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Engineering Cell Fate: The Roles of iPSC Transcription Factors, Chemicals, Barriers and Enhancing Factors in Reprogramming and Transdifferentiation

https://doi.org/10.1101/019455

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Optimal reprogramming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells

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Direct Conversion of Mouse Fibroblasts to Hepatocyte–Like Cells Using Forced Expression of Endodermal Transcription Factors

inferredcites →https://doi.org/10.1002/stem.1054openalex-snapshot

Context‐Dependent Enhancement of Induced Pluripotent Stem Cell Reprogramming by Silencing Puma

inferredcites →https://doi.org/10.1002/stem.1091openalex-snapshot

Neural Stem Cells Directly Differentiated from Partially Reprogrammed Fibroblasts Rapidly Acquire Gliogenic Competency

inferredcites →https://doi.org/10.1002/stem.1293openalex-snapshot

An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells

inferredcites →https://doi.org/10.1002/stem.1374openalex-snapshot

NuRD Blocks Reprogramming of Mouse Somatic Cells into Pluripotent Stem Cells

inferredcites →https://doi.org/10.1002/stem.1721openalex-snapshot

Molecular Evidence for OCT4-Induced Plasticity in Adult Human Fibroblasts Required for Direct Cell Fate Conversion to Lineage Specific Progenitors

inferredcites →https://doi.org/10.1002/stem.402openalex-snapshot

Butyrate Greatly Enhances Derivation of Human Induced Pluripotent Stem Cells by Promoting Epigenetic Remodeling and the Expression of Pluripotency-Associated Genes

inferredcites →https://doi.org/10.1002/stem.491openalex-snapshot

Loss of Bright/ARID3a Function Promotes Developmental Plasticity

inferredcites →https://doi.org/10.1002/stem.768openalex-snapshot

Concise Review: A Chemical Approach to Control Cell Fate and Function

inferredcites →https://doi.org/10.1007/s12015-009-9094-9openalex-snapshot

Embryonic Stem Cell Marker Expression Pattern in Human Mesenchymal Stem Cells Derived from Bone Marrow, Adipose Tissue, Heart and Dermis

inferredcites →https://doi.org/10.1007/s13238-012-2922-8openalex-snapshot

The genomic stability of induced pluripotent stem cells

inferredcites →https://doi.org/10.1007/s13238-013-0015-yopenalex-snapshot

Direct reprogramming of porcine fibroblasts to neural progenitor cells

inferredcites →https://doi.org/10.1016/0092-8674(87)90585-xopenalex-snapshot

Expression of a single transfected cDNA converts fibroblasts to myoblasts

inferredcites →https://doi.org/10.1016/j.biomaterials.2013.05.050openalex-snapshot

Direct reprogramming of mouse fibroblasts to cardiomyocyte-like cells using Yamanaka factors on engineered poly(ethylene glycol) (PEG) hydrogels

inferredcites →https://doi.org/10.1016/j.cell.2005.02.018openalex-snapshot

Ectopic Expression of Oct-4 Blocks Progenitor-Cell Differentiation and Causes Dysplasia in Epithelial Tissues

inferredcites →https://doi.org/10.1016/j.cell.2006.07.024openalex-snapshot

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

inferredcites →https://doi.org/10.1016/j.cell.2007.11.019openalex-snapshot

Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors

inferredcites →https://doi.org/10.1016/j.cell.2008.03.028openalex-snapshot

Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency

inferredcites →https://doi.org/10.1016/j.cell.2009.01.001openalex-snapshot

Role of the Murine Reprogramming Factors in the Induction of Pluripotency

inferredcites →https://doi.org/10.1016/j.cell.2009.01.023openalex-snapshot

Oct4-Induced Pluripotency in Adult Neural Stem Cells

inferredcites →https://doi.org/10.1016/j.cell.2009.02.013openalex-snapshot

Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors

inferredcites →https://doi.org/10.1016/j.cell.2010.07.002openalex-snapshot

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

inferredcites →https://doi.org/10.1016/j.cell.2011.05.019openalex-snapshot

Chromatin Connections to Pluripotency and Cellular Reprogramming

inferredcites →https://doi.org/10.1016/j.cell.2012.09.034openalex-snapshot

Activation of Innate Immunity Is Required for Efficient Nuclear Reprogramming

inferredcites →https://doi.org/10.1016/j.cell.2012.11.039openalex-snapshot

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

inferredcites →https://doi.org/10.1016/j.cell.2012.11.045openalex-snapshot

Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits

inferredcites →https://doi.org/10.1016/j.cell.2013.05.001openalex-snapshot

Induction of Pluripotency in Mouse Somatic Cells with Lineage Specifiers

inferredcites →https://doi.org/10.1016/j.cell.2014.01.005openalex-snapshot

Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation

inferredcites →https://doi.org/10.1016/j.cell.2014.01.020openalex-snapshot

Nonstochastic Reprogramming from a Privileged Somatic Cell State

inferredcites →https://doi.org/10.1016/j.cell.2014.04.006openalex-snapshot

Reprogramming Committed Murine Blood Cells to Induced Hematopoietic Stem Cells with Defined Factors

inferredcites →https://doi.org/10.1016/j.cell.2014.05.040openalex-snapshot

Systematic Identification of Barriers to Human iPSC Generation

inferredcites →https://doi.org/10.1016/j.cell.2014.07.020openalex-snapshot

CellNet: Network Biology Applied to Stem Cell Engineering

inferredcites →https://doi.org/10.1016/j.cell.2014.07.021openalex-snapshot

Dissecting Engineered Cell Types and Enhancing Cell Fate Conversion via CellNet

inferredcites →https://doi.org/10.1016/j.cell.2014.08.029openalex-snapshot

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

inferredcites →https://doi.org/10.1016/j.celrep.2013.04.004openalex-snapshot

Generation of Integration-free and Region-Specific Neural Progenitors from Primate Fibroblasts

inferredcites →https://doi.org/10.1016/j.celrep.2013.05.015openalex-snapshot

Stage-Specific Regulation of Reprogramming to Induced Pluripotent Stem Cells by Wnt Signaling and T Cell Factor Proteins

inferredcites →https://doi.org/10.1016/j.celrep.2014.01.038openalex-snapshot

Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4

inferredcites →https://doi.org/10.1016/j.celrep.2014.07.002openalex-snapshot

Genome-wide Functional Analysis Reveals Factors Needed at the Transition Steps of Induced Reprogramming

inferredcites →https://doi.org/10.1016/j.celrep.2014.11.002openalex-snapshot

Direct Reprogramming of Murine Fibroblasts to Hematopoietic Progenitor Cells

inferredcites →https://doi.org/10.1016/j.celrep.2014.12.038openalex-snapshot

Rapid and Efficient Direct Conversion of Human Adult Somatic Cells into Neural Stem Cells by HMGA2/let-7b

inferredcites →https://doi.org/10.1016/j.cub.2009.08.025openalex-snapshot

Tgfβ Signal Inhibition Cooperates in the Induction of iPSCs and Replaces Sox2 and cMyc

inferredcites →https://doi.org/10.1016/j.cub.2010.11.074openalex-snapshot

Nanog Overcomes Reprogramming Barriers and Induces Pluripotency in Minimal Conditions

inferredcites →https://doi.org/10.1016/j.devcel.2009.01.012openalex-snapshot

Neurogenin3 Is Sufficient for Transdetermination of Hepatic Progenitor Cells into Neo-Islets In Vivo but Not Transdifferentiation of Hepatocytes

inferredcites →https://doi.org/10.1016/j.gde.2014.08.003openalex-snapshot

The extended pluripotency protein interactome and its links to reprogramming

inferredcites →https://doi.org/10.1016/j.gde.2014.09.006openalex-snapshot

Chemical approaches to cell reprogramming

inferredcites →https://doi.org/10.1016/j.gde.2014.09.009openalex-snapshot

Reprogramming by lineage specifiers: blurring the lines between pluripotency and differentiation

inferredcites →https://doi.org/10.1016/j.gpb.2013.09.002openalex-snapshot

Clinical Therapy Using iPSCs: Hopes and Challenges

inferredcites →https://doi.org/10.1016/j.gpb.2013.09.008openalex-snapshot

Integration-Free Methods for Generating Induced Pluripotent Stem Cells

inferredcites →https://doi.org/10.1016/j.molcel.2012.09.008openalex-snapshot

Molecular Roadblocks for Cellular Reprogramming

inferredcites →https://doi.org/10.1016/j.scr.2013.02.005openalex-snapshot

Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming

inferredcites →https://doi.org/10.1016/j.scr.2013.09.007openalex-snapshot

Direct lineage reprogramming of mouse fibroblasts to functional midbrain dopaminergic neuronal progenitors

inferredcites →https://doi.org/10.1016/j.stem.2007.05.012openalex-snapshot

Strategies and New Developments in the Generation of Patient-Specific Pluripotent Stem Cells

inferredcites →https://doi.org/10.1016/j.stem.2008.08.017openalex-snapshot

Periodic Activation of Wnt/β-Catenin Signaling Enhances Somatic Cell Reprogramming Mediated by Cell Fusion

inferredcites →https://doi.org/10.1016/j.stem.2008.10.002openalex-snapshot

Two Supporting Factors Greatly Improve the Efficiency of Human iPSC Generation

inferredcites →https://doi.org/10.1016/j.stem.2008.10.004openalex-snapshot

Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds

inferredcites →https://doi.org/10.1016/j.stem.2009.04.005openalex-snapshot

Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins

inferredcites →https://doi.org/10.1016/j.stem.2009.05.005openalex-snapshot

Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins

inferredcites →https://doi.org/10.1016/j.stem.2009.09.008openalex-snapshot

Generation of Induced Pluripotent Stem Cells from Human Cord Blood Using OCT4 and SOX2

inferredcites →https://doi.org/10.1016/j.stem.2009.09.012openalex-snapshot

A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

inferredcites →https://doi.org/10.1016/j.stem.2009.10.004openalex-snapshot

A Robust and Highly Efficient Immune Cell Reprogramming System

inferredcites →https://doi.org/10.1016/j.stem.2009.12.001openalex-snapshot

Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells

inferredcites →https://doi.org/10.1016/j.stem.2010.04.014openalex-snapshot

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

inferredcites →https://doi.org/10.1016/j.stem.2010.04.015openalex-snapshot

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

inferredcites →https://doi.org/10.1016/j.stem.2010.08.012openalex-snapshot

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

inferredcites →https://doi.org/10.1016/j.stem.2010.11.015openalex-snapshot

Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds

inferredcites →https://doi.org/10.1016/j.stem.2011.03.001openalex-snapshot

Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency

inferredcites →https://doi.org/10.1016/j.stem.2011.03.013openalex-snapshot

A Precarious Balance: Pluripotency Factors as Lineage Specifiers

inferredcites →https://doi.org/10.1016/j.stem.2011.10.005openalex-snapshot

The Histone Demethylases Jhdm1a/1b Enhance Somatic Cell Reprogramming in a Vitamin-C-Dependent Manner

inferredcites →https://doi.org/10.1016/j.stem.2011.11.003openalex-snapshot

Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells

inferredcites →https://doi.org/10.1016/j.stem.2012.02.021openalex-snapshot

Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors

inferredcites →https://doi.org/10.1016/j.stem.2012.03.003openalex-snapshot

Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells

inferredcites →https://doi.org/10.1016/j.stem.2012.05.018openalex-snapshot

Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor

inferredcites →https://doi.org/10.1016/j.stem.2012.09.011openalex-snapshot

Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System

inferredcites →https://doi.org/10.1016/j.stem.2013.05.024openalex-snapshot

Induction of a Hemogenic Program in Mouse Fibroblasts

inferredcites →https://doi.org/10.1016/j.stem.2013.06.017openalex-snapshot

Reprogramming Fibroblasts into Bipotential Hepatic Stem Cells by Defined Factors

inferredcites →https://doi.org/10.1016/j.stem.2013.06.019openalex-snapshot

Reprogramming of Human Fibroblasts to Pluripotency with Lineage Specifiers

inferredcites →https://doi.org/10.1016/j.stem.2013.08.002openalex-snapshot

Chemical Approaches to Stem Cell Biology and Therapeutics

inferredcites →https://doi.org/10.1016/j.stem.2013.11.001openalex-snapshot

The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes

inferredcites →https://doi.org/10.1016/j.stem.2013.12.015openalex-snapshot

Histone Variants Enriched in Oocytes Enhance Reprogramming to Induced Pluripotent Stem Cells

inferredcites →https://doi.org/10.1016/j.stem.2014.01.003openalex-snapshot

Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes

inferredcites →https://doi.org/10.1016/j.stem.2014.01.006openalex-snapshot

Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages

inferredcites →https://doi.org/10.1016/j.stem.2014.01.008openalex-snapshot

Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming

inferredcites →https://doi.org/10.1016/j.stem.2014.02.013openalex-snapshot

INO80 Facilitates Pluripotency Gene Activation in Embryonic Stem Cell Self-Renewal, Reprogramming, and Blastocyst Development

inferredcites →https://doi.org/10.1016/j.stem.2014.03.001openalex-snapshot

Kinome-wide Functional Analysis Highlights the Role of Cytoskeletal Remodeling in Somatic Cell Reprogramming

inferredcites →https://doi.org/10.1016/j.stem.2014.04.019openalex-snapshot

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner

inferredcites →https://doi.org/10.1016/j.stem.2014.05.002openalex-snapshot

Molecular Control of Induced Pluripotency

inferredcites →https://doi.org/10.1016/j.stem.2014.05.006openalex-snapshot

Chromatin Repressive Complexes in Stem Cells, Development, and Cancer

inferredcites →https://doi.org/10.1016/j.stem.2014.07.002openalex-snapshot

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

inferredcites →https://doi.org/10.1016/j.stem.2014.10.018openalex-snapshot

Virtual Karyotyping Reveals Greater Chromosomal Stability in Neural Cells Derived by Transdifferentiation than Those from Stem Cells

inferredcites →https://doi.org/10.1016/j.stem.2014.12.013openalex-snapshot

Generating iPSCs: Translating Cell Reprogramming Science into Scalable and Robust Biomanufacturing Strategies

inferredcites →https://doi.org/10.1016/j.stem.2015.01.013openalex-snapshot

Direct Lineage Reprogramming: Strategies, Mechanisms, and Applications

inferredcites →https://doi.org/10.1016/j.stem.2018.07.004openalex-snapshot

Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency

inferredcites →https://doi.org/10.1016/j.stemcr.2013.07.005openalex-snapshot

Direct Reprogramming of Human Fibroblasts toward a Cardiomyocyte-like State

inferredcites →https://doi.org/10.1016/j.stemcr.2013.11.006openalex-snapshot

Induced Pluripotent Stem Cell Generation-Associated Point Mutations Arise during the Initial Stages of the Conversion of These Cells

inferredcites →https://doi.org/10.1016/j.stemcr.2013.12.002openalex-snapshot

Bright/Arid3A Acts as a Barrier to Somatic Cell Reprogramming through Direct Regulation of Oct4, Sox2, and Nanog

inferredcites →https://doi.org/10.1016/j.stemcr.2014.01.014openalex-snapshot

Platform for Induction and Maintenance of Transgene-free hiPSCs Resembling Ground State Pluripotent Stem Cells

inferredcites →https://doi.org/10.1016/j.stemcr.2014.04.001openalex-snapshot

Temporal Perturbation of the Wnt Signaling Pathway in the Control of Cell Reprogramming Is Modulated by TCF1

inferredcites →https://doi.org/10.1016/j.stemcr.2014.07.006openalex-snapshot

Transient p53 Suppression Increases Reprogramming of Human Fibroblasts without Affecting Apoptosis and DNA Damage

inferredcites →https://doi.org/10.1016/j.stemcr.2014.08.003openalex-snapshot

Combinatorial Modulation of Signaling Pathways Reveals Cell-Type-Specific Requirements for Highly Efficient and Synchronous iPSC Reprogramming

inferredcites →https://doi.org/10.1016/j.stemcr.2014.09.008openalex-snapshot

The Epithelial-Mesenchymal Transition Factor SNAIL Paradoxically Enhances Reprogramming

inferredcites →https://doi.org/10.1016/j.stemcr.2014.12.003openalex-snapshot

Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin

inferredcites →https://doi.org/10.1016/j.tcb.2009.12.004openalex-snapshot

p53 and stem cells: new developments and new concerns

inferredcites →https://doi.org/10.1016/s0092-8674(00)00171-9openalex-snapshot

p53

inferredcites →https://doi.org/10.1016/s0092-8674(04)00208-9openalex-snapshot

Plasticity of Adult Stem Cells

inferredcites →https://doi.org/10.1016/s0092-8674(04)00419-2openalex-snapshot

Stepwise Reprogramming of B Cells into Macrophages

inferredcites →https://doi.org/10.1038/35046522openalex-snapshot

Molecular basis of transdifferentiation of pancreas to liver

inferredcites →https://doi.org/10.1038/385810a0openalex-snapshot

Viable offspring derived from fetal and adult mammalian cells

inferredcites →https://doi.org/10.1038/cdd.2012.125openalex-snapshot

p53 Counteracts reprogramming by inhibiting mesenchymal-to-epithelial transition

inferredcites →https://doi.org/10.1038/cmi.2013.62openalex-snapshot

Induced pluripotent stem cell (iPSCs) and their application in immunotherapy

inferredcites →https://doi.org/10.1038/cr.2010.142openalex-snapshot

Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules

inferredcites →https://doi.org/10.1038/cr.2011.12openalex-snapshot

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures

inferredcites →https://doi.org/10.1038/cr.2011.51openalex-snapshot

Rational optimization of reprogramming culture conditions for the generation of induced pluripotent stem cells with ultra-high efficiency and fast kinetics

inferredcites →https://doi.org/10.1038/cr.2012.182openalex-snapshot

Chemical approaches to studying stem cell biology

inferredcites →https://doi.org/10.1038/cr.2013.1openalex-snapshot

A blueprint for engineering cell fate: current technologies to reprogram cell identity

inferredcites →https://doi.org/10.1038/cr.2013.156openalex-snapshot

Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells

inferredcites →https://doi.org/10.1038/mt.2009.93openalex-snapshot

Transdetermination: A New Trend in Cellular Reprogramming

inferredcites →https://doi.org/10.1038/nature.2014.15915openalex-snapshot

Japanese woman is first recipient of next-generation stem cells

inferredcites →https://doi.org/10.1038/nature05934openalex-snapshot

Generation of germline-competent induced pluripotent stem cells

inferredcites →https://doi.org/10.1038/nature05944openalex-snapshot

In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state

inferredcites →https://doi.org/10.1038/nature06968openalex-snapshot

The ground state of embryonic stem cell self-renewal

inferredcites →https://doi.org/10.1038/nature07056openalex-snapshot

Dissecting direct reprogramming through integrative genomic analysis

inferredcites →https://doi.org/10.1038/nature07863openalex-snapshot

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

inferredcites →https://doi.org/10.1038/nature07864openalex-snapshot

Virus-free induction of pluripotency and subsequent excision of reprogramming factors

inferredcites →https://doi.org/10.1038/nature08235openalex-snapshot

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

inferredcites →https://doi.org/10.1038/nature08285openalex-snapshot

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

inferredcites →https://doi.org/10.1038/nature08287openalex-snapshot

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

inferredcites →https://doi.org/10.1038/nature08290openalex-snapshot

The Ink4/Arf locus is a barrier for iPS cell reprogramming

inferredcites →https://doi.org/10.1038/nature08311openalex-snapshot

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

inferredcites →https://doi.org/10.1038/nature08436openalex-snapshot

Direct reprogramming of human neural stem cells by OCT4

inferredcites →https://doi.org/10.1038/nature08592openalex-snapshot

Direct cell reprogramming is a stochastic process amenable to acceleration

inferredcites →https://doi.org/10.1038/nature08797openalex-snapshot

Direct conversion of fibroblasts to functional neurons by defined factors

inferredcites →https://doi.org/10.1038/nature09591openalex-snapshot

Direct conversion of human fibroblasts to multilineage blood progenitors

inferredcites →https://doi.org/10.1038/nature10106openalex-snapshot

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

inferredcites →https://doi.org/10.1038/nature10116openalex-snapshot

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors

inferredcites →https://doi.org/10.1038/nature10263openalex-snapshot

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors

inferredcites →https://doi.org/10.1038/nature10953openalex-snapshot

Chromatin-modifying enzymes as modulators of reprogramming

inferredcites →https://doi.org/10.1038/nature11044openalex-snapshot

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

inferredcites →https://doi.org/10.1038/nature11468openalex-snapshot

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

inferredcites →https://doi.org/10.1038/nature12587openalex-snapshot

Deterministic direct reprogramming of somatic cells to pluripotency

inferredcites →https://doi.org/10.1038/nature12885openalex-snapshot

C/EBPα poises B cells for rapid reprogramming into induced pluripotent stem cells

inferredcites →https://doi.org/10.1038/nature13020openalex-snapshot

Mouse liver repopulation with hepatocytes generated from human fibroblasts

inferredcites →https://doi.org/10.1038/nature13547openalex-snapshot

Reprogramming human endothelial cells to haematopoietic cells requires vascular induction

inferredcites →https://doi.org/10.1038/nature13551openalex-snapshot

Abnormalities in human pluripotent cells due to reprogramming mechanisms

inferredcites →https://doi.org/10.1038/nature14274openalex-snapshot

Early reprogramming regulators identified by prospective isolation and mass cytometry

inferredcites →https://doi.org/10.1038/nbt.1502openalex-snapshot

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2

inferredcites →https://doi.org/10.1038/nbt.1667openalex-snapshot

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

inferredcites →https://doi.org/10.1038/nbt.1862openalex-snapshot

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

inferredcites →https://doi.org/10.1038/nbt.2465openalex-snapshot

Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18

inferredcites →https://doi.org/10.1038/nbt.2561openalex-snapshot

Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

inferredcites →https://doi.org/10.1038/nbt.2564openalex-snapshot

Generation of oligodendroglial cells by direct lineage conversion

inferredcites →https://doi.org/10.1038/nbt.3270openalex-snapshot

Transient acquisition of pluripotency during somatic cell transdifferentiation with iPSC reprogramming factors

inferredcites →https://doi.org/10.1038/nbt1483openalex-snapshot

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

inferredcites →https://doi.org/10.1038/ncb2136openalex-snapshot

Direct reprogramming of fibroblasts into epiblast stem cells

inferredcites →https://doi.org/10.1038/ncb2164openalex-snapshot

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

inferredcites →https://doi.org/10.1038/ncb2567openalex-snapshot

Lineage conversion methodologies meet the reprogramming toolbox

inferredcites →https://doi.org/10.1038/ncomms2059openalex-snapshot

A kinase inhibitor screen identifies small-molecule enhancers of reprogramming and iPS cell generation

inferredcites →https://doi.org/10.1038/ncomms2582openalex-snapshot

MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency

inferredcites →https://doi.org/10.1038/ncomms3183openalex-snapshot

Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons

inferredcites →https://doi.org/10.1038/ncomms4678openalex-snapshot

Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm

inferredcites →https://doi.org/10.1038/ng.1110openalex-snapshot

Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all–iPS cell mice from terminally differentiated B cells

inferredcites →https://doi.org/10.1038/ng.2491openalex-snapshot

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

inferredcites →https://doi.org/10.1038/ng.375openalex-snapshot

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

inferredcites →https://doi.org/10.1038/ng.428openalex-snapshot

Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells

inferredcites →https://doi.org/10.1038/nmat3765openalex-snapshot

Delivery materials for siRNA therapeutics

inferredcites →https://doi.org/10.1038/nmeth.1393openalex-snapshot

A chemical platform for improved induction of human iPSCs

inferredcites →https://doi.org/10.1038/nmeth.1591openalex-snapshot

A more efficient method to generate integration-free human iPS cells

inferredcites →https://doi.org/10.1038/nmeth.2255openalex-snapshot

Conversion of human fibroblasts to angioblast-like progenitor cells

inferredcites →https://doi.org/10.1038/nmeth.2283openalex-snapshot

Generation of integration-free neural progenitor cells from cells in human urine

inferredcites →https://doi.org/10.1038/nn828openalex-snapshot

Glial cells generate neurons: the role of the transcription factor Pax6

inferredcites →https://doi.org/10.1038/nnano.2014.84openalex-snapshot

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

inferredcites →https://doi.org/10.1038/nprot.2012.150openalex-snapshot

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

inferredcites →https://doi.org/10.1038/nrd4161openalex-snapshot

The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment

inferredcites →https://doi.org/10.1038/nrg2937openalex-snapshot

Methods for making induced pluripotent stem cells: reprogramming à la carte

inferredcites →https://doi.org/10.1038/nrg2955openalex-snapshot

Progress in understanding reprogramming to the induced pluripotent state

inferredcites →https://doi.org/10.1038/nrg3473openalex-snapshot

Mechanisms and models of somatic cell reprogramming

inferredcites →https://doi.org/10.1038/nrm3043openalex-snapshot

Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration

inferredcites →https://doi.org/10.1038/nrm3584openalex-snapshot

Origins and implications of pluripotent stem cell variability and heterogeneity

inferredcites →https://doi.org/10.1038/nrm3758openalex-snapshot

Molecular mechanisms of epithelial–mesenchymal transition

inferredcites →https://doi.org/10.1038/nsmb.1499openalex-snapshot

The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b

inferredcites →https://doi.org/10.1038/sj.onc.1208307openalex-snapshot

Induction of KLF4 in basal keratinocytes blocks the proliferation–differentiation switch and initiates squamous epithelial dysplasia

inferredcites →https://doi.org/10.1038/srep00544openalex-snapshot

A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts

inferredcites →https://doi.org/10.1038/srep05228openalex-snapshot

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes

inferredcites →https://doi.org/10.1055/s-0032-1331802openalex-snapshot

Dedifferentiation, Transdifferentiation, and Reprogramming: Future Directions in Regenerative Medicine

inferredcites →https://doi.org/10.1073/pnas.0813139106openalex-snapshot

Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a / Arf locus

inferredcites →https://doi.org/10.1073/pnas.0904825106openalex-snapshot

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

inferredcites →https://doi.org/10.1073/pnas.1100893108openalex-snapshot

Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1

inferredcites →https://doi.org/10.1073/pnas.1103113108openalex-snapshot

Direct reprogramming of mouse fibroblasts to neural progenitors

inferredcites →https://doi.org/10.1073/pnas.1103509108openalex-snapshot

Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors

inferredcites →https://doi.org/10.1073/pnas.1120299109openalex-snapshot

Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors

inferredcites →https://doi.org/10.1073/pnas.1121003109openalex-snapshot

Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells

inferredcites →https://doi.org/10.1073/pnas.1200250109openalex-snapshot

Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

inferredcites →https://doi.org/10.1073/pnas.1208533109openalex-snapshot

Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming

inferredcites →https://doi.org/10.1073/pnas.1219181110openalex-snapshot

Identification of Oct4-activating compounds that enhance reprogramming efficiency

inferredcites →https://doi.org/10.1073/pnas.1304053110openalex-snapshot

Induction of human cardiomyocyte-like cells from fibroblasts by defined factors

inferredcites →https://doi.org/10.1073/pnas.1319061110openalex-snapshot

Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells

inferredcites →https://doi.org/10.1074/jbc.c111.235960openalex-snapshot

MicroRNA Cluster 302–367 Enhances Somatic Cell Reprogramming by Accelerating a Mesenchymal-to-Epithelial Transition

inferredcites →https://doi.org/10.1074/jbc.m110.142059openalex-snapshot

Butyrate Promotes Induced Pluripotent Stem Cell Generation

inferredcites →https://doi.org/10.1074/jbc.m112.403881openalex-snapshot

Proliferation Rate of Somatic Cells Affects Reprogramming Efficiency

inferredcites →https://doi.org/10.1074/jbc.m113.542845openalex-snapshot

Regulation of Induced Pluripotent Stem (iPS) Cell Induction by Wnt/β-Catenin Signaling

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.tice.2016.07.005openalex-snapshot

Engineering cell fate: Spotlight on cell-activation and signaling-directed lineage conversion

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