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Inhibition of Thyroid Hormone Release from Cultured Amphibian Thyroid Glands by Methimazole, 6-Propylthiouracil, and Perchlorate

https://doi.org/10.1093/toxsci/kfq166
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1097-010x(20000501)286:6<625::aid-jez9>3.0.co;2-qopenalex-snapshot
Direct influence of melatonin on the thyroid and comparison with prolactin
inferredcites →https://doi.org/10.1002/etc.5620210227openalex-snapshot
Environmentally relevant concentrations of ammonium perchlorate inhibit development and metamorphosis in Xenopus laevis
inferredcites →https://doi.org/10.1002/jez.1402460309openalex-snapshot
Thyroid status influences in vitro thyrotropin and growth hormone responses to thyrotropin‐releasing hormone by pituitary glands of hatchling slider turtles (Pseudemys scripta elegans)
inferredcites →https://doi.org/10.1006/gcen.1993.1102openalex-snapshot
Acceleration of Anuran Amphibian Metamorphosis by Corticotropin-Releasing Hormone-like Peptides
inferredcites →https://doi.org/10.1006/taap.2000.9019openalex-snapshot
Dietary Genistein Inactivates Rat Thyroid Peroxidase in Vivo without an Apparent Hypothyroid Effect
inferredcites →https://doi.org/10.1007/pl00000941openalex-snapshot
Human Genome and Diseases: Review¶The TSH receptor and its role in thyroid disease
inferredcites →https://doi.org/10.1016/0003-2697(85)90442-7openalex-snapshot
Measurement of protein using bicinchoninic acid
inferredcites →https://doi.org/10.1016/0006-2952(82)90296-9openalex-snapshot
Mechanism of inactivation of thyroid peroxidase by thioureylene drugs
inferredcites →https://doi.org/10.1016/0016-6480(68)90006-3openalex-snapshot
Ultrastructural observations on the thyroid gland of Xenopus laevis daudin throughout metamorphosis
inferredcites →https://doi.org/10.1016/0303-7207(91)90216-fopenalex-snapshot
ATP, bradykinin, TRH and TSH activate the Ca2+-phosphatidylinositol cascade of human thyrocytes in primary culture
inferredcites →https://doi.org/10.1016/b978-0-12-455403-0.50015-3openalex-snapshot
THE BIOLOGY OF METAMORPHOSIS
inferredcites →https://doi.org/10.1016/j.aquatox.2010.01.014openalex-snapshot
Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis
inferredcites →https://doi.org/10.1016/j.taap.2009.12.004openalex-snapshot
Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L
inferredcites →https://doi.org/10.1016/s0021-9258(17)36705-4openalex-snapshot
The human thyrotropin receptor activates G-proteins Gs and Gq/11.
inferredcites →https://doi.org/10.1016/s0031-6997(24)01350-4openalex-snapshot
Perchlorate and the Thyroid Gland
inferredcites →https://doi.org/10.1016/s0300-483x(02)00469-9openalex-snapshot
Xenoendocrine disrupters-tiered screening and testing
inferredcites →https://doi.org/10.1023/a:1008992932155openalex-snapshot
OECD Activity on Endocrine Disrupters Test Guidelines Development
inferredcites →https://doi.org/10.1080/10408440601123446openalex-snapshot
General Background on the Hypothalamic-Pituitary-Thyroid (HPT) Axis
inferredcites →https://doi.org/10.1089/thy.1998.8.827openalex-snapshot
Effects of Environmental Synthetic Chemicals on Thyroid Function
inferredcites →https://doi.org/10.1093/toxsci/kfi246openalex-snapshot
Progress towards Development of an Amphibian-Based Thyroid Screening Assay Using Xenopus laevis. Organismal and Thyroidal Responses to the Model Compounds 6-Propylthiouracil, Methimazole, and Thyroxine
inferredcites →https://doi.org/10.1152/physrev.1992.72.3.667openalex-snapshot
Physiological and pathological regulation of thyroid cell proliferation and differentiation by thyrotropin and other factors
inferredcites →https://doi.org/10.1210/edrv.22.5.0444openalex-snapshot
Regulation of Thyroid Cell Proliferation by TSH and Other Factors: A Critical Evaluation of in Vitro Models
inferredcites →https://doi.org/10.1210/en.2006-1280openalex-snapshot
The Ultraviolet Filter Benzophenone 2 Interferes with the Thyroid Hormone Axis in Rats and Is a Potent in Vitro Inhibitor of Human Recombinant Thyroid Peroxidase
inferredcites →https://doi.org/10.1210/endo-74-6-973openalex-snapshot
Thyroidal Iodine Heterogeneity: “Last Come, First Served” System of Iodine Turnover
inferredcites →https://doi.org/10.1210/jcem-43-1-152openalex-snapshot
Effect of Antithyroid Agents 6-Propyl-2-Thiouracil and l-Methyl-2-Mercaptoimidazole on Human Thyroid Iodide Peroxidase
inferredcites →https://doi.org/10.1289/ehp.9369openalex-snapshot
Endocrine Disruptors and the Thyroid Gland—A Combined in Vitro and in Vivo Analysis of Potential New Biomarkers
inferredcites →https://doi.org/10.1289/ehp.99107407openalex-snapshot
Screening Methods for Thyroid Hormone Disruptors
inferredcites →https://doi.org/10.1530/eje.1.02128openalex-snapshot
Environmental chemicals and thyroid function
inferredcites →https://doi.org/10.1787/a17a1437-enopenalex-snapshot
Detailed Review Paper on Thyroid Hormone Disruption Assays
inferredcites →https://doi.org/10.1897/04-105r.1openalex-snapshot
Metamorphic inhibition of Xenopus laevis by sodium perchlorate: Effects on development and thyroid histology
inferredcites →https://doi.org/10.1897/1551-5028(2002)021<0424:ercoap>2.0.co;2openalex-snapshot
ENVIRONMENTALLY RELEVANT CONCENTRATIONS OF AMMONIUM PERCHLORATE INHIBIT DEVELOPMENT AND METAMORPHOSIS IN XENOPUS LAEVIS
inferredcites →https://doi.org/10.2307/1439568openalex-snapshot
Normal Table of Xenopus Laevis (Daudin)
inferredcites →https://doi.org/10.5281/zenodo.16253179openalex-snapshot
Thyrotropic Activity of Various Adenohypophyseal Hormones of the Bullfrog(Endocrinology)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.12688/openreseurope.18739.1zenodo-depositor-declared
A 2024 inventory of test methods relevant to thyroid hormone system disruption for human health and environmental regulatory hazard assessment
inferred← citeshttps://doi.org/10.1002/tox.22509openalex-snapshot
Evaluation of hypothalamus‐pituitary‐thyroid axis function by chronic perchlorate exposure in male rats
inferred← citeshttps://doi.org/10.1007/s10646-018-1911-yopenalex-snapshot
Validity of fish, birds and mammals as surrogates for amphibians and reptiles in pesticide toxicity assessment
inferred← citeshttps://doi.org/10.1007/s12519-013-0398-0openalex-snapshot
The differences in T and B cell subsets in thyroid of children with Graves’ disease and Hashimoto’s thyroiditis
inferred← citeshttps://doi.org/10.1007/s40974-017-0055-xopenalex-snapshot
Perchlorate in drinking water around rocket manufacturing and testing facilities and firework manufacturing sites in Kerala, India
inferred← citeshttps://doi.org/10.1016/b978-0-443-16020-2.00003-6openalex-snapshot
Environmental influences on hormones and reproduction in amphibians
inferred← citeshttps://doi.org/10.1016/j.aquatox.2016.05.011openalex-snapshot
The synthetic gestagen levonorgestrel directly affects gene expression in thyroid and pituitary glands of Xenopus laevis tadpoles
inferred← citeshttps://doi.org/10.1016/j.aquatox.2018.04.009openalex-snapshot
An AOP-based alternative testing strategy to predict the impact of thyroid hormone disruption on swim bladder inflation in zebrafish
inferred← citeshttps://doi.org/10.1016/j.crtox.2021.01.001openalex-snapshot
In vitro assays for characterization of distinct multiple catalytic activities of thyroid peroxidase using LC-MS/MS
inferred← citeshttps://doi.org/10.1016/j.tiv.2013.02.012openalex-snapshot
Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals
inferred← citeshttps://doi.org/10.1016/j.tox.2013.08.006openalex-snapshot
Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat
inferred← citeshttps://doi.org/10.1016/j.toxrep.2026.102234openalex-snapshot
Optimization of an ex vivo model to test the ability of chemicals to disrupt thyroid hormone synthesis
inferred← citeshttps://doi.org/10.1016/j.vascn.2017.04.015openalex-snapshot
A simple short term method to study thyroid disruption using a fetal rat thyroid culture
inferred← citeshttps://doi.org/10.1016/j.ygcen.2014.10.018openalex-snapshot
Changes in gastric sodium–iodide symporter (NIS) activity are associated with differences in thyroid gland sensitivity to perchlorate during metamorphosis
inferred← citeshttps://doi.org/10.1021/tx400310wopenalex-snapshot
Development of a Thyroperoxidase Inhibition Assay for High-Throughput Screening
inferred← citeshttps://doi.org/10.1073/pnas.1803794116openalex-snapshot
Stage-dependent cardiac regeneration in Xenopus is regulated by thyroid hormone availability
inferred← citeshttps://doi.org/10.1080/15275922.2015.1022914openalex-snapshot
Review on Fate, Toxicity, and Remediation of Perchlorate
inferred← citeshttps://doi.org/10.1093/toxsci/kfad063openalex-snapshot
Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption
inferred← citeshttps://doi.org/10.1093/toxsci/kfae014openalex-snapshot
Technical evaluation and standardization of the human thyroid microtissue assay
inferred← citeshttps://doi.org/10.1093/toxsci/kfq231openalex-snapshot
The Use of Cultured Amphibian Thyroid Glands to Detect Thyroid Hormone Disruptors
inferred← citeshttps://doi.org/10.1093/toxsci/kfv090openalex-snapshot
In Vitro,Ex Vivo, andIn VivoDetermination of Thyroid Hormone Modulating Activity of Benzothiazoles
inferred← citeshttps://doi.org/10.1093/toxsci/kfw034openalex-snapshot
Tiered High-Throughput Screening Approach to Identify Thyroperoxidase Inhibitors Within the ToxCast Phase I and II Chemical Libraries
inferred← citeshttps://doi.org/10.1093/toxsci/kfz238openalex-snapshot
Development of anIn VitroHuman Thyroid Microtissue Model for Chemical Screening
inferred← citeshttps://doi.org/10.1210/er.2011-1050openalex-snapshot
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
inferred← citeshttps://doi.org/10.1242/dev.175893openalex-snapshot
Adaptive correction of craniofacial defects in pre-metamorphic Xenopus laevis tadpoles involves thyroid hormone-independent tissue remodeling
inferred← citeshttps://doi.org/10.1787/447c5cba-enopenalex-snapshot
Thyroperoxidase inhibition leading to increased mortality via reduced anterior swim bladder inflation
inferred← citeshttps://doi.org/10.1787/7ca86a34-enopenalex-snapshot
Adverse Outcome Pathway on inhibition of Na+/I- symporter (NIS) leads to learning and memory impairment
inferred← citeshttps://doi.org/10.1787/9789264221352-enopenalex-snapshot
Detailed Review Paper on the State of the Science on Novel In Vitro and In Vivo Screening and Testing Methods and Endpoints for Evaluating Endocrine Disruptors
inferred← citeshttps://doi.org/10.1787/9789264274716-enopenalex-snapshot
New Scoping Document on in vitro and ex vivo Assays for the Identification of Modulators of Thyroid Hormone Signalling
inferred← citeshttps://doi.org/10.1787/ea5aa069-enopenalex-snapshot
Adverse Outcome Pathway on inhibition of Thyroperoxidase and subsequent adverse neurodevelopmental outcomes in mammals
inferred← citeshttps://doi.org/10.2174/2213988501408010036openalex-snapshot
Identification of Thyroid Hormone Receptor Active Compounds Using a Quantitative High-Throughput Screening Platform
inferred← citeshttps://doi.org/10.23880/aabsc-16000167openalex-snapshot
Hashimoto’s Thyroiditis Autoimmune Disease: Background and Current Status, Update Overview of Biotechnological and Biomedical Fields and Future Trends for 3D Models
inferred← citeshttps://doi.org/10.3109/10408444.2012.737762openalex-snapshot
Alternatives to in vivo tests to detect endocrine disrupting chemicals (EDCs) in fish and amphibians – screening for estrogen, androgen and thyroid hormone disruption
inferred← citeshttps://doi.org/10.3389/fendo.2019.00276openalex-snapshot
Contaminant and Environmental Influences on Thyroid Hormone Action in Amphibian Metamorphosis
inferred← citeshttps://doi.org/10.70675/d8644141z8164z46abzb0efzb1256b0780f4openalex-snapshot
Développement d'un test pour l'identification de molécules actives sur l'axe thyroïdien basé sur une lignée transgénique de poisson médaka (Oryzias latipes)
inferred← citeshttps://doi.org/10.70675/f8d646ffzf184z40e1z848az174a3d652f5dopenalex-snapshot
Gènes cibles des hormones thyroïdiennes, un regard nouveau par le prisme des analyses pangénomiques
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