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Shigella Isolates From the Global Enteric Multicenter Study Inform Vaccine Development

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1006/mpat.2000.0404openalex-snapshot
Genetic organization of the she pathogenicity island in Shigella flexneri 2a
inferredcites →https://doi.org/10.1016/0264-410x(90)90094-3openalex-snapshot
Studies in volunteers to evaluate candidate Shigella vaccines: further experience with a bivalent Salmonella typhi-Shigella sonnei vaccine and protection conferred by previous Shigella sonnei disease
inferredcites →https://doi.org/10.1016/0264-410x(95)00102-7openalex-snapshot
A modified Shigella volunteer challenge model in which the inoculum is administered with bicarbonate buffer: clinical experience and implications for Shigella infectivity
inferredcites →https://doi.org/10.1016/0264-410x(96)00006-0openalex-snapshot
Cross-reactivity of Shigella flexneri serotype 2a O antigen antibodies following immunization or infection
inferredcites →https://doi.org/10.1016/j.carres.2011.02.013openalex-snapshot
Structural elucidation of the O-antigen of the Shigella flexneri provisional serotype 88-893: structural and serological similarities with S. flexneri provisional serotype Y394 (1c)
inferredcites →https://doi.org/10.1016/j.vaccine.2006.03.039openalex-snapshot
Enteric infections and the vaccines to counter them: Future directions
inferredcites →https://doi.org/10.1016/j.vaccine.2009.12.050openalex-snapshot
Age-related efficacy of Shigella O-specific polysaccharide conjugates in 1–4-year-old Israeli children
inferredcites →https://doi.org/10.1016/s0140-6736(13)60844-2openalex-snapshot
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
inferredcites →https://doi.org/10.1016/s0140-6736(96)06255-1openalex-snapshot
Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults
inferredcites →https://doi.org/10.1038/nrgastro.2013.12openalex-snapshot
Progress and pitfalls in Shigella vaccine research
inferredcites →https://doi.org/10.1038/nrmicro1662openalex-snapshot
Clinical trials of Shigella vaccines: two steps forward and one step back on a long, hard road
inferredcites →https://doi.org/10.1056/nejm199111143252006openalex-snapshot
Diarrheal Disease during Operation Desert Shield
inferredcites →https://doi.org/10.1086/424680openalex-snapshot
Deletion in theShigellaEnterotoxin Genes Further AttenuatesShigella flexneri2a Bearing Guanine Auxotrophy in a Phase 1 Trial of CVD 1204 and CVD 1208
inferredcites →https://doi.org/10.1086/427501openalex-snapshot
Gastroenteritis in US Marines during Operation Iraqi Freedom
inferredcites →https://doi.org/10.1093/cid/cis753openalex-snapshot
The Global Enteric Multicenter Study (GEMS) of Diarrheal Disease in Infants and Young Children in Developing Countries: Epidemiologic and Clinical Methods of the Case/Control Study
inferredcites →https://doi.org/10.1093/cid/cis754openalex-snapshot
Diagnostic Microbiologic Methods in the GEMS-1 Case/Control Study
inferredcites →https://doi.org/10.1093/cid/cis761openalex-snapshot
The Global Enteric Multicenter Study (GEMS): Impetus, Rationale, and Genesis
inferredcites →https://doi.org/10.1093/cid/cis787openalex-snapshot
Some Epidemiologic, Clinical, Microbiologic, and Organizational Assumptions That Influenced the Design and Performance of the Global Enteric Multicenter Study (GEMS)
inferredcites →https://doi.org/10.1093/infdis/122.3.181openalex-snapshot
Epidemic Shiga Bacillus Dysentery in Central America. II. Epidemiologic Studies in 1969
inferredcites →https://doi.org/10.1093/infdis/125.1.12openalex-snapshot
Immunity in Shigellosis. II. Protection Induced by Oral Live Vaccine or Primary Infection
inferredcites →https://doi.org/10.1093/infdis/132.1.15openalex-snapshot
An Outbreak of Dysentery Caused by Shigella dysenteriae Type 1 on a Coral Island in the Bay of Bengal
inferredcites →https://doi.org/10.1093/infdis/157.5.1068openalex-snapshot
Serum Antibodies to Lipopolysaccharide and Natural Immunity to Shigellosis in an Israeli Military Population
inferredcites →https://doi.org/10.1093/infdis/164.3.533openalex-snapshot
Effect of Prior Infection with Virulent Shigella flexneri 2a on the Resistance of Monkeys to Subsequent Infection with Shigella sonnei
inferredcites →https://doi.org/10.1093/infdis/172.5.1408openalex-snapshot
Prevalence of Shigella Enterotoxin 1 among Shigella Clinical Isolates of Diverse Serotypes
inferredcites →https://doi.org/10.1093/oxfordjournals.aje.a116134openalex-snapshot
Epidemiologic Patterns of Acute Diarrhea and Endemic Shigella Infections in Children in a Poor Periurban Setting in Santiago, Chile
inferredcites →https://doi.org/10.1111/j.1365-3156.2006.01723.xopenalex-snapshot
Distribution of Shigella enterotoxin genes and secreted autotransporter toxin gene among diverse species and serotypes of shigella isolated from Andaman Islands, India
inferredcites →https://doi.org/10.1128/aem.19.3.434-437.1970openalex-snapshot
Comparison of Media for Direct Isolation and Transport of Shigellae from Fecal Specimens
inferredcites →https://doi.org/10.1128/iai.06174-11openalex-snapshot
Broadly Protective Shigella Vaccine Based on Type III Secretion Apparatus Proteins
inferredcites →https://doi.org/10.1128/iai.67.2.782-788.1999openalex-snapshot
Strategy for Cross-Protection among Shigella flexneri Serotypes
inferredcites →https://doi.org/10.1128/iai.67.7.3437-3443.1999openalex-snapshot
Vaccination against Shigellosis with Attenuated Shigella flexneri 2a Strain SC602
inferredcites →https://doi.org/10.1128/jb.187.2.619-628.2005openalex-snapshot
Evolutionary Genetics of a New Pathogenic Escherichia Species: Escherichia albertii and Related Shigella boydii Strains
inferredcites →https://doi.org/10.1128/jcm.02713-12openalex-snapshot
Quantitative PCR for Detection of Shigella Improves Ascertainment of Shigella Burden in Children with Moderate-to-Severe Diarrhea in Low-Income Countries
inferredcites →https://doi.org/10.1128/jcm.29.2.386-389.1991openalex-snapshot
Prospective study of the association between serum antibodies to lipopolysaccharide O antigen and the attack rate of shigellosis
inferredcites →https://doi.org/10.1136/gut.40.4.505openalex-snapshot
Effect of shigella enterotoxin 1 (ShET1) on rabbit intestine in vitro and in vivo.
inferredcites →https://doi.org/10.1172/jci117991openalex-snapshot
Shigella enterotoxin 1: an enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro.
inferredcites →https://doi.org/10.1371/journal.pmed.0030353openalex-snapshot
A Multicentre Study of Shigella Diarrhoea in Six Asian Countries: Disease Burden, Clinical Manifestations, and Microbiology
inferredcites →https://doi.org/10.1371/journal.pntd.0002280openalex-snapshot
Housefly Population Density Correlates with Shigellosis among Children in Mirzapur, Bangladesh: A Time Series Analysis
inferredcites →https://doi.org/10.2307/587237openalex-snapshot
Bulletin of the World Health Organization
inferredcites →https://doi.org/10.2471/blt.12.112433openalex-snapshot
Stockpiling oral cholera vaccine
inferredcites →https://doi.org/10.4049/jimmunol.164.4.2221openalex-snapshot
Production of IFN-γ and IL-10 to Shigella Invasins by Mononuclear Cells from Volunteers Orally Inoculated with a Shiga Toxin-Deleted Shigella dysenteriae Type 1 Strain
inferredcites →https://doi.org/10.4161/hv.4746openalex-snapshot
Safety and Immunogenicity of CVD 1208S, a Live, OralΔguaBA Δsen Δset Shigella flexneri2a Vaccine Grown on Animal-Free Media
inferredcites →https://doi.org/10.4269/ajtmh.1971.20.934openalex-snapshot
Epidemic Shiga-Bacillus Dysentery in Central America
inferredcites →https://doi.org/10.4269/ajtmh.1984.33.1192openalex-snapshot
Epidemic Shiga Bacillus Dysentery in Central Africa

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Epidemiology of Shigella Species and Serotypes in Children: Results from the Mal-Ed Study
inferred← citeshttps://doi.org/10.2139/ssrn.5386776openalex-extracted
Incidence and Antimicrobial Resistance of Shigella-Attributable Diarrhea in Young Children: Results from the Multi-Country Enterics for Global Health (EFGH) Shigella Surveillance Study
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Efficient Iterative Synthesis of O‐Acetylated Tri‐ to Pentadecasaccharides Related to the Lipopolysaccharide of Shigella flexneri Type 3 a through Di‐ and Trisaccharide Glycosyl Donors
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Detailed Investigation of the Immunodominant Role of O‐Antigen Stoichiometric O‐Acetylation as Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD‐NMR Spectroscopy for Shigella flexneri 3a
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Shigella-Controlled Human Infection Models: Current and Future Perspectives
inferred← citeshttps://doi.org/10.1007/978-3-030-80068-0_15openalex-snapshot
Bacterial Infections of the Small and Large Intestine
inferred← citeshttps://doi.org/10.1007/978-3-031-64288-3_10openalex-snapshot
Shigellosis: The Road from Multiple Drug-Resistance (MDR) to Vaccine Development
inferred← citeshttps://doi.org/10.1007/978-3-031-86002-7_20openalex-snapshot
The Impact of Antibiotic Resistance Genes in Shigellosis
inferred← citeshttps://doi.org/10.1007/s00203-020-02034-3openalex-snapshot
Shigella sonnei: virulence and antibiotic resistance
inferred← citeshttps://doi.org/10.1007/s00253-021-11295-xopenalex-snapshot
Antimicrobial and anti-biofilm activity of thymoquinone against Shigella flexneri
inferred← citeshttps://doi.org/10.1007/s00253-021-11701-4openalex-snapshot
Efficient production of immunologically active Shigella invasion plasmid antigens IpaB and IpaH using a cell-free expression system
inferred← citeshttps://doi.org/10.1007/s10989-018-9698-5openalex-snapshot
Designing a Novel Multi-epitope Peptide Vaccine Against Pathogenic Shigella spp. Based Immunoinformatics Approaches
inferred← citeshttps://doi.org/10.1007/s12029-019-00301-1openalex-snapshot
Effects of Curcumin and Silymarin on the Shigella dysenteriae and Campylobacter jejuni In vitro
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Deciphering Distinct Pathogenetic Strategies Employed by Shigella Serotypes Using Human Intestinal Organoids
inferred← citeshttps://doi.org/10.1007/s12551-021-00791-zopenalex-snapshot
Glycoconjugate vaccines against Salmonella enterica serovars and Shigella species: existing and emerging methods for their analysis
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Structural chemistry and molecular-level interactome reveals histidine kinase EvgS to subvert both antimicrobial resistance and virulence in Shigella flexneri 2a str. 301
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The Epidemiology of Diarrhea in Children Under 5 Years of Age in Mozambique
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Shigella spp.
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Shigella
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Oral Shigella Vaccines
inferred← citeshttps://doi.org/10.1016/b978-0-12-820954-7.00007-4openalex-snapshot
NMR characterization of bacterial glycans and glycoconjugate vaccines
inferred← citeshttps://doi.org/10.1016/b978-0-12-822521-9.00091-5openalex-snapshot
Shigella
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Nanoparticles in biosensor development for the detection of pathogenic bacteria in water
inferred← citeshttps://doi.org/10.1016/b978-0-323-40181-4.00147-xopenalex-snapshot
Shigella Species
inferred← citeshttps://doi.org/10.1016/b978-0-323-55512-8.00022-3openalex-snapshot
Approach to the Patient With Diarrhea
inferred← citeshttps://doi.org/10.1016/b978-0-323-75608-2.00057-4openalex-snapshot
Inflammatory Enterocolitis
inferred← citeshttps://doi.org/10.1016/b978-0-323-75608-2.00147-6openalex-snapshot
Shigella Species
inferred← citeshttps://doi.org/10.1016/b978-0-323-82763-8.00109-6openalex-snapshot
Shigella
inferred← citeshttps://doi.org/10.1016/b978-0-323-85730-7.00023-0openalex-snapshot
Mechanisms of gastrointestinal pathogenesis and landscape of intestinal immunity
inferred← citeshttps://doi.org/10.1016/b978-0-323-99886-4.00020-xopenalex-snapshot
The phylogenomics of Shigella spp.
inferred← citeshttps://doi.org/10.1016/b978-84-9113-949-2.00110-4openalex-snapshot
10.1016/b978-84-9113-949-2.00110-4
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Shift in serotype distribution of Shigella species in China, 2003–2013
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Update on vaccines for enteric pathogens
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Threshold protective levels of serum IgG to Shigella lipopolysaccharide: re-analysis of Shigella vaccine trials data
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Safety Profile and Immunologic Responses of a Novel Vaccine Against Shigella sonnei Administered Intramuscularly, Intradermally and Intranasally: Results From Two Parallel Randomized Phase 1 Clinical Studies in Healthy Adult Volunteers in Europe
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Efficacy, safety, and immunogenicity of the Shigella sonnei 1790GAHB GMMA candidate vaccine: Results from a phase 2b randomized, placebo-controlled challenge study in adults
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Shigelosis, la importancia de la higiene en la prevención
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Enteropatógenos y antibióticos
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Enteropathogens and antibiotics
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Antibacterial activity of gallic acid against Shigella flexneri and its effect on biofilm formation by repressing mdoH gene expression
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Mechanisms of resistance and decreased susceptibility to azithromycin in Shigella
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Antibiotic resistance and molecular characterization of shigella isolates recovered from children aged less than 5 years in Manhiça, Southern Mozambique
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Burden and risk factors of Shigella sonnei shigellosis among children aged 0–59 months in hyperendemic communities in Israel
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Virulence factors and mechanisms of antimicrobial resistance in Shigella strains from periurban areas of Lima (Peru)
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Quantitative proteomic analysis of Shigella flexneri and Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) reveals highly pure preparations
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A global overview of the most important zoonotic bacteria pathogens transmitted from Rattus norvegicus to humans in urban environments
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Global distribution and genomic characteristics of Shigella: A genomic epidemiological study
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Antibacterial and antishigellosis activity of Xylopia staudtii (engl. & diels), Annonaceae
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First report on whole-genome shotgun sequences of 23 biochemically indistinguishable clinical Shigella isolates
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Epidemiology of Shigella species and serotypes in children: a retrospective substudy of the MAL-ED observational birth cohort study
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Photodynamic inactivation of Shigella flexneri by curcumin
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Virulence profiling of Shigella flexneri and emergence of serotype 2b as a highly virulent shigellosis causing strain in Pakistan
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A tetravalent Shigella outer membrane vesicles based candidate vaccine offered cross-protection against all the serogroups of Shigella in adult mice
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In silico design of a vaccine candidate based on autotransporters and HSP against the causal agent of shigellosis, Shigella flexneri
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The tale of the traveling cheese: Shigella in a lung transplant patient
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Spatiotemporal variations in the incidence of bacillary dysentery and long-term effects associated with meteorological and socioeconomic factors in China from 2013 to 2017
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Impact of water, sanitation, and hygiene indicators on enteric viral pathogens among under-5 children in low resource settings
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Multi drug resistance and Extended Spectrum Beta Lactamases in clinical isolates of Shigella: A study from New Delhi, India
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Shigellosis in Southeast Asia: A systematic review and meta-analysis
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Safety and immunogenicity of a candidate bioconjugate vaccine against Shigella dysenteriae type 1 administered to healthy adults: A single blind, partially randomized Phase I study
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Status of vaccine research and development for Shigella
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Development of recombinant vaccine candidate molecule against Shigella infection
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Global burden of diarrheal diseases among children in developing countries: Incidence, etiology, and insights from new molecular diagnostic techniques
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Vaccination with Shigella flexneri 2a conjugate induces type 2a and cross-reactive type 6 antibodies in humans but not in mice
inferred← citeshttps://doi.org/10.1016/j.vaccine.2017.09.083openalex-snapshot
Considerations for using ETEC and Shigella disease burden estimates to guide vaccine development strategy
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WHO consultation on ETEC and Shigella burden of disease, Geneva, 6–7th April 2017: Meeting report
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Evaluation of a conjugate vaccine platform against enterotoxigenic Escherichia coli (ETEC), Campylobacter jejuni and Shigella
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Highly homogenous tri-acylated S-LPS acts as a novel clinically applicable vaccine against Shigella flexneri 2a infection
inferred← citeshttps://doi.org/10.1016/j.vaccine.2019.03.036openalex-snapshot
How can controlled human infection models accelerate clinical development and policy pathways for vaccines against Shigella?
inferred← citeshttps://doi.org/10.1016/j.vaccine.2022.12.037openalex-snapshot
Vaccine value profile for Shigella
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Development of Shigella conjugate vaccines targeting Shigella flexneri 2a and S. flexneri 3a using a simple platform-approach conjugation by squaric acid chemistry
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GMP manufacture of Shigella flexneri 2a Artificial Invaplex (InvaplexAR) and evaluation in a Phase 1 Open-label, dose escalating study administered intranasally to healthy, adult volunteers
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Development of a Shigella conjugate vaccine targeting Shigella flexneri 6 that is immunogenic and provides protection against virulent challenge
inferred← citeshttps://doi.org/10.1016/j.vaccine.2025.126779openalex-snapshot
BECC-engineered live-attenuated Shigella vaccine candidates display reduced endotoxicity with robust immunogenicity in mice
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Qualification of a high-throughput luminescence-based Serum Bactericidal Activity assay to assess the functionality of human sera against five Shigella serotypes
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The extant World War 1 dysentery bacillus NCTC1: a genomic analysis
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Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study
inferred← citeshttps://doi.org/10.1016/s0140-6736(17)33296-8openalex-snapshot
Shigellosis
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Shigellosis
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Intercontinental dissemination of azithromycin-resistant shigellosis through sexual transmission: a cross-sectional study
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Morbidity and mortality due to shigella and enterotoxigenic Escherichia coli diarrhoea: the Global Burden of Disease Study 1990–2016
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Safety and immunogenicity of a synthetic carbohydrate conjugate vaccine against Shigella flexneri 2a in healthy adult volunteers: a phase 1, dose-escalating, single-blind, randomised, placebo-controlled study
inferred← citeshttps://doi.org/10.1016/s2214-109x(17)30392-3openalex-snapshot
Identification and management of Shigella infection in children with diarrhoea: a systematic review and meta-analysis
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Spatiotemporal variation in risk of Shigella infection in childhood: a global risk mapping and prediction model using individual participant data
inferred← citeshttps://doi.org/10.1016/s2214-109x(23)00421-7openalex-snapshot
Clinical and regulatory development strategies for Shigella vaccines intended for children younger than 5 years in low-income and middle-income countries
inferred← citeshttps://doi.org/10.1016/s2214-109x(25)00534-0openalex-snapshot
The incidence and antimicrobial resistance of Shigella-attributable diarrhoea in young children in low-income and middle-income countries from the multicountry Enterics for Global Health (EFGH) Shigella Surveillance Study: a prospective, facility-based hybrid surveillance study
inferred← citeshttps://doi.org/10.1017/s0950268818000912openalex-snapshot
Shigella infection in children under 5 years old in western French Guiana
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.5b00617openalex-snapshot
A Synthetic Carbohydrate Conjugate Vaccine Candidate against Shigellosis: Improved Bioconjugation and Impact of Alum on Immunogenicity
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Discovery of Semi- and Fully-Synthetic Carbohydrate Vaccines Against Bacterial Infections Using a Medicinal Chemistry Approach
inferred← citeshttps://doi.org/10.1021/acs.joc.0c00777openalex-snapshot
Convergent Chemoenzymatic Strategy to Deliver a Diversity of Shigella flexneri Serotype-Specific O-Antigen Segments from a Unique Lightly Protected Tetrasaccharide Core
inferred← citeshttps://doi.org/10.1021/acs.joc.5b01407openalex-snapshot
Investigation on the Synthesis of Shigella flexneri Specific Oligosaccharides Using Disaccharides as Potential Transglucosylase Acceptor Substrates
inferred← citeshttps://doi.org/10.1021/acs.jpcb.0c01595openalex-snapshot
Effects of Glucosylation and O-Acetylation on the Conformation of Shigella flexneri Serogroup 2 O-Antigen Vaccine Targets
inferred← citeshttps://doi.org/10.1021/acscentsci.1c01479openalex-snapshot
The First-in-Human Synthetic Glycan-Based Conjugate Vaccine Candidate against Shigella
inferred← citeshttps://doi.org/10.1021/acsinfecdis.0c00889openalex-snapshot
Target Product Profile and Development Path for Shigellosis Treatment with Antibacterials
inferred← citeshttps://doi.org/10.1021/bk-2018-1290.ch002openalex-snapshot
Glycoconjugate Vaccines: The Clinical Journey
inferred← citeshttps://doi.org/10.1021/bk-2018-1290.ch007openalex-snapshot
The Role of Molecular Modeling in Predicting Carbohydrate Antigen Conformation and Understanding Vaccine Immunogenicity
inferred← citeshttps://doi.org/10.1038/icb.2015.24openalex-snapshot
Shigella IpaB and IpaD displayed on L. lactis bacterium‐like particles induce protective immunity in adult and infant mice
inferred← citeshttps://doi.org/10.1038/nmicrobiol.2016.204openalex-snapshot
Deletion of toxin–antitoxin systems in the evolution of Shigella sonnei as a host-adapted pathogen
inferred← citeshttps://doi.org/10.1038/nrmicro.2016.10openalex-snapshot
The genomic signatures of Shigella evolution, adaptation and geographical spread
inferred← citeshttps://doi.org/10.1038/s41467-021-22700-4openalex-snapshot
Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei
inferred← citeshttps://doi.org/10.1038/s41467-023-43345-5openalex-snapshot
The genomic epidemiology of shigellosis in South Africa
inferred← citeshttps://doi.org/10.1038/s41467-025-64057-yopenalex-snapshot
Enhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei
inferred← citeshttps://doi.org/10.1038/s41541-022-00497-7openalex-snapshot
Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens
inferred← citeshttps://doi.org/10.1038/s41541-023-00624-yopenalex-snapshot
A Shigella flexneri 2a synthetic glycan-based vaccine induces a long-lasting immune response in adults
inferred← citeshttps://doi.org/10.1038/s41541-023-00725-8openalex-snapshot
A next-generation GMMA-based vaccine candidate to fight shigellosis
inferred← citeshttps://doi.org/10.1038/s41541-025-01305-8openalex-snapshot
Evaluation of cross-functional antibody responses elicited by a four-component GMMA Shigella vaccine
inferred← citeshttps://doi.org/10.1038/s41564-021-01054-zopenalex-snapshot
Pathogenomic analyses of Shigella isolates inform factors limiting shigellosis prevention and control across LMICs
inferred← citeshttps://doi.org/10.1038/s41579-024-01126-xopenalex-snapshot
Shigella sonnei: epidemiology, evolution, pathogenesis, resistance and host interactions
inferred← citeshttps://doi.org/10.1038/s41598-018-25764-3openalex-snapshot
Genomic epidemiology of Shigella in the United Kingdom shows transmission of pathogen sublineages and determinants of antimicrobial resistance
inferred← citeshttps://doi.org/10.1038/s41598-019-39810-1openalex-snapshot
Mutational convergence acts as a major player in adaptive parallel evolution of Shigella spp.
inferred← citeshttps://doi.org/10.1038/s41598-020-71754-9openalex-snapshot
Pre-existing Helicobacter pylori serum IgG enhances the vibriocidal antibody response to CVD 103-HgR live oral cholera vaccine in Malian adults
inferred← citeshttps://doi.org/10.1038/s41598-021-81719-1openalex-snapshot
Redirecting substrate regioselectivity using engineered ΔN123-GBD-CD2 branching sucrases for the production of pentasaccharide repeating units of S. flexneri 3a, 4a and 4b haptens
inferred← citeshttps://doi.org/10.1038/s41598-021-92132-zopenalex-snapshot
Associated factors, post infection child growth, and household cost of invasive enteritis among under 5 children in Bangladesh
inferred← citeshttps://doi.org/10.1038/s41598-021-98910-zopenalex-snapshot
Morphological, biological, and genomic characterization of a newly isolated lytic phage Sfk20 infecting Shigella flexneri, Shigella sonnei, and Shigella dysenteriae1
inferred← citeshttps://doi.org/10.1038/s41598-021-99384-9openalex-snapshot
Computer-aided engineering of a branching sucrase for the glucodiversification of a tetrasaccharide precursor of S. flexneri antigenic oligosaccharides
inferred← citeshttps://doi.org/10.1038/s41598-024-59181-6openalex-snapshot
Field evaluation of a simple and rapid diagnostic test, RLDT to detect Shigella and enterotoxigenic E. coli in Indian children
inferred← citeshttps://doi.org/10.1039/c4cc08805kopenalex-snapshot
Programmed chemo-enzymatic synthesis of the oligosaccharide component of a carbohydrate-based antibacterial vaccine candidate
inferred← citeshttps://doi.org/10.1039/c6em00222fopenalex-snapshot
Environmental transmission of diarrheal pathogens in low and middle income countries
inferred← citeshttps://doi.org/10.1051/e3sconf/202560301015openalex-snapshot
Potential of a novel and thermostable recombinant phage endolysin of Escherichia phage KW1E_UTAR against Shigella spp.
inferred← citeshttps://doi.org/10.1074/jbc.m114.566570openalex-snapshot
Modulation of Endotoxicity of Shigella Generalized Modules for Membrane Antigens (GMMA) by Genetic Lipid A Modifications
inferred← citeshttps://doi.org/10.1080/19490976.2016.1239682openalex-snapshot
The synthesis of OspD3 (ShET2) inShigella flexneriis independent of OspC1
inferred← citeshttps://doi.org/10.1080/19490976.2020.1770666openalex-snapshot
Vaccines against gastroenteritis, current progress and challenges
inferred← citeshttps://doi.org/10.1080/19490976.2020.1795389openalex-snapshot
Research in a time of enteroids and organoids: how the human gut model has transformed the study of enteric bacterial pathogens
inferred← citeshttps://doi.org/10.1080/21505594.2023.2280838openalex-snapshot
Pathogenicity and virulence of Shigella sonnei : A highly drug-resistant pathogen of increasing prevalence
inferred← citeshttps://doi.org/10.1080/21645515.2019.1575165openalex-snapshot
A phase I trial of WRSS1, a Shigella sonnei live oral vaccine in Bangladeshi adults and children
inferred← citeshttps://doi.org/10.1080/21645515.2019.1578922openalex-snapshot
A roadmap for enterotoxigenic Escherichia coli vaccine development based on volunteer challenge studies
inferred← citeshttps://doi.org/10.1080/21645515.2019.1606971openalex-snapshot
Serum IgG antibodies to Shigella lipopolysaccharide antigens – a correlate of protection against shigellosis
inferred← citeshttps://doi.org/10.1080/21645515.2019.1606972openalex-snapshot
Classical and novel strategies to develop a Shigella glycoconjugate vaccine: from concept to efficacy in human
inferred← citeshttps://doi.org/10.1080/21645515.2025.2603736openalex-snapshot
Shigella sonnei and Shigella flexneri : Epidemiology supporting development of cross-protective vaccines
inferred← citeshttps://doi.org/10.1089/mdr.2016.0173openalex-snapshot
Genomic Analysis and Resistance Mechanisms in Shigella flexneri 2a Strain 301
inferred← citeshttps://doi.org/10.1093/cid/ciaa1545openalex-snapshot
The Clinical Presentation of Culture-positive and Culture-negative, Quantitative Polymerase Chain Reaction (qPCR)-Attributable Shigellosis in the Global Enteric Multicenter Study and Derivation of a Shigella Severity Score: Implications for Pediatric Shigella Vaccine Trials
inferred← citeshttps://doi.org/10.1093/cid/ciac969openalex-snapshot
Shigella in Africa: New Insights From the Vaccine Impact on Diarrhea in Africa (VIDA) Study
inferred← citeshttps://doi.org/10.1093/cid/ciu471openalex-snapshot
Editorial Commentary: A Shigella Vaccine Against Prevalent Serotypes
inferred← citeshttps://doi.org/10.1093/cid/ciz892openalex-snapshot
Consensus Report on Shigella Controlled Human Infection Model: Conduct of Studies
inferred← citeshttps://doi.org/10.1093/femsle/fnac020openalex-snapshot
Bacteriophage Sf6 host range mutant that infects Shigella flexneri serotype 2a2 strains
inferred← citeshttps://doi.org/10.1093/femspd/ftw027openalex-snapshot
Genome diversity of Shigella boydii
inferred← citeshttps://doi.org/10.1093/femspd/ftw034openalex-snapshot
Characterization of a multicomponent live, attenuatedShigella flexnerivaccine
inferred← citeshttps://doi.org/10.1093/femspd/ftw098openalex-snapshot
Stable expression ofShigella dysenteriaeserotype 1 O-antigen genes integrated into the chromosome of liveSalmonellaoral vaccine vector Ty21a
inferred← citeshttps://doi.org/10.1093/glycob/cwv077openalex-snapshot
Purification and characterization of aShigellaconjugate vaccine, produced by glycoengineeringEscherichia coli
inferred← citeshttps://doi.org/10.1093/glycob/cwz044openalex-snapshot
Characterization and immunogenicity of a Shigella flexneri 2a O-antigen bioconjugate vaccine candidate
inferred← citeshttps://doi.org/10.1093/infdis/jiab462openalex-snapshot
Critical Needs in Advancing Shigella Vaccines for Global Health
inferred← citeshttps://doi.org/10.1093/infdis/jiag221openalex-snapshot
Shigella Vaccines: A Light at the End of a Long Tunnel
inferred← citeshttps://doi.org/10.1093/infdis/jiw528openalex-snapshot
Development of a live attenuated bivalent oral vaccine against Shigella sonnei shigellosis and typhoid fever
inferred← citeshttps://doi.org/10.1093/infdis/jiz220openalex-snapshot
Novel Insights Into the Spread of Enteric Pathogens Using Genomics
inferred← citeshttps://doi.org/10.1093/jpids/piv037openalex-snapshot
Failure of Syndrome-Based Diarrhea Management Guidelines to DetectShigellaInfections in Kenyan Children
inferred← citeshttps://doi.org/10.1093/jtm/taac132openalex-snapshot
Burden of Shigella in South Asia: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1093/jtm/tay049openalex-snapshot
Is a Shigella vaccine needed for travellers and the military?
inferred← citeshttps://doi.org/10.1093/lambio/ovac049openalex-snapshot
A novel strain of Shigella isolated from the gut of Lepidocephalichthys guntea has in its genome a complete gene package for Type ll secretion system, and elaborate repertoire of genes responsible for multiple antibiotic-resistance and metal resistance via specific efflux channels
inferred← citeshttps://doi.org/10.1093/ofid/ofad041openalex-snapshot
Salmonella Combination Vaccines: Moving Beyond Typhoid
inferred← citeshttps://doi.org/10.1093/ofid/ofad574openalex-snapshot
Shigella Detection and Molecular Serotyping With a Customized TaqMan Array Card in the Enterics for Global Health (EFGH): Shigella Surveillance Study
inferred← citeshttps://doi.org/10.1093/ofid/ofad576openalex-snapshot
Microbiological Methods Used in the Enterics for Global Health Shigella Surveillance Study
inferred← citeshttps://doi.org/10.1093/ofid/ofad653openalex-snapshot
The Enterics for Global Health (EFGH) Shigella Surveillance Study in Bangladesh
inferred← citeshttps://doi.org/10.1093/ofid/ofad654openalex-snapshot
The Enterics for Global Health (EFGH) Shigella Surveillance Study in Kenya
inferred← citeshttps://doi.org/10.1093/ofid/ofad664openalex-snapshot
Diarrhea Case Surveillance in the Enterics for Global Health Shigella Surveillance Study: Epidemiologic Methods
inferred← citeshttps://doi.org/10.1093/ofid/ofae003openalex-snapshot
The Enterics for Global Health (EFGH) Shigella Surveillance Study in Mali
inferred← citeshttps://doi.org/10.1093/ofid/ofae675openalex-snapshot
Development and Characterization of a 13-Plex Binding Assay to Detect Shigella Antibodies in Human Samples
inferred← citeshttps://doi.org/10.1093/ofid/ofaf026openalex-snapshot
Shigellosis in an Urban Slum in Kenya: Risk Factors and Antimicrobial Resistance
inferred← citeshttps://doi.org/10.1093/ofid/ofv134openalex-snapshot
Stx-Producing Shigella Species From Patients in Haiti: An Emerging Pathogen With the Potential for Global Spread
inferred← citeshttps://doi.org/10.1093/trstmh/tru175openalex-snapshot
Molecular characterization of Shigella spp. from patients in Gabon 2011-2013
inferred← citeshttps://doi.org/10.1097/mog.0000000000000133openalex-snapshot
An update on travelers’ diarrhea
inferred← citeshttps://doi.org/10.1097/mog.0000000000000136openalex-snapshot
Update on molecular epidemiology of Shigella infection
inferred← citeshttps://doi.org/10.1097/qco.0000000000000475openalex-snapshot
Recent insights into Shigella: a major contributor to the global diarrhoeal disease burden
inferred← citeshttps://doi.org/10.1097/qco.0000000000000758openalex-snapshot
Shigellosis in young children in low-income and middle-income countries: insights from molecular diagnostics
inferred← citeshttps://doi.org/10.1099/jmm.0.000779openalex-snapshot
Antimicrobial resistance profiles of Shigella dysenteriae isolated from travellers returning to the UK, 2004–2017
inferred← citeshttps://doi.org/10.1099/mgen.0.000311openalex-snapshot
Use of whole-genome sequencing to identify clusters of Shigella flexneri associated with sexual transmission in men who have sex with men in England: a validation study using linked behavioural data
inferred← citeshttps://doi.org/10.1099/mgen.0.000532openalex-snapshot
Whole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
inferred← citeshttps://doi.org/10.1099/mgen.0.000704openalex-snapshot
Cluster-specific gene markers enhance Shigella and enteroinvasive Escherichia coli in silico serotyping
inferred← citeshttps://doi.org/10.1099/mgen.0.000736openalex-snapshot
The evolutionary history of Shigella flexneri serotype 6 in Asia
inferred← citeshttps://doi.org/10.1099/mgen.0.000846openalex-snapshot
Virulence plasmid pINV as a genetic signature for Shigella flexneri phylogeny
inferred← citeshttps://doi.org/10.1099/mgen.0.001157openalex-snapshot
Genomic analysis of Shigella isolates from Lebanon reveals marked genetic diversity and antimicrobial resistance
inferred← citeshttps://doi.org/10.1099/mgen.0.001838openalex-snapshot
Genomic epidemiology and antimicrobial resistance profile of Shigella isolated from diarrhoea diseases in under-five children in Blantyre, Malawi
inferred← citeshttps://doi.org/10.1101/2020.08.10.243006openalex-snapshot
The role of toxin:antitoxin systems and insertion sequences in the loss of virulence in Shigella sonnei
inferred← citeshttps://doi.org/10.1101/2021.03.09.434519openalex-snapshot
A comprehensive computational investigation into the conserved virulent proteins of Shigella sp unveils potential siRNA candidates as a new therapeutic strategy against shigellosis
inferred← citeshttps://doi.org/10.1101/2021.06.09.447709openalex-snapshot
Informing shigellosis prevention and control through pathogen genomics
inferred← citeshttps://doi.org/10.1101/2022.08.23.504947openalex-snapshot
Temporal GWAS identifies a widely distributed novel protein Stv contributing to pathogen success in Shigella spp
inferred← citeshttps://doi.org/10.1101/2022.09.26.22280249openalex-snapshot
Epidemiology and risk factors for diarrhoeagenic Escherichia coli carriage among children in northern Ibadan, Nigeria
inferred← citeshttps://doi.org/10.1101/2023.07.03.23292159openalex-snapshot
Burden of diarrhea and antibiotic use among children in low-resource settings preventable by Shigella vaccination: a simulation study
inferred← citeshttps://doi.org/10.1101/2023.08.24.554604openalex-snapshot
Targeted lipid A modification of Shigella vaccine strains reduced endotoxicity without compromising immunogenicity or invasiveness
inferred← citeshttps://doi.org/10.1101/2025.08.10.25333393openalex-snapshot
Population-based incidence and antimicrobial susceptibility patterns of shigellosis among children and adults from rural and urban Kenya, 2010-2019
inferred← citeshttps://doi.org/10.1101/799379openalex-snapshot
Shigella sonnei O-antigen inhibits internalisation, vacuole escape and inflammasome activation
inferred← citeshttps://doi.org/10.1111/1753-6405.12844openalex-snapshot
Culture‐positive shigellosis cases are epidemiologically different to culture‐negative/PCR‐positive cases
inferred← citeshttps://doi.org/10.1111/cmi.13067openalex-snapshot
A tale of two bacterial enteropathogens and one multivalent vaccine
inferred← citeshttps://doi.org/10.1111/cts.70453openalex-snapshot
Population Pharmacokinetic and Pharmacodynamic Prediction for Tebipenem Pivoxil Treatment of Pediatric Shigellosis
inferred← citeshttps://doi.org/10.1111/jam.15383openalex-snapshot
Development of a loop-mediated isothermal amplification assay for molecular serotyping of Shigella flexneri Serotypes 2 and Xv
inferred← citeshttps://doi.org/10.1111/lam.12690openalex-snapshot
Update on: Shigella new serogroups/serotypes and their antimicrobial resistance
inferred← citeshttps://doi.org/10.1111/tmi.13445openalex-snapshot
Pathogen‐specific risk of seizure in children with moderate‐to‐severe diarrhoea: Case control study with follow‐up
inferred← citeshttps://doi.org/10.1128/aem.00165-19openalex-snapshot
In Silico Serotyping Based on Whole-Genome Sequencing Improves the Accuracy of Shigella Identification
inferred← citeshttps://doi.org/10.1128/cmr.00008-21openalex-snapshot
Controlled Human Infection Models To Accelerate Vaccine Development
inferred← citeshttps://doi.org/10.1128/cvi.00148-16openalex-snapshot
Monoclonal Antibodies to Shigella Lipopolysaccharide Are Useful for Vaccine Production
inferred← citeshttps://doi.org/10.1128/cvi.00181-17openalex-snapshot
Stable Chromosomal Expression of Shigella flexneri 2a and 3a O-Antigens in the Live Salmonella Oral Vaccine Vector Ty21a
inferred← citeshttps://doi.org/10.1128/cvi.00224-16openalex-snapshot
Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study
inferred← citeshttps://doi.org/10.1128/cvi.00444-16openalex-snapshot
Shigella Vaccine Development: Finding the Path of Least Resistance
inferred← citeshttps://doi.org/10.1128/cvi.00608-15openalex-snapshot
Evaluation of the Safety, Tolerability, and Immunogenicity of an Oral, Inactivated Whole-Cell Shigella flexneri 2a Vaccine in Healthy Adult Subjects
inferred← citeshttps://doi.org/10.1128/cvi.00661-14openalex-snapshot
Shigella Outer Membrane Protein PSSP-1 Is Broadly Protective against Shigella Infection
inferred← citeshttps://doi.org/10.1128/ecosalplus.esp-0006-2017openalex-snapshot
A Brief History of Shigella
inferred← citeshttps://doi.org/10.1128/genomea.00393-15openalex-snapshot
Draft Genome Sequence of 24570, the Type Strain of Shigella flexneri
inferred← citeshttps://doi.org/10.1128/iai.00004-25openalex-snapshot
Immunogenicity and preclinical efficacy characterization of ShecVax, a combined vaccine against Shigella and enterotoxigenic Escherichia coli
inferred← citeshttps://doi.org/10.1128/iai.00316-23openalex-snapshot
A broadly immunogenic polyvalent Shigella multiepitope fusion antigen protein protects against Shigella sonnei and Shigella flexneri lethal pulmonary challenges in mice
inferred← citeshttps://doi.org/10.1128/iai.00665-25openalex-snapshot
Lithocholic acid induces T3SS-dependent formation of invasion-competent Shigella flexneri aggregates
inferred← citeshttps://doi.org/10.1128/iai.00740-18openalex-snapshot
Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model
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