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‘RE:fine drugs’: an interactive dashboard to access drug repurposing opportunities

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/wsbm.147openalex-snapshot

Drug repurposing and adverse event prediction using high‐throughput literature analysis

inferredcites →https://doi.org/10.1016/j.drudis.2012.06.015openalex-snapshot

Opportunities in systems biology to discover mechanisms and repurpose drugs for CNS diseases

inferredcites →https://doi.org/10.1016/j.drudis.2013.11.005openalex-snapshot

Toward better drug repositioning: prioritizing and integrating existing methods into efficient pipelines

inferredcites →https://doi.org/10.1016/j.jclinepi.2006.01.012openalex-snapshot

Testing multiple statistical hypotheses resulted in spurious associations: a study of astrological signs and health

inferredcites →https://doi.org/10.1016/j.tips.2013.03.004openalex-snapshot

Challenges and opportunities of drug repositioning

inferredcites →https://doi.org/10.1021/ci100369fopenalex-snapshot

A Machine Learning-Based Method To Improve Docking Scoring Functions and Its Application to Drug Repurposing

inferredcites →https://doi.org/10.1038/clpt.2013.1openalex-snapshot

Computational Drug Repositioning: From Data to Therapeutics

inferredcites →https://doi.org/10.1038/nbt.2151openalex-snapshot

Use of genome-wide association studies for drug repositioning

inferredcites →https://doi.org/10.1038/nbt.2749openalex-snapshot

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

inferredcites →https://doi.org/10.1038/nbt.3183openalex-snapshot

Opportunities for drug repositioning from phenome-wide association studies

inferredcites →https://doi.org/10.1038/ng.3314openalex-snapshot

The support of human genetic evidence for approved drug indications

inferredcites →https://doi.org/10.1038/nrd1468openalex-snapshot

Drug repositioning: identifying and developing new uses for existing drugs

inferredcites →https://doi.org/10.1093/bioinformatics/bts186openalex-snapshot

e-Drug3D: 3D structure collections dedicated to drug repurposing and fragment-based drug design

inferredcites →https://doi.org/10.1093/bioinformatics/btt279openalex-snapshot

DrugMap Central: an on-line query and visualization tool to facilitate drug repositioning studies

inferredcites →https://doi.org/10.1093/nar/gkq1037openalex-snapshot

PROMISCUOUS: a database for network-based drug-repositioning

inferredcites →https://doi.org/10.1093/nar/gkr299openalex-snapshot

DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome

inferredcites →https://doi.org/10.1093/nar/gkt1068openalex-snapshot

DrugBank 4.0: shedding new light on drug metabolism

inferredcites →https://doi.org/10.1111/j.1523-1739.2005.00269.xopenalex-snapshot

Judicious Use of Multiple Hypothesis Tests

inferredcites →https://doi.org/10.1186/1471-2105-10-s5-s4openalex-snapshot

Inferring novel disease indications for known drugs by semantically linking drug action and disease mechanism relationships

inferredcites →https://doi.org/10.1186/1752-0509-6-80openalex-snapshot

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug

inferredcites →https://doi.org/10.1186/1755-8794-6-s2-s3openalex-snapshot

Compensating for literature annotation bias when predicting novel drug-disease relationships through Medical Subject Heading Over-representation Profile (MeSHOP) similarity

inferredcites →https://doi.org/10.1186/2049-6958-10-1openalex-snapshot

Tailored therapy for severe asthma

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Estimating The Cost Of New Drug Development: Is It Really $802 Million?

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Daclizumab a novel corticosteroid-sparing therapy for asthma?

inferredcites →https://doi.org/10.5860/choice.41-6569openalex-snapshot

Drugs: from discovery to approval

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/ddr.70270openalex-snapshot

Blueprint for Drug Repurposing Success: Foundational Concepts and Practical Framework

inferred← citeshttps://doi.org/10.1002/med.21627openalex-snapshot

Repurposing approved drugs on the pathway to novel therapies

inferred← citeshttps://doi.org/10.1007/978-3-030-45385-5_20openalex-snapshot

Computational Approaches for Drug Design: A Focus on Drug Repurposing

inferred← citeshttps://doi.org/10.1007/978-3-030-91836-1_7openalex-snapshot

Computational Methods for Drug Repurposing

inferred← citeshttps://doi.org/10.1007/978-981-16-0753-0_4openalex-snapshot

Common Network Pharmacology Software

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Text mining-based in silico drug discovery in oral mucositis caused by high-dose cancer therapy

inferred← citeshttps://doi.org/10.1016/b978-0-12-801917-7.00066-8openalex-snapshot

Repositioning Drugs for Systemic Lupus Erythematosus

inferred← citeshttps://doi.org/10.1016/b978-0-12-809633-8.20160-xopenalex-snapshot

Drug Repurposing and Multi-Target Therapies

inferred← citeshttps://doi.org/10.1016/b978-0-12-814551-7.00067-2openalex-snapshot

Repositioning drugs for systemic lupus erythematosus

inferred← citeshttps://doi.org/10.1016/b978-0-12-816125-8.00015-8openalex-snapshot

Application of In Silico Drug Repurposing in Infectious Diseases

inferred← citeshttps://doi.org/10.1016/b978-0-12-816125-8.00024-9openalex-snapshot

In Silico Databases and Tools for Drug Repurposing

inferred← citeshttps://doi.org/10.1016/b978-0-12-816125-8.00027-4openalex-snapshot

Drug Repositioning Strategies to Explore New Candidates Treating Prostate Cancer

inferred← citeshttps://doi.org/10.1016/j.arcmed.2020.10.021openalex-snapshot

Drug Repurposing: Considerations to Surpass While Re-directing Old Compounds for New Treatments

inferred← citeshttps://doi.org/10.1016/j.coisb.2017.04.010openalex-snapshot

Drug repositioning beyond the low-hanging fruits

inferred← citeshttps://doi.org/10.1016/j.hsr.2024.100194openalex-snapshot

Unravelling the genomic maze: Bioinformatics unleashes insights into Sotos syndrome (Cerebral Gigantism)

inferred← citeshttps://doi.org/10.1016/j.phrs.2025.107953openalex-snapshot

Intelligent technology leads the transformation of traditional Chinese medicine: Large models and virtual cells aid modern analysis of stroke treatment

inferred← citeshttps://doi.org/10.1016/j.rdc.2017.04.010openalex-snapshot

Drug Repositioning Strategies for the Identification of Novel Therapies for Rheumatic Autoimmune Inflammatory Diseases

inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.09.020openalex-snapshot

Systems biology based drug repositioning for development of cancer therapy

inferred← citeshttps://doi.org/10.1038/s41366-025-01898-zopenalex-snapshot

Integrating genetic and transcriptomic data to identify genes underlying obesity risk loci

inferred← citeshttps://doi.org/10.1038/s41525-022-00290-4openalex-snapshot

The druggable schizophrenia genome: from repurposing opportunities to unexplored drug targets

inferred← citeshttps://doi.org/10.1038/s41584-019-0337-0openalex-snapshot

Drug repurposing to improve treatment of rheumatic autoimmune inflammatory diseases

inferred← citeshttps://doi.org/10.1038/s41591-019-0722-xopenalex-snapshot

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas

inferred← citeshttps://doi.org/10.1038/s41596-020-00430-zopenalex-snapshot

OCTAD: an open workspace for virtually screening therapeutics targeting precise cancer patient groups using gene expression features

inferred← citeshttps://doi.org/10.1063/5.0177016openalex-snapshot

An improved approaches for novel mining serendipitous drug to generate and validate drug repositioning hypotheses from social media comparing with Adaboost algorithm

inferred← citeshttps://doi.org/10.1089/omi.2017.0127openalex-snapshot

Transcriptomic-Guided Drug Repositioning Supported by a New Bioinformatics Search Tool: geneXpharma

inferred← citeshttps://doi.org/10.1089/omi.2021.0221openalex-snapshot

Past, Present, and Future of Therapies for Pituitary Neuroendocrine Tumors: Need for Omics and Drug Repositioning Guidance

inferred← citeshttps://doi.org/10.1093/bib/bbad527openalex-snapshot

The landscape of the methodology in drug repurposing using human genomic data: a systematic review

inferred← citeshttps://doi.org/10.1093/bib/bbx125openalex-snapshot

Web-based drug repurposing tools: a survey

inferred← citeshttps://doi.org/10.1097/prs.0000000000010350openalex-snapshot

Identification of Drug Compounds for Capsular Contracture Based on Text Mining and Deep Learning

inferred← citeshttps://doi.org/10.1101/2020.11.27.368811openalex-snapshot

Biomedical Graph Visualizer for Identifying Drug Candidates

inferred← citeshttps://doi.org/10.1109/ichi69079.2026.00089openalex-snapshot

RePurposeX: Designing Mixed-Initiative Decision Support for Drug Repurposing with Biomedical Knowledge Graphs

inferred← citeshttps://doi.org/10.1111/bph.13798openalex-snapshot

Drug repurposing from the perspective of pharmaceutical companies

inferred← citeshttps://doi.org/10.1111/cts.12522openalex-snapshot

Genome‐wide and Phenome‐wide Approaches to Understand Variable Drug Actions in Electronic Health Records

inferred← citeshttps://doi.org/10.1111/dmcn.14822openalex-snapshot

Fenfluramine as antiseizure medication for epilepsy

inferred← citeshttps://doi.org/10.1145/2975167.2975197openalex-snapshot

Prioritizing Adverse Drug Reaction and Drug Repositioning Candidates Generated by Literature-Based Discovery

inferred← citeshttps://doi.org/10.1155/2021/6674744openalex-snapshot

Text Mining-Based Drug Discovery in Osteoarthritis

inferred← citeshttps://doi.org/10.1186/s12920-022-01370-1openalex-snapshot

Identification of core genes and pathways between geriatric multimorbidity and renal insufficiency: potential therapeutic agents discovered using bioinformatics analysis

inferred← citeshttps://doi.org/10.1186/s40246-019-0239-xopenalex-snapshot

Identification of key candidate genes and molecular pathways in white fat browning: an anti-obesity drug discovery based on computational biology

inferred← citeshttps://doi.org/10.1371/journal.pone.0309594openalex-snapshot

Identification of pivotal genes and pathways in Chorea-acanthocytosis using comprehensive bioinformatic analysis

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Text Mining-Based Drug Discovery and MAPK14, STAT3, VEGFA as Novel Candidate Genes in Post-Tuberculosis Tracheobronchial Stenosis

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Integrating Network Pharmacology and Experimental Evaluation of Ocimum tenuiflorum (Tulsi) compounds targeting Breast Cancer Markers

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Drug discovery in rheumatoid arthritis with joint effusion identified by text mining and biomedical databases

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Identification of drug compounds for keloids and hypertrophic scars: drug discovery based on text mining and DeepPurpose

inferred← citeshttps://doi.org/10.2174/0929867327666200128111925openalex-snapshot

Web-based Tools for Drug Repurposing: Successful Examples of Collaborative Research

inferred← citeshttps://doi.org/10.2196/resprot.5621openalex-snapshot

Using Social Media Data to Identify Potential Candidates for Drug Repurposing: A Feasibility Study

inferred← citeshttps://doi.org/10.22092/ari.2021.356195.1800openalex-snapshot

Effects of Apremilast on Induced Hypertrophic Scar of Rabbits.

inferred← citeshttps://doi.org/10.31083/j.ceog4908168openalex-snapshot

Computational Drug Discovery in Patients with Endometriosis-Induced Infertility via Text Mining and Biomedical Databases

inferred← citeshttps://doi.org/10.3389/fgene.2022.868015openalex-snapshot

StarGazer: A Hybrid Intelligence Platform for Drug Target Prioritization and Digital Drug Repositioning Using Streamlit

inferred← citeshttps://doi.org/10.3389/fphar.2017.00896openalex-snapshot

Enhancing the Promise of Drug Repositioning through Genetics

inferred← citeshttps://doi.org/10.3389/fphar.2022.743210openalex-snapshot

Text Mining-Based Drug Discovery for Connective Tissue Disease–Associated Pulmonary Arterial Hypertension

inferred← citeshttps://doi.org/10.3389/fphar.2022.933655openalex-snapshot

Disulfiram in glioma: Literature review of drug repurposing

inferred← citeshttps://doi.org/10.35631/ijlgc.729020openalex-snapshot

DASHBOARD AS AN ALTERNATIVE TO VISUALIZE INTEGRITY OF STAFF

inferred← citeshttps://doi.org/10.3791/54948openalex-snapshot

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

inferred← citeshttps://doi.org/10.3791/54948-vopenalex-snapshot

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

inferred← citeshttps://doi.org/10.3892/or.2018.6746openalex-snapshot

Text mining‑based drug discovery in cutaneous squamous cell carcinoma

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Bioinformatics Analysis Identifies Potential Hub Genes, Therapeutic Agents, and Crucial Pathways in the Pathogenesis of Refsum's Disease

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Identification of key genes and pathways in scleral extracellular matrix remodeling in glaucoma: Potential therapeutic agents discovered using bioinformatics analysis

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