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Fundamental constraints to the logic of living systems
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Darwin's dangerous idea
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Microbial growth by a net heat up‐take: A calorimetric and thermodynamic study on acetotrophic methanogenesis by Methanosarcina barkeri
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In search of a thermodynamic description of biomass yields for the chemotrophic growth of microorganisms
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Energy flow and the organization of life
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A structural approach for understanding multispecies coexistence
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Oscillations and Chaos in Ant Societies
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Percolation on the Fitness Hypercube and the Evolution of Reproductive Isolation
inferredcites →https://doi.org/10.1006/jtbi.1998.0771openalex-snapshot
Shaping Space: the Possible and the Attainable in RNA Genotype–phenotype Mapping
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The Protein Folds as Platonic Forms: New Support for the Pre-Darwinian Conception of Evolution by Natural Law
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Introduction to Artificial Life
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The Algorithmic Beauty of Plants
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Mathematical Modeling of Biological Pattern Formation
inferredcites →https://doi.org/10.1007/978-3-319-15045-1_6openalex-snapshot
Networks and Hierarchies: Approaching Complexity in Evolutionary Theory
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On the Origin of Phosphorylated Biomolecules
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Synergetics: Introduction and Advanced Topics
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Brain Evolution as an Information Flow Designer: The Ground Architecture for Biological and Artificial General Intelligence
inferredcites →https://doi.org/10.1007/978-94-010-2091-6_2openalex-snapshot
The Second Law of Thermodynamics
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From genes to phenotype: dynamical systems and evolvability
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A mechanical model for epithelial morphogenesis
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Neocognitron: A self-organizing neural network model for a mechanism of pattern recognition unaffected by shift in position
inferredcites →https://doi.org/10.1007/bf00450633openalex-snapshot
A principle of natural self-organization
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Statistical mechanics of Eigen's evolution model
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Numerical testing of evolution theories
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The thermodynamics of computation—a review
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The chemical basis of morphogenesis
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Some order-disorder considerations in living systems
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A logical calculus of the ideas immanent in nervous activity
inferredcites →https://doi.org/10.1007/s00239-018-9876-2openalex-snapshot
Folding, Assembly, and Persistence: The Essential Nature and Origins of Biopolymers
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The Multiple Paths to Multiple Life
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Generalized Stoichiometry and Biogeochemistry for Astrobiological Applications
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Convergent Evolutionary Paths in Biological and Technological Networks
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Physical and Functional Conditions for Symbols, Codes, and Languages
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Heat transfer through a shallow, horizontal convecting fluid layer
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The origin of the genetic code
inferredcites →https://doi.org/10.1016/0022-5193(66)90007-5openalex-snapshot
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The logical analysis of continuous, non-linear biochemical control networks
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Self-reproduction in cellular automata
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The coreworld: Emergence and evolution of cooperative structures in a computational chemistry
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Co-evolving parasites improve simulated evolution as an optimization procedure
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Random catalytic reaction networks
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Evolution, complexity, entropy and artificial reality
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Open systems living in a closed biosphere: a new paradox for the Gaia debate
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The renormalization group and the ε expansion
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Phenomenological Lagrangians
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Renormalization and effective lagrangians
inferredcites →https://doi.org/10.1016/b978-0-08-010586-4.50034-1openalex-snapshot
ON THE THEORY OF PHASE TRANSITIONS
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How Does a Molecule Become a Message?
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Turnstiles and bifurcators: The disequilibrium converting engines that put metabolism on the road
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Unjamming and collective migration in MCF10A breast cancer cell lines
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Evolution and self-assembly of protocells
inferredcites →https://doi.org/10.1016/j.biosystems.2014.03.004openalex-snapshot
Prolegomenon to patterns in evolution
inferredcites →https://doi.org/10.1016/j.ceb.2021.07.011openalex-snapshot
Jamming and arrest of cell motion in biological tissues
inferredcites →https://doi.org/10.1016/j.cell.2021.02.017openalex-snapshot
Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions
inferredcites →https://doi.org/10.1016/j.coisb.2017.11.007openalex-snapshot
The road to synthetic multicellularity
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Exploring alternative states in ecological systems with a qualitative analysis of community feedback
inferredcites →https://doi.org/10.1016/j.gde.2012.11.013openalex-snapshot
Turing patterns in development: what about the horse part?
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Synthetic living machines: A new window on life
inferredcites →https://doi.org/10.1016/j.jtbi.2004.04.027openalex-snapshot
Forest gap dynamics and the Ising model
inferredcites →https://doi.org/10.1016/j.jtbi.2005.08.038openalex-snapshot
The evolution of information in the major transitions
inferredcites →https://doi.org/10.1016/j.jtbi.2006.10.021openalex-snapshot
Protocell self-reproduction in a spatially extended metabolism–vesicle system
inferredcites →https://doi.org/10.1016/j.jtbi.2007.07.029openalex-snapshot
A model for the emergence of the genetic code as a transition in a noisy information channel
inferredcites →https://doi.org/10.1016/j.jtbi.2010.06.017openalex-snapshot
The evolution of associative learning: A factor in the Cambrian explosion
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Evolutionary construction by staying together and coming together
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Anergy in self-directed B lymphocytes: A statistical mechanics perspective
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The large deviation approach to statistical mechanics
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Escapement mechanisms and the conversion of disequilibria; the engines of creation
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From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics
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Rigidity transitions in development and disease
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Collective cognition in animal groups
inferredcites →https://doi.org/10.1016/j.tree.2006.04.007openalex-snapshot
Is a healthy ecosystem one that is rich in parasites?
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Maximum information entropy: a foundation for ecological theory
inferredcites →https://doi.org/10.1016/j.tree.2020.07.013openalex-snapshot
Evolution of Cellular Differentiation: From Hypotheses to Models
inferredcites →https://doi.org/10.1016/j.virusres.2006.01.010openalex-snapshot
The origin of viruses and their possible roles in major evolutionary transitions
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The logic of monsters: Evidence for internal constraint in development and evolution
inferredcites →https://doi.org/10.1016/s0022-5193(05)80391-1openalex-snapshot
A connectionist model of development
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Adhesion-guided multicellular assembly: a commentary upon the postulates, real and imagined, of the differential adhesion hypothesis, with special attention to computer simulations of cell sorting
inferredcites →https://doi.org/10.1016/s0022-5193(86)80047-9openalex-snapshot
Autocatalytic sets of proteins
inferredcites →https://doi.org/10.1016/s0169-5347(02)02612-5openalex-snapshot
The biology of digital organisms
inferredcites →https://doi.org/10.1016/s0301-4622(00)00122-8openalex-snapshot
Natural selection: a phase transition?
inferredcites →https://doi.org/10.1016/s0301-4622(97)00058-6openalex-snapshot
Genotypes with phenotypes: Adventures in an RNA toy world
inferredcites →https://doi.org/10.1016/s0303-2647(01)00110-1openalex-snapshot
Evolution with material symbol systems
inferredcites →https://doi.org/10.1016/s0303-2647(01)00130-7openalex-snapshot
Origins of life: a route to nanotechnology
inferredcites →https://doi.org/10.1016/s0303-2647(98)00034-3openalex-snapshot
Metabolism and the problem of its universalization
inferredcites →https://doi.org/10.1016/s0896-6273(01)00542-6openalex-snapshot
Rate, Timing, and Cooperativity Jointly Determine Cortical Synaptic Plasticity
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The Quest for a Universal Theory of Life: Searching for Life as We Don't Know It
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Life's Information Hierarchy
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Information Theory, Evolution, and the Origin of Life
inferredcites →https://doi.org/10.1017/cbo9780511660108.006openalex-snapshot
The Ising model, computer simulation, and universal physics
inferredcites →https://doi.org/10.1017/cbo9780511755576openalex-snapshot
Biological Physics of the Developing Embryo
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Emergent order in processes: the interplay of complexity, robustness, correlation, and hierarchy in the biosphere
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The Origin and Nature of Life on Earth: The Emergence of the Fourth Geosphere
inferredcites →https://doi.org/10.1017/pab.2014.2openalex-snapshot
Was the Ediacaran–Cambrian radiation a unique evolutionary event?
inferredcites →https://doi.org/10.1017/s0024282921000256openalex-snapshot
Lichens and microbial syntrophies offer models for an interdependent route to multicellularity
inferredcites →https://doi.org/10.1017/s0033583500000615openalex-snapshot
Biological order, structure and instabilities
inferredcites →https://doi.org/10.1021/cr2004844openalex-snapshot
Prebiotic Systems Chemistry: New Perspectives for the Origins of Life
inferredcites →https://doi.org/10.1023/a:1006611022472openalex-snapshot
Complexity versus Uncertainty: The Question of Staying Alive
inferredcites →https://doi.org/10.1023/a:1006616725062openalex-snapshot
Self-programmable, Self-assembling Two-dimensional Genetic Matter
inferredcites →https://doi.org/10.1023/b:orig.0000016440.53346.dcopenalex-snapshot
A Universal Definition of Life: Autonomy and Open-Ended Evolution
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The First Computational Theory of Mind and Brain: A Close Look at Mcculloch and Pitts's “Logical Calculus of Ideas Immanent in Nervous Activity”
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Ecosystem functioning and intrinsic value of biodiversity
inferredcites →https://doi.org/10.1038/150563a0openalex-snapshot
CANALIZATION OF DEVELOPMENT AND THE INHERITANCE OF ACQUIRED CHARACTERS
inferredcites →https://doi.org/10.1038/171737a0openalex-snapshot
Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid
inferredcites →https://doi.org/10.1038/172156a0openalex-snapshot
Evidence for 2-Chain Helix in Crystalline Structure of Sodium Deoxyribonucleate
inferredcites →https://doi.org/10.1038/1831654a0openalex-snapshot
Canalization of Development and Genetic Assimilation of Acquired Characters
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Will a Large Complex System be Stable?
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Chance and necessity: the evolution of morphological complexity and diversity
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The consequences of political dictatorship for Russian science
inferredcites →https://doi.org/10.1038/ismej.2016.21openalex-snapshot
Evolutionary tradeoffs in cellular composition across diverse bacteria
inferredcites →https://doi.org/10.1038/msb.2010.74openalex-snapshot
An atlas of gene regulatory networks reveals multiple three‐gene mechanisms for interpreting morphogen gradients
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The imitation game—a computational chemical approach to recognizing life
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Origins of multicellular evolvability in snowflake yeast
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A density-independent rigidity transition in biological tissues
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The origin of Metazoa: a unicellular perspective
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Identifying molecules as biosignatures with assembly theory and mass spectrometry
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Sculpting tissues by phase transitions
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Assessing planetary complexity and potential agnostic biosignatures using epsilon machines
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More is different in real-world multilayer networks
inferredcites →https://doi.org/10.1038/s41567-023-02330-xopenalex-snapshot
Diversity of information pathways drives sparsity in real-world networks
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Self-reproducing catalytic micelles as nanoscopic protocell precursors
inferredcites →https://doi.org/10.1038/s41576-019-0175-6openalex-snapshot
Building machines with DNA molecules
inferredcites →https://doi.org/10.1038/s41580-020-00318-6openalex-snapshot
Programmed and self-organized flow of information during morphogenesis
inferredcites →https://doi.org/10.1038/s41586-023-06600-9openalex-snapshot
Assembly theory explains and quantifies selection and evolution
inferredcites →https://doi.org/10.1038/s42003-024-06037-4openalex-snapshot
Collective intelligence: A unifying concept for integrating biology across scales and substrates
inferredcites →https://doi.org/10.1038/s42254-023-00676-yopenalex-snapshot
Robustness and resilience of complex networks
inferredcites →https://doi.org/10.1038/s44222-022-00001-9openalex-snapshot
Synthetic morphology with agential materials
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The Fundamental Physical Limits of Computation
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Problems in Physics with many Scales of Length
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Achievements and open questions in the self-reproduction of vesicles and synthetic minimal cells
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Out of fuzzy chemistry: from prebiotic chemistry to metabolic networks
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A morphospace for synthetic organs and organoids: the possible and the actual
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On Symmetry-Breaking Instabilities in Dissipative Systems
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An exact correspondence between Eigen’s evolution model and a two-dimensional Ising system
inferredcites →https://doi.org/10.1063/1.4818538openalex-snapshot
Statistical physics of self-replication
inferredcites →https://doi.org/10.1073/pnas.0404922101openalex-snapshot
Universality in intermediary metabolism
inferredcites →https://doi.org/10.1073/pnas.0603780103openalex-snapshot
Collective evolution and the genetic code
inferredcites →https://doi.org/10.1073/pnas.0701489104openalex-snapshot
Evolution of individuality during the transition from unicellular to multicellular life
inferredcites →https://doi.org/10.1073/pnas.0705653104openalex-snapshot
Social cheating in Pseudomonas aeruginosa quorum sensing
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Prevolutionary dynamics and the origin of evolution
inferredcites →https://doi.org/10.1073/pnas.0912628107openalex-snapshot
Lack of evolvability in self-sustaining autocatalytic networks constraints metabolism-first scenarios for the origin of life
inferredcites →https://doi.org/10.1073/pnas.1007783107openalex-snapshot
Shifts in metabolic scaling, production, and efficiency across major evolutionary transitions of life
inferredcites →https://doi.org/10.1073/pnas.1115323109openalex-snapshot
Experimental evolution of multicellularity
inferredcites →https://doi.org/10.1073/pnas.1115585109openalex-snapshot
Growth, metabolic partitioning, and the size of microorganisms
inferredcites →https://doi.org/10.1073/pnas.1202196109openalex-snapshot
Late Cretaceous restructuring of terrestrial communities facilitated the end-Cretaceous mass extinction in North America
inferredcites →https://doi.org/10.1073/pnas.1300832110openalex-snapshot
On the origins of hierarchy in complex networks
inferredcites →https://doi.org/10.1073/pnas.1304196111openalex-snapshot
Exploring exoplanet populations with NASA’s Kepler Mission
inferredcites →https://doi.org/10.1073/pnas.1304212111openalex-snapshot
Requirements and limits for life in the context of exoplanets
inferredcites →https://doi.org/10.1073/pnas.1408542111openalex-snapshot
Fractal branching organizations of Ediacaran rangeomorph fronds reveal a lost Proterozoic body plan
inferredcites →https://doi.org/10.1073/pnas.1421398112openalex-snapshot
Toward major evolutionary transitions theory 2.0
inferredcites →https://doi.org/10.1073/pnas.1421402112openalex-snapshot
Major evolutionary transitions in individuality
inferredcites →https://doi.org/10.1073/pnas.152302199openalex-snapshot
Spatial patterns in ant colonies
inferredcites →https://doi.org/10.1073/pnas.1704631114openalex-snapshot
On the origin of biological construction, with a focus on multicellularity
inferredcites →https://doi.org/10.1073/pnas.1807890115openalex-snapshot
Physical foundations of biological complexity
inferredcites →https://doi.org/10.1073/pnas.2106655119openalex-snapshot
Scaling laws in enzyme function reveal a new kind of biochemical universality
inferredcites →https://doi.org/10.1073/pnas.2220022120openalex-snapshot
Turing, von Neumann, and the computational architecture of biological machines
inferredcites →https://doi.org/10.1073/pnas.2307149120openalex-snapshot
A robust, agnostic molecular biosignature based on machine learning
inferredcites →https://doi.org/10.1073/pnas.2312521121openalex-snapshot
Structured community transitions explain the switching capacity of microbial systems
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Modern metabolism as a palimpsest of the RNA world.
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What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/s10441-026-09541-8openalex-snapshot
Balance Between Order and Disorder: Quantum-Epigenetic Pathways for the Emergence and Continuous Evolution of Life
inferred← citeshttps://doi.org/10.1007/s11229-026-05512-1openalex-snapshot
Probabilistic epigenetics: an informational approach
inferred← citeshttps://doi.org/10.1007/s13762-025-06893-5openalex-snapshot
The underlying dynamic moving life and its evolution is a prigoginean dissipative system of informational nature
inferred← citeshttps://doi.org/10.1016/j.coisb.2026.100588openalex-snapshot
Toward a systems view of life’s origins: Modeling the emergence of complexity across chemical, informational and ecological levels
inferred← citeshttps://doi.org/10.1016/j.plrev.2026.08.009openalex-snapshot
Networks as adaptive architectures of living systems, beyond static graphs: Comment on “beyond networks: Toward adaptive models of biological complexity” by Pessoa
inferred← citeshttps://doi.org/10.1038/s41540-024-00477-8openalex-snapshot
Open problems in synthetic multicellularity
inferred← citeshttps://doi.org/10.1038/s44260-025-00049-9openalex-snapshot
Assembly theory and its relationship with computational complexity
inferred← citeshttps://doi.org/10.1038/s44260-025-00063-xopenalex-snapshot
Latent geometry emerging from network-driven processes
inferred← citeshttps://doi.org/10.1038/s44318-026-00692-5openalex-snapshot
A smartphone analogy to explore the origin of animals
inferred← citeshttps://doi.org/10.1073/pnas.2507932123openalex-snapshot
Estimating the amount of computation done by a brain using population neural activity
inferred← citeshttps://doi.org/10.1073/pnas.2532420123openalex-snapshot
Cell division sets a universal flow geometry in cell layers
inferred← citeshttps://doi.org/10.1080/07391102.2026.2719002openalex-snapshot
Genome organization and packaging, mutation impacts and quasi-periodic patterns in viral genomes
inferred← citeshttps://doi.org/10.1098/rsfs.2025.0026openalex-snapshot
Evolution in space: experimental pathways to understanding life’s adaptability beyond Earth
inferred← citeshttps://doi.org/10.1098/rsif.2025.0838openalex-snapshot
Tuning regimes in ant foraging dynamics depend on the existence of bistability
inferred← citeshttps://doi.org/10.1098/rstb.2024.0281openalex-snapshot
Origins of life: the possible and the actual
inferred← citeshttps://doi.org/10.1098/rstb.2024.0295openalex-snapshot
Bifurcations and phase transitions in the origins of life
inferred← citeshttps://doi.org/10.1098/rstb.2024.0297openalex-snapshot
How hard is it to encapsulate life? The general constraints on encapsulation
inferred← citeshttps://doi.org/10.1101/2025.01.13.632745openalex-snapshot
Life as a Function: Why Transformer Architectures Struggle to Gain Genome-Level Foundational Capabilities
inferred← citeshttps://doi.org/10.1101/2025.01.20.633545openalex-snapshot
Discovery of single-stranded DNA in meteorite-derived cultures: evidence of novel genetic elements
inferred← citeshttps://doi.org/10.1101/2025.06.20.660822openalex-snapshot
Convergent Functional Constraints Make Biochemical Reaction Diversity Predictable
inferred← citeshttps://doi.org/10.1101/2025.07.14.664758openalex-snapshot
Linking power, efficiency, and bifurcations in consumer–resource systems
inferred← citeshttps://doi.org/10.1101/2025.10.20.683547openalex-snapshot
On the energetic boundaries of trophic systems
inferred← citeshttps://doi.org/10.1101/2025.11.06.686202openalex-snapshot
Metabolic fluctuations explain allometric scaling diversity
inferred← citeshttps://doi.org/10.1103/rsx4-8x5fopenalex-snapshot
Physics of Life: Exploring Information as a Distinctive Feature of Living Systems
inferred← citeshttps://doi.org/10.1126/sciadv.aea6945openalex-snapshot
Mapping life’s disparity and evolutionary constraints in a geometric complexity space
inferred← citeshttps://doi.org/10.1134/s1062359025612807openalex-snapshot
Towards a Post-Cladistic Biological Systematics: Some Conceptual-Historical Reflections
inferred← citeshttps://doi.org/10.11648/j.sjams.20251305.12openalex-snapshot
Properties of a System of Diophantine Equations with Implications for Real-World Constrained Branching Processes
inferred← citeshttps://doi.org/10.1177/15311074261464011openalex-snapshot
Can Pareto Optimality Be Evidence of Life?
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1014330openalex-snapshot
Energetic constraints shape the diversity of feasible ecological networks
inferred← citeshttps://doi.org/10.3390/biology15070579openalex-snapshot
Unveiling Emergence and Holism in Biology: Essential Insights from Self-Organization
inferred← citeshttps://doi.org/10.3390/systems14030230openalex-snapshot
Some Additional Principles of Living Systems Functioning and Their Application for Expanding the Theory of a Possible Typology of National Food Systems Strategies
inferred← citeshttps://doi.org/10.64898/2026.01.19.700411openalex-snapshot
Information neutrality generates robust biological scaling in stochastic systems
inferred← citeshttps://doi.org/10.64898/2026.05.07.723461openalex-snapshot
Ecological constraints to mirror life
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