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Bridging the Genotype and the Phenotype: Towards An Epigenetic Landscape Approach to Evolutionary Systems Biology
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Journal of Experimental Zoology Part B: Molecular and Developmental Evolution
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Characterization of stem cells and cancer cells on the basis of gene expression profile stability, plasticity, and robustness
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The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post‐Darwinian biology?
inferredcites →https://doi.org/10.1002/jez.b.22468openalex-snapshot
The Inheritance of Process: A Dynamical Systems Approach
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Dynamics of the Genetic Regulatory Network forArabidopsis thalianaFlower Morphogenesis
inferredcites →https://doi.org/10.1007/978-0-387-30440-3_79openalex-snapshot
Complex Gene Regulatory Networks – from Structure to Biological Observables: Cell Fate Determination
inferredcites →https://doi.org/10.1007/978-1-4614-3567-9openalex-snapshot
Evolutionary Systems Biology
inferredcites →https://doi.org/10.1007/978-1-4614-9408-9_26openalex-snapshot
Gene Regulatory Network Models for Floral Organ Determination
inferredcites →https://doi.org/10.1007/bf00123979openalex-snapshot
From genes to phenotype: dynamical systems and evolvability
inferredcites →https://doi.org/10.1007/springerreference_60251openalex-snapshot
Complex Gene Regulatory Networks - from Structure to Biological Observables: Cell Fate Determination
inferredcites →https://doi.org/10.1016/0020-711x(94)90119-8openalex-snapshot
The origins of order; self organization and selection in evolution
inferredcites →https://doi.org/10.1016/b978-0-12-405926-9.00012-5openalex-snapshot
Discrete Gene Network Models for Understanding Multicellularity and Cell Reprogramming: From Network Structure to Attractor Landscapes Landscape
inferredcites →https://doi.org/10.1016/j.cbpa.2010.06.004openalex-snapshot
The origins of evolutionary innovation
inferredcites →https://doi.org/10.1016/j.jtbi.2010.03.006openalex-snapshot
The Arabidopsis thaliana flower organ specification gene regulatory network determines a robust differentiation process
inferredcites →https://doi.org/10.1016/j.pbi.2012.11.005openalex-snapshot
Dynamic models of epidermal patterning as an approach to plant eco-evo-devo
inferredcites →https://doi.org/10.1016/j.pbiomolbio.2012.08.016openalex-snapshot
Rethinking the (im)possible in evolution
inferredcites →https://doi.org/10.1016/j.semcdb.2009.11.010openalex-snapshot
From ABC genes to regulatory networks, epigenetic landscapes and flower morphogenesis: Making biological sense of theoretical approaches
inferredcites →https://doi.org/10.1038/ncomms3467openalex-snapshot
Non-Darwinian dynamics in therapy-induced cancer drug resistance
inferredcites →https://doi.org/10.1073/pnas.0701072104openalex-snapshot
Darwin's greatest discovery: Design without designer
inferredcites →https://doi.org/10.1073/pnas.0906183107openalex-snapshot
Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease
inferredcites →https://doi.org/10.1093/acprof:oso/9780190490447.003.0017openalex-snapshot
The Genotype/Phenotype Distinction
inferredcites →https://doi.org/10.1093/acprof:oso/9780199692590.001.0001openalex-snapshot
The Origins of Evolutionary Innovations
inferredcites →https://doi.org/10.1093/molbev/mst223openalex-snapshot
Molecular Evolution Constraints in the Floral Organ Specification Gene Regulatory Network Module across 18 Angiosperm Genomes
inferredcites →https://doi.org/10.1098/rsif.2013.0787openalex-snapshot
Quantifying Waddington landscapes and paths of non-adiabatic cell fate decisions for differentiation, reprogramming and transdifferentiation
inferredcites →https://doi.org/10.1098/rspb.1979.0086openalex-snapshot
The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme
inferredcites →https://doi.org/10.1098/rstb.2011.0008openalex-snapshot
Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways
inferredcites →https://doi.org/10.1103/physrevlett.94.128701openalex-snapshot
Cell Fates as High-Dimensional Attractor States of a Complex Gene Regulatory Network
inferredcites →https://doi.org/10.1105/tpc.104.021725openalex-snapshot
A Gene Regulatory Network Model for Cell-Fate Determination during Arabidopsis thaliana Flower Development That Is Robust and Recovers Experimental Gene Expression Profiles[W]
inferredcites →https://doi.org/10.1111/j.1558-5646.1975.tb00851.xopenalex-snapshot
THE GENETIC BASIS OF EVOLUTIONARY CHANGE
inferredcites →https://doi.org/10.1126/science.1235294openalex-snapshot
Emergence of Individuality in Genetically Identical Mice
inferredcites →https://doi.org/10.1126/science.42.1074.161openalex-snapshot
The Proceedings of the National Academy of Sciences
inferredcites →https://doi.org/10.1142/9789814415743_0003openalex-snapshot
The Origins of Order: Self-Organization and Selection in Evolution
inferredcites →https://doi.org/10.1145/544220.544327openalex-snapshot
Stanford encyclopedia of philosophy
inferredcites →https://doi.org/10.1162/artl.1995.2.2.261openalex-snapshot
Darwinism Evolving: Systems Dynamics and the Genealogy of Natural Selection.
inferredcites →https://doi.org/10.1162/biot.2008.3.3.224openalex-snapshot
Waddington’s Unfinished Critique of Neo-Darwinian Genetics: Then and Now
inferredcites →https://doi.org/10.1242/dev.035139openalex-snapshot
Non-genetic heterogeneity of cells in development: more than just noise
inferredcites →https://doi.org/10.1371/journal.pbio.1001296openalex-snapshot
Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer
inferredcites →https://doi.org/10.1371/journal.pcbi.1003026openalex-snapshot
Cell Patterns Emerge from Coupled Chemical and Physical Fields with Cell Proliferation Dynamics: The Arabidopsis thaliana Root as a Study System
inferredcites →https://doi.org/10.1371/journal.pone.0003626openalex-snapshot
Floral Morphogenesis: Stochastic Explorations of a Gene Network Epigenetic Landscape
inferredcites →https://doi.org/10.1371/journal.pone.0013523openalex-snapshot
Flower Development as an Interplay between Dynamical Physical Fields and Genetic Networks
inferredcites →https://doi.org/10.1371/journal.pone.0061178openalex-snapshot
Mechanistic Explanations for Restricted Evolutionary Paths That Emerge from Gene Regulatory Networks
inferredcites →https://doi.org/10.1371/journal.pone.0086635openalex-snapshot
The Arrival of the Frequent: How Bias in Genotype-Phenotype Maps Can Steer Populations to Local Optima
inferredcites →https://doi.org/10.1564/23feb12openalex-snapshot
Evolution-A View from the 21st Century
inferredcites →https://doi.org/10.2307/2485224openalex-snapshot
On the Origin of Species by Means of Natural Selection
inferredcites →https://doi.org/10.2976/1.2749445openalex-snapshot
Phenotypic evolution is restrained by complex developmental processes
inferredcites →https://doi.org/10.4171/057-1/14openalex-snapshot
Boltzmann and evolution: some basic questions of biology seen with atomistic glasses
inferredcites →https://doi.org/10.5860/choice.44-4439openalex-snapshot
Evolutionary dynamics: exploring the equations of life
inferredcites →https://doi.org/10.5860/choice.45-1451openalex-snapshot
Biological emergences: evolution by natural experiment
inferredcites →https://doi.org/10.5860/choice.49-3845openalex-snapshot
The logic of chance: the nature and origin of biological evolution
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/dvdy.24268openalex-snapshot
Role of transcriptional regulation in the evolution of plant phenotype: A dynamic systems approach
inferred← citeshttps://doi.org/10.1111/jcpp.13372openalex-snapshot
Annual Research Review: Anterior Modifiers in the Emergence of Neurodevelopmental Disorders (AMEND)—a systems neuroscience approach to common developmental disorders
inferred← citeshttps://doi.org/10.20944/preprints201809.0566.v1openalex-snapshot
Perspectives from Montiaceae (Portulacineae) Evolution. II. Ecological Evolution, Phylogenetic Comparative Analysis, and the Principle of Evolutionary Idiosyncraticity
inferred← citeshttps://doi.org/10.3389/fgene.2017.00045openalex-snapshot
Finding a Needle in a Haystack: Distinguishing Mexican Maize Landraces Using a Small Number of SNPs
inferred← citeshttps://doi.org/10.48550/arxiv.1604.02208openalex-snapshot
Dynamic network and epigenetic landscape model of a regulatory core underlying spontaneous immortalization and epithelial carcinogenesis
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