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Anti-HIV activity prediction and enrichment identify novel human targets for Anti-HIV therapy

https://doi.org/10.1101/159236
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Genome-Scale RNAi Screen for Host Factors Required for HIV Replication
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Virus–host interactomes — antiviral drug discovery
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MicroRNAs and HIV-1 Infection: Antiviral Activities and Beyond
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Using Support Vector Machine to identify imaging biomarkers of neurological and psychiatric disease: A critical review
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A Tutorial on Support Vector Machines for Pattern Recognition
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Random Forests
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Viral exploitation and subversion of the immune system through chemokine mimicry
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Global landscape of HIV–human protein complexes
inferredcites →https://doi.org/10.1038/ng.3741openalex-snapshot
A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors
inferredcites →https://doi.org/10.1038/nmeth.2689openalex-snapshot
DGIdb: mining the druggable genome
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Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
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The druggable genome
inferredcites →https://doi.org/10.1038/nrm1529openalex-snapshot
Viral hijacking of G-protein-coupled-receptor signalling networks
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Systems virology: host-directed approaches to viral pathogenesis and drug targeting
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In silico identification of anti-cancer compounds and plants from traditional Chinese medicine database
inferredcites →https://doi.org/10.1093/bioinformatics/bti654openalex-snapshot
Computational methods for the design of effective therapies against drug resistant HIV strains
inferredcites →https://doi.org/10.1093/bioinformatics/bts625openalex-snapshot
CDRUG: a web server for predicting anticancer activity of chemical compounds
inferredcites →https://doi.org/10.1093/bioinformatics/btt606openalex-snapshot
Inferring therapeutic targets from heterogeneous data: HKDC1 is a novel potential therapeutic target for cancer
inferredcites →https://doi.org/10.1093/nar/30.1.412openalex-snapshot
TTD: Therapeutic Target Database
inferredcites →https://doi.org/10.1093/nar/gkm958openalex-snapshot
DrugBank: a knowledgebase for drugs, drug actions and drug targets
inferredcites →https://doi.org/10.1093/nar/gkq537openalex-snapshot
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
inferredcites →https://doi.org/10.1093/nar/gkr777openalex-snapshot
ChEMBL: a large-scale bioactivity database for drug discovery
inferredcites →https://doi.org/10.1093/nar/gku1126openalex-snapshot
HIV-1, human interaction database: current status and new features
inferredcites →https://doi.org/10.1093/nar/gkv1230openalex-snapshot
Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information
inferredcites →https://doi.org/10.1093/nar/gkw1074openalex-snapshot
The ChEMBL database in 2017
inferredcites →https://doi.org/10.1093/oxfordjournals.jncimonographs.a024259openalex-snapshot
Role of the National Cancer Institute in Acquired Immunodeficiency Syndrome-Related Drug Discovery
inferredcites →https://doi.org/10.1097/coh.0b013e328324bbecopenalex-snapshot
The biology of CCR5 and CXCR4
inferredcites →https://doi.org/10.1101/gr.1239303openalex-snapshot
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
inferredcites →https://doi.org/10.1111/2049-632x.12150openalex-snapshot
Proteomic strategies for the discovery of novel diagnostic and therapeutic targets for infectious diseases
inferredcites →https://doi.org/10.1145/1961189.1961199openalex-snapshot
LIBSVM
inferredcites →https://doi.org/10.1146/annurev-genom-091212-153406openalex-snapshot
Deep Sequencing of HIV: Clinical and Research Applications
inferredcites →https://doi.org/10.1146/annurev-med-052511-135400openalex-snapshot
Host Genetics of HIV Acquisition and Viral Control
inferredcites →https://doi.org/10.1146/annurev-med-052912-123749openalex-snapshot
Lessons from the RV144 Thai Phase III HIV-1 Vaccine Trial and the Search for Correlates of Protection
inferredcites →https://doi.org/10.1146/annurev-med-091014-090749openalex-snapshot
Broadly Neutralizing Antibodies Against HIV: New Insights to Inform Vaccine Design
inferredcites →https://doi.org/10.1186/1471-2105-11-101openalex-snapshot
Extracting causal relations on HIV drug resistance from literature
inferredcites →https://doi.org/10.1186/1752-153x-2-5openalex-snapshot
Pybel: a Python wrapper for the OpenBabel cheminformatics toolkit
inferredcites →https://doi.org/10.1186/1758-2946-3-33openalex-snapshot
Open Babel: An open chemical toolbox
inferredcites →https://doi.org/10.1186/gb-2013-14-1-201openalex-snapshot
Host genomic influences on HIV/AIDS
inferredcites →https://doi.org/10.12688/f1000research.4572.1openalex-snapshot
GeneMANIA: Fast gene network construction and function prediction for Cytoscape
inferredcites →https://doi.org/10.1371/journal.pone.0065207openalex-snapshot
Identifying Chemicals with Potential Therapy of HIV Based on Protein-Protein and Protein-Chemical Interaction Network
inferredcites →https://doi.org/10.1517/14712590903257781openalex-snapshot
Novel HIV-1 therapeutics through targeting altered host cell pathways
inferredcites →https://doi.org/10.1517/17460441.2015.975201openalex-snapshot
Latest animal models for anti-HIV drug discovery
inferredcites →https://doi.org/10.18637/jss.v064.i04openalex-snapshot
fitdistrplus : An R Package for Fitting Distributions
inferredcites →https://doi.org/10.18637/jss.v064.i07openalex-snapshot
PReMiuM : An R Package for Profile Regression Mixture Models Using Dirichlet Processes
inferredcites →https://doi.org/10.2174/1568026616999151013124606openalex-snapshot
Why Do We Need New Drug Classes for HIV Treatment and Prevention?
inferredcites →https://doi.org/10.48550/arxiv.1201.0490openalex-snapshot
Scikit-learn: Machine Learning in Python
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