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Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption

https://doi.org/10.1093/toxsci/kfad063
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inferredcites →https://doi.org/10.1002/alr.21565openalex-snapshot
Evaluation of olfactory function in adults with primary hypothyroidism
inferredcites →https://doi.org/10.1002/dvdy.22392openalex-snapshot
Thyroid hormone accelerates opsin expression during early photoreceptor differentiation and induces opsin switching in differentiated TRα‐expressing cones of the salmonid retina
inferredcites →https://doi.org/10.1002/dvdy.76openalex-snapshot
Thyroid hormone coordinates developmental trajectories but does not underlie developmental truncation in danionins
inferredcites →https://doi.org/10.1002/etc.34openalex-snapshot
Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
inferredcites →https://doi.org/10.1002/etc.3805openalex-snapshot
Advancing the adverse outcome pathway framework—An international horizon scanning approach
inferredcites →https://doi.org/10.1002/etc.3855openalex-snapshot
Impaired swim bladder inflation in early life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid
inferredcites →https://doi.org/10.1002/etc.4124openalex-snapshot
Adverse outcome pathway networks II: Network analytics
inferredcites →https://doi.org/10.1002/etc.4125openalex-snapshot
Adverse outcome pathway networks I: Development and applications
inferredcites →https://doi.org/10.1002/etc.4682openalex-snapshot
Critical Review of Read-Across Potential in Testing for Endocrine-Related Effects in Vertebrate Ecological Receptors
inferredcites →https://doi.org/10.1002/etc.5452openalex-snapshot
AOP Report: Thyroperoxidase Inhibition Leading to Altered Visual Function in Fish Via Altered Retinal Layer Structure
inferredcites →https://doi.org/10.1002/etc.5501openalex-snapshot
Defining the Biologically Plausible Taxonomic Domain of Applicability of an Adverse Outcome Pathway: A Case Study Linking Nicotinic Acetylcholine Receptor Activation to Colony Death
inferredcites →https://doi.org/10.1002/etc.5620210318openalex-snapshot
Environmentally relevant concentrations of ammonium perchlorate inhibit thyroid function and alter sex ratios in developing Xenopus laevis
inferredcites →https://doi.org/10.1002/jat.2825openalex-snapshot
Establishment of transactivation assay systems using fish, amphibian, reptilian and human thyroid hormone receptors
inferredcites →https://doi.org/10.1002/mnfr.200900489openalex-snapshot
Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism
inferredcites →https://doi.org/10.1006/gcen.1998.7197openalex-snapshot
Characterization of Thyroid Hormone 5′-Monodeiodinase Activity in the Turtle (Trachemys scripta)
inferredcites →https://doi.org/10.1006/gcen.1999.7326openalex-snapshot
Deiodination and Deconjugation of Thyroid Hormone Conjugates and Type I Deiodination in Liver of Rainbow Trout, Oncorhynchus mykiss
inferredcites →https://doi.org/10.1006/gcen.1999.7384openalex-snapshot
Hepatic Outer-Ring Deiodinase in a Mexican Endemic Lizard (Sceloporus grammicus)
inferredcites →https://doi.org/10.1006/gcen.2000.7528openalex-snapshot
Effect of Diethylstilbestrol on Thyroid Hormone Binding to Amphibian Transthyretins
inferredcites →https://doi.org/10.1007/s00204-020-02664-yopenalex-snapshot
Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay
inferredcites →https://doi.org/10.1007/s00204-020-02961-6openalex-snapshot
A review of species differences in the control of, and response to, chemical-induced thyroid hormone perturbations leading to thyroid cancer
inferredcites →https://doi.org/10.1007/s00204-021-03006-2openalex-snapshot
Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition
inferredcites →https://doi.org/10.1007/s10038-006-0391-8openalex-snapshot
Evolutionary dynamics of olfactory and other chemosensory receptor genes in vertebrates
inferredcites →https://doi.org/10.1016/0009-2797(90)90034-kopenalex-snapshot
Interaction of chlorinated phenols with thyroxine binding sites of human transthyretin, albumin and thyroid binding globulin
inferredcites →https://doi.org/10.1016/b978-0-12-374930-7.10014-7openalex-snapshot
Endocrine Disruption of Reproduction in Reptiles
inferredcites →https://doi.org/10.1016/j.aquatox.2010.01.014openalex-snapshot
Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis
inferredcites →https://doi.org/10.1016/j.aquatox.2012.10.013openalex-snapshot
Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole
inferredcites →https://doi.org/10.1016/j.aquatox.2014.12.011openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.aquatox.2015.12.015openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.aquatox.2015.12.023openalex-snapshot
Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part II: Zebrafish
inferredcites →https://doi.org/10.1016/j.aquatox.2015.12.024openalex-snapshot
Impaired anterior swim bladder inflation following exposure to the thyroid peroxidase inhibitor 2-mercaptobenzothiazole part I: Fathead minnow
inferredcites →https://doi.org/10.1016/j.aquatox.2016.03.006openalex-snapshot
Permethrin is a potential thyroid-disrupting chemical: In vivo and in silico envidence
inferredcites →https://doi.org/10.1016/j.aquatox.2017.06.019openalex-snapshot
A multi-tiered, in vivo, quantitative assay suite for environmental disruptors of thyroid hormone signaling
inferredcites →https://doi.org/10.1016/j.aquatox.2018.04.009openalex-snapshot
An AOP-based alternative testing strategy to predict the impact of thyroid hormone disruption on swim bladder inflation in zebrafish
inferredcites →https://doi.org/10.1016/j.aquatox.2020.105623openalex-snapshot
Amiodarone bioconcentration and suppression of metamorphosis in Xenopus
inferredcites →https://doi.org/10.1016/j.aquatox.2022.106227openalex-snapshot
Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase
inferredcites →https://doi.org/10.1016/j.bbagen.2012.07.015openalex-snapshot
Function of thyroid hormone transporters in the central nervous system
inferredcites →https://doi.org/10.1016/j.bcp.2011.08.027openalex-snapshot
Use of comprehensive screening methods to detect selective human CAR activators
inferredcites →https://doi.org/10.1016/j.bcp.2013.08.012openalex-snapshot
The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism
inferredcites →https://doi.org/10.1016/j.canlet.2019.09.017openalex-snapshot
Mouse models of thyroid cancer: Bridging pathogenesis and novel therapeutics
inferredcites →https://doi.org/10.1016/j.cbpa.2006.01.017openalex-snapshot
Thiourea-induced thyroid hormone depletion impairs testicular recrudescence in the air-breathing catfish, Clarias gariepinus
inferredcites →https://doi.org/10.1016/j.cbpc.2008.01.002openalex-snapshot
Interaction of diethylstilbestrol and ioxynil with transthyretin in chicken serum
inferredcites →https://doi.org/10.1016/j.chemosphere.2007.04.010openalex-snapshot
Disruption of thyroid hormone binding to sea bream recombinant transthyretin by ioxinyl and polybrominated diphenyl ethers
inferredcites →https://doi.org/10.1016/j.cub.2015.02.049openalex-snapshot
The reptilian brain
inferredcites →https://doi.org/10.1016/j.cvex.2007.10.002openalex-snapshot
The Reptilian Thyroid and Parathyroid Glands
inferredcites →https://doi.org/10.1016/j.envint.2020.105783openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.envint.2021.106458openalex-snapshot
Concentrations and endocrine disruptive potential of phthalates in marine mammals from the Norwegian Arctic
inferredcites →https://doi.org/10.1016/j.envpol.2018.02.038openalex-snapshot
Lifecycle exposure to perchlorate differentially alters morphology, biochemistry, and transcription as well as sperm motility in Silurana tropicalis frogs
inferredcites →https://doi.org/10.1016/j.envpol.2019.05.110openalex-snapshot
Early life exposure to triphenyl phosphate: Effects on thyroid function, growth, and resting metabolic rate of Japanese quail (Coturnix japonica) chicks
inferredcites →https://doi.org/10.1016/j.envpol.2019.113695openalex-snapshot
Assessment of the effects of early life exposure to triphenyl phosphate on fear, boldness, aggression, and activity in Japanese quail (Coturnix japonica) chicks
inferredcites →https://doi.org/10.1016/j.envpol.2021.117135openalex-snapshot
Testing for heterotopia formation in rats after developmental exposure to selected in vitro inhibitors of thyroperoxidase
inferredcites →https://doi.org/10.1016/j.envpol.2021.117654openalex-snapshot
The pyriproxyfen metabolite, 4′–OH–PPF, disrupts thyroid hormone signaling in neural stem cells, modifying neurodevelopmental genes affected by ZIKA virus infection.
inferredcites →https://doi.org/10.1016/j.envres.2021.111906openalex-snapshot
Disruption by stealth - Interference of endocrine disrupting chemicals on hormonal crosstalk with thyroid axis function in humans and other animals
inferredcites →https://doi.org/10.1016/j.etap.2015.01.016openalex-snapshot
Comparison of the in vitro effects of TCDD, PCB 126 and PCB 153 on thyroid-restricted gene expression and thyroid hormone secretion by the chicken thyroid gland
inferredcites →https://doi.org/10.1016/j.exer.2018.09.018openalex-snapshot
Knockdown of the thyroid hormone transporter MCT8 in chicken retinal precursor cells hampers early retinal development and results in a shift towards more UV/blue cones at the expense of green/red cones
inferredcites →https://doi.org/10.1016/j.heares.2010.05.004openalex-snapshot
Sensory regeneration in the vertebrate inner ear: Differences at the levels of cells and species
inferredcites →https://doi.org/10.1016/j.isci.2020.100899openalex-snapshot
A Pivotal Genetic Program Controlled by Thyroid Hormone during the Maturation of GABAergic Neurons
inferredcites →https://doi.org/10.1016/j.jri.2011.02.009openalex-snapshot
Thyroid hormone receptors and reproduction
inferredcites →https://doi.org/10.1016/j.lfs.2004.08.030openalex-snapshot
Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis
inferredcites →https://doi.org/10.1016/j.mce.2005.07.006openalex-snapshot
Environmental chemicals as thyroid hormone analogues: New studies indicate that thyroid hormone receptors are targets of industrial chemicals?
inferredcites →https://doi.org/10.1016/j.mce.2013.08.025openalex-snapshot
Autonomous functions of murine thyroid hormone receptor TRα and TRβ in cochlear hair cells
inferredcites →https://doi.org/10.1016/j.mce.2016.01.018openalex-snapshot
Deiodinase knockdown affects zebrafish eye development at the level of gene expression, morphology and function
inferredcites →https://doi.org/10.1016/j.mce.2016.01.020openalex-snapshot
Patterns of thyroid hormone receptor expression in zebrafish and generation of a novel model of resistance to thyroid hormone action
inferredcites →https://doi.org/10.1016/j.mce.2016.09.007openalex-snapshot
Implication of thyroid hormone signaling in neural crest cells migration: Evidence from thyroid hormone receptor beta knockdown and NH3 antagonist studies
inferredcites →https://doi.org/10.1016/j.mce.2017.01.038openalex-snapshot
Thyroid hormone biosynthesis and release
inferredcites →https://doi.org/10.1016/j.mce.2019.110635openalex-snapshot
Inhibition of the thyroid hormonogenic H2O2 production by Duox/DuoxA in zebrafish reveals VAS2870 as a new goitrogenic compound
inferredcites →https://doi.org/10.1016/j.neuro.2018.04.013openalex-snapshot
Moderate perinatal thyroid hormone insufficiency alters visual system function in adult rats
inferredcites →https://doi.org/10.1016/j.neuro.2019.05.008openalex-snapshot
Changes in thyroid hormone activity disrupt photomotor behavior of larval zebrafish
inferredcites →https://doi.org/10.1016/j.neuro.2021.03.003openalex-snapshot
Investigation of NH3 as a selective thyroid hormone receptor modulator in larval zebrafish (Danio rerio)
inferredcites →https://doi.org/10.1016/j.semcdb.2020.09.007openalex-snapshot
Thyroid hormone, gene expression, and Central Nervous System: Where we are
inferredcites →https://doi.org/10.1016/j.taap.2005.06.014openalex-snapshot
Analysis of thyroid hormone receptor βA mRNA expression in Xenopus laevis tadpoles as a means to detect agonism and antagonism of thyroid hormone action
inferredcites →https://doi.org/10.1016/j.taap.2006.01.009openalex-snapshot
A mode of action for induction of thyroid gland tumors by Pyrethrins in the rat
inferredcites →https://doi.org/10.1016/j.taap.2008.05.020openalex-snapshot
Developmental neurotoxicity of Propylthiouracil (PTU) in rats: Relationship between transient hypothyroxinemia during development and long-lasting behavioural and functional changes
inferredcites →https://doi.org/10.1016/j.taap.2012.01.029openalex-snapshot
Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways
inferredcites →https://doi.org/10.1016/j.taap.2018.02.006openalex-snapshot
AOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks
inferredcites →https://doi.org/10.1016/j.tiv.2016.01.014openalex-snapshot
Effect of triclosan, triclocarban, 2,2′,4,4′-tetrabromodiphenyl ether, and bisphenol A on the iodide uptake, thyroid peroxidase activity, and expression of genes involved in thyroid hormone synthesis
inferredcites →https://doi.org/10.1016/j.tiv.2016.12.006openalex-snapshot
Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS)
inferredcites →https://doi.org/10.1016/j.tiv.2017.02.023openalex-snapshot
Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals
inferredcites →https://doi.org/10.1016/j.tiv.2019.104662openalex-snapshot
A rapid assay of human thyroid peroxidase activity
inferredcites →https://doi.org/10.1016/j.tiv.2020.105073openalex-snapshot
In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase
inferredcites →https://doi.org/10.1016/j.tiv.2021.105141openalex-snapshot
Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals
inferredcites →https://doi.org/10.1016/j.tox.2004.11.037openalex-snapshot
Thyroid hormone-like and estrogenic activity of hydroxylated PCBs in cell culture
inferredcites →https://doi.org/10.1016/j.tox.2010.08.012openalex-snapshot
Structure-based investigation on the binding interaction of hydroxylated polybrominated diphenyl ethers with thyroxine transport proteins
inferredcites →https://doi.org/10.1016/j.tox.2013.08.006openalex-snapshot
Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat
inferredcites →https://doi.org/10.1016/j.tox.2013.08.017openalex-snapshot
Structure–activity relationships of 44 halogenated compounds for iodotyrosine deiodinase-inhibitory activity
inferredcites →https://doi.org/10.1016/j.tox.2016.08.011openalex-snapshot
Binding interactions of perfluoroalkyl substances with thyroid hormone transport proteins and potential toxicological implications
inferredcites →https://doi.org/10.1016/j.tox.2020.152562openalex-snapshot
Effects of butylparaben exposure on thyroid peroxidase (TPO) and type 1 iodothyronine deiodinase (D1) in female Wistar rats
inferredcites →https://doi.org/10.1016/j.toxlet.2021.10.010openalex-snapshot
Perinatal exposure to the thyroperoxidase inhibitors methimazole and amitrole perturbs thyroid hormone system signaling and alters motor activity in rat offspring
inferredcites →https://doi.org/10.1016/j.yfrne.2013.04.002openalex-snapshot
Thyroid hormone and seasonal regulation of reproduction
inferredcites →https://doi.org/10.1016/j.ygcen.2006.11.013openalex-snapshot
Effects of larval–juvenile treatment with perchlorate and co-treatment with thyroxine on zebrafish sex ratios
inferredcites →https://doi.org/10.1016/j.ygcen.2009.09.011openalex-snapshot
Combined antisense knockdown of type 1 and type 2 iodothyronine deiodinases disrupts embryonic development in zebrafish (Danio rerio)
inferredcites →https://doi.org/10.1016/j.ygcen.2010.04.013openalex-snapshot
Developmental regulation of gene expression in the thyroid gland of Xenopus laevis tadpoles
inferredcites →https://doi.org/10.1016/j.ygcen.2012.12.018openalex-snapshot
Regulation of gonadal sex ratios and pubertal development by the thyroid endocrine system in zebrafish (Danio rerio)
inferredcites →https://doi.org/10.1016/j.ygcen.2014.03.015openalex-snapshot
Mechanisms of crosstalk between endocrine systems: Regulation of sex steroid hormone synthesis and action by thyroid hormones
inferredcites →https://doi.org/10.1016/j.ygcen.2018.04.023openalex-snapshot
Thyroid hormone actions on male reproductive system of teleost fish
inferredcites →https://doi.org/10.1016/j.ygcen.2022.114033openalex-snapshot
Tpo knockout in zebrafish partially recapitulates clinical manifestations of congenital hypothyroidism and reveals the involvement of TH in proper development of glucose homeostasis
inferredcites →https://doi.org/10.1016/j.yhbeh.2005.02.001openalex-snapshot
Endocrine control of Anguilla anguilla glass eel dispersal: Effect of thyroid hormones on locomotor activity and rheotactic behavior
inferredcites →https://doi.org/10.1016/j.yhbeh.2017.09.016openalex-snapshot
Behavioral and molecular analyses of olfaction-mediated avoidance responses of Rana ( Lithobates ) catesbeiana tadpoles: Sensitivity to thyroid hormones, estrogen, and treated municipal wastewater effluent
inferredcites →https://doi.org/10.1016/j.yrtph.2018.07.025openalex-snapshot
Human relevance of follicular thyroid tumors in rodents caused by non-genotoxic substances
inferredcites →https://doi.org/10.1016/j.yrtph.2020.104736openalex-snapshot
Weight of Evidence and Human Relevance Evaluation of the Benfluralin Mode of Action in Rats (Part II): Thyroid carcinogenesis
inferredcites →https://doi.org/10.1016/s0016-6480(02)00570-1openalex-snapshot
The liver of Fundulus heteroclitus expresses deiodinase type 1 mRNA
inferredcites →https://doi.org/10.1016/s0016-6480(03)00197-7openalex-snapshot
The effect of endocrine disrupting chemicals on thyroid hormone binding to Japanese quail transthyretin and thyroid hormone receptor
inferredcites →https://doi.org/10.1016/s0041-008x(02)00045-5openalex-snapshot
Competitive interactions of chlorinated phenol compounds with 3,3′,5-triiodothyronine binding to transthyretin: detection of possible thyroid-disrupting chemicals in environmental waste water
inferredcites →https://doi.org/10.1016/s0044-8486(98)00347-0openalex-snapshot
Effect of thyroxine on the decrease of aggressive behaviour of four salmonids during the parr-smolt transformation
inferredcites →https://doi.org/10.1016/s0300-483x(02)00222-6openalex-snapshot
Polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs) and chlorinated paraffins (CPs) in rats—testing interactions and mechanisms for thyroid hormone effects
inferredcites →https://doi.org/10.1016/s0303-7207(02)00302-7openalex-snapshot
Endocrine disrupting chemicals: interference of thyroid hormone binding to transthyretins and to thyroid hormone receptors
inferredcites →https://doi.org/10.1016/s0892-0362(98)00065-8openalex-snapshot
Low-Frequency Hearing Loss Following Perinatal Exposure to 3,3′,4,4′,5-Pentachlorobiphenyl (PCB 126) in Rats
inferredcites →https://doi.org/10.1016/s0896-6273(00)81034-xopenalex-snapshot
Asymmetric Growth and Development of the Xenopus laevis Retina during Metamorphosis Is Controlled by Type III Deiodinase
inferredcites →https://doi.org/10.1016/s1001-0742(10)60408-1openalex-snapshot
In vitro fluorescence displacement investigation of thyroxine transport disruption by bisphenol A
inferredcites →https://doi.org/10.1016/s1001-0742(11)60819-xopenalex-snapshot
Species-dependent effects of the phenolic herbicide ioxynil with potential thyroid hormone disrupting activity: modulation of its cellular uptake and activity by interaction with serum thyroid hormone-binding proteins
inferredcites →https://doi.org/10.1016/s1055-937x(98)80044-3openalex-snapshot
Comparative renal function in reptiles, birds, and mammals
inferredcites →https://doi.org/10.1021/acs.est.7b06145openalex-snapshot
High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library
inferredcites →https://doi.org/10.1021/acs.est.8b00776openalex-snapshot
Thyroid Disruption by Bisphenol S Analogues via Thyroid Hormone Receptor β: in Vitro , in Vivo , and Molecular Dynamics Simulation Study
inferredcites →https://doi.org/10.1021/acs.est.8b03581openalex-snapshot
Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals
inferredcites →https://doi.org/10.1021/acs.est.8b04587openalex-snapshot
Evidence for Cross Species Extrapolation of Mammalian-Based High-Throughput Screening Assay Results
inferredcites →https://doi.org/10.1021/acs.est.9b07204openalex-snapshot
Effect of Thyroperoxidase and Deiodinase Inhibition on Anterior Swim Bladder Inflation in the Zebrafish
inferredcites →https://doi.org/10.1021/acs.est.9b07205openalex-snapshot
Toward an AOP Network-Based Tiered Testing Strategy for the Assessment of Thyroid Hormone Disruption
inferredcites →https://doi.org/10.1021/es0704129openalex-snapshot
An In Vivo Multiwell-Based Fluorescent Screen for Monitoring Vertebrate Thyroid Hormone Disruption
inferredcites →https://doi.org/10.1021/es202248hopenalex-snapshot
Zebrafish Eleutheroembryos Provide a Suitable Vertebrate Model for Screening Chemicals that Impair Thyroid Hormone Synthesis
inferredcites →https://doi.org/10.1021/es2046074openalex-snapshot
Assessment of the Binding of Hydroxylated Polybrominated Diphenyl Ethers to Thyroid Hormone Transport Proteins Using a Site-Specific Fluorescence Probe
inferredcites →https://doi.org/10.1021/es9012454openalex-snapshot
Simple, Rapid Zebrafish Larva Bioassay for Assessing the Potential of Chemical Pollutants and Drugs to Disrupt Thyroid Gland Function
inferredcites →https://doi.org/10.1021/es902691uopenalex-snapshot
Recombinant Albumin and Transthyretin Transport Proteins from Two Gull Species and Human: Chlorinated and Brominated Contaminant Binding and Thyroid Hormones
inferredcites →https://doi.org/10.1023/a:1007722812697openalex-snapshot
Comparative study of iodothyronine outer ring and inner ring deiodinase activities in five teleostean fishes
inferredcites →https://doi.org/10.1038/83829openalex-snapshot
A thyroid hormone receptor that is required for the development of green cone photoreceptors
inferredcites →https://doi.org/10.1038/s41433-018-0288-8openalex-snapshot
From axolotl to zebrafish: a comparative approach to the study of thyroid involvement in ocular development
inferredcites →https://doi.org/10.1038/s41467-020-17450-8openalex-snapshot
Anthropogenic stressors impact fish sensory development and survival via thyroid disruption
inferredcites →https://doi.org/10.1038/sj.cgt.7700525openalex-snapshot
The rat sodium iodide symporter gene permits more effective radioisotope concentration than the human sodium iodide symporter gene in human and rodent cancer cells
inferredcites →https://doi.org/10.1038/sj.emboj.7601356openalex-snapshot
Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development
inferredcites →https://doi.org/10.1039/c3mb70398copenalex-snapshot
Iodotyrosine deiodinase: a unique flavoprotein present in organisms of diverse phyla
inferredcites →https://doi.org/10.1053/j.semperi.2008.09.009openalex-snapshot
The Role of Transient Hypothyroxinemia of Prematurity in Development of Visual Abilities
inferredcites →https://doi.org/10.1055/a-0919-3879openalex-snapshot
Inhibition of Type 1 Iodothyronine Deiodinase by Bisphenol A
inferredcites →https://doi.org/10.1073/pnas.1920086117openalex-snapshot
Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision
inferredcites →https://doi.org/10.1073/pnas.2136755100openalex-snapshot
Thyroid hormone controls the development of connections between the spinal cord and limbs during Xenopus laevis metamorphosis
inferredcites →https://doi.org/10.1074/jbc.272.13.8179openalex-snapshot
Thyroid Hormone-dependent Gene Expression Program for Xenopus Neural Development
inferredcites →https://doi.org/10.1074/jbc.m112.413831openalex-snapshot
Zebrafish as a Model for Monocarboxyl Transporter 8-Deficiency
inferredcites →https://doi.org/10.1074/jbc.m205608200openalex-snapshot
A Thyroid Hormone Antagonist That Inhibits Thyroid Hormone Action in Vivo
inferredcites →https://doi.org/10.1080/00498254.2018.1437300openalex-snapshot
Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats
inferredcites →https://doi.org/10.1080/10408440591007304openalex-snapshot
Mode of Action: Neurotoxicity Induced by Thyroid Hormone Disruption During Development—Hearing Loss Resulting From Exposure to PHAHs
inferredcites →https://doi.org/10.1080/17446651.2022.2044788openalex-snapshot
Impact of endocrine disrupting chemicals on neurodevelopment: the need for better testing strategies for endocrine disruption-induced developmental neurotoxicity
inferredcites →https://doi.org/10.1089/thy.2009.0128openalex-snapshot
Visual Abilities at 6 Months in Preterm Infants: Impact of Thyroid Hormone Deficiency and Neonatal Medical Morbidity
inferredcites →https://doi.org/10.1089/thy.2015.0034openalex-snapshot
Aberrant Cerebellar Development in Mice Lacking Dual Oxidase Maturation Factors
inferredcites →https://doi.org/10.1093/bmb/63.1.39openalex-snapshot
Sensory organ development in the inner ear: molecular and cellular mechanisms
inferredcites →https://doi.org/10.1093/gbe/evw013openalex-snapshot
Contrasting patterns of evolutionary diversification in the olfactory repertoires of reptile and bird genomes
inferredcites →https://doi.org/10.1093/icb/37.6.482openalex-snapshot
Hormonal Mechanisms as Potential Constraints on Evolution: Examples from the Anura
inferredcites →https://doi.org/10.1093/toxsci/kfaa036openalex-snapshot
Targeted Pathway-basedIn VivoTesting Using Thyroperoxidase Inhibition to Evaluate Plasma Thyroxine as a Surrogate Metric of Metamorphic Success in Model AmphibianXenopus laevis
inferredcites →https://doi.org/10.1093/toxsci/kfac014openalex-snapshot
Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development in Xenopus laevis Using Iopanoic Acid
inferredcites →https://doi.org/10.1093/toxsci/kfi049openalex-snapshot
In Vitro and in Vivo Analysis of the Thyroid Disrupting Activities of Phenolic and Phenol Compounds in Xenopus laevis
inferredcites →https://doi.org/10.1093/toxsci/kfj204openalex-snapshot
In Vitro and In Vivo Analysis of the Thyroid System–Disrupting Activities of Brominated Phenolic and Phenol Compounds in Xenopus laevis
inferredcites →https://doi.org/10.1093/toxsci/kfm001openalex-snapshot
Effects of Prolonged Exposure to Perchlorate on Thyroid and Reproductive Function in Zebrafish
inferredcites →https://doi.org/10.1093/toxsci/kfq166openalex-snapshot
Inhibition of Thyroid Hormone Release from Cultured Amphibian Thyroid Glands by Methimazole, 6-Propylthiouracil, and Perchlorate
inferredcites →https://doi.org/10.1093/toxsci/kfr105openalex-snapshot
Accumulation and Debromination of Decabromodiphenyl Ether (BDE-209) in Juvenile Fathead Minnows (Pimephales promelas) Induces Thyroid Disruption and Liver Alterations
inferredcites →https://doi.org/10.1093/toxsci/kfr117openalex-snapshot
Halogenated Phenolic Contaminants Inhibit the In Vitro Activity of the Thyroid-Regulating Deiodinases in Human Liver
inferredcites →https://doi.org/10.1093/toxsci/kfr244openalex-snapshot
Impact of Low-Level Thyroid Hormone Disruption Induced by Propylthiouracil on Brain Development and Function
inferredcites →https://doi.org/10.1093/toxsci/kfs072openalex-snapshot
In Ovo Effects of Perfluorohexane Sulfonate and Perfluorohexanoate on Pipping Success, Development, mRNA Expression, and Thyroid Hormone Levels in Chicken Embryos
inferredcites →https://doi.org/10.1093/toxsci/kfv090openalex-snapshot
In Vitro,Ex Vivo, andIn VivoDetermination of Thyroid Hormone Modulating Activity of Benzothiazoles
inferredcites →https://doi.org/10.1093/toxsci/kfw119openalex-snapshot
Editor’s Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity
inferredcites →https://doi.org/10.1093/toxsci/kfx279openalex-snapshot
Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity
inferredcites →https://doi.org/10.1093/toxsci/kfy016openalex-snapshot
Developmental Thyroid Hormone Insufficiency Induces a Cortical Brain Malformation and Learning Impairments: A Cross-Fostering Study
inferredcites →https://doi.org/10.1093/toxsci/kfy028openalex-snapshot
The Affinity of Brominated Phenolic Compounds for Human and Zebrafish Thyroid Receptor β: Influence of Chemical Structure
inferredcites →https://doi.org/10.1093/toxsci/kfy203openalex-snapshot
Evaluating Iodide Recycling Inhibition as a Novel Molecular Initiating Event for Thyroid Axis Disruption in Amphibians
inferredcites →https://doi.org/10.1093/toxsci/kfy302openalex-snapshot
Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases
inferredcites →https://doi.org/10.1093/toxsci/kfz006openalex-snapshot
Extracting and Benchmarking Emerging Adverse Outcome Pathway Knowledge
inferredcites →https://doi.org/10.1093/toxsci/kfz227openalex-snapshot
Extrapolating In Vitro Screening Assay Data for Thyroperoxidase Inhibition to Predict Serum Thyroid Hormones in the Rat
inferredcites →https://doi.org/10.1096/fj.04-2023fjeopenalex-snapshot
Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site
inferredcites →https://doi.org/10.1096/fj.201600223ropenalex-snapshot
Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis
inferredcites →https://doi.org/10.1097/med.0000000000000275openalex-snapshot
The interaction between thyroid and kidney disease: an overview of the evidence
inferredcites →https://doi.org/10.1098/rspb.2012.2490openalex-snapshot
Opsin switch reveals function of the ultraviolet cone in fish foraging
inferredcites →https://doi.org/10.1098/rspb.2016.1206openalex-snapshot
Thyroid hormone modulates offspring sex ratio in a turtle with temperature-dependent sex determination
inferredcites →https://doi.org/10.1111/j.1749-6632.2008.03652.xopenalex-snapshot
Localization and Enzyme Activity of Iodotyrosine Dehalogenase 1 during Metamorphosis of Frog Microhyla ornata
inferredcites →https://doi.org/10.1111/jne.12169openalex-snapshot
Subcortical Band Heterotopia in Rat Offspring Following Maternal Hypothyroxinaemia: Structural and Functional Characteristics
inferredcites →https://doi.org/10.1111/joa.12314openalex-snapshot
Where hearing starts: the development of the mammalian cochlea
inferredcites →https://doi.org/10.1124/dmd.109.028621openalex-snapshot
4-Hydroxy-2,2′,3,4′,5,5′,6-heptachlorobiphenyl-Mediated Decrease in Serum Thyroxine Level in Mice Occurs through Increase in Accumulation of Thyroxine in the Liver
inferredcites →https://doi.org/10.1124/dmd.121.000498openalex-snapshot
Mechanisms by Which Inducers of Drug Metabolizing Enzymes Alter Thyroid Hormones in Rats
inferredcites →https://doi.org/10.1124/mol.64.2.474openalex-snapshot
The Environmental Pollutant 1,1-Dichloro-2,2-bis (p-chlorophenyl)ethylene Induces Rat Hepatic Cytochrome P450 2B and 3A Expression through the Constitutive Androstane Receptor and Pregnane X Receptor
inferredcites →https://doi.org/10.1126/science.aau6348openalex-snapshot
Thyroid hormone signaling specifies cone subtypes in human retinal organoids
inferredcites →https://doi.org/10.1134/s1062360414060058openalex-snapshot
Effects of thyroid hormone level alterations on the Weberian apparatus ontogeny of cyprinids (Cyprinidae; Teleostei)
inferredcites →https://doi.org/10.1134/s1995082911040067openalex-snapshot
The role of thyroid hormones in the formation of behavioral responses in juvenile roach (Rutilus rutilus (L.) (Cyprinidae)
inferredcites →https://doi.org/10.1152/ajpcell.2000.278.1.c207openalex-snapshot
Human pendrin expressed in Xenopus laevis oocytes mediates chloride/formate exchange
inferredcites →https://doi.org/10.1152/ajpendo.00216.2012openalex-snapshot
Delayed development of specific thyroid hormone-regulated events in transthyretin null mice
inferredcites →https://doi.org/10.1152/ajprenal.00011.2009openalex-snapshot
Developmental delays consistent with cochlear hypothyroidism contribute to failure to develop hearing in mice lacking Slc26a4/pendrin expression
inferredcites →https://doi.org/10.1159/000113336openalex-snapshot
Evolution of Vertebrate Olfactory Systems
inferredcites →https://doi.org/10.1159/000335106openalex-snapshot
Pendrin Function and Regulation in Xenopus Oocytes
inferredcites →https://doi.org/10.1159/000445559openalex-snapshot
Effect of Known Inhibitors of Ion Transport on Pendrin (SLC26A4) Activity in a Human Kidney Cell Line
inferredcites →https://doi.org/10.1159/000504668openalex-snapshot
Evidence for Prenatal Exposure to Thyroid Disruptors and Adverse Effects on Brain Development
inferredcites →https://doi.org/10.1163/156853908792451511openalex-snapshot
Chronic perchlorate exposure impairs stickleback reproductive behaviour and swimming performance
inferredcites →https://doi.org/10.1163/156854297x00076openalex-snapshot
Evolutionary Trends and Possible Origin of the Weberian Apparatus
inferredcites →https://doi.org/10.1172/jci106748openalex-snapshot
Effects of 3-nitro-l-tyrosine on thyroid function in the rat: an experimental model for the dehalogenase defect
inferredcites →https://doi.org/10.1172/jci113479openalex-snapshot
Dual mechanisms of regulation of type I iodothyronine 5'-deiodinase in the rat kidney, liver, and thyroid gland. Implications for the treatment of hyperthyroidism with radiographic contrast agents.
inferredcites →https://doi.org/10.1172/jci26240openalex-snapshot
Type 3 deiodinase is critical for the maturation and function of the thyroid axis
inferredcites →https://doi.org/10.1186/1471-213x-8-101openalex-snapshot
Thyroid hormone components are expressed in three sequential waves during development of the chick retina
inferredcites →https://doi.org/10.1186/1471-2148-8-103openalex-snapshot
Evolution of pharmacologic specificity in the pregnane X receptor
inferredcites →https://doi.org/10.1186/s13044-021-00105-1openalex-snapshot
Associations between maternal urinary iodine assessment, dietary iodine intakes and neurodevelopmental outcomes in the child: a systematic review
inferredcites →https://doi.org/10.1203/01.pdr.0000157681.38042.b4openalex-snapshot
Development of Contrast Sensitivity in Infants with Prenatal and Neonatal Thyroid Hormone Insufficiencies
inferredcites →https://doi.org/10.1210/en.130.3.1525openalex-snapshot
Thyroxine (T4) transport and distribution in rats treated with EMD 21388, a synthetic flavonoid that displaces T4 from transthyretin
inferredcites →https://doi.org/10.1210/en.2002-220971openalex-snapshot
The Porcine Sodium/Iodide Symporter Gene Exhibits an Uncommon Expression Pattern Related to the Use of Alternative Splice Sites not Present in the Human or Murine Species
inferredcites →https://doi.org/10.1210/en.2005-0711openalex-snapshot
Characterization of Recombinant Xenopus laevis Type I Iodothyronine Deiodinase: Substitution of a Proline Residue in the Catalytic Center by Serine (Pro132Ser) Restores Sensitivity to 6-Propyl-2-Thiouracil
inferredcites →https://doi.org/10.1210/en.2005-0739openalex-snapshot
Targeted Disruption of the Type 1 Selenodeiodinase Gene (Dio1) Results in Marked Changes in Thyroid Hormone Economy in Mice
inferredcites →https://doi.org/10.1210/en.2006-1727openalex-snapshot
Thyroid Hormone Homeostasis and Action in the Type 2 Deiodinase-Deficient Rodent Brain during Development
inferredcites →https://doi.org/10.1210/en.2008-1092openalex-snapshot
Retarded Developmental Expression and Patterning of Retinal Cone Opsins in Hypothyroid Mice
inferredcites →https://doi.org/10.1210/en.2008-1419openalex-snapshot
A Protective Role for Type 3 Deiodinase, a Thyroid Hormone-Inactivating Enzyme, in Cochlear Development and Auditory Function
inferredcites →https://doi.org/10.1210/en.2008-1437openalex-snapshot
The Sodium-Iodide Symporter NIS and Pendrin in Iodide Homeostasis of the Thyroid
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Hepatic enzyme induction and its potential effect on thyroid hormone metabolism in the metamorphosing tadpole of Xenopus laevis (African clawed frog)
inferred← citeshttps://doi.org/10.1007/s00204-024-03766-7openalex-snapshot
In vitro assessment of thyroid peroxidase inhibition by chemical exposure: comparison of cell models and detection methods
inferred← citeshttps://doi.org/10.1007/s00204-025-04034-yopenalex-snapshot
Advancing in vitro assessment of iodide uptake inhibition: integrating a novel biotransformation pretreatment step
inferred← citeshttps://doi.org/10.1007/s00204-025-04258-yopenalex-snapshot
In vitro thyroperoxidase inhibition assessment by LC-ICP-MS-based L-tyrosine iodination assay: comparison with Amplex Ultrared assay and its modifications
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Environmental exposure to dinotefuran disturbs circadian rhythm, thyroid hormones and neurotransmitters, leading to locomotor deficits in Opsariichthys bidens larvae
inferred← citeshttps://doi.org/10.1016/j.cotox.2026.100600openalex-snapshot
Are thyroid hormone–mediated mechanisms an overlooked pathway in male reproductive toxicity?
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.116995openalex-snapshot
The thyroid hormone system disrupting potential of resorcinol in fish
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The antithyroid drug methimazole as an emerging aquatic contaminant: Physiological and reproductive disruption in female goldfish (Carassius auratus) and partial mitigation by thyroxine
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Adverse outcome pathway-oriented exploration of neurodevelopmental toxicity of tris(1,3-dichloropropyl) phosphate linked to membrane thyroid hormone receptor activation
inferred← citeshttps://doi.org/10.1016/j.envint.2026.110451openalex-snapshot
Adverse outcome pathway network-based approach for the evaluation of thyroid hormone system disruption for human health and environmental regulatory hazard assessment
inferred← citeshttps://doi.org/10.1016/j.envint.2026.110465openalex-snapshot
Mapping disease-linked AOPs to inform bioassay selection for chemical hazard assessment
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.139890openalex-snapshot
Impact of nanoplastics on thyroid function: Unraveling cellular biokinetics, molecular mechanisms and human risk assessment
inferred← citeshttps://doi.org/10.1016/j.namjnl.2026.100093openalex-snapshot
Use of New Approach Methodologies for the assessment of Endocrine Disruption within European union regulatory frameworks: Report from the 2024 European partnership for alternative approaches (EPAA) partners’ forum
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.170968openalex-snapshot
An integrative data-centric approach to derivation and characterization of an adverse outcome pathway network for cadmium-induced toxicity
inferred← citeshttps://doi.org/10.1016/j.tox.2024.153794openalex-snapshot
Exploring a mechanism-based approach for the identification of endocrine disruptors using Adverse Outcome Pathways (AOPs) and New Approach Methodologies (NAMs) : A perfluorooctane sulfonic acid case study
inferred← citeshttps://doi.org/10.1016/j.tox.2025.154337openalex-snapshot
Ophthalmotoxicology of polyhalogenated compounds
inferred← citeshttps://doi.org/10.1016/j.tox.2026.154542openalex-snapshot
Integrating transcriptomics and molecular AOPs to identify T3-dependent regulation of neuronal development in the human neural progenitor test
inferred← citeshttps://doi.org/10.1016/j.yrtph.2025.105810openalex-snapshot
Cross-taxa extrapolation: Is there a role for thyroid hormone conjugating liver enzymes during amphibian metamorphosis?
inferred← citeshttps://doi.org/10.1071/en23105openalex-snapshot
Developing a modern approach to assess ecological risk from pesticides without unnecessary vertebrate animal testing
inferred← citeshttps://doi.org/10.1080/10408444.2026.2623026openalex-snapshot
Role of constitutive androstane receptor in developmental toxicology: linking chemical exposure, nutrition, and disease susceptibility
inferred← citeshttps://doi.org/10.1093/etojnl/vgaf031openalex-snapshot
Developing adverse outcome pathways to support radioecological risk assessment: challenges and insights
inferred← citeshttps://doi.org/10.1093/inteam/vjag058openalex-snapshot
Best practices for the development and application of bioinformatics approaches for species extrapolation in chemical safety assessment
inferred← citeshttps://doi.org/10.1111/brv.70106openalex-snapshot
Prioritising research on endocrine disruption in the marine environment: a global perspective
inferred← citeshttps://doi.org/10.2903/j.efsa.2023.e211005openalex-snapshot
Toxicometabolomics as a tool for next generation environmental risk assessment
inferred← citeshttps://doi.org/10.2903/j.efsa.2024.8672openalex-snapshot
Specific effects on the thyroid relevant for performing a dietary cumulative risk assessment of pesticide residues: 2024 update
inferred← citeshttps://doi.org/10.2903/j.efsa.2025.9711openalex-snapshot
Peer review of the pesticide risk assessment of the active substance phenmedipham
inferred← citeshttps://doi.org/10.3389/fphar.2026.1760820openalex-snapshot
Epidemiological relevant effect biomarkers for thyroid hormone system related adverse outcome pathways: a literature review
inferred← citeshttps://doi.org/10.3389/ftox.2024.1285768openalex-snapshot
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps
inferred← citeshttps://doi.org/10.3389/ftox.2026.1733477openalex-snapshot
Zebrafish neuromast development: a target for endocrine disrupting chemicals?
inferred← citeshttps://doi.org/10.3389/ftox.2026.1736963openalex-snapshot
New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption – a PARC project
inferred← citeshttps://doi.org/10.3390/jox16050164openalex-snapshot
Selenium and Iodine as Susceptibility Modifiers of Thyroid Disruption Associated with Metals: An Overview of Human and Experimental Research Data
inferred← citeshttps://doi.org/10.3390/toxics13070590openalex-snapshot
New QSAR Models to Predict Human Transthyretin Disruption by Per- and Polyfluoroalkyl Substances (PFAS): Development and Application
inferred← citeshttps://doi.org/10.64898/2026.06.25.734475openalex-snapshot
Integrating Semantic Retrieval, LLM-based Refinement, and Structured Expert Curation for Scalable AOP Gene Mapping
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