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Reimagining cholinergic therapy for Alzheimer’s disease

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inferredcites →https://doi.org/10.1001/archneur.1997.00550160091022openalex-snapshot

Effects of Xanomeline, a Selective Muscarinic Receptor Agonist, on Cognitive Function and Behavioral Symptoms in Alzheimer Disease

inferredcites →https://doi.org/10.1001/archneur.60.12.1745openalex-snapshot

Cortical Cholinergic Function Is More Severely Affected in Parkinsonian Dementia Than in Alzheimer Disease

inferredcites →https://doi.org/10.1001/jama.2014.3654openalex-snapshot

Pharmacological Treatment of Parkinson Disease

inferredcites →https://doi.org/10.1001/jama.2019.22360openalex-snapshot

Diagnosis and Treatment of Parkinson Disease

inferredcites →https://doi.org/10.1001/jamainternmed.2019.0677openalex-snapshot

Anticholinergic Drug Exposure and the Risk of Dementia

inferredcites →https://doi.org/10.1001/jamaneurol.2014.2757openalex-snapshot

Frequency of Cholinergic and Caudate Nucleus Dopaminergic Deficits Across the Predemented Cognitive Spectrum of Parkinson Disease and Evidence of Interaction Effects

inferredcites →https://doi.org/10.1001/jamaneurol.2015.1807openalex-snapshot

Nerve Growth Factor Gene Therapy

inferredcites →https://doi.org/10.1001/jamaneurol.2019.3606openalex-snapshot

Selective Vulnerability of the Nucleus Basalis of Meynert Among Neuropathologic Subtypes of Alzheimer Disease

inferredcites →https://doi.org/10.1002/(sici)1099-1166(199809)13:9<625::aid-gps835>3.0.co;2-2openalex-snapshot

Effect of gender and apolipoprotein E genotype on response to anticholinesterase therapy in Alzheimer's disease

inferredcites →https://doi.org/10.1002/14651858.cd001190.pub2openalex-snapshot

Donepezil for dementia due to Alzheimer's disease

inferredcites →https://doi.org/10.1002/14651858.cd006504.pub2openalex-snapshot

Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease

inferredcites →https://doi.org/10.1002/14651858.cd009132openalex-snapshot

Cholinesterase inhibitors for mild cognitive impairment

inferredcites →https://doi.org/10.1002/1531-8249(200009)48:3<391::aid-ana17>3.0.co;2-hopenalex-snapshot

Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex

inferredcites →https://doi.org/10.1002/1531-8249(200012)48:6<913::aid-ana12>3.0.co;2-sopenalex-snapshot

The selective muscarinic M1 agonist AF102B decreases levels of total A? in cerebrospinal fluid of patients with Alzheimer's disease

inferredcites →https://doi.org/10.1002/alz.12112openalex-snapshot

Further understanding the connection between Alzheimer's disease and Down syndrome

inferredcites →https://doi.org/10.1002/alz.12229openalex-snapshot

Nerve growth factor (NGF) pathway biomarkers in Down syndrome prior to and after the onset of clinical Alzheimer's disease: A paired CSF and plasma study

inferredcites →https://doi.org/10.1002/ana.10069openalex-snapshot

Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment

inferredcites →https://doi.org/10.1002/ana.10639openalex-snapshot

Increased Alzheimer pathology in Parkinson's disease related to antimuscarinic drugs

inferredcites →https://doi.org/10.1002/ana.20100openalex-snapshot

Cholinergic nucleus basalis tauopathy emerges early in the aging‐MCI‐AD continuum

inferredcites →https://doi.org/10.1002/ana.22105openalex-snapshot

Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease

inferredcites →https://doi.org/10.1002/ana.410100602openalex-snapshot

A unifying hypothesis for the cause of amyotrophic lateral sclerosis, parkinsonism, and alzheimer disease

inferredcites →https://doi.org/10.1002/ana.410170310openalex-snapshot

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome

inferredcites →https://doi.org/10.1002/ana.410270502openalex-snapshot

Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity

inferredcites →https://doi.org/10.1002/cne.23415openalex-snapshot

Cholinergic circuitry of the human nucleus basalis and its fate in Alzheimer's disease

inferredcites →https://doi.org/10.1002/cne.902750205openalex-snapshot

Nucleus basalis (Ch4) and cortical cholinergic innervation in the human brain: Observations based on the distribution of acetylcholinesterase and choline acetyltransferase

inferredcites →https://doi.org/10.1002/ddr.10085openalex-snapshot

Talsaclidine (WAL 2014 FU), a muscarinic M1 receptor agonist for the treatment of Alzheimer's disease

inferredcites →https://doi.org/10.1002/gps.1557openalex-snapshot

Effectiveness of acetylcholinesterase inhibitors: diagnosis and severity as predictors of response in routine practice

inferredcites →https://doi.org/10.1002/gps.2195openalex-snapshot

Can CSF biomarkers or pre‐treatment progression rate predict response to cholinesterase inhibitor treatment in Alzheimer's disease?

inferredcites →https://doi.org/10.1002/gps.4043openalex-snapshot

Sex and ESR1 genotype may influence the response to treatment with donepezil and rivastigmine in patients with Alzheimer's disease

inferredcites →https://doi.org/10.1002/gps.5522openalex-snapshot

Significant effects of cholinesterase inhibitors on tau pathology in the Alzheimer's disease continuum: An in vivo positron emission tomography study

inferredcites →https://doi.org/10.1002/j.1875-9114.1998.tb03877.xopenalex-snapshot

Metrifonate: Overview of Safety and Efficacy

inferredcites →https://doi.org/10.1002/jnr.23827openalex-snapshot

Sex and the development of Alzheimer's disease

inferredcites →https://doi.org/10.1002/syn.10310openalex-snapshot

Effects of acute acetylcholinesterase inhibition on the cerebral cholinergic neuronal system and cognitive function: Functional imaging of the conscious monkey brain using animal PET in combination with microdialysis

inferredcites →https://doi.org/10.1006/clim.2001.5128openalex-snapshot

Use of Muscarinic Agonists in the Treatment of Sjögren's Syndrome

inferredcites →https://doi.org/10.1006/exnr.1994.1148openalex-snapshot

Effects of Estrogen Replacement on the Relative Levels of Choline Acetyltransferase, trkA, and Nerve Growth Factor Messenger RNAs in the Basal Forebrain and Hippocampal Formation of Adult Rats

inferredcites →https://doi.org/10.1006/exnr.1997.6504openalex-snapshot

Reduction in p140-TrkA Receptor Protein within the Nucleus Basalis and Cortex in Alzheimer's Disease

inferredcites →https://doi.org/10.1006/mcne.2001.1016openalex-snapshot

The Precursor Pro-Nerve Growth Factor Is the Predominant Form of Nerve Growth Factor in Brain and Is Increased in Alzheimer's Disease

inferredcites →https://doi.org/10.1007/978-3-0348-7218-8_24openalex-snapshot

The Pharmacology of Neurotrophic Factors

inferredcites →https://doi.org/10.1007/978-3-642-45106-5_7openalex-snapshot

Sortilins in Neurotrophic Factor Signaling

inferredcites →https://doi.org/10.1007/978-3-7091-6139-5_17openalex-snapshot

Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer’ disease

inferredcites →https://doi.org/10.1007/bf02244644openalex-snapshot

Further analysis of the cognitive effects of tetrahydroaminoacridine (THA) in Alzheimer's disease: assessment of attentional and mnemonic function using CANTAB

inferredcites →https://doi.org/10.1007/bf02257624openalex-snapshot

Nerve growth factor affects11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (Case Report)

inferredcites →https://doi.org/10.1007/s00228-013-1483-yopenalex-snapshot

A population-based study of dosing and persistence with anti-dementia medications

inferredcites →https://doi.org/10.1007/s004019900178openalex-snapshot

Evolution of Alzheimer's disease-related cytoskeletal changes in the basal nucleus of Meynert

inferredcites →https://doi.org/10.1007/s00415-009-5000-2openalex-snapshot

Cholinesterase inhibitors may increase phosphorylated tau in Alzheimer’s disease

inferredcites →https://doi.org/10.1007/s00702-015-1462-9openalex-snapshot

The rationale for deep brain stimulation in Alzheimer’s disease

inferredcites →https://doi.org/10.1007/s00702-017-1775-yopenalex-snapshot

Cortical afferent inhibition abnormalities reveal cholinergic dysfunction in Parkinson’s disease: a reappraisal

inferredcites →https://doi.org/10.1007/s007020070034openalex-snapshot

Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3β inhibition and in neurons

inferredcites →https://doi.org/10.1007/s007020200090openalex-snapshot

Effect of subchronic administration of metrifonate, rivastigmine and donepezil on brain acetylcholine in aged F344 rats

inferredcites →https://doi.org/10.1007/s100720200086openalex-snapshot

Cerebrospinal fluid levels of biomarkers and activity of acetylcholinesterase (AChE) and butyrylcholinesterase in AD patients before and after treatment with different AChE inhibitors

inferredcites →https://doi.org/10.1007/s11064-006-9270-0openalex-snapshot

The Failure in NGF Maturation and its Increased Degradation as the Probable Cause for the Vulnerability of Cholinergic Neurons in Alzheimer’s Disease

inferredcites →https://doi.org/10.1007/s11910-010-0122-6openalex-snapshot

Hormonal Influences on Cognition and Risk for Alzheimer’s Disease

inferredcites →https://doi.org/10.1007/s12031-002-0025-3openalex-snapshot

AF150(S) and AF267B

inferredcites →https://doi.org/10.1007/s12031-009-9238-zopenalex-snapshot

Cholinergic Involvement in Alzheimer’s Disease. A Link with NGF Maturation and Degradation

inferredcites →https://doi.org/10.1007/s12035-020-02009-xopenalex-snapshot

Chronic Administration of Scopolamine Increased GSK3βP9, Beta Secretase, Amyloid Beta, and Oxidative Stress in the Hippocampus of Wistar Rats

inferredcites →https://doi.org/10.1007/s40264-014-0161-zopenalex-snapshot

Cardiovascular Effects of Drugs Used to Treat Alzheimer’s Disease

inferredcites →https://doi.org/10.1007/s40266-015-0273-xopenalex-snapshot

The Use of Cholinesterase Inhibitors Across All Stages of Alzheimer’s Disease

inferredcites →https://doi.org/10.1007/s40266-018-00636-7openalex-snapshot

Pharmacological Management of Dementia with Lewy Bodies

inferredcites →https://doi.org/10.1007/s40266-021-00851-9openalex-snapshot

Antipsychotic Initiation Among Older Dementia Patients Using Cholinesterase Inhibitors: A National Retrospective Cohort Study

inferredcites →https://doi.org/10.1016/0006-3223(93)90044-eopenalex-snapshot

Loss of striatal cholinergic neurons as a basis for tardive and L-dopa-induced dyskinesias, neuroleptic-induced supersensitivity psychosis and refractory schizophrenia

inferredcites →https://doi.org/10.1016/0028-3908(93)90114-iopenalex-snapshot

Cholinesterase inhibitor effects on extracellular acetylcholine in rat striatum

inferredcites →https://doi.org/10.1016/0166-2236(91)90061-xopenalex-snapshot

The basal forebrain-cortical cholinergic system: interpreting the functional consequences of excitotoxic lesions

inferredcites →https://doi.org/10.1016/0169-328x(86)90023-9openalex-snapshot

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease

inferredcites →https://doi.org/10.1016/0169-328x(94)90159-7openalex-snapshot

NGF mRNA is not decreased in frontal cortex from Alzheimer's Disease patients

inferredcites →https://doi.org/10.1016/0197-4580(90)90059-9openalex-snapshot

Quantitative assessment of cortical synaptic density in Alzheimer's disease

inferredcites →https://doi.org/10.1016/0301-0082(95)00013-lopenalex-snapshot

The pedunculopontine tegmental nucleus: Where the striatum meets the reticular formation

inferredcites →https://doi.org/10.1016/0304-3940(83)90171-4openalex-snapshot

Loss of pigmented dopamine-β-hydroxylase positive cells from locus coeruleus in senile dementia of alzheimer's type

inferredcites →https://doi.org/10.1016/0304-3940(86)90629-4openalex-snapshot

Reduced number of [3H]nicotine and [3H]acetylcholine binding sites in the frontal cortex of Alzheimer brains

inferredcites →https://doi.org/10.1016/0304-3940(95)12256-7openalex-snapshot

Monoaminergic neurotransmitters, their precursors and metabolites in brains of Alzheimer patients

inferredcites →https://doi.org/10.1016/0306-4522(94)90285-2openalex-snapshot

Expression of neurotrophin and trk receptor genes in adult rats with fimbria transections: Effect of intraventricular nerve growth factor and brain-derived neurotrophic factor administration

inferredcites →https://doi.org/10.1016/0306-4522(95)91510-jopenalex-snapshot

Differential expression of p140trk, p75NGFR and growth-associated phosphoprotein-43 genes in nucleus basalis magnocellularis, thalamus and adjacent cortex following neocortical infarction and nerve growth factor treatment

inferredcites →https://doi.org/10.1016/0361-9230(91)90038-lopenalex-snapshot

Muscarinic cholinoceptive neurons in the frontal cortex in Alzheimer's disease

inferredcites →https://doi.org/10.1016/0893-6080(94)90053-1openalex-snapshot

Runaway synaptic modification in models of cortex: Implications for Alzheimer's disease

inferredcites →https://doi.org/10.1016/bs.apha.2019.12.003openalex-snapshot

M1 muscarinic acetylcholine receptors: A therapeutic strategy for symptomatic and disease-modifying effects in Alzheimer's disease?

inferredcites →https://doi.org/10.1016/j.ajpath.2011.04.041openalex-snapshot

Loss of Muscarinic M1 Receptor Exacerbates Alzheimer's Disease–Like Pathology and Cognitive Decline

inferredcites →https://doi.org/10.1016/j.amjopharm.2006.09.009openalex-snapshot

Sex influences on cholinesterase inhibitor treatment in elderly individuals with alzheimer's disease

inferredcites →https://doi.org/10.1016/j.biopsych.2011.06.019openalex-snapshot

Atrophy of the Cholinergic Basal Forebrain Over the Adult Age Range and in Early Stages of Alzheimer's Disease

inferredcites →https://doi.org/10.1016/j.cbi.2010.04.002openalex-snapshot

Gender-related differences in circadian rhythm of rat plasma acetyl- and butyrylcholinesterase: Effects of sex hormone withdrawal

inferredcites →https://doi.org/10.1016/j.cbi.2012.09.016openalex-snapshot

Effect of cholinesterase inhibitors on attention

inferredcites →https://doi.org/10.1016/j.celrep.2018.06.001openalex-snapshot

Longitudinal Alzheimer’s Degeneration Reflects the Spatial Topography of Cholinergic Basal Forebrain Projections

inferredcites →https://doi.org/10.1016/j.conb.2006.09.002openalex-snapshot

The role of acetylcholine in learning and memory

inferredcites →https://doi.org/10.1016/j.cub.2017.07.021openalex-snapshot

Intermittent Stimulation of the Nucleus Basalis of Meynert Improves Working Memory in Adult Monkeys

inferredcites →https://doi.org/10.1016/j.drudis.2019.08.009openalex-snapshot

Cholinergic muscarinic M1 and M4 receptors as therapeutic targets for cognitive, behavioural, and psychological symptoms in psychiatric and neurological disorders

inferredcites →https://doi.org/10.1016/j.jalz.2011.02.009openalex-snapshot

Long‐term progression of Alzheimer's disease in patients under antidementia drugs

inferredcites →https://doi.org/10.1016/j.jalz.2014.10.003openalex-snapshot

Donepezil decreases annual rate of hippocampal atrophy in suspected prodromal Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.jalz.2014.11.008openalex-snapshot

Changes in CSF cholinergic biomarkers in response to cell therapy with NGF in patients with Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.jalz.2016.05.001openalex-snapshot

An inflammatory and trophic disconnect biomarker profile revealed in Down syndrome plasma: Relation to cognitive decline and longitudinal evaluation

inferredcites →https://doi.org/10.1016/j.jalz.2017.11.009openalex-snapshot

AF710B, an M1/sigma‐1 receptor agonist with long‐lasting disease‐modifying properties in a transgenic rat model of Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.jchemneu.2010.03.005openalex-snapshot

Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.jns.2017.03.049openalex-snapshot

Impaired cholinergic transmission in patients with Parkinson's disease and olfactory dysfunction

inferredcites →https://doi.org/10.1016/j.mcn.2008.07.013openalex-snapshot

Isoform-specific contribution of protein kinase C to prion processing

inferredcites →https://doi.org/10.1016/j.mcn.2011.04.008openalex-snapshot

ERK1-independent α-secretase cut of β-amyloid precursor protein via M1 muscarinic receptors and PKCα/ε

inferredcites →https://doi.org/10.1016/j.nbd.2004.07.016openalex-snapshot

M1 muscarinic receptor activation protects neurons from β-amyloid toxicity. A role for Wnt signaling pathway

inferredcites →https://doi.org/10.1016/j.nbd.2017.08.019openalex-snapshot

Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2007.02.020openalex-snapshot

PET imaging of the in vivo brain acetylcholinesterase activity and nicotine binding in galantamine-treated patients with AD

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2010.11.015openalex-snapshot

Volumetric analysis of the substantia innominata in patients with Parkinson's disease according to cognitive status

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2013.05.020openalex-snapshot

Cholinergic activity correlates with reserve proxies in Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2018.01.025openalex-snapshot

Reduced substantia innominata volume mediates contributions of microvascular and macrovascular disease to cognitive deficits in Alzheimer's disease

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2018.03.002openalex-snapshot

Compromise of cortical proNGF maturation causes selective retrograde atrophy in cholinergic nucleus basalis neurons

inferredcites →https://doi.org/10.1016/j.neurobiolaging.2019.11.013openalex-snapshot

Basal forebrain metabolism in Alzheimer's disease continuum: relationship with education

inferredcites →https://doi.org/10.1016/j.neuroimage.2006.02.015openalex-snapshot

Donepezil effects on sources of cortical rhythms in mild Alzheimer's disease: Responders vs. Non-Responders

inferredcites →https://doi.org/10.1016/j.neuron.2006.01.020openalex-snapshot

M1 Receptors Play a Central Role in Modulating AD-like Pathology in Transgenic Mice

inferredcites →https://doi.org/10.1016/j.neuron.2006.05.022openalex-snapshot

Increased App Expression in a Mouse Model of Down's Syndrome Disrupts NGF Transport and Causes Cholinergic Neuron Degeneration

inferredcites →https://doi.org/10.1016/j.neuron.2016.09.006openalex-snapshot

Basal Forebrain Cholinergic Circuits and Signaling in Cognition and Cognitive Decline

inferredcites →https://doi.org/10.1016/j.neuron.2018.05.027openalex-snapshot

Muscarinic M1 Receptor Overstimulation Disrupts Working Memory Activity for Rules in Primate Prefrontal Cortex

inferredcites →https://doi.org/10.1016/j.neuropharm.2018.01.028openalex-snapshot

Current status of muscarinic M1 and M4 receptors as drug targets for neurodegenerative diseases

inferredcites →https://doi.org/10.1016/j.neuropharm.2019.107860openalex-snapshot

Modifying the progression of Alzheimer's and Parkinson's disease with deep brain stimulation

inferredcites →https://doi.org/10.1016/j.neuropharm.2020.108081openalex-snapshot

Future avenues for Alzheimer's disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery

inferredcites →https://doi.org/10.1016/j.neuropharm.2021.108489openalex-snapshot

Aged rhesus monkeys: Cognitive performance categorizations and preclinical drug testing

inferredcites →https://doi.org/10.1016/j.neuroscience.2015.03.006openalex-snapshot

Hippocampal plasticity during the progression of Alzheimer’s disease

inferredcites →https://doi.org/10.1016/j.nurt.2008.05.002openalex-snapshot

Cholinergic Treatments with Emphasis on M1 Muscarinic Agonists as Potential Disease-Modifying Agents for Alzheimer's Disease

inferredcites →https://doi.org/10.1016/j.phrs.2010.02.009openalex-snapshot

Acetylcholinesterase inhibitors and memantine for neuroenhancement in healthy individuals: A systematic review

inferredcites →https://doi.org/10.1016/j.phrs.2016.11.035openalex-snapshot

Sex and gender differences in the treatment of Alzheimer’s disease: A systematic review of randomized controlled trials

inferredcites →https://doi.org/10.1016/j.tips.2014.04.010openalex-snapshot

Nerve growth factor metabolic dysfunction in Alzheimer's disease and Down syndrome

inferredcites →https://doi.org/10.1016/j.trci.2018.03.004openalex-snapshot

Randomized, controlled, proof‐of‐concept trial of MK‐7622 in Alzheimer's disease

inferredcites →https://doi.org/10.1016/s0002-9440(10)62275-4openalex-snapshot

Pro-NGF Isolated from the Human Brain Affected by Alzheimer's Disease Induces Neuronal Apoptosis Mediated by p75NTR

inferredcites →https://doi.org/10.1016/s0006-8993(01)02484-2openalex-snapshot

Reduction of cerebrospinal fluid amyloid β after systemic administration of M1 muscarinic agonists

inferredcites →https://doi.org/10.1016/s0014-2999(00)00093-5openalex-snapshot

Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease

inferredcites →https://doi.org/10.1016/s0028-3908(02)00378-7openalex-snapshot

Sex dimorphisms in the cognitive-enhancing action of the Alzheimer’s drug donepezil in aged Rhesus monkeys

inferredcites →https://doi.org/10.1016/s0028-3908(99)00157-4openalex-snapshot

Gender differences in the effect of rivastigmine on brain cholinesterase activity and cognitive function in rats

inferredcites →https://doi.org/10.1016/s0079-6123(03)45003-6openalex-snapshot

Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus

inferredcites →https://doi.org/10.1016/s0079-6123(08)62114-7openalex-snapshot

Chapter 30 New trends in cholinergic therapy for Alzheimer disease: nicotinic agonists or cholinesterase inhibitors?

inferredcites →https://doi.org/10.1016/s0079-6123(08)62408-5openalex-snapshot

Chapter 32: Trophic responses of forebrain cholinergic neurons: a discussion

inferredcites →https://doi.org/10.1016/s0140-6736(06)68350-5openalex-snapshot

Donepezil in patients with severe Alzheimer's disease: double-blind, parallel-group, placebo-controlled study

inferredcites →https://doi.org/10.1016/s0140-6736(20)30689-9openalex-snapshot

Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study

inferredcites →https://doi.org/10.1016/s0140-6736(76)91936-xopenalex-snapshot

SELECTIVE LOSS OF CENTRAL CHOLINERGIC NEURONS IN ALZHEIMER'S DISEASE

inferredcites →https://doi.org/10.1016/s0140-6736(80)92137-6openalex-snapshot

ALZHEIMER-LIKE CHOLINERGIC DEFICIENCY IN DOWN SYNDROME

inferredcites →https://doi.org/10.1016/s0166-2236(84)80161-7openalex-snapshot

The anatomy of the CNS cholinergic neurons

inferredcites →https://doi.org/10.1016/s0169-328x(96)00193-3openalex-snapshot

Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex

inferredcites →https://doi.org/10.1016/s0197-4580(00)83323-0openalex-snapshot

The effects of rivastigmine on behavioral symptoms in severe ad patients in a nursing home setting

inferredcites →https://doi.org/10.1016/s0304-3940(98)00019-6openalex-snapshot

Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease

inferredcites →https://doi.org/10.1016/s0361-9230(99)00219-1openalex-snapshot

Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans

inferredcites →https://doi.org/10.1016/s0896-6273(04)00145-xopenalex-snapshot

Effects of Cholinergic Enhancement on Visual Stimulation, Spatial Attention, and Spatial Working Memory

inferredcites →https://doi.org/10.1016/s1474-4422(07)70109-6openalex-snapshot

Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study

inferredcites →https://doi.org/10.1016/s1474-4422(07)70113-8openalex-snapshot

MCI treatment trials: failure or not?

inferredcites →https://doi.org/10.1016/s1474-4422(15)00258-6openalex-snapshot

Nursing home placement in the Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD) trial: secondary and post-hoc analyses

inferredcites →https://doi.org/10.1016/s1474-4422(15)00389-0openalex-snapshot

Rivastigmine for gait stability in patients with Parkinson's disease (ReSPonD): a randomised, double-blind, placebo-controlled, phase 2 trial

inferredcites →https://doi.org/10.1016/s1569-7339(08)00237-3openalex-snapshot

Handbook Of Behavioral Neuroscience

inferredcites →https://doi.org/10.1017/s1092852900020174openalex-snapshot

Selective Benefit of Donepezil on Oral Naming in Alzheimer's Disease in Men Compared to Women

inferredcites →https://doi.org/10.1021/acs.jmedchem.7b00597openalex-snapshot

Design and Synthesis of γ- and δ-Lactam M 1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M 1 -Selective PAM with Weak Agonist Activity

inferredcites →https://doi.org/10.1021/acschemneuro.6b00278openalex-snapshot

Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer’s Disease Mouse Model

inferredcites →https://doi.org/10.1038/177185a0openalex-snapshot

Quantitative Determination of Acetylcholinesterase Activity in Individual Nerve Cells

inferredcites →https://doi.org/10.1038/4571090aopenalex-snapshot

A prion protein connection

inferredcites →https://doi.org/10.1038/mp.2017.183openalex-snapshot

Quantification of brain cholinergic denervation in Alzheimer’s disease using PET imaging with [18F]-FEOBV

inferredcites →https://doi.org/10.1038/nature07761openalex-snapshot

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

inferredcites →https://doi.org/10.1038/ncomms13249openalex-snapshot

Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

inferredcites →https://doi.org/10.1038/nrneurol.2013.223openalex-snapshot

Alzheimer disease therapy—moving from amyloid-β to tau

inferredcites →https://doi.org/10.1038/s41380-020-0797-2openalex-snapshot

The human brain NGF metabolic pathway is impaired in the pre-clinical and clinical continuum of Alzheimers disease

inferredcites →https://doi.org/10.1038/s41386-018-0033-9openalex-snapshot

M1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition

inferredcites →https://doi.org/10.1038/s41401-020-00565-5openalex-snapshot

New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer’s disease

inferredcites →https://doi.org/10.1038/s41582-018-0032-9openalex-snapshot

Sex differences in Alzheimer disease — the gateway to precision medicine

inferredcites →https://doi.org/10.1038/s41582-018-0132-6openalex-snapshot

Dementia in Down syndrome: unique insights for Alzheimer disease research

inferredcites →https://doi.org/10.1038/s41598-017-09780-3openalex-snapshot

Reduced basal forebrain atrophy progression in a randomized Donepezil trial in prodromal Alzheimer’s disease

inferredcites →https://doi.org/10.1038/sj.cdd.4400713openalex-snapshot

M1 muscarinic receptors block caspase activation by phosphoinositide 3-kinase- and MAPK/ERK-independent pathways

inferredcites →https://doi.org/10.1038/srep29266openalex-snapshot

Association between acetylcholinesterase inhibitors and risk of stroke in patients with dementia

inferredcites →https://doi.org/10.1042/bj0262056openalex-snapshot

Choline-esterase. An enzyme present in the blood-serum of the horse

inferredcites →https://doi.org/10.1046/j.1365-2125.1998.0460s1007.xopenalex-snapshot

Pharmacokinetic and pharmacodynamic profile of donepezil HCl following multiple oral doses

inferredcites →https://doi.org/10.1046/j.1471-4159.1996.66020877.xopenalex-snapshot

Activation of m 1 Muscarinic Acetylcholine Receptor Regulates τ Phosphorylation in Transfected PC12 Cells

inferredcites →https://doi.org/10.1046/j.1471-4159.1998.70051991.xopenalex-snapshot

M1 Muscarinic Agonist Treatment Reverses Cognitive and Cholinergic Impairments of Apolipoprotein E‐Deficient Mice

inferredcites →https://doi.org/10.1046/j.1471-4159.1998.71052094.xopenalex-snapshot

Mitogen‐Activated Protein Kinase‐Dependent and Protein Kinase C‐Dependent Pathways Link the m1 Muscarinic Receptor to β‐Amyloid Precursor Protein Secretion

inferredcites →https://doi.org/10.1046/j.1471-4159.1999.0720206.xopenalex-snapshot

Site‐Specific Dephosphorylation of Tau of Apolipoprotein E‐Deficient and Control Mice by M1 Muscarinic Agonist Treatment

inferredcites →https://doi.org/10.1046/j.1471-4159.2000.740777.xopenalex-snapshot

Increased Levels of Tau Protein in SH‐SY5Y Cells After Treatment with Cholinesterase Inhibitors and Nicotinic Agonists

inferredcites →https://doi.org/10.1055/s-0031-1296432openalex-snapshot

Gender Differences in the Pharmacokinetics of Rivastigmine in Rats

inferredcites →https://doi.org/10.1055/s-0031-1296941openalex-snapshot

Pharmacokinetics and Tissue Distribution of Galantamine and Galantamine-related Radioactivity after Single Intravenous and Oral Administration in the Rat

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Parkinson's Disease Dementia and Lewy Body Disease

inferredcites →https://doi.org/10.1055/s-2007-1014631openalex-snapshot

Neuronotrophic Factors in Cellular Functional and Cognitive Repair of Adult Brain

inferredcites →https://doi.org/10.1056/nejm198611133152001openalex-snapshot

Oral Tetrahydroaminoacridine in Long-Term Treatment of Senile Dementia, Alzheimer Type

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Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment

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Muscarinic Cholinergic Receptor Agonist and Peripheral Antagonist for Schizophrenia

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Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease

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Activity-dependent release of precursor nerve growth factor, conversion to mature nerve growth factor, and its degradation by a protease cascade

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Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion

inferredcites →https://doi.org/10.1073/pnas.93.24.13541openalex-snapshot

Muscarinic acetylcholine receptor expression in memory circuits: Implications for treatment of Alzheimer disease

inferredcites →https://doi.org/10.1073/pnas.95.19.11465openalex-snapshot

Activation of the genetically defined m1 muscarinic receptor potentiates N -methyl- d -aspartate (NMDA) receptor currents in hippocampal pyramidal cells

inferredcites →https://doi.org/10.1073/pnas.96.7.4067openalex-snapshot

A nerve growth factor mimetic TrkA antagonist causes withdrawal of cortical cholinergic boutons in the adult rat

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Identification of diverse nerve growth factor-regulated genes by serial analysis of gene expression (SAGE) profiling

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The α-Secretase-derived N-terminal Product of Cellular Prion, N1, Displays Neuroprotective Function in Vitro and in Vivo

inferredcites →https://doi.org/10.1074/jbc.m209892200openalex-snapshot

Activation of Muscarinic Receptors Inhibits औ-Amyloid Peptide-induced Signaling in Cortical Slices

inferredcites →https://doi.org/10.1074/jbc.m212532200openalex-snapshot

α7 Nicotinic Acetylcholine Receptors Mediate β-Amyloid Peptide-induced Tau Protein Phosphorylation

inferredcites →https://doi.org/10.1080/19420889.2017.1389359openalex-snapshot

Potential for intermittent stimulation of nucleus basalis of Meynert to impact treatment of alzheimer's disease

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NEUROTRANSMITTER-RELATED ENZYMES AND INDICES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES

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The role of noradrenaline in cognition and cognitive disorders

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The cognitive ability of an incident cohort of Parkinson’s patients in the UK. The CamPaIGN study

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Modulation of fusiform cortex activity by cholinesterase inhibition predicts effects on subsequent memory

inferredcites →https://doi.org/10.1093/brain/awt372openalex-snapshot

RETRACTED AND REPLACED: Nerve growth factor metabolic dysfunction in Down’s syndrome brains

inferredcites →https://doi.org/10.1093/brain/awx310openalex-snapshot

In vivo cholinergic basal forebrain atrophy predicts cognitive decline in de novo Parkinson’s disease

inferredcites →https://doi.org/10.1093/brain/awx333openalex-snapshot

Early nucleus basalis of Meynert degeneration predicts cognitive decline in Parkinson’s disease

inferredcites →https://doi.org/10.1093/brain/awx356openalex-snapshot

Effect of cholinergic treatment depends on cholinergic integrity in early Alzheimer’s disease

inferredcites →https://doi.org/10.1093/brain/awy072openalex-snapshot

Nucleus basalis of Meynert degeneration precedes and predicts cognitive impairment in Parkinson’s disease

inferredcites →https://doi.org/10.1093/brain/awy132openalex-snapshot

The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease

inferredcites →https://doi.org/10.1093/braincomms/fcaa058openalex-snapshot

M1 muscarinic acetylcholine receptor dysfunction in moderate Alzheimer’s disease pathology

inferredcites →https://doi.org/10.1093/cercor/bhv227openalex-snapshot

Activation of Muscarinic M1 Acetylcholine Receptors Induces Long-Term Potentiation in the Hippocampus

inferredcites →https://doi.org/10.1093/cercor/bhw177openalex-snapshot

Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology

inferredcites →https://doi.org/10.1093/cercor/bhw195openalex-snapshot

Volume Loss of the Nucleus Basalis of Meynert is Associated with Atrophy of Innervated Regions in Mild Cognitive Impairment

inferredcites →https://doi.org/10.1093/eurheartj/eht182openalex-snapshot

The use of cholinesterase inhibitors and the risk of myocardial infarction and death: a nationwide cohort study in subjects with Alzheimer's disease

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Prevalence and Impact of Medical Comorbidity in Alzheimer's Disease

inferredcites →https://doi.org/10.1093/jnen/59.4.308openalex-snapshot

The Cholinergic Deficit Coincides with Aβ Deposition at the Earliest Histopathologic Stages of Alzheimer Disease

inferredcites →https://doi.org/10.1093/jnen/63.6.641openalex-snapshot

Increased proNGF Levels in Subjects with Mild Cognitive Impairment and Mild Alzheimer Disease

inferredcites →https://doi.org/10.1093/ntr/nty116openalex-snapshot

Nicotinic Acetylcholine Receptor Agonists for the Treatment of Alzheimer’s Dementia: An Update

inferredcites →https://doi.org/10.1093/sleep/32.8.999openalex-snapshot

Donepezil Improves Episodic Memory in Young Individuals Vulnerable to the Effects of Sleep Deprivation

showing the first 200 of 315

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Carltonine-Derived Compounds for Targeted Butyrylcholinesterase Inhibition

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Innovative Test Strip‐Based Colorimetric Sensors Integrated With Affinity Chromatography: Acetylcholinesterase Inhibitor Screening Breakthrough in Lycium Barbarum Leaves

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Sex‐specific declines in cholinergic‐targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease

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Sex‐dependent cholinergic effects on amyloid pathology: A translational study

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Evidence for a novel neuronal mechanism driving Alzheimer's disease, upstream of amyloid

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The impact of cholinesterase inhibitors on cognitive trajectories in mild cognitive impairment patients based on amyloid beta status

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Single‐nucleus analysis reveals oxidative stress in Down syndrome basal forebrain neurons at birth

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New Peripheral Pyridine‐Substituted Cobalt, Copper, and Manganese Phthalocyanines as Potential In Vitro Acetyl/Butyrylcholinesterase Inhibitors in the Treatment of Alzheimer's Disease

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Serotonergic Modulators in Alzheimer's Disease: A Hope in the Hopeless Condition

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Advances in Targeting Central Cholinergic Dysfunction for Neurodegenerative Diseases: From Pharmacotherapy to Neuromodulation

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Amyloid accumulation, brain atrophy, and cognitive decline in emergent Alzheimer's disease

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Cholinergic and behavior‐dependent beta and gamma waves are coupled between olfactory bulb and hippocampus

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Rapid identification of chemical components and screening of acetylcholinesterase inhibitors from Dalbergia odorifera based on mass defect and diagnostic ion filtering strategy, affinity ultrafiltration, and liquid chromatography‐tandem mass spectrometry

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Multi‐Target Drug Design in Alzheimer's Disease Treatment: Emerging Technologies, Advantages, Challenges, and Limitations

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Role of Pyrazole Moiety in the Treatment of Alzheimer's Disease: A Comprehensive Review of Various Synthetic Routes and Probable Mechanisms of Action

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Recent Progress in the Treatment Strategies for Alzheimer’s Disease

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Management of Alzheimer’s Disease-Associated Cognitive Disabilities

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Novel diazepine-carbamate derivatives as dual-acting butyrylcholinesterase inhibitors and antioxidants for Alzheimer’s disease

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The Janus face of CaMKII: from memory consolidation to neurotoxic switch in Alzheimer’s disease

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Nanozyme-based dual-signal sensing system for colorimetric and photothermal detection of AChE activity in the blood of liver-injured mice

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Cholinergic neurotransmission in the brain of streptozotocin-induced rat model of sporadic Alzheimer’s disease: long-term follow up

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Botany, phytochemistry, pharmacology, phytotoxicity and industrial applications of Grewia tiliifolia Vahl: a comprehensive review

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Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase

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α-Synuclein as a molecular link between Parkinson’s disease and chronic kidney disease: insights into the kidney-brain axis

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Computational discovery and dynamic profiling of dual acetylcholinesterase and monoacylglycerol lipase inhibitors for Alzheimer’s disease

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Mechanisms of the Pathogenesis of Alzheimer’s Disease: The Role of the Basal Forebrain

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Synergistic Neuroprotection in Tauopathic Mice via Green-Synthesized Silver Nanoparticles Co-delivering Methylene Blue and Moringa oleifera

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Environmental Factors Drive Neurodegenerative Diseases Through Glutamate Excitotoxicity: A Convergent Mechanistic Pathway

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Lipid metabolism, neuroinflammation, and oxidative stress in Alzheimer disease: an integrated mechanistic review

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Turning the Spotlight to Cholinergic Pharmacotherapy of the Human Language System

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Analysis of the mitochondrial status of murine neuronal N2a cells treated with resveratrol and synthetic isomeric resveratrol analogs: aza-stilbenes

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Why do we need new therapies for neurodegenerative disorders?

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The involvement of the cholinergic system in Alzheimer disease

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NGF-based cholinergic therapies in Alzheimer disease

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A brief history of the CNS cholinergic transmission

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Cognition and modulation of the cholinergic system

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Memory network and cognitive reserve are associated with preserved and stimulated cholinergic neurotransmission

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Cholinergic therapy in Alzheimer disease

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CNS muscarinic receptors and muscarinic receptor agonists in Alzheimer disease treatment

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Discovery of novel butyrylcholinesterase inhibitors for treating Alzheimer's disease

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β-Sitosterol ameliorates the cognitive deficits and neuropathological hallmarks in an Alzheimer’s disease model

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Determinants of approved acetylcholinesterase inhibitor response outcomes in Alzheimer’s disease: relevance for precision medicine in neurodegenerative diseases

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Structural and functional remodeling of neural networks in β-amyloid driven hippocampal hyperactivity

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The new perspective of Alzheimer's Disease Research: Mechanism and therapeutic strategy of neuronal senescence

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Design, synthesis, and biological evaluation of novel capsaicin-tacrine hybrids as multi-target agents for the treatment of Alzheimer's disease

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Development of novel aza-stilbenes as a new class of selective MAO-B inhibitors for the treatment of Parkinson’s disease

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Carltonine B derivatives: Synthesis and structure-activity relationship insights for selective butyrylcholinesterase inhibition

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Neuroprotective effects of Anshen Bunao Syrup on cognitive dysfunction in Alzheimer's disease rat models

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Triple-mode sensing platform for acetylcholinesterase activity monitoring and anti-Alzheimer's drug screening based on a highly stable Cu (I) compound

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Solvents and detergents compatible with enzyme kinetic studies of cholinesterases

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Photochemistry-driven design of small molecule cholinesterase ligands

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Artificial intelligence-driven development of natural multi-target derivatives with BuChE inhibitory activity for treating Alzheimer's disease

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Emulsion-enhanced synergy of walnut-derived hexapeptide (EPEVLR) and DHA in mitigating D-galactose-induced cognitive decline in mice

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Interactions of memantine and rivastigmine with graphene oxide nanocarrier and beta-amyloid protein using molecular docking and in-silico methods

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Exploring the potential of probiotics in Alzheimer's disease and gut dysbiosis

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Testing effects of paced breathing on plasma Aβ and brain perivascular spaces

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Network pharmacology-guided identification and molecular validation of multi-target phytoconstituents from Gmelina arborea against Alzheimer’s disease

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Dihuang Yinzi improves scopolamine-induced learning and memory impairment by regulating plasma exosome-derived BDNF

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Structure−activity relationship of ginsenoside derivatives with different glycosides and double bond position on anti-aging bioactivities

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Insights into prevention mechanisms of bioactive components from healthy diets against Alzheimer's disease

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AChE/BuChE inhibitory, DNA nuclease and cytotoxic properties of axially 5-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl]pentanoxy and 5-[6-(hexyloxy)-2H-1,3-benzoxazin-3(4H)-yl]pentanoxy substituted silicon phthalocyanines

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Imidazopyridine–coumarin derivatives as novel multi-target directed ligands (MTDLs): Balancing acetylcholinesterase inhibition and antioxidant activity for neuroprotection

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Cyclic β-hairpin peptide loaded PLGA nanoparticles: A potential anti-amyloid therapeutic

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Adrenergic regulation of astroglial aerobic glycolysis and lipid metabolism: Towards a noradrenergic hypothesis of neurodegeneration

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Demencias. ¿Qué hacemos hoy y qué podríamos hacer? Análisis de una cohorte en el mundo real de pacientes con trastornos cognitivos y conductuales

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Noradrenergic and cholinergic systems take centre stage in neuropsychiatric diseases of ageing

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Rethinking early Alzheimer’s disease: An impaired internal model updating disorder?

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Early treatment with an M1 and sigma-1 receptor agonist prevents cognitive decline in a transgenic rat model displaying Alzheimer-like amyloid pathology

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Long-term nucleus basalis cholinergic lesions alter the structure of cortical vasculature, astrocytic density and microglial activity in Wistar rats

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Cell-type-specific optogenetic fMRI on basal forebrain reveals functional network basis of behavioral preference

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Action of the Purinergic and Cholinergic Anti-inflammatory Pathways on Oxidative Stress in Patients with Alzheimer’s Disease in the Context of the COVID-19 Pandemic

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Comparison of the efficacy of updated drugs for the treatment on the improvement of cognitive function in patients with Alzheimer ’s disease: A systematic review and network meta- analysis

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Early functional disconnection of the basal forebrain–hippocampal system predicts memory impairment in amnestic mild cognitive impairment

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Dissociating the involvement of muscarinic and nicotinic cholinergic receptors in object memory destabilization and reconsolidation

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Dual inhibition of butyrylcholinesterase and p38α mitogen-activated protein kinase: A new approach for the treatment of Alzheimer's disease

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Neochlorogenic acid ameliorates Alzheimer's disease-like pathology via scavenging oxidative stress and restoring blood-brain barrier function in zebrafish

inferred← citeshttps://doi.org/10.1016/j.psc.2022.07.003openalex-snapshot

Pathophysiology of Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1016/j.snb.2025.138511openalex-snapshot

Simultaneous profiling of cholinesterases and NAD(P)H in murine hippocampus via a dual-responsive indicator to investigate cholinergic impairment in Alzheimer's disease

inferred← citeshttps://doi.org/10.1016/j.talanta.2025.128086openalex-snapshot

Rapid and simple sensing of acetylcholinesterase and inhibition activity by utilizing a portable Raman spectrometer

inferred← citeshttps://doi.org/10.1016/j.trac.2023.117369openalex-snapshot

Application of biomarker-derived fluorescent probes for the detection of Alzheimer's disease

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c00933openalex-snapshot

Targeting Neuroinflammation and Cognitive Decline: First-in-Class Dual Butyrylcholinesterase and p38α Mitogen-Activated Protein Kinase Inhibitors

inferred← citeshttps://doi.org/10.1021/acsmedchemlett.5c00630openalex-snapshot

Functional Evaluation of Tetrahydroisoquinoline-Derived Ligands Reveals Distinct Modulatory Profiles at the Muscarinic M1 Receptor

inferred← citeshttps://doi.org/10.1021/acsomega.5c12400openalex-snapshot

N- Salicyloyl Tryptamine Derivatives Improve Mitochondrial Function To Treat Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1021/acsomega.6c01108openalex-snapshot

“Behavioral and Neuroinflammatory Evaluation of a Novel Isoxazole-5-One Derivative in Animal Models of Alzheimer’s Disease via TNF-α, COX-2, IL-6, and NF-κB Modulation”

inferred← citeshttps://doi.org/10.1038/s41392-024-01911-3openalex-snapshot

Recent advances in Alzheimer’s disease: mechanisms, clinical trials and new drug development strategies

inferred← citeshttps://doi.org/10.1038/s41467-024-50042-4openalex-snapshot

Histamine H1 receptors in dentate gyrus-projecting cholinergic neurons of the medial septum suppress contextual fear retrieval in mice

inferred← citeshttps://doi.org/10.1038/s41598-024-80102-0openalex-snapshot

The novel orthosteric agonist M1 muscarinic acetylcholine receptor reveals anti-Alzheimer’s disease activity

inferred← citeshttps://doi.org/10.1039/d3cp01480kopenalex-snapshot

Interactions with amyloid beta peptide and acetylcholinesterase increase alkaline phosphatase activity

inferred← citeshttps://doi.org/10.1039/d4md00060aopenalex-snapshot

Carltonine-derived compounds for targeted butyrylcholinesterase inhibition

inferred← citeshttps://doi.org/10.1039/d5tb02633dopenalex-snapshot

Advances in ultrasensitive detection technologies for blood-based biomarkers of Alzheimer's disease

inferred← citeshttps://doi.org/10.1039/d6ay01083kopenalex-snapshot

Engineering a nanocluster-immobilized MOF@MOF architecture-based ratiometric fluorescence bioassay for sensing neurodegenerative disease-related acetylcholinesterase and inhibitor drugs

inferred← citeshttps://doi.org/10.1080/07391102.2025.2458327openalex-snapshot

Pharmacophore-based virtual screening of the chromone derivatives as potential therapeutic for Alzheimer’s disease

inferred← citeshttps://doi.org/10.1080/14737175.2024.2313557openalex-snapshot

Are pharmacotherapeutics effective for treating aphasia?

inferred← citeshttps://doi.org/10.1080/14756366.2024.2313682openalex-snapshot

Novel anti-neuroinflammatory pyranone-carbamate derivatives as selective butyrylcholinesterase inhibitors for treating Alzheimer’s disease

inferred← citeshttps://doi.org/10.1093/braincomms/fcae204openalex-snapshot

Chronic inflammation with microglia senescence at basal forebrain: impact on cholinergic deficit in Alzheimer’s brain haemodynamics

inferred← citeshttps://doi.org/10.1093/ndt/gfaf029openalex-snapshot

Cholinergic system in patients with chronic kidney disease: cognitive and renal implications

inferred← citeshttps://doi.org/10.1097/md.0000000000040726openalex-snapshot

Exploring the potential mechanism of Polygonatum sibiricum for Alzheimer’s disease based on network pharmacology and molecular docking: An observational study

inferred← citeshttps://doi.org/10.1101/2024.06.19.598824openalex-snapshot

Interaction between mitochondrial translocator protein and aging in inflammatory responses in mouse hippocampus

inferred← citeshttps://doi.org/10.1109/jstqe.2025.3564366openalex-snapshot

Photobiomodulation Ameliorates Neuronal Damage in an Amyloid-Beta Induced Rat Model

inferred← citeshttps://doi.org/10.1111/acel.70039openalex-snapshot

Age‐Dependent Regulation of Hippocampal Inflammation by the Mitochondrial Translocator Protein in Mice

inferred← citeshttps://doi.org/10.1111/jnc.15683openalex-snapshot

Long‐term nucleus basalis cholinergic depletion induces attentional deficits and impacts cortical neurons and BDNF levels without affecting the NGF synthesis

inferred← citeshttps://doi.org/10.1111/jnc.16027openalex-snapshot

Recent advances in cholinergic mechanisms: A preface for the ISCM2022 special issue

inferred← citeshttps://doi.org/10.1111/jnc.16032openalex-snapshot

Brain energy metabolism: A roadmap for future research

inferred← citeshttps://doi.org/10.1111/jnc.70081openalex-snapshot

Evaluation of the Alterations in Central Cholinergic Neurotransmission in Aging and Amyloid Precursor Protein Knock‐In Mice

inferred← citeshttps://doi.org/10.1111/joim.70096openalex-snapshot

Co‐pathologies and biological processes beyond amyloid‐beta and tau in people with Alzheimer's disease: Evidence from clinical cohort studies

inferred← citeshttps://doi.org/10.1111/nan.12835openalex-snapshot

Early loss of locus coeruleus innervation promotes cognitive and neuropathological changes before amyloid plaque deposition in a transgenic rat model of Alzheimer's disease

inferred← citeshttps://doi.org/10.1126/sciadv.ado1508openalex-snapshot

Distinct septo-hippocampal cholinergic projections separately mediate stress-induced emotional and cognitive deficits

inferred← citeshttps://doi.org/10.1134/s0012500823700179openalex-snapshot

Ammonium Amphiphiles Based on Natural Compounds: Design, Synthesis, Properties, and Biomedical Applications. A Review

inferred← citeshttps://doi.org/10.1152/jn.00476.2024openalex-snapshot

Cortical acetylcholine response to deep brain stimulation of the basal forebrain in mice

inferred← citeshttps://doi.org/10.1155/2023/9935942openalex-snapshot

[Retracted] The Effective Components, Core Targets, and Key Pathways of Ginseng against Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1159/000537883openalex-snapshot

LINC00472 Regulates Ferroptosis of Neurons in Alzheimer’s Disease via FOXO1

inferred← citeshttps://doi.org/10.1177/13872877251325891openalex-snapshot

The unsafe profile of lecanemab

inferred← citeshttps://doi.org/10.1177/13872877251400667openalex-snapshot

Dysregulated mTOR signaling in Alzheimer's disease: Linking pathogenic mechanisms to emerging therapeutic strategies

inferred← citeshttps://doi.org/10.1177/13872877261417548openalex-snapshot

Serious doubts about amyloid-β (Aβ) biomarkers and anti-Aβ immunotherapy

inferred← citeshttps://doi.org/10.1186/s13195-024-01536-2openalex-snapshot

Effects of strategic white matter hyperintensities of cholinergic pathways on basal forebrain volume in patients with amyloid-negative neurocognitive disorders

inferred← citeshttps://doi.org/10.1186/s13195-026-02051-2openalex-snapshot

Aging alters the vulnerability pattern to amyloid-beta oligomers in wild-type mice: a behavioral and neurobiological study

inferred← citeshttps://doi.org/10.1248/bpb.b22-00797openalex-snapshot

Plantainoside B in Bacopa monniera Binds to Aβ Aggregates Attenuating Neuronal Damage and Memory Deficits Induced by Aβ

inferred← citeshttps://doi.org/10.1248/bpb.b25-00308openalex-snapshot

Stimulation of α7 Nicotinic Acetylcholine Receptors by PNU282987 Demonstrates Efferocytosis-Like Activation and Neuroprotection in Human Models of Microglia and Cholinergic Neurons under the Pathophysiological Conditions of Alzheimer’s Disease

inferred← citeshttps://doi.org/10.1523/jneurosci.2148-24.2025openalex-snapshot

MiR-153 Prevents NRF2 Nuclear Translocation to Drive Hypoperfusion-Related Cognitive Deficits by Targeting KPNA5

inferred← citeshttps://doi.org/10.1590/1980-5764-dn-2025-0290openalex-snapshot

Non-pharmacological strategies for the management of Alzheimer's disease

inferred← citeshttps://doi.org/10.21203/rs.3.rs-4225413/v1openalex-snapshot

Exploring the potential mechanism of Polygonatum sibiricum for Alzheimer's disease based on network pharmacology and molecular docking

inferred← citeshttps://doi.org/10.21203/rs.3.rs-7399280/v1openalex-snapshot

Network Pharmacology-guided Identification and Molecular Validation of Multi-Target Phytoconstituents from Gmelina arborea against Alzheimer’s Disease

inferred← citeshttps://doi.org/10.21203/rs.3.rs-7399280/v2openalex-snapshot

Network Pharmacology-guided Identification and Molecular Validation of Multi-Target Phytoconstituents from Gmelina arborea against Alzheimer’s Disease

inferred← citeshttps://doi.org/10.21203/rs.3.rs-7521725/v1openalex-snapshot

Exploring potential inhibitors from Eriobotrya japonica targeting AChE and BChE in Alzheimer's Disease through docking, ADMET profiling, and DFT analysis

inferred← citeshttps://doi.org/10.2174/0115734080401748250711113148openalex-snapshot

In Vitro Investigation of Acetylcholinesterase Inhibition by Methanolic Extract of Muntingia calabura Bark

inferred← citeshttps://doi.org/10.2174/0118715249302264240715060630openalex-snapshot

Targeting Adenylate Cyclase: A Novel Concept for Stimulation of Neurogenesis and Pharmacotherapy of Alzheimer's Disease

inferred← citeshttps://doi.org/10.2174/1567205020666230309113749openalex-snapshot

Effect of APOE4 Allele and Gender on the Rate of Atrophy in the Hippocampus, Entorhinal Cortex, and Fusiform Gyrus in Alzheimer’s Disease

inferred← citeshttps://doi.org/10.2174/1573408019666230816143357openalex-snapshot

Insight into JNK Inhibition-based Strategy for the Treatment of Alzheimer's Disease

inferred← citeshttps://doi.org/10.2174/9798898812553125010009openalex-snapshot

The Role of Nutraceuticals in the Treatment of Neurodegenerative Diseases

inferred← citeshttps://doi.org/10.2174/9798898815646126010005openalex-snapshot

Tau Protein in Alzheimer's Disease

inferred← citeshttps://doi.org/10.22533/at.ed.15934123010610openalex-snapshot

PHARMACOLOGICAL TREATMENT OF ALZHEIMER'S DISEASE: AN INTEGRATIVE REVIEW ON THE EFFECTIVENESS OF CHOLINESTERASE AND MEMANTINE INHIBITORS

inferred← citeshttps://doi.org/10.31083/jin23090openalex-snapshot

Current Status of Plant-Based Bioactive Compounds as Therapeutics in Alzheimer’s Diseases

inferred← citeshttps://doi.org/10.31083/jin26903openalex-snapshot

5-Fluorouracil Impairs Transmission of Acetylcholine in the Hippocampus and Induces Cognitive Impairments in Mice

inferred← citeshttps://doi.org/10.31857/s0044467724050026openalex-snapshot

The role of the basal forebrain in the pathogenesis of Alzheimer’s disease

inferred← citeshttps://doi.org/10.31857/s2686953522600544openalex-snapshot

AMMONIUM AMPHIPHILES BASED ON NATURAL COMPOUNDS: DESIGN, SYNTHESIS, PROPERTIES AND BIOMEDICAL APPLICATIONS. A REVIEW

inferred← citeshttps://doi.org/10.3233/adr-240035openalex-snapshot

Caring for Individuals with Alzheimer’s Disease: A Spotlight on Hispanic Caregivers

inferred← citeshttps://doi.org/10.3389/fchem.2025.1479763openalex-snapshot

dyphAI dynamic pharmacophore modeling with AI: a tool for efficient screening of new acetylcholinesterase inhibitors

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1722477openalex-snapshot

Nerve growth factor responsive elements modulate immune cell inflammation and are dysregulated in an Alzheimer’s disease mouse model

inferred← citeshttps://doi.org/10.3389/fnagi.2022.876019openalex-snapshot

Phenotypic Displays of Cholinergic Enzymes Associate With Markers of Inflammation, Neurofibrillary Tangles, and Neurodegeneration in Pre- and Early Symptomatic Dementia Subjects

inferred← citeshttps://doi.org/10.3389/fnagi.2025.1518198openalex-snapshot

Associations between peripheral nerve stimulation and cognitive performance: insights from healthy individuals and various disease pathologies

inferred← citeshttps://doi.org/10.3389/fneur.2025.1505739openalex-snapshot

Evaluation of vascular cognitive impairment and identification of imaging markers using machine learning: a multimodal MRI study

inferred← citeshttps://doi.org/10.3389/fnins.2022.998224openalex-snapshot

Predictors of response to acetylcholinesterase inhibitors in dementia: A systematic review

inferred← citeshttps://doi.org/10.3389/fnmol.2022.941467openalex-snapshot

Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer’s and Parkinson’s disease

inferred← citeshttps://doi.org/10.3389/fphar.2022.941656openalex-snapshot

Landscape of immune infiltration in entorhinal cortex of patients with Alzheimerʼs disease

inferred← citeshttps://doi.org/10.3389/fphar.2023.1276100openalex-snapshot

Impairment of exocytotic transmitter release by decynium-22 through an inhibition of ion channels

inferred← citeshttps://doi.org/10.3389/fphar.2025.1694610openalex-snapshot

From heart to brain: cognitive potential of propranolol and diltiazem through cholinergic enhancement via butyrylcholinesterase inhibition

inferred← citeshttps://doi.org/10.3389/fphar.2026.1929468openalex-snapshot

Adult-onset hippocampal α7 nicotinic acetylcholine receptor loss rapidly drives Alzheimer-like neuropathology in mice

inferred← citeshttps://doi.org/10.3390/biology14091114openalex-snapshot

Mulberroside A: A Multi-Target Neuroprotective Agent in Alzheimer’s Disease via Cholinergic Restoration and PI3K/AKT Pathway Activation

inferred← citeshttps://doi.org/10.3390/biom15010110openalex-snapshot

Anxiolytic, Antidepressant, and Anticholinesterase Effects of Essential Oil from Myrcia sylvatica (G.Mey.) DC

inferred← citeshttps://doi.org/10.3390/biom15081188openalex-snapshot

Apelin-13-Mediated Upregulation of METTL3 Ameliorates Alzheimer’s Disease via Inhibiting Neuroinflammation Through m6A-Dependent Regulation of lncRNA BDNF-AS

inferred← citeshttps://doi.org/10.3390/biom16050726openalex-snapshot

Akkermansia muciniphila and Alzheimer’s Disease: Mechanisms, Evidence and Translational Potential

inferred← citeshttps://doi.org/10.3390/brainsci14060590openalex-snapshot

Research Progress on the Pathogenesis, Diagnosis, and Drug Therapy of Alzheimer’s Disease

inferred← citeshttps://doi.org/10.3390/cimb46070407openalex-snapshot

Muscarinic Receptors and Alzheimer’s Disease: New Perspectives and Mechanisms

inferred← citeshttps://doi.org/10.3390/ijms24010507openalex-snapshot

Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids

inferred← citeshttps://doi.org/10.3390/ijms24021340openalex-snapshot

Mechanistic Insights, Treatment Paradigms, and Clinical Progress in Neurological Disorders: Current and Future Prospects

inferred← citeshttps://doi.org/10.3390/ijms24076598openalex-snapshot

Δ8-THC Protects against Amyloid Beta Toxicity Modulating ER Stress In Vitro: A Transcriptomic Analysis

inferred← citeshttps://doi.org/10.3390/ijms241512025openalex-snapshot

The Sigma Receptors in Alzheimer’s Disease: New Potential Targets for Diagnosis and Therapy

inferred← citeshttps://doi.org/10.3390/ijms25073892openalex-snapshot

Alzheimer’s Amyloid Hypothesis and Antibody Therapy: Melting Glaciers?

inferred← citeshttps://doi.org/10.3390/ijms26031234openalex-snapshot

Deciphering the Functions of Raphe–Hippocampal Serotonergic and Glutamatergic Circuits and Their Deficits in Alzheimer’s Disease

inferred← citeshttps://doi.org/10.3390/ijms26146980openalex-snapshot

Alzheimer’s Disease Etiology Hypotheses and Therapeutic Strategies: A Perspective

inferred← citeshttps://doi.org/10.3390/ijms26199444openalex-snapshot

Alzheimer’s Disease: From Molecular Mechanisms to Promising Therapeutic Strategies

inferred← citeshttps://doi.org/10.3390/ijms26199670openalex-snapshot

The Central Cholinergic Synapse: A Primer

inferred← citeshttps://doi.org/10.3390/ijms27104556openalex-snapshot

Network Pharmacology Reveals the Therapeutic Potential of BBB-Permeable Compounds from Lonicera caerulea for Alzheimer’s Disease and Lipid Metabolism Disorders

inferred← citeshttps://doi.org/10.3390/life13010221openalex-snapshot

Involvement of an Aberrant Vascular System in Neurodevelopmental, Neuropsychiatric, and Neuro-Degenerative Diseases

inferred← citeshttps://doi.org/10.3390/md23030091openalex-snapshot

The Advancements of Marine Natural Products in the Treatment of Alzheimer’s Disease: A Study Based on Cell and Animal Experiments

inferred← citeshttps://doi.org/10.3390/medsci14040426openalex-snapshot

Concurrent Use of Anticholinergic and Antidementia Medicines in Older Adults with Dementia: A Systematic Review of Prevalence, Predictors and Clinical Outcomes

inferred← citeshttps://doi.org/10.3390/molecules29215131openalex-snapshot

Recent Advances in Therapeutics for the Treatment of Alzheimer’s Disease

inferred← citeshttps://doi.org/10.3390/nu16081232openalex-snapshot

L-Carnitine in the Treatment of Psychiatric and Neurological Manifestations: A Systematic Review

inferred← citeshttps://doi.org/10.3390/ph15101214openalex-snapshot

Synthesis, Biological Evaluation and Machine Learning Prediction Model for Fluorinated Cinchona Alkaloid-Based Derivatives as Cholinesterase Inhibitors

inferred← citeshttps://doi.org/10.3390/ph18121871openalex-snapshot

Pharmacokinetic and Pharmacodynamic Evaluation of PZ-2891, an Anti-Alzheimer’s Disease Agonist of PANK2

inferred← citeshttps://doi.org/10.62993/cmed.2024.2.1openalex-snapshot

Dementia. Specifics of its manifestations. Clinical patterns of dementia in Alzheimer's disease

inferred← citeshttps://doi.org/10.7759/cureus.31065openalex-snapshot

Conventional Versus New Treatment: Comparing the Effects of Acetylcholinesterase Inhibitors and N-Methyl-D-Aspartate Receptor Antagonist With Aducanumab

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