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Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

https://doi.org/10.1101/114405
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archpsyc.60.12.1187openalex-snapshot
Schizophrenia as a Complex Trait
inferredcites →https://doi.org/10.1001/jamapsychiatry.2013.155openalex-snapshot
Schizophrenia Is a Cognitive Illness
inferredcites →https://doi.org/10.1002/ajmg.b.30961openalex-snapshot
Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population
inferredcites →https://doi.org/10.1016/0165-0327(96)00060-2openalex-snapshot
Bipolar disorder, unipolar depression and the Five-Factor Model of personality
inferredcites →https://doi.org/10.1016/j.ajhg.2016.07.020openalex-snapshot
GWIS: Genome-Wide Inferred Statistics for Functions of Multiple Phenotypes
inferredcites →https://doi.org/10.1016/j.nbd.2009.12.013openalex-snapshot
Infragranular gene expression disturbances in the prefrontal cortex in schizophrenia: Signature of altered neural development?
inferredcites →https://doi.org/10.1016/j.paid.2012.02.007openalex-snapshot
The five factor model of personality and intelligence: A twin study on the relationship between the two constructs
inferredcites →https://doi.org/10.1016/j.psychres.2004.09.002openalex-snapshot
Personality traits in schizophrenia and related personality disorders
inferredcites →https://doi.org/10.1016/j.schres.2004.03.002openalex-snapshot
A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1016/j.schres.2006.03.026openalex-snapshot
Do people with a first episode of psychosis differ in personality profiles?
inferredcites →https://doi.org/10.1016/j.tins.2011.01.001openalex-snapshot
Slitrks as emerging candidate genes involved in neuropsychiatric disorders
inferredcites →https://doi.org/10.1016/s0006-3223(98)00046-8openalex-snapshot
Premorbid educational attainment in schizophrenia: association with symptoms, functioning, and neurobehavioral measures
inferredcites →https://doi.org/10.1016/s0140-6736(12)62129-1openalex-snapshot
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
inferredcites →https://doi.org/10.1016/s0378-1119(03)00715-7openalex-snapshot
Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue
inferredcites →https://doi.org/10.1016/s2215-0366(14)70379-7openalex-snapshot
Accumulated environmental risk determining age at schizophrenia onset: a deep phenotyping-based study
inferredcites →https://doi.org/10.1017/s0033291714001512openalex-snapshot
Do premorbid and post-onset cognitive functioning differ between schizophrenia and bipolar disorder? A systematic review and meta-analysis
inferredcites →https://doi.org/10.1037/0033-2909.121.2.219openalex-snapshot
Intelligence, personality, and interests: Evidence for overlapping traits.
inferredcites →https://doi.org/10.1038/mp.2016.208openalex-snapshot
OTTO: a new strategy to extract mental disease-relevant combinations of GWAS hits from individuals
inferredcites →https://doi.org/10.1038/mp.2016.244openalex-snapshot
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
inferredcites →https://doi.org/10.1038/nature09298openalex-snapshot
Integrating common and rare genetic variation in diverse human populations
inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot
An integrated map of genetic variation from 1,092 human genomes
inferredcites →https://doi.org/10.1038/nature12818openalex-snapshot
CNVs conferring risk of autism or schizophrenia affect cognition in controls
inferredcites →https://doi.org/10.1038/nature13595openalex-snapshot
Biological insights from 108 schizophrenia-associated genetic loci
inferredcites →https://doi.org/10.1038/nature17671openalex-snapshot
Genome-wide association study identifies 74 loci associated with educational attainment
inferredcites →https://doi.org/10.1038/ncomms6890openalex-snapshot
Biological interpretation of genome-wide association studies using predicted gene functions
inferredcites →https://doi.org/10.1038/ng.3211openalex-snapshot
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
inferredcites →https://doi.org/10.1038/ng.3285openalex-snapshot
Meta-analysis of the heritability of human traits based on fifty years of twin studies
inferredcites →https://doi.org/10.1038/ng.3404openalex-snapshot
Partitioning heritability by functional annotation using genome-wide association summary statistics
inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot
An atlas of genetic correlations across human diseases and traits
inferredcites →https://doi.org/10.1038/ng.3552openalex-snapshot
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
inferredcites →https://doi.org/10.1038/ng.3869openalex-snapshot
Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence
inferredcites →https://doi.org/10.1038/nn.4040openalex-snapshot
Polygenic risk scores for schizophrenia and bipolar disorder predict creativity
inferredcites →https://doi.org/10.1038/s41588-018-0059-2openalex-snapshot
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
inferredcites →https://doi.org/10.1038/srep27343openalex-snapshot
Slitrk1 is localized to excitatory synapses and promotes their development
inferredcites →https://doi.org/10.1073/pnas.1404623111openalex-snapshot
Common genetic variants associated with cognitive performance identified using the proxy-phenotype method
inferredcites →https://doi.org/10.1086/519795openalex-snapshot
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
inferredcites →https://doi.org/10.1093/bioinformatics/btw615openalex-snapshot
Improved methods for multi-trait fine mapping of pleiotropic risk loci
inferredcites →https://doi.org/10.1093/oxfordjournals.schbul.a007078openalex-snapshot
The Global Costs of Schizophrenia
inferredcites →https://doi.org/10.1093/schbul/18.2.319openalex-snapshot
A Neurodevelopmental Approach to the Classification of Schizophrenia
inferredcites →https://doi.org/10.1093/schbul/sbw085openalex-snapshot
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
inferredcites →https://doi.org/10.1101/022418openalex-snapshot
Haplotypes of common SNPs can explain missing heritability of complex diseases
inferredcites →https://doi.org/10.1101/305029openalex-snapshot
Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits
inferredcites →https://doi.org/10.1101/gad.208926.112openalex-snapshot
FoxO6 regulates memory consolidation and synaptic function
inferredcites →https://doi.org/10.1126/science.1136800openalex-snapshot
Clustering by Passing Messages Between Data Points
inferredcites →https://doi.org/10.1176/appi.ajp.2014.14040516openalex-snapshot
IQ and Schizophrenia in a Swedish National Sample: Their Causal Relationship and the Interaction of IQ With Genetic Risk
inferredcites →https://doi.org/10.1186/1471-244x-10-91openalex-snapshot
The cross-sectional GRAS sample: A comprehensive phenotypical data collection of schizophrenic patients
inferredcites →https://doi.org/10.1186/s13742-015-0047-8openalex-snapshot
Second-generation PLINK: rising to the challenge of larger and richer datasets

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1093/cercor/bhaa146openalex-snapshot
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area
inferred← citeshttps://doi.org/10.3390/ijms19123822openalex-snapshot
Genetic Overlap between General Cognitive Function and Schizophrenia: A Review of Cognitive GWASs
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