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Population diversity jeopardizes the efficacy of antibiotic cycling
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/978-1-4939-0554-6_12openalex-snapshot
Identification of Mutations in Laboratory-Evolved Microbes from Next-Generation Sequencing Data Using breseq
inferredcites →https://doi.org/10.1016/j.tim.2014.11.001openalex-snapshot
Why doesn’t Mycobacterium tuberculosis spread in animals?
inferredcites →https://doi.org/10.1016/j.tim.2015.02.009openalex-snapshot
Collateral sensitivity of antibiotic-resistant microbes
inferredcites →https://doi.org/10.1016/s0140-6736(01)05410-1openalex-snapshot
Linezolid resistance in a clinical isolate of Staphylococcus aureus
inferredcites →https://doi.org/10.1021/pr100918uopenalex-snapshot
Mapping the Protein Interaction Network in Methicillin-Resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1038/msb.2012.76openalex-snapshot
Evolutionary potential, cross‐stress behavior and the genetic basis of acquired stress resistance in Escherichia coli
inferredcites →https://doi.org/10.1038/msb.2013.57openalex-snapshot
Bacterial evolution of antibiotic hypersensitivity
inferredcites →https://doi.org/10.1038/nchembio.2176openalex-snapshot
Compounds that select against the tetracycline-resistance efflux pump
inferredcites →https://doi.org/10.1038/ncomms5352openalex-snapshot
Genome-wide analysis captures the determinants of the antibiotic cross-resistance interaction network
inferredcites →https://doi.org/10.1038/ng.997openalex-snapshot
Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes
inferredcites →https://doi.org/10.1056/nejm200202213460820openalex-snapshot
Emergence of Macrolide Resistance during Treatment of Pneumococcal Pneumonia
inferredcites →https://doi.org/10.1073/pnas.0609839104openalex-snapshot
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing
inferredcites →https://doi.org/10.1073/pnas.1409800111openalex-snapshot
Alternating antibiotic treatments constrain evolutionary paths to multidrug resistance
inferredcites →https://doi.org/10.1086/511642openalex-snapshot
Mutant Selection Window Hypothesis Updated
inferredcites →https://doi.org/10.1093/jac/dkr337openalex-snapshot
Breakthrough bacteraemia due to tigecycline-resistant Escherichia coli with New Delhi metallo- -lactamase (NDM)-1 successfully treated with colistin in a patient with calciphylaxis
inferredcites →https://doi.org/10.1093/jac/dkt418openalex-snapshot
Novel mutations in penicillin-binding protein genes in clinical Staphylococcus aureus isolates that are methicillin resistant on susceptibility testing, but lack the mec gene
inferredcites →https://doi.org/10.1093/molbev/msu191openalex-snapshot
Strength of Selection Pressure Is an Important Parameter Contributing to the Complexity of Antibiotic Resistance Evolution
inferredcites →https://doi.org/10.1093/molbev/msv006openalex-snapshot
Collateral Resistance and Sensitivity Modulate Evolution of High-Level Resistance to Drug Combination Treatment in Staphylococcus aureus
inferredcites →https://doi.org/10.1098/rspb.2007.0640openalex-snapshot
Source–sink dynamics shape the evolution of antibiotic resistance and its pleiotropic fitness cost
inferredcites →https://doi.org/10.1126/science.aad3292openalex-snapshot
Multidrug evolutionary strategies to reverse antibiotic resistance
inferredcites →https://doi.org/10.1126/scitranslmed.3006609openalex-snapshot
Use of Collateral Sensitivity Networks to Design Drug Cycling Protocols That Avoid Resistance Development
inferredcites →https://doi.org/10.1128/aac.05148-11openalex-snapshot
Loss of Function of the GdpP Protein Leads to Joint β-Lactam/Glycopeptide Tolerance in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.40.4.1060openalex-snapshot
GyrB mutations in Staphylococcus aureus strains resistant to cyclothialidine, coumermycin, and novobiocin
inferredcites →https://doi.org/10.1128/aac.41.11.2355openalex-snapshot
Cloning and characterization of the fmt gene which affects the methicillin resistance level and autolysis in the presence of triton X-100 in methicillin-resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.41.2.363openalex-snapshot
The population dynamics of antimicrobial chemotherapy
inferredcites →https://doi.org/10.1128/aac.49.9.3810-3815.2005openalex-snapshot
Accumulation of Mutations in both gyrB and parE Genes Is Associated with High-Level Resistance to Novobiocin in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/cmr.00042-09openalex-snapshot
Reduced Vancomycin Susceptibility in Staphylococcus aureus , Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications
inferredcites →https://doi.org/10.1128/jb.00027-11openalex-snapshot
Whole-Genome Sequencing of Staphylococcus aureus Strain RN4220, a Key Laboratory Strain Used in Virulence Research, Identifies Mutations That Affect Not Only Virulence Factors but Also the Fitness of the Strain
inferredcites →https://doi.org/10.1128/jb.181.9.2846-2851.1999openalex-snapshot
The Staphylococcus aureus rsbW ( orf159 ) Gene Encodes an Anti-Sigma Factor of SigB
inferredcites →https://doi.org/10.1128/jb.64.4.489-499.1952openalex-snapshot
GENETIC STUDIES ON MICROBIAL CROSS RESISTANCE TO TOXIC AGENTS I. ,
inferredcites →https://doi.org/10.1371/journal.pgen.1002845openalex-snapshot
Rates of Gyrase Supercoiling and Transcription Elongation Control Supercoil Density in a Bacterial Chromosome
inferredcites →https://doi.org/10.1371/journal.pone.0073512openalex-snapshot
Mutation in the C-Di-AMP Cyclase dacA Affects Fitness and Resistance of Methicillin Resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1371/journal.pone.0128036openalex-snapshot
Inexpensive Multiplexed Library Preparation for Megabase-Sized Genomes
inferredcites →https://doi.org/10.1371/journal.ppat.1000944openalex-snapshot
Two Novel Point Mutations in Clinical Staphylococcus aureus Reduce Linezolid Susceptibility and Switch on the Stringent Response to Promote Persistent Infection
inferredcites →https://doi.org/10.1371/journal.ppat.1002217openalex-snapshot
c-di-AMP Is a New Second Messenger in Staphylococcus aureus with a Role in Controlling Cell Size and Envelope Stress
inferredcites →https://doi.org/10.1515/znc-1990-0528openalex-snapshot
Negative Cross Resistance; a Possible Key to Atrazine Resistance Management: A Call for Whole Plant Data
inferredcites →https://doi.org/10.15620/cdc:82532openalex-snapshot
Antibiotic resistance threats in the United States, 2019
inferredcites →https://doi.org/10.1614/0043-1745(2000)048[0176:ncritr]2.0.co;2openalex-snapshot
Negative cross-resistance in triazine-resistant biotypes ofEchinochloa crus-galliandConyza canadensis
inferredcites →https://doi.org/10.6084/m9.figshare.1164194openalex-snapshot
The graph-tool python library
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/bs.ampbs.2024.04.006openalex-snapshot
Staphylococcus aureus response and adaptation to vancomycin
inferred← citeshttps://doi.org/10.1016/j.microb.2024.100086openalex-snapshot
The mechanisms and clinical potential of collateral sensitivity in Mycobacterium tuberculosis: A literature review
inferred← citeshttps://doi.org/10.1016/s1473-3099(19)30045-3openalex-snapshot
Microbial evolutionary medicine: from theory to clinical practice
inferred← citeshttps://doi.org/10.1038/s41467-018-06143-yopenalex-snapshot
Conserved collateral antibiotic susceptibility networks in diverse clinical strains of Escherichia coli
inferred← citeshttps://doi.org/10.1038/s41467-018-08098-6openalex-snapshot
Antibiotic collateral sensitivity is contingent on the repeatability of evolution
inferred← citeshttps://doi.org/10.1038/s41467-020-19713-wopenalex-snapshot
High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli
inferred← citeshttps://doi.org/10.1038/s41467-026-74044-6openalex-snapshot
Mutation-biased adaptation is consequential even in large bacterial populations
inferred← citeshttps://doi.org/10.1038/s41559-025-02804-6openalex-snapshot
Cryptic phenotypic variation emerges rapidly during the adaptive evolution of a carbapenemase
inferred← citeshttps://doi.org/10.1038/s41559-025-02831-3openalex-snapshot
Evolutionary drivers of divergent collateral sensitivity responses during antibiotic therapy
inferred← citeshttps://doi.org/10.1038/s41564-018-0164-0openalex-snapshot
Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides
inferred← citeshttps://doi.org/10.1073/pnas.2507962122openalex-snapshot
Evolution under vancomycin selection drives divergent collateral sensitivity patterns in Staphylococcus aureus
inferred← citeshttps://doi.org/10.1101/185892openalex-snapshot
Antibiotic collateral sensitivity is contingent on the repeatability of evolution
inferred← citeshttps://doi.org/10.1101/2022.08.23.504962openalex-snapshot
Multi-dimensional antibiotic resistance time series reveals the phenotype-based fitness landscape for Escherichia coli
inferred← citeshttps://doi.org/10.1101/2024.09.10.610996openalex-snapshot
Epistasis drives rapid divergence across multiple traits during the adaptive evolution of a carbapenemase
inferred← citeshttps://doi.org/10.1109/bibm47256.2019.8983099openalex-snapshot
Network Analysis of Antibiotic Resistance Identifies Compelling Mutations across Pathways
inferred← citeshttps://doi.org/10.1146/annurev-micro-041522-102707openalex-snapshot
From Petri Dishes to Patients to Populations: Scales and Evolutionary Mechanisms Driving Antibiotic Resistance
inferred← citeshttps://doi.org/10.1371/journal.pbio.3000515openalex-snapshot
Pervasive and diverse collateral sensitivity profiles inform optimal strategies to limit antibiotic resistance
inferred← citeshttps://doi.org/10.1371/journal.pbio.3001920openalex-snapshot
Analysis of the evolution of resistance to multiple antibiotics enables prediction of the Escherichia coli phenotype-based fitness landscape
inferred← citeshttps://doi.org/10.3389/fmicb.2024.1478789openalex-snapshot
Navigating collateral sensitivity: insights into the mechanisms and applications of antibiotic resistance trade-offs
inferred← citeshttps://doi.org/10.7554/elife.51481openalex-snapshot
Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.7554/elife.85023openalex-snapshot
Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance
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