← citeshttps://doi.org/10.1021/acs.jcim.4c01023openalex-snapshot

Evaluation of an Affinity-Enhanced Anti-SARS-CoV2 Nanobody Design Workflow Using Machine Learning and Molecular Dynamics

inferred← citeshttps://doi.org/10.1021/acs.jcim.5c00973openalex-snapshot

Predicting Antibody–Antigen Interactions with Structure-Aware LLMs: Insights from SARS-CoV-2 Variants

inferred← citeshttps://doi.org/10.1021/acs.jcim.6c00716openalex-snapshot

Adaptive Disorder as the Hallmark of Nanobodies Antigen-Binding Loops

inferred← citeshttps://doi.org/10.1021/acscentsci.1c00216openalex-snapshot

Molecular Aspects Concerning the Use of the SARS-CoV‑2 Receptor Binding Domain as a Target for Preventive Vaccines

inferred← citeshttps://doi.org/10.1021/acsinfecdis.4c00015openalex-snapshot

Enhanced Surface Accessibility of SARS-CoV-2 Omicron Spike Protein Due to an Altered Glycosylation Profile

inferred← citeshttps://doi.org/10.1021/acsptsci.1c00058openalex-snapshot

Identification of Novel Neutralizing Monoclonal Antibodies against SARS-CoV-2 Spike Glycoprotein

inferred← citeshttps://doi.org/10.1021/acsptsci.3c00317openalex-snapshot

Screening Peptide Drug Candidates To Neutralize Whole Viral Agents: A Case Study with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

inferred← citeshttps://doi.org/10.1021/jacs.1c03945openalex-snapshot

NMR Based SARS-CoV-2 Antibody Screening

inferred← citeshttps://doi.org/10.1038/d41586-021-03796-6openalex-snapshot

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

inferred← citeshttps://doi.org/10.1038/s41401-021-00851-wopenalex-snapshot

Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19

inferred← citeshttps://doi.org/10.1038/s41422-022-00727-6openalex-snapshot

Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant

inferred← citeshttps://doi.org/10.1038/s41467-021-27799-zopenalex-snapshot

A pandemic-enabled comparison of discovery platforms demonstrates a naive antibody library can match the best immune-sourced antibodies

inferred← citeshttps://doi.org/10.1038/s41467-022-31142-5openalex-snapshot

Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine

inferred← citeshttps://doi.org/10.1038/s41467-022-32232-0openalex-snapshot

A public antibody class recognizes an S2 epitope exposed on open conformations of SARS-CoV-2 spike

inferred← citeshttps://doi.org/10.1038/s41467-023-36761-0openalex-snapshot

Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants

inferred← citeshttps://doi.org/10.1038/s41467-023-43420-xopenalex-snapshot

Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates

inferred← citeshttps://doi.org/10.1038/s41467-024-45050-3openalex-snapshot

Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants

inferred← citeshttps://doi.org/10.1038/s41467-024-47743-1openalex-snapshot

An ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutation

inferred← citeshttps://doi.org/10.1038/s41467-024-50903-yopenalex-snapshot

De novo generation of SARS-CoV-2 antibody CDRH3 with a pre-trained generative large language model

inferred← citeshttps://doi.org/10.1038/s41467-024-51770-3openalex-snapshot

Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein and potentially drive the genesis of Omicron variants

inferred← citeshttps://doi.org/10.1038/s41467-024-53105-8openalex-snapshot

De novo protein sequencing of antibodies for identification of neutralizing antibodies in human plasma post SARS-CoV-2 vaccination

inferred← citeshttps://doi.org/10.1038/s41467-025-67361-9openalex-snapshot

De novo design of epitope-specific antibodies via a structure-driven computational workflow

inferred← citeshttps://doi.org/10.1038/s41467-025-67971-3openalex-snapshot

Learning the language of protein-protein interactions

inferred← citeshttps://doi.org/10.1038/s41467-026-70553-6openalex-snapshot

Mining antibody functionality via AI-guided structural landscape profiling

inferred← citeshttps://doi.org/10.1038/s41540-024-00432-7openalex-snapshot

EpiScan: accurate high-throughput mapping of antibody-specific epitopes using sequence information

inferred← citeshttps://doi.org/10.1038/s41551-025-01353-4openalex-snapshot

Deep mutational learning for the selection of therapeutic antibodies resistant to the evolution of Omicron variants of SARS-CoV-2

inferred← citeshttps://doi.org/10.1038/s41586-021-03739-1openalex-snapshot

Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2

inferred← citeshttps://doi.org/10.1038/s41586-021-04385-3openalex-snapshot

Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies

inferred← citeshttps://doi.org/10.1038/s41586-024-07748-8openalex-snapshot

Immunological memory diversity in the human upper airway

inferred← citeshttps://doi.org/10.1038/s41587-021-01065-5openalex-snapshot

Single-cell profiling of proteins and chromatin accessibility using PHAGE-ATAC

inferred← citeshttps://doi.org/10.1038/s41587-023-01763-2openalex-snapshot

Efficient evolution of human antibodies from general protein language models

inferred← citeshttps://doi.org/10.1038/s41587-024-02346-5openalex-snapshot

Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells

inferred← citeshttps://doi.org/10.1038/s41587-024-02469-9openalex-snapshot

AIntibody: an experimentally validated in silico antibody discovery design challenge

inferred← citeshttps://doi.org/10.1038/s41589-022-01140-1openalex-snapshot

Converting non-neutralizing SARS-CoV-2 antibodies into broad-spectrum inhibitors

inferred← citeshttps://doi.org/10.1038/s41590-022-01367-zopenalex-snapshot

Adaptive immune responses to SARS-CoV-2 persist in the pharyngeal lymphoid tissue of children

inferred← citeshttps://doi.org/10.1038/s41590-024-02064-9openalex-snapshot

Temporal profiling of human lymphoid tissues reveals coordinated defense against viral challenge

inferred← citeshttps://doi.org/10.1038/s41598-020-79036-0openalex-snapshot

High affinity nanobodies block SARS-CoV-2 spike receptor binding domain interaction with human angiotensin converting enzyme

inferred← citeshttps://doi.org/10.1038/s41598-021-89621-6openalex-snapshot

Exploring antibody repurposing for COVID-19: beyond presumed roles of therapeutic antibodies

inferred← citeshttps://doi.org/10.1038/s41598-024-80474-3openalex-snapshot

COVID-AMD database for coronavirus-infected animal models with comparative analysis tools

inferred← citeshttps://doi.org/10.1038/s42003-022-03630-3openalex-snapshot

A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron

inferred← citeshttps://doi.org/10.1038/s42003-022-04138-6openalex-snapshot

SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact

inferred← citeshttps://doi.org/10.1038/s42003-023-05332-wopenalex-snapshot

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

inferred← citeshttps://doi.org/10.1038/s42003-023-05744-8openalex-snapshot

Contextualising the developability risk of antibodies with lambda light chains using enhanced therapeutic antibody profiling

inferred← citeshttps://doi.org/10.1038/s42003-024-06500-2openalex-snapshot

Two-dimensional high-throughput on-cell screening of immunoglobulins against broad antigen repertoires

inferred← citeshttps://doi.org/10.1038/s42003-024-06951-7openalex-snapshot

Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages

inferred← citeshttps://doi.org/10.1038/s42003-025-07827-0openalex-snapshot

Structural and virological identification of neutralizing antibody footprint provides insights into therapeutic antibody design against SARS-CoV-2 variants

inferred← citeshttps://doi.org/10.1038/s42256-022-00492-6openalex-snapshot

Interpreting the B-cell receptor repertoire with single-cell gene expression using Benisse

inferred← citeshttps://doi.org/10.1038/s42256-022-00553-wopenalex-snapshot

Predicting unseen antibodies’ neutralizability via adaptive graph neural networks

inferred← citeshttps://doi.org/10.1038/s42256-025-01089-5openalex-snapshot

Training data composition determines machine learning generalization and biological rule discovery

inferred← citeshttps://doi.org/10.1038/s43586-023-00284-1openalex-snapshot

Adaptive immune receptor repertoire analysis

inferred← citeshttps://doi.org/10.1038/s43588-022-00372-4openalex-snapshot

Unconstrained generation of synthetic antibody–antigen structures to guide machine learning methodology for antibody specificity prediction

inferred← citeshttps://doi.org/10.1038/s44222-026-00444-4openalex-snapshot

Multi-objective antibody design and optimization using machine learning

inferred← citeshttps://doi.org/10.1073/pnas.2116730119openalex-snapshot

Specialized interferon action in COVID-19

inferred← citeshttps://doi.org/10.1073/pnas.2201541119openalex-snapshot

Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19

inferred← citeshttps://doi.org/10.1073/pnas.2401058121openalex-snapshot

Computational detection of antigen-specific B cell receptors following immunization

inferred← citeshttps://doi.org/10.1073/pnas.2410529121openalex-snapshot

Improved deep learning prediction of antigen–antibody interactions

inferred← citeshttps://doi.org/10.1073/pnas.2412787122openalex-snapshot

Retrospective SARS-CoV-2 human antibody development trajectories are largely sparse and permissive

inferred← citeshttps://doi.org/10.1073/pnas.2535385123openalex-snapshot

A structural and mechanistic atlas of NTD antibody neutralization and immune escape across SARS-CoV-2 prototype and its (sub-)variants

inferred← citeshttps://doi.org/10.1080/07853890.2024.2304108openalex-snapshot

Novel graph-based machine-learning technique for viral infectious diseases: application to influenza and hepatitis diseases

inferred← citeshttps://doi.org/10.1080/08927022.2022.2111421openalex-snapshot

Epitopes mapped onto SARS-CoV-2 receptor-binding motif by five distinct human neutralising antibodies

inferred← citeshttps://doi.org/10.1080/19420862.2020.1869406openalex-snapshot

A computational method for immune repertoire mining that identifies novel binders from different clonotypes, demonstrated by identifying anti-pertussis toxoid antibodies

inferred← citeshttps://doi.org/10.1080/19420862.2021.1996732openalex-snapshot

Current strategies for detecting functional convergence across B-cell receptor repertoires

inferred← citeshttps://doi.org/10.1080/19420862.2021.2008790openalex-snapshot

Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies

inferred← citeshttps://doi.org/10.1080/19420862.2022.2076775openalex-snapshot

Deep mutational engineering of broadly-neutralizing nanobodies accommodating SARS-CoV-1 and 2 antigenic drift

inferred← citeshttps://doi.org/10.1080/19420862.2023.2285904openalex-snapshot

BERT2DAb: a pre-trained model for antibody representation based on amino acid sequences and 2D-structure

inferred← citeshttps://doi.org/10.1080/19420862.2026.2623330openalex-snapshot

ASD: antigen-specific antibody database

inferred← citeshttps://doi.org/10.1080/21645515.2025.2526873openalex-snapshot

Optimizing the breadth of SARS-CoV-2-neutralizing antibodies in vivo and in silico

inferred← citeshttps://doi.org/10.1080/22221751.2022.2030197openalex-snapshot

B cell receptor signatures associated with strong and poor SARS-CoV-2 vaccine responses

inferred← citeshttps://doi.org/10.1080/22221751.2022.2063074openalex-snapshot

The prominent role of a CDR1 somatic hypermutation for convergent IGHV3-53/3-66 antibodies in binding to SARS-CoV-2

inferred← citeshttps://doi.org/10.1080/22221751.2022.2140611openalex-snapshot

Shared IGHV1-69-encoded neutralizing antibodies contribute to the emergence of L452R substitution in SARS-CoV-2 variants

inferred← citeshttps://doi.org/10.1080/22221751.2024.2447615openalex-snapshot

Enhanced antibody response to the conformational non-RBD region via DNA prime-protein boost elicits broad cross-neutralization against SARS-CoV-2 variants

inferred← citeshttps://doi.org/10.1088/2632-2153/ae20ecopenalex-snapshot

NbBench: benchmarking language models for comprehensive nanobody tasks

inferred← citeshttps://doi.org/10.1093/abt/tbac011openalex-snapshot

Massively multiplexed affinity characterization of therapeutic antibodies against SARS-CoV-2 variants

inferred← citeshttps://doi.org/10.1093/abt/tbag039openalex-snapshot

Beyond affinity: AI-supported developability assessment and multi-objective optimization in antibody development

inferred← citeshttps://doi.org/10.1093/bib/bbaa328openalex-snapshot

A review of COVID-19 biomarkers and drug targets: resources and tools

inferred← citeshttps://doi.org/10.1093/bib/bbab241openalex-snapshot

Tracking the pipeline: immunoinformatics and the COVID-19 vaccine design

inferred← citeshttps://doi.org/10.1093/bib/bbab339openalex-snapshot

Recent omics-based computational methods for COVID-19 drug discovery and repurposing

inferred← citeshttps://doi.org/10.1093/bib/bbad191openalex-snapshot

SC-AIR-BERT: a pre-trained single-cell model for predicting the antigen-binding specificity of the adaptive immune receptor

inferred← citeshttps://doi.org/10.1093/bib/bbae183openalex-snapshot

CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses

inferred← citeshttps://doi.org/10.1093/bib/bbae307openalex-snapshot

Antibody design using deep learning: from sequence and structure design to affinity maturation

inferred← citeshttps://doi.org/10.1093/bib/bbae403openalex-snapshot

AntiFormer: graph enhanced large language model for binding affinity prediction

inferred← citeshttps://doi.org/10.1093/bib/bbaf008openalex-snapshot

AntiBinder: utilizing bidirectional attention and hybrid encoding for precise antibody–antigen interaction prediction

inferred← citeshttps://doi.org/10.1093/bib/bbaf238openalex-snapshot

RLEAAI: improving antibody–antigen interaction prediction using protein language model and sequence order information

inferred← citeshttps://doi.org/10.1093/bioadv/vbae170openalex-snapshot

Negative binomial mixture model for identification of noise in antibody-antigen specificity predictions from single-cell data

inferred← citeshttps://doi.org/10.1093/bioadv/vbaf328openalex-snapshot

CoV-UniBind: a unified antibody binding database for SARS-CoV-2

inferred← citeshttps://doi.org/10.1093/bioinformatics/btab660openalex-snapshot

DLAB: deep learning methods for structure-based virtual screening of antibodies

inferred← citeshttps://doi.org/10.1093/bioinformatics/btab694openalex-snapshot

COVID-19 Knowledge Graph from semantic integration of biomedical literature and databases

inferred← citeshttps://doi.org/10.1093/bioinformatics/btac439openalex-snapshot

Ab-CoV: a curated database for binding affinity and neutralization profiles of coronavirus-related antibodies

inferred← citeshttps://doi.org/10.1093/bioinformatics/btad196openalex-snapshot

Surface ID: a geometry-aware system for protein molecular surface comparison

inferred← citeshttps://doi.org/10.1093/database/baac112openalex-snapshot

Coronavirus Immunotherapeutic Consortium Database

showing the first 200 of 381

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