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Noncoding Variation and Transcriptional Plasticity Promote Thermal Adaptation in Oysters by Altering Energy Metabolism

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Temperature, energy metabolism, and adaptive divergence in two oyster subspecies
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Population Genomics Reveal Recent Speciation and Rapid Evolutionary Adaptation in Polar Bears
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Immune and stress responses in oysters with insights on adaptation
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The oyster genome reveals stress adaptation and complexity of shell formation
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Non-adaptive plasticity potentiates rapid adaptive evolution of gene expression in nature
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Oyster reproduction is affected by exposure to polystyrene microplastics
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Fast and accurate short read alignment with Burrows–Wheeler transform
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The variant call format and VCFtools
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Can a Network Approach Resolve How Adaptive vs Nonadaptive Plasticity Impacts Evolutionary Trajectories?
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Plastic and Evolutionary Gene Expression Responses Are Correlated in European Grayling (Thymallus thymallus) Subpopulations Adapted to Different Thermal Environments
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Evolutionary trade-offs between baseline and plastic gene expression in two congeneric oyster species
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Adaptation to heat stress reduces phenotypic and transcriptional plasticity in a marine copepod
inferredcites →https://doi.org/10.1111/1755-0998.13368openalex-snapshot
Construction of a chromosome‐level genome and variation map for the Pacific oyster Crassostrea gigas
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Selection on oxidative phosphorylation and ribosomal structure as a multigenerational response to ocean acidification in the common copepod Pseudocalanus acuspes
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Climate change and evolution: disentangling environmental and genetic responses
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GENETIC ASSIMILATION OF AN ACQUIRED CHARACTER
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ESTIMATING F -STATISTICS FOR THE ANALYSIS OF POPULATION STRUCTURE
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THE BALDWIN EFFECT AND GENETIC ASSIMILATION: REVISITING TWO MECHANISMS OF EVOLUTIONARY CHANGE MEDIATED BY PHENOTYPIC PLASTICITY
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Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
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Gene expression under chronic heat stress in populations of the mustard hill coral ( P orites astreoides) from different thermal environments
inferredcites →https://doi.org/10.1146/annurev-animal-022114-110903openalex-snapshot
Molecular Basis for Adaptation of Oysters to Stressful Marine Intertidal Environments
inferredcites →https://doi.org/10.1146/annurev-marine-120709-142756openalex-snapshot
Local Adaptation in Marine Invertebrates
inferredcites →https://doi.org/10.1146/annurev-marine-120710-100935openalex-snapshot
The Physiology of Global Change: Linking Patterns to Mechanisms
inferredcites →https://doi.org/10.1186/1471-2105-14-289openalex-snapshot
Calculation of Tajima’s D and other neutrality test statistics from low depth next-generation sequencing data
inferredcites →https://doi.org/10.1186/1471-2105-9-559openalex-snapshot
WGCNA: an R package for weighted correlation network analysis
inferredcites →https://doi.org/10.1186/1471-2148-10-394openalex-snapshot
Unusual conservation of mitochondrial gene order in Crassostreaoysters: evidence for recent speciation in Asia
inferredcites →https://doi.org/10.1186/1471-2156-11-94openalex-snapshot
Discriminant analysis of principal components: a new method for the analysis of genetically structured populations
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1194/jlr.m400039-jlr200openalex-snapshot
Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment
inferredcites →https://doi.org/10.1201/b10201-2openalex-snapshot
What is Phenotypic Plasticity and Why is it Important?
inferredcites →https://doi.org/10.1242/jeb.118851openalex-snapshot
The effects of temperature on aerobic metabolism: towards a mechanistic understanding of the responses of ectotherms to a changing environment
inferredcites →https://doi.org/10.1371/journal.pbio.1000357openalex-snapshot
Adaptation, Plasticity, and Extinction in a Changing Environment: Towards a Predictive Theory
inferredcites →https://doi.org/10.1371/journal.pone.0030619openalex-snapshot
NGS QC Toolkit: A Toolkit for Quality Control of Next Generation Sequencing Data
inferredcites →https://doi.org/10.1534/g3.116.026971openalex-snapshot
A High-Density SNP Genetic Linkage Map and QTL Analysis of Growth-Related Traits in a Hybrid Family of Oysters ( Crassostrea gigas × Crassostrea angulata ) Using Genotyping-by-Sequencing
inferredcites →https://doi.org/10.1534/genetics.113.154740openalex-snapshot
Quantifying Population Genetic Differentiation from Next-Generation Sequencing Data
inferredcites →https://doi.org/10.1890/03-0788openalex-snapshot
EVOLUTIONARY RESPONSES TO CHANGING CLIMATE
inferredcites →https://doi.org/10.2983/035.029.0420openalex-snapshot
Classification of a Common Cupped Oyster from Southern China
inferredcites →https://doi.org/10.2983/035.037.0407openalex-snapshot
Diversity and Evolution of Living Oysters
inferredcites →https://doi.org/10.2983/0730-8000(2008)27[495:cocofn]2.0.co;2openalex-snapshot
Classification of Common Oysters from North China
inferredcites →https://doi.org/10.3389/fphys.2018.00825openalex-snapshot
Transcriptomics and Fitness Data Reveal Adaptive Plasticity of Thermal Tolerance in Oysters Inhabiting Different Tidal Zones
inferredcites →https://doi.org/10.3389/fphys.2019.01137openalex-snapshot
Thermotolerance Divergence Revealed by the Physiological and Molecular Responses in Two Oyster Subspecies of Crassostrea gigas in China
inferredcites →https://doi.org/10.4161/fly.19695openalex-snapshot
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4799771openalex-extracted
MAPK/ERK Phosphorylates Conserved PK Ser11 Site in Mollusk Regulates Divergent Thermal Metabolism of Two Congeneric Oyster Species
inferred← citeshttps://doi.org/10.1002/pro.4362openalex-snapshot
Mechanisms of protein evolution
inferred← citeshttps://doi.org/10.1007/s10126-022-10140-0openalex-snapshot
Genome-Wide Identification of Long Non-coding RNAs in Crassostrea gigas and Their Association with Heat Stress
inferred← citeshttps://doi.org/10.1007/s10126-023-10231-6openalex-snapshot
Contribution of HIF-1α to Heat Shock Response by Transcriptional Regulation of HSF1/HSP70 Signaling Pathway in Pacific Oyster, Crassostrea gigas
inferred← citeshttps://doi.org/10.1007/s10126-025-10539-5openalex-snapshot
A Transcription Factor-based Framework for Monitoring Stress Status in Oysters: Applications in Conservation and Restoration
inferred← citeshttps://doi.org/10.1007/s10126-026-10643-0openalex-snapshot
Stearoyl-CoA Desaturase (SCD) Gene Based Molecular Breeding Enhances Nutritional Quality and Growth Performance in the Oyster (Crassostrea angulata)
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Cis-variation–trans-variation interactions between Hsp90 promoters shape G × E effects and underlie divergent phenotypic thermal adaptation plasticity in two congeneric oyster species
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2022.739214openalex-snapshot
Accelerated energy metabolism plays an important role in Heterosis and maternal effect of hybrids bred from southern and northern Suminoe oysters (Crassostrea ariakensis)
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2023.740177openalex-snapshot
Comparative chromatin dynamics reveal differential thermal tolerance mechanisms between two congeneric oyster species
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2024.741475openalex-snapshot
Genome-wide characterization of histone gene family in Pacific oyster (Crassostrea gigas) and expression analysis under environmental stresses
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2024.741929openalex-snapshot
Physiological and genomic comparisons revealed the selective breeding improved the oceanic-salinity adaptability of estuarine oysters (Crassostrea ariakensis)
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2025.742331openalex-snapshot
The improved heat tolerance and underlying mechanism for the selected backcross population from the Crassostrea gigas with Crassostrea angulata
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2025.742855openalex-snapshot
MAPK/ERK-driven transcriptional regulation mediates divergent thermal tolerance in two congeneric oyster species
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2025.743404openalex-snapshot
Comparative transcriptomic and metabolomic analyses reveal different tolerance mechanisms to heat stress in two geographic populations of Argopecten irradians concentricus
inferred← citeshttps://doi.org/10.1016/j.cbd.2025.101479openalex-snapshot
Clam age constrains thermal tolerance: Insights from burrowing behavior and transcriptomics
inferred← citeshttps://doi.org/10.1016/j.cbd.2026.101875openalex-snapshot
Epitranscriptomic erasers in bivalves: Evolutionary divergence and species-specific transcriptional plasticity of the ALKBH family under acute thermal stress
inferred← citeshttps://doi.org/10.1016/j.cbd.2026.101913openalex-snapshot
Comparative analysis of genomic variations among different Cdo1 paralogs for salinity-adaptation in oysters
inferred← citeshttps://doi.org/10.1016/j.cbd.2026.102039openalex-snapshot
Transcriptome and metabolome integration reveals molecular mechanisms underlying divergent cold tolerance in geographically distinct Procambarus clarkii populations
inferred← citeshttps://doi.org/10.1016/j.cbpb.2025.111101openalex-snapshot
Regulatory variants of glycogen synthase contribute to differential glycogen content between Crassostrea gigas and C. sikamea
inferred← citeshttps://doi.org/10.1016/j.coisb.2023.100479openalex-snapshot
Robustness of microbiome function
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2023.115197openalex-snapshot
Comparative proteomic and phosphoproteomic analysis reveals differential heat response mechanism in two congeneric oyster species
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.118210openalex-snapshot
Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas)
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.119164openalex-snapshot
Divergence of underlying mechanisms in response to alkalinity conditions between two crucian carp (Carassius auratus) populations
inferred← citeshttps://doi.org/10.1016/j.envpol.2023.122101openalex-snapshot
Differentiation and decreased genetic diversity in field contaminated oysters Crassostrea hongkongensis: Identification of selection signatures
inferred← citeshttps://doi.org/10.1016/j.envpol.2025.126411openalex-snapshot
Biomineralization mechanisms in the estuarine oyster (Crassostrea ariakensis): Unveiling the adaptive potential of mollusks in response to rapid climate change
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Genome-wide mapping of regulatory variants for temperature- and salinity-adaptive genes reveals genetic basis of genotype-by-environment interaction in Crassostrea ariakensis
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Tidal emersion effects on universal metrics, elemental contents, and health conditions of Pacific oyster (Crassostrea gigas) on artificial reefs in Yellow River Delta, China
inferred← citeshttps://doi.org/10.1016/j.gecco.2026.e04219openalex-snapshot
Species range evolution of the rocky intertidal leaf oyster Isognomon nucleus (Lamarck, 1819) in the Indo-Pacific
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.143183openalex-snapshot
Ctnnb1 and Keap1-Nrf2 mediating divergent heat resistance in two congeneric oysters
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.145808openalex-snapshot
Unravelling the regulatory network underlying divergent expression of the key lipid metabolism transcription factor SREBP in two congeneric oyster species
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2026.151949openalex-snapshot
Genome-wide identification and functional validation of thermal tolerance genes in Mytilus coruscus using a yeast-based functional screening system
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2026.153160openalex-snapshot
Identifying the regulatory network of the key lipid metabolism transcription factor peroxisome proliferator-activated receptor in oysters
inferred← citeshttps://doi.org/10.1016/j.isci.2024.110321openalex-snapshot
MAPK/ERK-PK(Ser11) pathway regulates divergent thermal metabolism of two congeneric oyster species
inferred← citeshttps://doi.org/10.1016/j.marenvres.2026.108249openalex-snapshot
Metabolic trade-offs shape acute thermal responses in the marine predator Rapana venosa
inferred← citeshttps://doi.org/10.1016/j.marpolbul.2021.112932openalex-snapshot
Impacts of marine heatwaves on pearl oysters are alleviated following repeated exposure
inferred← citeshttps://doi.org/10.1016/j.marpolbul.2024.117362openalex-snapshot
Behavioral responses of clams to recurrent marine heatwaves
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.151189openalex-snapshot
Transcriptome analysis reveals acclimation responses of pearl oysters to marine heatwaves
inferred← citeshttps://doi.org/10.1016/j.xinn.2023.100464openalex-snapshot
Genome architecture and selective signals compensatorily shape plastic response to a new environment
inferred← citeshttps://doi.org/10.1021/acs.est.4c07808openalex-snapshot
Low pH Means More Female Offspring: A Multigenerational Plasticity in the Sex Ratio of Marine Bivalves
inferred← citeshttps://doi.org/10.1038/s41597-024-04145-8openalex-snapshot
Chromosome-level genome assembly of the Suminoe oyster Crassostrea ariakensis in south China
inferred← citeshttps://doi.org/10.1038/s41597-025-05822-yopenalex-snapshot
Genetic Resources for Research on the Regulatory Mechanism of ω-3 Fatty Acids in Oysters
inferred← citeshttps://doi.org/10.1038/s42003-021-02823-6openalex-snapshot
Genome of the estuarine oyster provides insights into climate impact and adaptive plasticity
inferred← citeshttps://doi.org/10.1038/s42003-026-10054-wopenalex-snapshot
A naturally synonymous mutation modulates an ERK-centered regulatory network to mediate thermotolerance divergence in Crassostrea oysters
inferred← citeshttps://doi.org/10.1093/gigascience/giad077openalex-snapshot
Construction and analysis of the chromosome-level haplotype-resolved genomes of two Crassostrea oyster congeners: Crassostrea angulata and Crassostrea gigas
inferred← citeshttps://doi.org/10.1093/molbev/msad015openalex-snapshot
Cis - and Trans -variations of Stearoyl-CoA Desaturase Provide New Insights into the Mechanisms of Diverged Pattern of Phenotypic Plasticity for Temperature Adaptation in Two Congeneric Oyster Species
inferred← citeshttps://doi.org/10.1101/2024.07.01.601629openalex-snapshot
Genetic architecture of the thermal tolerance landscape of Drosophila melanogaster
inferred← citeshttps://doi.org/10.1111/1755-0998.13556openalex-snapshot
Chromosome‐level genome and population genomic analysis provide insights into the evolution and environmental adaptation of Jinjiang oysterCrassostrea ariakensis
inferred← citeshttps://doi.org/10.1111/eva.13551openalex-snapshot
Genome‐wide evolutionary signatures of climate adaptation in spotted sea bass inhabiting different latitudinal regions
inferred← citeshttps://doi.org/10.1111/eva.70156openalex-snapshot
Membrane Lipid Remodeling Strategies Regulate Fluidity for Acute Temperature Adaptation in Oysters
inferred← citeshttps://doi.org/10.1111/mec.16610openalex-snapshot
Demographic, physiological and genetic factors linked to the poleward range expansion of the snail Nerita yoldii along the shoreline of China
inferred← citeshttps://doi.org/10.1111/mec.17108openalex-snapshot
Parallel evolution in Crassostrea oysters along the latitudinal gradient is associated with variation in multiple genes involved in adipogenesis
inferred← citeshttps://doi.org/10.1111/mec.17623openalex-snapshot
Genotype‐by‐Environment Effects of Cis ‐Variations in the Atgl Promoter Mediate the Divergent Pattern of Phenotypic Plasticity for Temperature Adaptation in Two Congeneric Oyster Species
inferred← citeshttps://doi.org/10.1111/mec.17697openalex-snapshot
Genetic Architecture of the Thermal Tolerance Landscape in Drosophila melanogaster
inferred← citeshttps://doi.org/10.1111/mec.70013openalex-snapshot
Interplay of Multilayered Transcriptomic Plasticity in Response to Temperature Fluctuations During Biological Invasions: A Case Study in Invasive Styela plicata
inferred← citeshttps://doi.org/10.1111/mec.70236openalex-snapshot
Evolving Gene Expression Plasticity Under Climate Change: A Case Study of Thermal Adaptation in the Invasive Tunicate Herdmania momus
inferred← citeshttps://doi.org/10.1111/mec.70246openalex-snapshot
Plastic Responses and Standing Genetic Variation in Salinity‐Responsive Genes Under Projected Salinisation in Freshwater Fish
inferred← citeshttps://doi.org/10.1111/mec.70480openalex-snapshot
The Priming Impacts of Early Hypoxia Exposure in Abalone Parents Are Transmitted to Offspring
inferred← citeshttps://doi.org/10.1155/are/1073606openalex-snapshot
Genetic Differentiation and Adaptive Evolution Mechanisms of Cultured and Wild Spotted Sea Bass ( Lateolabrax maculatus ) Populations Based on a 40K SNP Liquid Array
inferred← citeshttps://doi.org/10.1186/s12864-022-09040-3openalex-snapshot
A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
inferred← citeshttps://doi.org/10.1186/s12864-025-12345-8openalex-snapshot
Independent divergences of the aquaporins across different genera highlight the distinct adaptation mechanisms within Mytilida
inferred← citeshttps://doi.org/10.2139/ssrn.5132244openalex-snapshot
Biomineralization Mechanisms in the Estuarine Oyster (Crassostrea Ariakensis): Unveiling the Adaptive Potential of Molluscs in Response to Rapid Climate Change
inferred← citeshttps://doi.org/10.2139/ssrn.6891372openalex-snapshot
Enzyme activity and gene expression reflect adaptive divergence in response to thermal stress in two congeneric oyster species
inferred← citeshttps://doi.org/10.22541/au.171828254.43240088/v1openalex-snapshot
Cis-variation Interacting with Trans-variation in Promoter Shaping G×E Effects of Hsp90 Underlies Divergent Phenotypic Plasticity for Thermal Adaptation in Two Congeneric Oyster Species
inferred← citeshttps://doi.org/10.3389/fmars.2021.744626openalex-snapshot
Integrated Application of Transcriptomics and Metabolomics Reveals the Energy Allocation-Mediated Mechanisms of Growth-Defense Trade-Offs in Crassostrea gigas and Crassostrea angulata
inferred← citeshttps://doi.org/10.3389/fmars.2022.1017142openalex-snapshot
High temperature induced metabolic reprogramming and lipid remodeling in a high-altitude fish species, Triplophysa bleekeri
inferred← citeshttps://doi.org/10.3389/fmars.2022.975686openalex-snapshot
Insights into adaptive divergence of Japanese mantis shrimp Oratosquilla oratoria inferred from comparative analysis of full-length transcriptomes
inferred← citeshttps://doi.org/10.3390/fishes11100572openalex-snapshot
Genetic Diversity Analysis of Meretrix meretrix Based on Reduced-Representation Genome Sequencing and Transcriptome Sequencing
inferred← citeshttps://doi.org/10.3390/ijms25010125openalex-snapshot
Genome-Wide Association Analysis of Heat Tolerance in F2 Progeny from the Hybridization between Two Congeneric Oyster Species
inferred← citeshttps://doi.org/10.3390/ijms252413551openalex-snapshot
Genetic Variants Affecting FADS2 Enzyme Dynamics and Gene Expression in Cogenetic Oysters with Different PUFA Levels Provide New Tools to Improve Unsaturated Fatty Acids
inferred← citeshttps://doi.org/10.3390/ijms26031109openalex-snapshot
The Molecular Mechanism of Clock in Thermal Adaptation of Two Congeneric Oyster Species
inferred← citeshttps://doi.org/10.3390/ijms26104523openalex-snapshot
LncRNA-Mediated Tissue-Specific Plastic Responses to Salinity Changes in Oysters
inferred← citeshttps://doi.org/10.6084/m9.figshare.26551057openalex-snapshot
Additional file 1 of A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
inferred← citeshttps://doi.org/10.6084/m9.figshare.26551060openalex-snapshot
Additional file 2 of A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
inferred← citeshttps://doi.org/10.6084/m9.figshare.26551120openalex-snapshot
Additional file 3 of A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
inferred← citeshttps://doi.org/10.6084/m9.figshare.26551126openalex-snapshot
Additional file 4 of A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
inferred← citeshttps://doi.org/10.6084/m9.figshare.26551129openalex-snapshot
Additional file 5 of A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
inferred← citeshttps://doi.org/10.6084/m9.figshare.26551132openalex-snapshot
Additional file 6 of A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
inferred← citeshttps://doi.org/10.6084/m9.figshare.26551135openalex-snapshot
Additional file 7 of A comparative analysis of mitochondrial ORFs provides new insights on expansion of mitochondrial genome size in Arcidae
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