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Genetic control of age-related gene expression and complex traits in the human brain
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Mitochondrial DNA Depletion in Respiratory Chain–Deficient P arkinson Disease Neurons
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Identification of Genes from a 500-kb Region at 7q11.23 That Is Commonly Deleted in Williams Syndrome Patients
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Characterization of a Novel Gene Disrupted by a Balanced Chromosomal Translocation t(2;19)(q11.2;q13.3) in a Family with Cleft Lip and Palate
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Galanin – 25 years with a multitalented neuropeptide
inferredcites →https://doi.org/10.1016/j.ajhg.2012.04.023openalex-snapshot
Genetic Architecture of MicroRNA Expression: Implications for the Transcriptome and Complex Traits
inferredcites →https://doi.org/10.1016/j.ajpath.2011.12.008openalex-snapshot
Growth Defects and Impaired Cognitive–Behavioral Abilities in Mice with Knockout for Eif4h, a Gene Located in the Mouse Homolog of the Williams-Beuren Syndrome Critical Region
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ALDOA functions as an oncogene in the highly metastatic pancreatic cancer
inferredcites →https://doi.org/10.1016/j.cub.2012.07.024openalex-snapshot
Ageing as a Risk Factor for Disease
inferredcites →https://doi.org/10.1016/j.mad.2012.07.005openalex-snapshot
Genotype×age interaction in human transcriptional ageing
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2014.06.004openalex-snapshot
Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction
inferredcites →https://doi.org/10.1037/a0019077openalex-snapshot
Conditional routing of information to the cortex: A model of the basal ganglia’s role in cognitive coordination.
inferredcites →https://doi.org/10.1038/72861openalex-snapshot
Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
inferredcites →https://doi.org/10.1038/79171openalex-snapshot
A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C
inferredcites →https://doi.org/10.1038/mp.2011.11openalex-snapshot
Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain
inferredcites →https://doi.org/10.1038/nature10524openalex-snapshot
Temporal dynamics and genetic control of transcription in the human prefrontal cortex
inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot
An integrated map of genetic variation from 1,092 human genomes
inferredcites →https://doi.org/10.1038/nature14248openalex-snapshot
Integrative analysis of 111 reference human epigenomes
inferredcites →https://doi.org/10.1038/ncomms11115openalex-snapshot
Genetic and environmental influences interact with age and sex in shaping the human methylome
inferredcites →https://doi.org/10.1038/ng.803openalex-snapshot
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
inferredcites →https://doi.org/10.1038/ng.859openalex-snapshot
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
inferredcites →https://doi.org/10.1038/ng1914openalex-snapshot
Diversity of microRNAs in human and chimpanzee brain
inferredcites →https://doi.org/10.1038/ng826openalex-snapshot
Identification of a variant associated with adult-type hypolactasia
inferredcites →https://doi.org/10.1038/nm0798-827openalex-snapshot
Aging renders the brain vulnerable to amyloid β-protein neurotoxicity
inferredcites →https://doi.org/10.1038/nmeth.4298openalex-snapshot
Allele-specific expression reveals interactions between genetic variation and environment
inferredcites →https://doi.org/10.1038/nprot.2009.97openalex-snapshot
Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt
inferredcites →https://doi.org/10.1038/nprot.2011.457openalex-snapshot
Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses
inferredcites →https://doi.org/10.1038/srep15145openalex-snapshot
Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases
inferredcites →https://doi.org/10.1042/bst029a029copenalex-snapshot
Mutations in the gene encoding peroxisomal α-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
inferredcites →https://doi.org/10.1073/pnas.0900544106openalex-snapshot
Transcriptional neoteny in the human brain
inferredcites →https://doi.org/10.1086/426734openalex-snapshot
Mapping of a Major Locus that Determines Telomere Length in Humans
inferredcites →https://doi.org/10.1093/bioinformatics/bts163openalex-snapshot
Matrix eQTL: ultra fast eQTL analysis via large matrix operations
inferredcites →https://doi.org/10.1093/bioinformatics/btu168openalex-snapshot
VariantAnnotation : a Bioconductor package for exploration and annotation of genetic variants
inferredcites →https://doi.org/10.1093/bioinformatics/btu273openalex-snapshot
GRASP: analysis of genotype–phenotype results from 1390 genome-wide association studies and corresponding open access database
inferredcites →https://doi.org/10.1093/gerona/glu057openalex-snapshot
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
inferredcites →https://doi.org/10.1093/hmg/8.4.711openalex-snapshot
Association of an Extended Haplotype in the Tau Gene with Progressive Supranuclear Palsy
inferredcites →https://doi.org/10.1093/hmg/ddq561openalex-snapshot
Distinct DNA methylation changes highly correlated with chronological age in the human brain
inferredcites →https://doi.org/10.1093/hmg/ddt582openalex-snapshot
Sex- and age-interacting eQTLs in human complex diseases
inferredcites →https://doi.org/10.1093/hmg/ddv213openalex-snapshot
The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development
inferredcites →https://doi.org/10.1093/nar/gkj112openalex-snapshot
miRBase: microRNA sequences, targets and gene nomenclature
inferredcites →https://doi.org/10.1093/nar/gkr378openalex-snapshot
g:Profiler—a web server for functional interpretation of gene lists (2011 update)
inferredcites →https://doi.org/10.1093/nar/gkv1258openalex-snapshot
miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database
inferredcites →https://doi.org/10.1101/gr.135350.111openalex-snapshot
GENCODE: The reference human genome annotation for The ENCODE Project
inferredcites →https://doi.org/10.1111/1467-9868.00346openalex-snapshot
A Direct Approach to False Discovery Rates
inferredcites →https://doi.org/10.1111/acel.12373openalex-snapshot
Circulating micro RNA signature of genotype‐by‐age interactions in the long‐lived A mes dwarf mouse
inferredcites →https://doi.org/10.1126/science.1149460openalex-snapshot
Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation
inferredcites →https://doi.org/10.1126/science.1262110openalex-snapshot
The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
inferredcites →https://doi.org/10.1186/gb-2013-14-7-r75openalex-snapshot
Gene expression changes with age in skin, adipose tissue, blood and brain
inferredcites →https://doi.org/10.1371/journal.pbio.0030274openalex-snapshot
Aging and Gene Expression in the Primate Brain
inferredcites →https://doi.org/10.1371/journal.pgen.1000952openalex-snapshot
Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain
inferredcites →https://doi.org/10.1371/journal.pgen.1005728openalex-snapshot
Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity
inferredcites →https://doi.org/10.1371/journal.pgen.1006382openalex-snapshot
Local Adaptation of Sun-Exposure-Dependent Gene Expression Regulation in Human Skin
inferredcites →https://doi.org/10.3389/fendo.2015.00013openalex-snapshot
Insulin, Aging, and the Brain: Mechanisms and Implications
inferredcites →https://doi.org/10.3389/fnagi.2016.00183openalex-snapshot
Aging Shapes the Population-Mean and -Dispersion of Gene Expression in Human Brains
inferredcites →https://doi.org/10.3389/fncel.2013.00220openalex-snapshot
miR-9: a versatile regulator of neurogenesis
inferredcites →https://doi.org/10.3892/ijo.2016.3814openalex-snapshot
Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis
inferredcites →https://doi.org/10.7554/elife.00523openalex-snapshot
Passive and active DNA methylation and the interplay with genetic variation in gene regulation
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.jalz.2018.01.015openalex-snapshot
The effects of the TOMM40 poly‐T alleles on Alzheimer's disease phenotypes
inferred← citeshttps://doi.org/10.3389/fpsyt.2022.1102347openalex-snapshot
Are Alzheimer's and coronary artery diseases genetically related to longevity?
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