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GAS Power Calculator: web-based power calculator for genetic association studies

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1038/nature15393openalex-snapshot
A global reference for human genetic variation
inferredcites →https://doi.org/10.1038/ng.2507openalex-snapshot
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
inferredcites →https://doi.org/10.1038/ng1706openalex-snapshot
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
inferredcites →https://doi.org/10.1038/nrg.2016.49openalex-snapshot
Coming of age: ten years of next-generation sequencing technologies
inferredcites →https://doi.org/10.1038/nrg2344openalex-snapshot
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
inferredcites →https://doi.org/10.1080/09332480.2005.10722754openalex-snapshot
Why Most Published Research Findings Are False
inferredcites →https://doi.org/10.1093/bioinformatics/19.1.149openalex-snapshot
Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits
inferredcites →https://doi.org/10.1093/nar/gkt1229openalex-snapshot
The NHGRI GWAS Catalog, a curated resource of SNP-trait associations
inferredcites →https://doi.org/10.2307/2346800openalex-snapshot
Algorithm AS 66: The Normal Integral
inferredcites →https://doi.org/10.2307/2347330openalex-snapshot
Algorithm AS 241: The Percentage Points of the Normal Distribution

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1002/alz.14592openalex-snapshot
Identification of 16 novel Alzheimer's disease loci using multi‐ancestry meta‐analyses
inferred← citeshttps://doi.org/10.1002/ana.26416openalex-snapshot
Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors
inferred← citeshttps://doi.org/10.1002/gepi.22216openalex-snapshot
PAMAM: Power analysis in multiancestry admixture mapping
inferred← citeshttps://doi.org/10.1002/gepi.22588openalex-snapshot
Genetic Associations of Persistent Opioid Use After Surgery Point to OPRM1 but Not Other Opioid‐Related Loci as the Main Driver of Opioid Use Disorder
inferred← citeshttps://doi.org/10.1002/imo2.18openalex-snapshot
Cohort profile: A longitudinal multi‐omics cohort of patients with acute coronary syndrome
inferred← citeshttps://doi.org/10.1002/jcla.25026openalex-snapshot
Association of the ESR1 (rs9340799), OLR1 (rs3736234), LIPC (rs2070895), VDR (rs2228570), and CETP (rs708272) Polymorphisms With Risk of Coronary Artery Disease in Iranian Patients
inferred← citeshttps://doi.org/10.1002/mp.13751openalex-snapshot
Genomics models in radiotherapy: From mechanistic to machine learning
inferred← citeshttps://doi.org/10.1007/978-3-319-72938-1_9openalex-snapshot
Genetic Risk Factors for Sporadic Frontotemporal Dementia
inferred← citeshttps://doi.org/10.1007/s10048-017-0529-1openalex-snapshot
Identification of rare noncoding sequence variants in gamma-aminobutyric acid A receptor, alpha 4 subunit in autism spectrum disorder
inferred← citeshttps://doi.org/10.1007/s10519-024-10187-wopenalex-snapshot
Using Alternative Definitions of Controls to Increase Statistical Power in GWAS
inferred← citeshttps://doi.org/10.1007/s10528-021-10089-0openalex-snapshot
A Study of Associations Between rs9349379 (PHACTR1), rs2891168 (CDKN2B-AS), rs11838776 (COL4A2) and rs4880 (SOD2) Polymorphic Variants and Coronary Artery Disease in Iranian Population
inferred← citeshttps://doi.org/10.1016/j.euo.2018.08.020openalex-snapshot
Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non–muscle-invasive Bladder Cancer
inferred← citeshttps://doi.org/10.1016/j.gene.2023.147264openalex-snapshot
SPP1 and UMOD gene variants are synergistically associated with risk of renal stone disease
inferred← citeshttps://doi.org/10.1016/j.joen.2023.07.018openalex-snapshot
Genome-wide Association Study Identifies Novel Risk Loci for Apical Periodontitis
inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2021.03.006openalex-snapshot
Assessment of ANG variants in Parkinson's disease
inferred← citeshttps://doi.org/10.1017/thg.2020.60openalex-snapshot
Septic Shock: A Genomewide Association Study and Polygenic Risk Score Analysis
inferred← citeshttps://doi.org/10.1038/s41467-019-08469-7openalex-snapshot
Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations
inferred← citeshttps://doi.org/10.1038/s41467-025-62319-3openalex-snapshot
Exome analysis links kidney malformations to developmental disorders and reveals causal genes
inferred← citeshttps://doi.org/10.1038/s41598-021-81836-xopenalex-snapshot
Replication of HLA class II locus association with susceptibility to podoconiosis in three Ethiopian ethnic groups
inferred← citeshttps://doi.org/10.1038/s41598-021-84042-xopenalex-snapshot
rs1944919 on chromosome 11q23.1 and its effector genes COLCA1/COLCA2 confer susceptibility to primary biliary cholangitis
inferred← citeshttps://doi.org/10.1038/s41598-022-24931-xopenalex-snapshot
Risk of type 2 diabetes and KCNJ11 gene polymorphisms: a nested case–control study and meta-analysis
inferred← citeshttps://doi.org/10.1038/s42003-022-03554-yopenalex-snapshot
Considering hormone-sensitive cancers as a single disease in the UK biobank reveals shared aetiology
inferred← citeshttps://doi.org/10.1053/j.gastro.2019.09.041openalex-snapshot
HLA-DQA1*05 Carriage Associated With Development of Anti-Drug Antibodies to Infliximab and Adalimumab in Patients With Crohn’s Disease
inferred← citeshttps://doi.org/10.1073/pnas.2106844118openalex-snapshot
Systems biology analysis of human genomes points to key pathways conferring spina bifida risk
inferred← citeshttps://doi.org/10.1080/08820139.2019.1622561openalex-snapshot
Impact of IL12B Polymorphisms on Genetic Susceptibility and IL-12p40 and IL-23 Serum Levels in Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.1080/13506129.2020.1758658openalex-snapshot
Transthyretin-stabilising mutation T119M is not associated with protection against vascular disease or death in the UK Biobank
inferred← citeshttps://doi.org/10.1080/14737159.2024.2421497openalex-snapshot
Lipid-associated GWAS loci as important markers of the risk, severity, and clinical course of peripheral artery disease
inferred← citeshttps://doi.org/10.1080/14737159.2024.2436399openalex-snapshot
Exploring sex-specific genetic architecture of coronary artery disease in Tehran: a cardiometabolic genetic study
inferred← citeshttps://doi.org/10.1080/22221751.2021.1878936openalex-snapshot
Genetic variants in human BCL2L11 ( BIM ) are associated with ulcerative forms of Buruli ulcer
inferred← citeshttps://doi.org/10.1093/bioadv/vbaf150openalex-snapshot
EpipwR: efficient power analysis for EWAS with continuous outcomes
inferred← citeshttps://doi.org/10.1093/bioinformatics/btz637openalex-snapshot
U-PASS: unified power analysis and forensics for qualitative traits in genetic association studies
inferred← citeshttps://doi.org/10.1093/gbe/evaa250openalex-snapshot
The Population-Specific Impact of Neandertal Introgression on Human Disease
inferred← citeshttps://doi.org/10.1093/ntr/ntaf009openalex-snapshot
Genome-Wide Association Study of Varenicline-Aided Smoking Cessation
inferred← citeshttps://doi.org/10.1101/19011999openalex-snapshot
Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma
inferred← citeshttps://doi.org/10.1101/2021.09.08.21254232openalex-snapshot
Genome-wide association study of REM sleep behavior disorder identifies novel loci with distinct polygenic and brain expression effects
inferred← citeshttps://doi.org/10.1101/2021.12.19.473339openalex-snapshot
MOPower: an R-shiny application for the simulation and power calculation of multi-omics studies
inferred← citeshttps://doi.org/10.1101/2023.04.14.23288478openalex-snapshot
Genome-wide association study stratified by MAPT haplotypes identifies potential novel loci in Parkinson’s disease
inferred← citeshttps://doi.org/10.1101/2024.09.11.24313439openalex-snapshot
Identification of 16 novel Alzheimer’s disease susceptibility loci using multi-ancestry meta-analyses of clinical Alzheimer’s disease and AD-by-proxy cases from four whole genome sequencing datasets
inferred← citeshttps://doi.org/10.1101/2025.01.14.25320563openalex-snapshot
The impact of Indigenous American-like ancestry on risk of acute lymphoblastic leukemia in Hispanic/Latino children
inferred← citeshttps://doi.org/10.1101/2025.03.18.25324218openalex-snapshot
Genome-wide association study of dry eye disease reveals shared heritability with systemic comorbidities
inferred← citeshttps://doi.org/10.1101/2025.03.19.25324246openalex-snapshot
Genetic Determinants of Major Depressive Disorder among Adult Persons Living With HIV in Uganda
inferred← citeshttps://doi.org/10.1111/gbb.12580openalex-snapshot
Genome‐wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward‐related ventral striatum activity in African‐ and European‐Americans
inferred← citeshttps://doi.org/10.1111/iej.13879openalex-snapshot
TNFSF13B rs9514828 gene polymorphism and soluble B cell activating factor levels: Association with apical periodontitis
inferred← citeshttps://doi.org/10.1126/science.aay8833openalex-snapshot
Genetics of schizophrenia in the South African Xhosa
inferred← citeshttps://doi.org/10.1136/gutjnl-2022-327196openalex-snapshot
Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study
inferred← citeshttps://doi.org/10.1146/annurev-genom-083117-021641openalex-snapshot
Rare-Variant Studies to Complement Genome-Wide Association Studies
inferred← citeshttps://doi.org/10.1155/2024/9990112openalex-snapshot
The Catechol‐O‐Methyltransferase (COMT) Val158Met Polymorphism Is Associated with Oxycodone Requirements, Adverse Effects, and Pain Sensitivity in Cancer Patients
inferred← citeshttps://doi.org/10.1177/02698811211032609openalex-snapshot
Association study of BDNF Val66Met gene polymorphism with bipolar disorder and lithium treatment response in Indian population
inferred← citeshttps://doi.org/10.1177/13872877251350722openalex-snapshot
An ABCA1 missense variant decreases cholesterol efflux and confers Alzheimer's disease risk in the Chinese population
inferred← citeshttps://doi.org/10.1182/bloodadvances.2025016282openalex-snapshot
Genome-wide association study of somatic GATA1s mutations in newborns with Down syndrome
inferred← citeshttps://doi.org/10.1186/s10194-025-02218-6openalex-snapshot
L3MBTL2 as a novel therapeutic target for trigeminal neuralgia: evidence from integrated TWAS, multi-tissue MR, and experimental validation
inferred← citeshttps://doi.org/10.1186/s12864-021-07635-wopenalex-snapshot
Hierarchicell: an R-package for estimating power for tests of differential expression with single-cell data
inferred← citeshttps://doi.org/10.1186/s13098-021-00782-wopenalex-snapshot
CDKAL1 gene rs7756992 A/G and rs7754840 G/C polymorphisms are associated with gestational diabetes mellitus in a sample of Bangladeshi population: implication for future T2DM prophylaxis
inferred← citeshttps://doi.org/10.1186/s40360-025-01022-xopenalex-snapshot
Impact of SLCO1B1 (rs2306283) polymorphism on personalized atorvastatin dosing in a genetically distinct South Asian cohort
inferred← citeshttps://doi.org/10.1186/s43043-026-00324-2openalex-snapshot
A genome-wide association study identifies GNPNAT1 as a candidate risk locus for endometriosis in the Tehran Cardio-metabolic genetic study
inferred← citeshttps://doi.org/10.1371/journal.pgen.1008203openalex-snapshot
scoreInvHap: Inversion genotyping for genome-wide association studies
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3175786/v1openalex-snapshot
Genetic associations of persistent opioid use after surgery: a hypothesis-driven analysis of high-value genetic variants in the Michigan Genomics Initiative dataset
inferred← citeshttps://doi.org/10.21203/rs.3.rs-873449/v1openalex-snapshot
False discovery rates for genome-wide association tests in biobanks with thousands of phenotypes
inferred← citeshttps://doi.org/10.31083/fbs42728openalex-snapshot
Uterine Fibroids-Associated GWAS Loci and the Risk of Arterial Hypertension: A Pilot Study
inferred← citeshttps://doi.org/10.3324/haematol.2020.247023openalex-snapshot
Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma
inferred← citeshttps://doi.org/10.3389/fgene.2022.948505openalex-snapshot
Genome-wide association study for systemic lupus erythematosus in an egyptian population
inferred← citeshttps://doi.org/10.3389/fgene.2022.989639openalex-snapshot
Polygenic power calculator: Statistical power and polygenic prediction accuracy of genome-wide association studies of complex traits
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1111723openalex-snapshot
Integrative genetics-metabolomics analysis of infant bronchiolitis-childhood asthma link: A multicenter prospective study
inferred← citeshttps://doi.org/10.3389/fonc.2024.1475979openalex-snapshot
Association of the SNPs in CCL2 and CXCL12 genes with the susceptibility to breast cancer: a case-control study in China
inferred← citeshttps://doi.org/10.3389/fsysb.2022.1005758openalex-snapshot
Genome-wide association studies of viral infections—A short guide to a successful experimental and statistical analysis
inferred← citeshttps://doi.org/10.3390/genes14111995openalex-snapshot
Association between IRF6, TP63, GREM1 Gene Polymorphisms and Non-Syndromic Orofacial Cleft Phenotypes in Vietnamese Population: A Case–Control and Family-Based Study
inferred← citeshttps://doi.org/10.3390/ijms26083667openalex-snapshot
Association of MTNR1B Gene Polymorphisms with Body Mass Index in Hashimoto’s Thyroiditis
inferred← citeshttps://doi.org/10.3390/jcm13010249openalex-snapshot
Unraveling Catechol-O-Methyltransferase rs4680 SNP’s Role in Patients’ Response to Tramadol and Its Adverse Effects: A Pharmacogenetics Insight into Postoperative Pain Management
inferred← citeshttps://doi.org/10.3390/jpm10040184openalex-snapshot
Gender Differences in Genetic Associations of RAB38 with Urinary Protein-to-Creatinine Ratio (UPCR) Levels in Diabetic Nephropathy Patients
inferred← citeshttps://doi.org/10.3390/life11090886openalex-snapshot
The Link between Type 2 Diabetes Mellitus and the Polymorphisms of Glutathione-Metabolizing Genes Suggests a New Hypothesis Explaining Disease Initiation and Progression
inferred← citeshttps://doi.org/10.3390/life14091158openalex-snapshot
Obesity and Environmental Risk Factors Significantly Modify the Association between Ischemic Stroke and the Hero Chaperone C19orf53
inferred← citeshttps://doi.org/10.5334/tohm.885openalex-snapshot
Association Analysis of Essential Tremor-Associated Genetic Variants in Sporadic Late-Onset Parkinson’s Disease
inferred← citeshttps://doi.org/10.64898/2026.02.11.26345915openalex-snapshot
A meta-analysis of clinically ascertained lipoedema cohorts from the UK and Spain identifies overlapping susceptibility loci with the UK Biobank
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