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Ancestry Composition: A Novel, Efficient Pipeline for Ancestry Deconvolution

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/11415770_30openalex-snapshot
Learning Interpretable SVMs for Biological Sequence Classification
inferredcites →https://doi.org/10.1016/j.ajhg.2013.06.020openalex-snapshot
RFMix: A Discriminative Modeling Approach for Rapid and Robust Local-Ancestry Inference
inferredcites →https://doi.org/10.1017/cbo9780511801389openalex-snapshot
An Introduction to Support Vector Machines and Other Kernel-based Learning Methods
inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot
An integrated map of genetic variation from 1,092 human genomes
inferredcites →https://doi.org/10.1038/nrg2813openalex-snapshot
New approaches to population stratification in genome-wide association studies
inferredcites →https://doi.org/10.1038/nrg3002openalex-snapshot
New approaches to disease mapping in admixed populations
inferredcites →https://doi.org/10.1086/504302openalex-snapshot
Reconstructing Genetic Ancestry Blocks in Admixed Individuals
inferredcites →https://doi.org/10.1093/bioinformatics/btp197openalex-snapshot
Inference of locus-specific ancestry in closely related populations
inferredcites →https://doi.org/10.1093/genetics/164.4.1567openalex-snapshot
Inference of Population Structure Using Multilocus Genotype Data: Linked Loci and Correlated Allele Frequencies
inferredcites →https://doi.org/10.1111/j.2517-6161.1977.tb01600.xopenalex-snapshot
Maximum Likelihood from Incomplete Data Via the EM Algorithm
inferredcites →https://doi.org/10.1126/science.1243518openalex-snapshot
A Genetic Atlas of Human Admixture History
inferredcites →https://doi.org/10.1145/1102351.1102430openalex-snapshot
Predicting good probabilities with supervised learning
inferredcites →https://doi.org/10.1145/130385.130401openalex-snapshot
A training algorithm for optimal margin classifiers
inferredcites →https://doi.org/10.1145/775047.775151openalex-snapshot
Transforming classifier scores into accurate multiclass probability estimates
inferredcites →https://doi.org/10.1145/775107.775151openalex-snapshot
Transforming classifier scores into accurate multiclass probability estimates
inferredcites →https://doi.org/10.1146/annurev-genom-090810-183123openalex-snapshot
Perspectives on Human Population Structure at the Cusp of the Sequencing Era
inferredcites →https://doi.org/10.1186/1471-2105-7-s1-s9openalex-snapshot
Learning Interpretable SVMs for Biological Sequence Classification
inferredcites →https://doi.org/10.1186/1471-2156-13-49openalex-snapshot
Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations
inferredcites →https://doi.org/10.1371/journal.pgen.0020143openalex-snapshot
European Population Substructure: Clustering of Northern and Southern Populations
inferredcites →https://doi.org/10.1371/journal.pgen.0030236openalex-snapshot
Discerning the Ancestry of European Americans in Genetic Association Studies
inferredcites →https://doi.org/10.1371/journal.pgen.1000519openalex-snapshot
Sensitive Detection of Chromosomal Segments of Distinct Ancestry in Admixed Populations
inferredcites →https://doi.org/10.1371/journal.pone.0005472openalex-snapshot
Genetic Structure of Europeans: A View from the North–East
inferredcites →https://doi.org/10.1371/journal.pone.0034267openalex-snapshot
Cryptic Distant Relatives Are Common in Both Isolated and Cosmopolitan Genetic Samples
inferredcites →https://doi.org/10.1371/journal.pone.0097282openalex-snapshot
HLA Diversity in the 1000 Genomes Dataset
inferredcites →https://doi.org/10.2307/1271368openalex-snapshot
Statistical Learning Theory
inferredcites →https://doi.org/10.2307/2346866openalex-snapshot
Reliability of Subjective Probability Forecasts of Precipitation and Temperature
inferredcites →https://doi.org/10.7551/mitpress/8996.003.0005openalex-snapshot
Interior-Point Methods for Large-Scale Cone Programming

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Genetic prediction of impulse control disorders in Parkinson's disease
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Gene–Environment Interactions for Parkinson's Disease
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The Genetic Ancestry of African Americans, Latinos, and European Americans across the United States
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Multiethnic GWAS Reveals Polygenic Architecture of Earlobe Attachment
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Characterization of Prevalence and Health Consequences of Uniparental Disomy in Four Million Individuals from the General Population
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Genetic Consequences of the Transatlantic Slave Trade in the Americas
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Challenges of accurately estimating sex-biased admixture from X chromosomal and autosomal ancestry proportions
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Response to Pfenning and Lachance
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Reliability of Ancestry-specific Prostate Cancer Genetic Risk Score in Four Racial and Ethnic Populations
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Age-induced and photoinduced changes in gene expression profiles in facial skin of Caucasian females across 6 decades of age
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Viewing direct-to-consumer genetic test results for depression risk is psychologically well tolerated: Evidence from a longitudinal equivalence study
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Identification of 15 genetic loci associated with risk of major depression in individuals of European descent
inferred← citeshttps://doi.org/10.1038/ng.3954openalex-snapshot
Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
inferred← citeshttps://doi.org/10.1038/ng.3955openalex-snapshot
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
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Genome-wide association study of problematic opioid prescription use in 132,113 23andMe research participants of European ancestry
inferred← citeshttps://doi.org/10.1038/s41380-025-03219-2openalex-snapshot
Genome-wide association studies of lifetime and frequency of cannabis use in 131,895 individuals
inferred← citeshttps://doi.org/10.1038/s41380-026-03712-2openalex-snapshot
Molecular genetic influences on sustained attention and executive processes and their links with psychopathology in the AFFECT study
inferred← citeshttps://doi.org/10.1038/s41386-024-01870-xopenalex-snapshot
Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations
inferred← citeshttps://doi.org/10.1038/s41397-026-00424-2openalex-snapshot
Large-scale analysis demonstrates the influence of CYP2C19 genotype on specific SSRI side effects
inferred← citeshttps://doi.org/10.1038/s41398-022-01877-2openalex-snapshot
Characterizing mood disorders in the AFFECT study: a large, longitudinal, and phenotypically rich genetic cohort in the US
inferred← citeshttps://doi.org/10.1038/s41398-023-02453-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41467-017-00257-5openalex-snapshot
Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
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Localization of adaptive variants in human genomes using averaged one-dependence estimation
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Disease risk scores for skin cancers
inferred← citeshttps://doi.org/10.1038/s41467-020-20585-3openalex-snapshot
Genetic determinants of daytime napping and effects on cardiometabolic health
inferred← citeshttps://doi.org/10.1038/s41467-021-23873-8openalex-snapshot
A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects
inferred← citeshttps://doi.org/10.1038/s41467-021-25171-9openalex-snapshot
Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets
inferred← citeshttps://doi.org/10.1038/s41467-022-30765-yopenalex-snapshot
Genome-wide association analysis and replication in 810,625 individuals with varicose veins
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Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects
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The Parkinson’s phenome—traits associated with Parkinson’s disease in a broadly phenotyped cohort
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Analysis of rare Parkinson’s disease variants in millions of people
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Bidirectional relationship between olfaction and Parkinson’s disease
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Genome-wide association study of REM sleep behavior disorder in Parkinson’s disease
inferred← citeshttps://doi.org/10.1038/s41562-020-00956-yopenalex-snapshot
Genome-wide association study identifies 48 common genetic variants associated with handedness
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Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity
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The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste
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Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
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Large-scale genome-wide analyses of stuttering
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Genome-wide association study of delay discounting in 23,217 adult research participants of European ancestry
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Identifying Ashkenazi Jewish BRCA1/2 founder variants in individuals who do not self-report Jewish ancestry
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Correlations in sleeping patterns and circadian preference between spouses
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Prioritizing privacy and presentation of supportable hypothesis testing in forensic genetic genealogy investigations
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A comprehensive survey of models for dissecting local ancestry deconvolution in human genome
inferred← citeshttps://doi.org/10.1093/bioinformatics/btae616openalex-snapshot
AncestryGrapher toolkit: Python command-line pipelines to visualize global- and local- ancestry inferences from the RFMIX version 2 software
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Genetic analysis and natural history of Parkinson’s disease due to the LRRK2 G2019S variant
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Combined analysis of keratinocyte cancers identifies novel genome-wide loci
inferred← citeshttps://doi.org/10.1093/hmg/ddz219openalex-snapshot
Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness
inferred← citeshttps://doi.org/10.1101/076133openalex-snapshot
Correcting subtle stratification in summary association statistics
inferred← citeshttps://doi.org/10.1101/2020.04.21.053876openalex-snapshot
XGMix: Local-Ancestry Inference with Stacked XGBoost
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Genome-wide association analysis and replication in 810,625 individuals identifies novel therapeutic targets for varicose veins
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Genome-wide meta-analysis of insomnia in over 2.3 million individuals implicates involvement of specific biological pathways through gene-prioritization
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A scalable pipeline for local ancestry inference using tens of thousands of reference haplotypes
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Large-scale trans-ethnic replication and discovery of genetic associations for rare diseases with self-reported medical data
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High Resolution Ancestry Deconvolution for Next Generation Genomic Data
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CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice
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Genome-wide Association Identifies Novel Etiological Insights Associated with Parkinson’s Disease in African and African Admixed Populations
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SNVstory: A dockerized algorithm for rapid and accurate inference of sub-continental ancestry
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Genome-Wide Association Studies of Coffee Intake in UK/US Participants of European Ancestry Uncover Gene-Cohort Influences
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AncestryGrapher toolkit: Python command-line pipelines to visualize global– and local– ancestry inferences from the RFMix2 software
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The Metabolic Role of MAP3K15: Genetic and Phenotypic Insights from the 23andMe Research Database and Genetics-Driven Recruitment
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Trans-ancestral Genome Wide Association Study of Sporadic and Recurrent Miscarriage
inferred← citeshttps://doi.org/10.1101/2024.04.03.24305274openalex-snapshot
Multi-ancestry GWAS of diarrhea during acute SARS-CoV2 infection identifies multiple novel loci and contrasting etiological roles of irritable bowel syndrome subtypes
inferred← citeshttps://doi.org/10.1101/2024.06.14.24308946openalex-snapshot
Genome-wide association studies of lifetime and frequency cannabis use in 131,895 individuals
inferred← citeshttps://doi.org/10.1101/2024.06.17.24309059openalex-snapshot
The impact on clinical success from the 23andMe cohort
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Multi-ancestry GWAS of Long COVID identifies immune-related loci and etiological links to chronic fatigue syndrome, fibromyalgia and depression
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Monogenic Parkinson’s Disease and the Impact of APOE E4: A Case-Control Study
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The genetic architecture of gene expression in individuals of African and European ancestry
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Molecular genetic influences on attentional control and other executive processes and their links with psychopathology in the AFFECT study
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Bayesian inference of population structure using identity-by-descent-based stochastic block models
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The Parkinson’s Phenome: Traits Associated with Parkinson’s Disease in a Large and Deeply Phenotyped Cohort
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LDpred-funct: incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets
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SMIA: a simple way for inference of admixed population ancestors
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Unsupervised detection of ancestry tracks with the GHap r package
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Genome‐wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry
inferred← citeshttps://doi.org/10.1111/age.13164openalex-snapshot
Bos taurus haplotypes segregating in Nellore (Bos indicus) cattle
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A Modelling Strategy to Estimate Conditional Probabilities of African Origins: The Collapse of the Oyo Empire and The Transatlantic Slave Trade, 1817–1836
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Nuclear genome-wide associations with mitochondrial heteroplasmy
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Germline EGFR T790M mutation and lung cancer risk
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Quantifying prion disease penetrance using large population control cohorts
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Análise da ancestralidades genética da população de São Paulo
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Ancestry-independent risk of venous thromboembolism in individuals with sickle cell trait vs factor V Leiden
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SNVstory: inferring genetic ancestry from genome sequencing data
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Adjusting for principal components can induce collider bias in genome-wide association studies
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The association of clinical phenotypes to known AD/FTD genetic risk loci and their inter-relationship
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Genome-wide association studies of impulsive personality traits (BIS-11 and UPPSP) and drug experimentation in up to 22,861 adult research participants identify loci in the CACNA1I and CADM2 genes
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A Genealogical Look at Shared Ancestry on the X Chromosome
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Exploring your Inner Hades: DNA as Mortuary Archaeology
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Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study
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De la movilidad humana a la integración social: Tijuana como espacio de encuentro y tensión migratoria
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In Search of the jüdische Typus: A Proposed Benchmark to Test the Genetic Basis of Jewishness Challenges Notions of “Jewish Biomarkers”
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Estimation of Genomic Breed Composition for Purebred and Crossbred Animals Using Sparsely Regularized Admixture Models
inferred← citeshttps://doi.org/10.3389/fnins.2022.971752openalex-snapshot
A genome-wide association study of a rage-related misophonia symptom and the genetic link with audiological traits, psychiatric disorders, and personality
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Class-Conditional VAE-GAN for Local-Ancestry Simulation
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Addressing Ancestry Disparities in Genomic Medicine: A Geographic-aware Algorithm
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Estimating conditional probabilities of historical migrations in the transatlantic slave trade using kriging and Markov decision process models
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Eugenics, Admixture, and Multiculturalism in Twentieth-Century Northern Sweden: Contesting Disability and Sámi Genocide
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Genomic Ancestry Inference of Admixed Population by Identifying Approximate Boundaries of Ancestry Change
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Point cloud local ancestry inference (PCLAI): continuous coordinate-based ancestry along the genome
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Age-Related Speech-in-Noise Hearing Loss in Parkinson’s Disease and APOE E4 Carriers
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