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Locked nucleic acid building blocks as versatile tools for advanced G-quadruplex design

https://doi.org/10.1093/nar/gkaa720
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.200806244openalex-snapshot
Solution Structure of a Locked Nucleic Acid Modified Quadruplex: Introducing the V4 Folding Topology
inferredcites →https://doi.org/10.1002/anie.201404652openalex-snapshot
DNA Switches: From Principles to Applications
inferredcites →https://doi.org/10.1002/anie.201411887openalex-snapshot
Flipping a G‐Tetrad in a Unimolecular Quadruplex Without Affecting Its Global Fold
inferredcites →https://doi.org/10.1002/anie.201507569openalex-snapshot
Reversible pH Switch of Two‐Quartet G‐Quadruplexes Formed by Human Telomere
inferredcites →https://doi.org/10.1002/anie.201608275openalex-snapshot
Sugar–Edge Interactions in a DNA–RNA G‐Quadruplex: Evidence of Sequential C−H⋅⋅⋅O Hydrogen Bonds Contributing to RNA Quadruplex Folding
inferredcites →https://doi.org/10.1002/anie.201809328openalex-snapshot
Adenine‐Driven Structural Switch from a Two‐ to Three‐Quartet DNA G‐Quadruplex
inferredcites →https://doi.org/10.1002/anie.201907740openalex-snapshot
An Unprecedented Knot‐like G‐Quadruplex Peripheral Motif
inferredcites →https://doi.org/10.1002/bip.20591openalex-snapshot
Energetic aspects of locked nucleic acids quadruplex association and dissociation
inferredcites →https://doi.org/10.1002/cbic.201200481openalex-snapshot
Structural Investigations on the Anti‐HIV G‐Quadruplex‐Forming Oligonucleotide TGGGAG and Its Analogues: Evidence for the Presence of an A‐Tetrad
inferredcites →https://doi.org/10.1002/cbic.201800099openalex-snapshot
Fluorine‐Mediated Editing of a G‐Quadruplex Folding Pathway
inferredcites →https://doi.org/10.1002/cbic.201800642openalex-snapshot
Manipulating DNA G‐Quadruplex Structures by Using Guanosine Analogues
inferredcites →https://doi.org/10.1002/chem.200701255openalex-snapshot
Geometric Formalism for DNA Quadruplex Folding
inferredcites →https://doi.org/10.1002/chem.201001961openalex-snapshot
Selection of G‐Quadruplex Folding Topology with LNA‐Modified Human Telomeric Sequences in K+ Solution
inferredcites →https://doi.org/10.1002/chem.201803367openalex-snapshot
DNA–RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies
inferredcites →https://doi.org/10.1002/chem.201904044openalex-snapshot
Sugar Puckering Drives G‐Quadruplex Refolding: Implications for V‐Shaped Loops
inferredcites →https://doi.org/10.1002/cphc.201700260openalex-snapshot
The Role of the DNA Backbone in Minor‐Groove Ligand Binding
inferredcites →https://doi.org/10.1002/cplu.201600036openalex-snapshot
Utilization of G‐Quadruplex‐Forming Aptamers for the Construction of Luminescence Sensing Platforms
inferredcites →https://doi.org/10.1002/prot.20449openalex-snapshot
The CCPN data model for NMR spectroscopy: Development of a software pipeline
inferredcites →https://doi.org/10.1006/jmbi.2001.4916openalex-snapshot
V-shaped scaffold: a new architectural motif identified in an A·(G·G·G·G) pentad-containing dimeric DNA quadruplex involving stacked G(anti)·G(anti)·G(anti)·G(syn) tetrads11Edited by M. F. Summers
inferredcites →https://doi.org/10.1007/s002140050415openalex-snapshot
C-H...O and C-H...N interactions in RNA structures
inferredcites →https://doi.org/10.1016/j.biochi.2010.10.011openalex-snapshot
Effects of 8-methylguanine on structure, stability and kinetics of formation of tetramolecular quadruplexes
inferredcites →https://doi.org/10.1016/j.bios.2019.111475openalex-snapshot
Functionalized aptamer with an antiparallel G-quadruplex: Structural remodeling, recognition mechanism, and diagnostic applications targeting CTGF
inferredcites →https://doi.org/10.1016/j.bmc.2019.05.010openalex-snapshot
A structure-activity relationship of a thrombin-binding aptamer containing LNA in novel sites
inferredcites →https://doi.org/10.1016/j.cplett.2007.09.008openalex-snapshot
The whole of intramolecular H-bonding in the isolated DNA nucleoside thymidine. AIM electron density topological study
inferredcites →https://doi.org/10.1016/j.jmr.2010.07.007openalex-snapshot
The impact of pulse duration on composite WATERGATE pulse
inferredcites →https://doi.org/10.1016/j.str.2009.10.015openalex-snapshot
Solution Structure of a Unique G-Quadruplex Scaffold Adopted by a Guanosine-Rich Human Intronic Sequence
inferredcites →https://doi.org/10.1016/s1090-7807(02)00014-9openalex-snapshot
The Xplor-NIH NMR molecular structure determination package
inferredcites →https://doi.org/10.1021/acs.biochem.6b00925openalex-snapshot
Observation of a Dynamic G-Tetrad Flip in Intramolecular G-Quadruplexes
inferredcites →https://doi.org/10.1021/acs.jctc.5b00716openalex-snapshot
Refinement of the Sugar–Phosphate Backbone Torsion Beta for AMBER Force Fields Improves the Description of Z- and B-DNA
inferredcites →https://doi.org/10.1021/acs.jpclett.7b02428openalex-snapshot
Nonconventional C–H···F Hydrogen Bonds Support a Tetrad Flip in Modified G-Quadruplexes
inferredcites →https://doi.org/10.1021/acschembio.6b01096openalex-snapshot
Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes
inferredcites →https://doi.org/10.1021/acsomega.7b01649openalex-snapshot
Stability of the Na+ Form of the Human Telomeric G-Quadruplex: Role of Adenines in Stabilizing G-Quadruplex Structure
inferredcites →https://doi.org/10.1021/ct200162xopenalex-snapshot
Refinement of the Cornell et al. Nucleic Acids Force Field Based on Reference Quantum Chemical Calculations of Glycosidic Torsion Profiles
inferredcites →https://doi.org/10.1021/ct300275sopenalex-snapshot
Reference Simulations of Noncanonical Nucleic Acids with Different χ Variants of the AMBER Force Field: Quadruplex DNA, Quadruplex RNA, and Z-DNA
inferredcites →https://doi.org/10.1021/ja00124a002openalex-snapshot
A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules
inferredcites →https://doi.org/10.1021/ja012288dopenalex-snapshot
Locked Nucleic Acid (LNA) Recognition of RNA: NMR Solution Structures of LNA:RNA Hybrids
inferredcites →https://doi.org/10.1021/ja0348694openalex-snapshot
Small Change in a G-Rich Sequence, a Dramatic Change in Topology: New Dimeric G-Quadruplex Folding Motif with Unique Loop Orientations
inferredcites →https://doi.org/10.1021/ja039192zopenalex-snapshot
A Conformationally Constrained Nucleotide Analogue Controls the Folding Topology of a DNA G-Quadruplex
inferredcites →https://doi.org/10.1021/ja4125274openalex-snapshot
Structure and Conformational Dynamics of a Stacked Dimeric G-Quadruplex Formed by the Human CEB1 Minisatellite
inferredcites →https://doi.org/10.1021/jacs.8b05332openalex-snapshot
Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop
inferredcites →https://doi.org/10.1021/jp408909topenalex-snapshot
Optimization of an AMBER Force Field for the Artificial Nucleic Acid, LNA, and Benchmarking with NMR of L(CAAU)
inferredcites →https://doi.org/10.1038/nsb0298-104openalex-snapshot
Structural basis for G•C recognition in the DNA minor groove
inferredcites →https://doi.org/10.1038/s41570-017-0041openalex-snapshot
Quadruplex nucleic acids as targets for anticancer therapeutics
inferredcites →https://doi.org/10.1039/a708608copenalex-snapshot
LNA (locked nucleic acids): synthesis and high-affinity nucleic acid recognition
inferredcites →https://doi.org/10.1039/d0cc01285hopenalex-snapshot
Switching the type of V-loop in sugar-modified G-quadruplexes through altered fluorine interactions
inferredcites →https://doi.org/10.1073/pnas.92.1.180openalex-snapshot
Stereoelectronic effects of deoxyribose O4' on DNA conformation.
inferredcites →https://doi.org/10.1073/pnas.93.22.12116openalex-snapshot
Inter-strand C-H...O hydrogen bonds stabilizing four-stranded intercalated molecules: stereoelectronic effects of O4' in cytosine-rich DNA.
inferredcites →https://doi.org/10.1074/jbc.ra118.002666openalex-snapshot
A putative G-quadruplex structure in the proximal promoter of VEGFR-2 has implications for drug design to inhibit tumor angiogenesis
inferredcites →https://doi.org/10.1080/07391102.2011.10507374openalex-snapshot
Intramolecular CH…O Hydrogen Bonds in the AI and BI DNA-like Conformers of Canonical Nucleosides and their Watson-Crick Pairs. Quantum Chemical and AIM Analysis
inferredcites →https://doi.org/10.1080/07391102.2015.1033015openalex-snapshot
Molecular docking and dynamics simulations on the interaction of cationic porphyrin–anthraquinone hybrids with DNA G-quadruplexes
inferredcites →https://doi.org/10.1093/nar/gkaa008openalex-snapshot
Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs
inferredcites →https://doi.org/10.1093/nar/gkg680openalex-snapshot
3DNA: a software package for the analysis, rebuilding and visualization of three-dimensional nucleic acid structures
inferredcites →https://doi.org/10.1093/nar/gkh629openalex-snapshot
NMR solution structure of a parallel LNA quadruplex
inferredcites →https://doi.org/10.1093/nar/gkl144openalex-snapshot
NMR solution structures of LNA (locked nucleic acid) modified quadruplexes
inferredcites →https://doi.org/10.1093/nar/gkl655openalex-snapshot
Quadruplex DNA: sequence, topology and structure
inferredcites →https://doi.org/10.1093/nar/gkq1133openalex-snapshot
Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acids
inferredcites →https://doi.org/10.1093/nar/gkr288openalex-snapshot
R.E.D. Server: a web service for deriving RESP and ESP charges and building force field libraries for new molecules and molecular fragments
inferredcites →https://doi.org/10.1093/nar/gkr670openalex-snapshot
The insertion of two 8-methyl-2′-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands
inferredcites →https://doi.org/10.1093/nar/gks329openalex-snapshot
Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops
inferredcites →https://doi.org/10.1093/nar/gkt1312openalex-snapshot
Sugar-modified G-quadruplexes: effects of LNA-, 2′F-RNA– and 2′F-ANA-guanosine chemistries on G-quadruplex structure and stability
inferredcites →https://doi.org/10.1093/nar/gkt697openalex-snapshot
G-rich VEGF aptamer with locked and unlocked nucleic acid modifications exhibits a unique G-quadruplex fold
inferredcites →https://doi.org/10.1093/nar/gkv862openalex-snapshot
G-quadruplexes and their regulatory roles in biology
inferredcites →https://doi.org/10.1093/nar/gky1167openalex-snapshot
NMR solution structure of an asymmetric intermolecular leaped V-shape G-quadruplex: selective recognition of the d(G2NG3NG4) sequence motif by a short linear G-rich DNA probe
inferredcites →https://doi.org/10.1093/nar/gky886openalex-snapshot
NMR structure of a G-quadruplex formed by four d(G4C2) repeats: insights into structural polymorphism
inferredcites →https://doi.org/10.1111/j.1742-4658.2009.07464.xopenalex-snapshot
Human telomeric G‐quadruplex: structures of DNA and RNA sequences
inferredcites →https://doi.org/10.3389/fchem.2016.00038openalex-snapshot
Metal Cations in G-Quadruplex Folding and Stability
inferredcites →https://doi.org/10.3390/molecules24071294openalex-snapshot
Towards Understanding of Polymorphism of the G-rich Region of Human Papillomavirus Type 52

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Control of A/D Type Cpg-Dna Aggregates to a Suitable Size to Induce Strong Th-1 Immune Responses
inferred← citeshttps://doi.org/10.1002/bio.4141openalex-snapshot
An aptasensor for the detection of Pb2+ based on photoinduced electron transfer between a G‐quadruplex–hemin complex and a fluorophore
inferred← citeshttps://doi.org/10.1002/slct.202304286openalex-snapshot
Structural Aspects of Split G‐Quadruplexes in Quadruplex‐Duplex Hybrid Systems
inferred← citeshttps://doi.org/10.1016/j.bbrep.2023.101573openalex-snapshot
Control of A/D type CpG-ODN aggregates to a suitable size for induction of strong immunostimulant activity
inferred← citeshttps://doi.org/10.1016/j.biotechadv.2021.107902openalex-snapshot
Strategies to manipulate the performance of aptamers in SELEX, post-SELEX and microenvironment
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.139844openalex-snapshot
Na+-concentration dependent conformational switch of oncogene RET G-quadruplex DNA in solution
inferred← citeshttps://doi.org/10.1016/j.xcrp.2024.101858openalex-snapshot
Stable G quadruplex formed in promoter region of oncogene RET in physiological solution conditions
inferred← citeshttps://doi.org/10.1021/acs.biochem.1c00043openalex-snapshot
First Tandem Repeat of a Potassium Channel KCNN4 Minisatellite Folds into a V-Loop G-Quadruplex Structure
inferred← citeshttps://doi.org/10.1021/acs.jpclett.0c02969openalex-snapshot
Characterization of DNA G-quadruplex Topologies with NMR Chemical Shifts
inferred← citeshttps://doi.org/10.1021/jacs.3c08336openalex-snapshot
Showcasing Different G‑Quadruplex Folds of a G‑Rich Sequence: Between Rule-Based Prediction and Butterfly Effect
inferred← citeshttps://doi.org/10.1039/d0cb00211aopenalex-snapshot
Structural motifs and intramolecular interactions in non-canonical G-quadruplexes
inferred← citeshttps://doi.org/10.1039/d0cc08146aopenalex-snapshot
A novel minimal motif for left-handed G-quadruplex formation
inferred← citeshttps://doi.org/10.1039/d0cs01430copenalex-snapshot
Recent progress in non-native nucleic acid modifications
inferred← citeshttps://doi.org/10.1093/nar/gkaa1259openalex-snapshot
Bulges in left-handed G-quadruplexes
inferred← citeshttps://doi.org/10.1093/nar/gkae182openalex-snapshot
Comprehensive analysis of intramolecular G-quadruplex structures: furthering the understanding of their formalism
inferred← citeshttps://doi.org/10.1186/s12967-025-06473-8openalex-snapshot
The G-quadruplex ligand CX-5461: an innovative candidate for disease treatment
inferred← citeshttps://doi.org/10.31635/ccschem.021.202101357openalex-snapshot
Exploring Sequence Space to Design Controllable G-Quadruplex Topology Switches
inferred← citeshttps://doi.org/10.3390/molecules27134165openalex-snapshot
Discriminating between Parallel, Anti-Parallel and Hybrid G-Quadruplexes: Mechanistic Details on Their Binding to Small Molecules
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