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Tyrosine kinase c-Abl couples RNA polymerase II transcription to DNA double-strand breaks
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1 of the 84 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1038/nature12201 (notice 2019-04-11).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1038/387516a0openalex-snapshotAtaxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation
inferredcites →https://doi.org/10.1038/ncb3643openalex-snapshotDamage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks
inferredcites →https://doi.org/10.1038/ncomms13049openalex-snapshotClassical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes
inferredcites →https://doi.org/10.1038/ncomms15656openalex-snapshotA damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks
inferredcites →https://doi.org/10.1038/nrg3355openalex-snapshotRNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond
inferredcites →https://doi.org/10.1093/nar/gkx403openalex-snapshotStrong transcription blockage mediated by R-loop formation within a G-rich homopurine–homopyrimidine sequence localized in the vicinity of the promoter
inferredcites →https://doi.org/10.1093/nar/gky1107openalex-snapshotNext-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks
inferredcites →https://doi.org/10.1242/jcs.182188openalex-snapshotDICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors
inferredcites →https://doi.org/10.7554/elife.02105openalex-snapshotTyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4781335openalex-extractedThe Abl1 Tyrosine Kinase and p53 are Key Players in Doxorubicin-Induced Cardiomyopathy and Their Cell Death Signaling Differs in Atrial and Ventricular Cardiomyocytes
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117699openalex-snapshotABL kinase inactivation induces transcription-replication conflicts and impairs replication fork progression in metastatic small cell lung cancer
inferred← citeshttps://doi.org/10.1016/j.tiv.2022.105323openalex-snapshotDeficiency of TRDMT1 impairs exogenous RNA-based response and promotes retrotransposon activity during long-term culture of osteosarcoma cells
inferred← citeshttps://doi.org/10.1101/2023.10.20.563274openalex-snapshotRNA Polymerase II-mediated transcription is required for repair of ribosomal DNA breaks in nucleolar caps, guarding against genomic instability
inferred← citeshttps://doi.org/10.1101/2025.01.22.634233openalex-snapshotDistinct Mechanisms of Recognition of Phosphorylated RNAPII C-Terminal Domain by BRCT Repeats of the BRCA1–BARD1 Complex: Insights from Structural and Functional Analyses
inferred← citeshttps://doi.org/10.1101/gr.278644.123openalex-snapshotTyrosine 1–phosphorylated RNA polymerase II transcribes PROMPTs to facilitate proximal promoter pausing and induce global transcriptional repression in response to DNA damage
inferred← citeshttps://doi.org/10.1126/sciadv.abi6896openalex-snapshotGene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity
inferred← citeshttps://doi.org/10.1186/s12967-024-05623-8openalex-snapshotThe Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes
inferred← citeshttps://doi.org/10.3389/fgene.2021.779554openalex-snapshotA Mutation-Related Long Noncoding RNA Signature of Genome Instability Predicts Immune Infiltration and Hepatocellular Carcinoma Prognosis
inferred← citeshttps://doi.org/10.62347/aiid7730openalex-snapshotStudy on serum tRF-30-RRJ89O9NF5W8 as a potential biomarker for clinical diagnosis of gastric cancer
inferred← citeshttps://doi.org/10.64898/2026.01.30.702603openalex-snapshotThe glycine-arginine-rich motif of 53BP1 modulates RNA interactions necessary for its liquid-liquid phase separation during DNA Damage Response
inferred← citeshttps://doi.org/10.7554/elife.48725openalex-snapshotTyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
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