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Cell shape regulates subcellular organelle location to control early Ca 2+ signal dynamics in Vascular Smooth Muscle Cells

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Calcium signalling and cell proliferation
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Systems biology of cellular membranes: a convergence with biophysics
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Equations for InsP3 Receptor-mediated [Ca2+]i Oscillations Derived from a Detailed Kinetic Model: A Hodgkin-Huxley Like Formalism
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Molecular Cell Biology of Atherosclerosis
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Regulation and characteristics of vascular smooth muscle cell phenotypic diversity
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Muscarinic Receptors—Characterization, coupling and function
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Muscarinic acetylcholine receptor subtypes in smooth muscle
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Emerging Roles for Native Orai Ca2+ Channels in Cardiovascular Disease
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Inositol trisphosphate and calcium signalling mechanisms
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Kinetics of calmodulin binding to calcineurin
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Shear-Induced Nitric Oxide Production by Endothelial Cells
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The road much traveled: trafficking in the cell nucleus
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Cell Shape and Negative Links in Regulatory Motifs Together Control Spatial Information Flow in Signaling Networks
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Decoding Information in Cell Shape
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Potential for Control of Signaling Pathways via Cell Size and Shape
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Spatially distributed cell signalling
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Regulation of vascular smooth muscle cell differentiation
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Contractile role of M2 and M3 muscarinic receptors in gastrointestinal, airway and urinary bladder smooth muscle
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Stabilizers and Destabilizers Controlling Cell Cycle Oscillators
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Coactivation of MEF2 by the SAP Domain Proteins Myocardin and MASTR
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Spatial-temporal patterning of Ca2+ signals by the subcellular distribution of IP3 and IP3 receptors
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An Image-Based Model of Calcium Waves in Differentiated Neuroblastoma Cells
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Distribution of Proteins Implicated in Excitation-Contraction Coupling in Rat Ventricular Myocytes
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Signal-Regulated Activation of Serum Response Factor Is Mediated by Changes in Actin Dynamics
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Activation of Cardiac Gene Expression by Myocardin, a Transcriptional Cofactor for Serum Response Factor
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The Virtual Cell: a software environment for computational cell biology
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Endoplasmic reticulum membrane tubules are distributed by microtubules in living cells using three distinct mechanisms
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Mathematical Models of Protein Kinase Signal Transduction
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Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment
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Streamlined Embedding of Cell Monolayers on Gridded Glass-Bottom Imaging Dishes for Correlative Light and Electron Microscopy
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A Role for G-Proteins in Directing G-Protein-Coupled Receptor–Caveolae Localization
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Cardiac excitation–contraction coupling
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Nonlinear elasticity in biological gels
inferredcites →https://doi.org/10.1038/nature07577openalex-snapshot
Calcium flickers steer cell migration
inferredcites →https://doi.org/10.1038/nature22369openalex-snapshot
Applying systems-level spectral imaging and analysis to reveal the organelle interactome
inferredcites →https://doi.org/10.1038/nchembio.1611openalex-snapshot
Endosomal generation of cAMP in GPCR signaling
inferredcites →https://doi.org/10.1038/ncomms1668openalex-snapshot
Spatial coordination between cell and nuclear shape within micropatterned endothelial cells
inferredcites →https://doi.org/10.1038/nmeth.1462openalex-snapshot
Probabilistic density maps to study global endomembrane organization
inferredcites →https://doi.org/10.1038/nprot.2009.234openalex-snapshot
Soft lithography for micro- and nanoscale patterning
inferredcites →https://doi.org/10.1038/nrm1890openalex-snapshot
Local force and geometry sensing regulate cell functions
inferredcites →https://doi.org/10.1038/nrm2901openalex-snapshot
Signalling ballet in space and time
inferredcites →https://doi.org/10.1038/onc.2008.308openalex-snapshot
Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis
inferredcites →https://doi.org/10.1038/s41467-017-02218-4openalex-snapshot
Cell shape information is transduced through tension-independent mechanisms
inferredcites →https://doi.org/10.1038/s41598-019-48028-0openalex-snapshot
Geometric principles of second messenger dynamics in dendritic spines
inferredcites →https://doi.org/10.1038/sj.bjp.0702234openalex-snapshot
The effect of inhibitors of receptor internalization on the desensitization and resensitization of three Gs‐coupled receptor responses
inferredcites →https://doi.org/10.1039/c1ib00061fopenalex-snapshot
Vascular smooth muscle contractility depends on cell shape
inferredcites →https://doi.org/10.1039/c3ib40230dopenalex-snapshot
The contractile strength of vascular smooth muscle myocytes is shape dependent
inferredcites →https://doi.org/10.1073/pnas.0308742101openalex-snapshot
Real-time evaluation of myosin light chain kinase activation in smooth muscle tissues from a transgenic calmodulin-biosensor mouse
inferredcites →https://doi.org/10.1073/pnas.1300801110openalex-snapshot
Cell geometric constraints induce modular gene-expression patterns via redistribution of HDAC3 regulated by actomyosin contractility
inferredcites →https://doi.org/10.1073/pnas.1610391113openalex-snapshot
Paradoxical signaling regulates structural plasticity in dendritic spines
inferredcites →https://doi.org/10.1073/pnas.1617705114openalex-snapshot
Design principles for robust vesiculation in clathrin-mediated endocytosis
inferredcites →https://doi.org/10.1073/pnas.1618007114openalex-snapshot
Cell geometry dictates TNFα-induced genome response
inferredcites →https://doi.org/10.1073/pnas.1701078114openalex-snapshot
Contacts between the endoplasmic reticulum and other membranes in neurons
inferredcites →https://doi.org/10.1073/pnas.89.20.9895openalex-snapshot
A single-pool inositol 1,4,5-trisphosphate-receptor-based model for agonist-stimulated oscillations in Ca2+ concentration.
inferredcites →https://doi.org/10.1074/jbc.r000024200openalex-snapshot
Calcium, Calcineurin, and the Control of Transcription
inferredcites →https://doi.org/10.1083/jcb.108.2.389openalex-snapshot
Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation.
inferredcites →https://doi.org/10.1083/jcb.121.1.61openalex-snapshot
Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification.
inferredcites →https://doi.org/10.1083/jcb.147.5.929openalex-snapshot
Morphological Control of Inositol-1,4,5-Trisphosphate–Dependent Signals
inferredcites →https://doi.org/10.1083/jcb.200301070openalex-snapshot
Kinetic analysis of receptor-activated phosphoinositide turnover
inferredcites →https://doi.org/10.1083/jcb.201004003openalex-snapshot
Cell shape and contractility regulate ciliogenesis in cell cycle–arrested cells
inferredcites →https://doi.org/10.1083/jcb.2111oia229openalex-snapshot
Diffusion of myosin light chain kinase on actin: A mechanism to enhance myosin phosphorylation rates in smooth muscle
inferredcites →https://doi.org/10.1085/jgp.201812261openalex-snapshot
Dendritic spine geometry and spine apparatus organization govern the spatiotemporal dynamics of calcium
inferredcites →https://doi.org/10.1093/cvr/cvs115openalex-snapshot
Smooth muscle cell phenotypic switching in atherosclerosis
inferredcites →https://doi.org/10.1093/embo-reports/kvf202openalex-snapshot
Structural organization of the endoplasmic reticulum
inferredcites →https://doi.org/10.1098/rsob.130132openalex-snapshot
Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity
inferredcites →https://doi.org/10.1101/gad.1102703openalex-snapshot
Transcriptional regulation by calcium, calcineurin, and NFAT
inferredcites →https://doi.org/10.1103/physreve.75.041915openalex-snapshot
Diffusion-trapping model of receptor trafficking in dendrites
inferredcites →https://doi.org/10.1103/revmodphys.85.135openalex-snapshot
Stochastic models of intracellular transport
inferredcites →https://doi.org/10.1111/febs.12414openalex-snapshot
Vascular smooth muscle cell phenotype is defined by C a2+‐dependent transcription factors
inferredcites →https://doi.org/10.1111/j.1469-7793.1998.199br.xopenalex-snapshot
Regulation of arterial diameter and wall [Ca2+] in cerebral arteries of rat by membrane potential and intravascular pressure
inferredcites →https://doi.org/10.1111/j.1474-9726.2007.00296.xopenalex-snapshot
The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging
inferredcites →https://doi.org/10.1113/jphysiol.2012.233353openalex-snapshot
STIM/Orai signalling complexes in vascular smooth muscle
inferredcites →https://doi.org/10.1124/pr.115.010652openalex-snapshot
Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders
inferredcites →https://doi.org/10.1126/science.1071550openalex-snapshot
G Protein Pathways
inferredcites →https://doi.org/10.1126/science.1140324openalex-snapshot
Quantitative Morphological Signatures Define Local Signaling Networks Regulating Cell Morphology
inferredcites →https://doi.org/10.1126/science.1175862openalex-snapshot
Actin, a Central Player in Cell Shape and Movement
inferredcites →https://doi.org/10.1126/science.283.5400.381openalex-snapshot
Emergent Properties of Networks of Biological Signaling Pathways
inferredcites →https://doi.org/10.1126/science.284.5419.1527openalex-snapshot
Spatiotemporal Dynamics of Inositol 1,4,5-Trisphosphate That Underlies Complex Ca 2+ Mobilization Patterns
inferredcites →https://doi.org/10.1126/science.8122111openalex-snapshot
Suppression of Ras-Induced Transformation of NIH 3T3 Cells by Activated Gα S
inferredcites →https://doi.org/10.1126/scisignal.aag1625openalex-snapshot
Hindered cytoplasmic diffusion of inositol trisphosphate restricts its cellular range of action
inferredcites →https://doi.org/10.1128/mcb.15.7.3672openalex-snapshot
Calcium Activates Serum Response Factor-Dependent Transcription By A Ras- and Elk-1-Independent Mechanism That Involves a Ca 2+ /Calmodulin-Dependent Kinase
inferredcites →https://doi.org/10.1152/ajpcell.00198.2006openalex-snapshot
Regulation of myosin light chain kinase and telokin expression in smooth muscle tissues
inferredcites →https://doi.org/10.1152/ajpcell.00280.2003openalex-snapshot
Extracellular matrix controls myosin light chain phosphorylation and cell contractility through modulation of cell shape and cytoskeletal prestress
inferredcites →https://doi.org/10.1152/ajpcell.90645.2007openalex-snapshot
Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo
inferredcites →https://doi.org/10.1152/physrev.00012.2013openalex-snapshot
Dendritic Spines: The Locus of Structural and Functional Plasticity
inferredcites →https://doi.org/10.1152/physrev.00018.2008openalex-snapshot
Sarcoplasmic Reticulum Function in Smooth Muscle
inferredcites →https://doi.org/10.1152/physrev.00023.2005openalex-snapshot
Calcium at Fertilization and in Early Development
inferredcites →https://doi.org/10.1152/physrev.00041.2003openalex-snapshot
Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease
inferredcites →https://doi.org/10.1152/physrev.1979.59.1.1openalex-snapshot
The smooth muscle cell in culture
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Regulation of differentiation of vascular smooth muscle cells
inferredcites →https://doi.org/10.1165/rcmb.2002-0206ocopenalex-snapshot
The RhoA/Rho Kinase Pathway Regulates Nuclear Localization of Serum Response Factor
inferredcites →https://doi.org/10.1253/circj.cj-08-1041openalex-snapshot
Phosphorylation of Myosin Regulatory Light Chain by Myosin Light Chain Kinase, and Muscle Contraction
inferredcites →https://doi.org/10.1371/journal.pcbi.1007756openalex-snapshot
3D mesh processing using GAMer 2 to enable reaction-diffusion simulations in realistic cellular geometries
inferredcites →https://doi.org/10.1371/journal.pone.0069598openalex-snapshot
Activation of Store-Operated Calcium Entry in Airway Smooth Muscle Cells: Insight from a Mathematical Model
inferredcites →https://doi.org/10.1529/biophysj.103.035253openalex-snapshot
A Signal Transduction Pathway Model Prototype I: From Agonist to Cellular Endpoint
inferredcites →https://doi.org/10.1529/biophysj.106.081562openalex-snapshot
Membrane-Bound Basic Peptides Sequester Multivalent (PIP2), but Not Monovalent (PS), Acidic Lipids
inferredcites →https://doi.org/10.1529/biophysj.106.093104openalex-snapshot
Compartment-Specific Feedback Loop and Regulated Trafficking Can Result in Sustained Activation of Ras at the Golgi
inferredcites →https://doi.org/10.1529/biophysj.107.110031openalex-snapshot
Modeling Hypertrophic IP3 Transients in the Cardiac Myocyte
inferredcites →https://doi.org/10.1529/biophysj.107.121335openalex-snapshot
Mechanical and Biochemical Modeling of Cortical Oscillations in Spreading Cells
inferredcites →https://doi.org/10.1529/biophysj.108.138974openalex-snapshot
Spatial Diffusivity and Availability of Intracellular Calmodulin
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Introduction to Differential Geometry and Riemannian Geometry
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Applications and Challenges of Machine Learning to Enable Realistic Cellular Simulations
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Ca2+-dependent calcineurin/NFAT signaling in β-adrenergic-induced cardiac hypertrophy
inferredcites →https://doi.org/10.7554/elife.06156.041openalex-snapshot
Author response: Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Three-dimensional analysis of hydrogel-imbedded aortic valve interstitial cell shape and its relation to contractile behavior
inferred← citeshttps://doi.org/10.1016/j.bpj.2019.09.034openalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41540-021-00185-7openalex-snapshot
Systems modeling predicts that mitochondria ER contact sites regulate the postsynaptic energy landscape
inferred← citeshttps://doi.org/10.1038/s41598-019-48028-0openalex-snapshot
Geometric principles of second messenger dynamics in dendritic spines
inferred← citeshttps://doi.org/10.1085/jgp.201812261openalex-snapshot
Dendritic spine geometry and spine apparatus organization govern the spatiotemporal dynamics of calcium
inferred← citeshttps://doi.org/10.1101/534479openalex-snapshot
GAMer 2: A System for 3D Mesh Processing of Cellular Electron Micrographs
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Gq-mediated calcium dynamics and membrane tension modulate neurite plasticity
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