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Synaptic accumulation of FUS triggers age-dependent misregulation of inhibitory synapses in ALS-FUS mice
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cne.903590111openalex-snapshot
GABA A ‐receptor heterogeneity in the adult rat brain: Differential regional and cellular distribution of seven major subunits
inferredcites →https://doi.org/10.1002/jcp.24395openalex-snapshot
FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress
inferredcites →https://doi.org/10.1007/s00018-015-1943-xopenalex-snapshot
The function of RNA-binding proteins at the synapse: implications for neurodegeneration
inferredcites →https://doi.org/10.1007/s00213-010-2142-yopenalex-snapshot
Contribution of GABAA receptors containing α3 subunits to the therapeutic-related and side effects of benzodiazepine-type drugs in monkeys
inferredcites →https://doi.org/10.1007/s00401-012-0984-6openalex-snapshot
Localization of fused in sarcoma (FUS) protein to the post-synaptic density in the brain
inferredcites →https://doi.org/10.1007/s00401-017-1797-4openalex-snapshot
Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1016/j.brainres.2018.02.011openalex-snapshot
Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD
inferredcites →https://doi.org/10.1016/j.brainresbull.2018.05.023openalex-snapshot
Driven to decay: Excitability and synaptic abnormalities in amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1016/j.cell.2006.05.049openalex-snapshot
Rules for Nuclear Localization Sequence Recognition by Karyopherinβ2
inferredcites →https://doi.org/10.1016/j.cell.2015.07.047openalex-snapshot
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
inferredcites →https://doi.org/10.1016/j.cell.2018.03.002openalex-snapshot
Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
inferredcites →https://doi.org/10.1016/j.cell.2018.03.003openalex-snapshot
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
inferredcites →https://doi.org/10.1016/j.cell.2018.03.004openalex-snapshot
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
inferredcites →https://doi.org/10.1016/j.cell.2018.03.056openalex-snapshot
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
inferredcites →https://doi.org/10.1016/j.celrep.2017.08.100openalex-snapshot
3′UTR Length-Dependent Control of SynGAP Isoform α2 mRNA by FUS and ELAV-like Proteins Promotes Dendritic Spine Maturation and Cognitive Function
inferredcites →https://doi.org/10.1016/j.celrep.2018.06.094openalex-snapshot
Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function
inferredcites →https://doi.org/10.1016/j.celrep.2020.02.026openalex-snapshot
Neuronal BIN1 Regulates Presynaptic Neurotransmitter Release and Memory Consolidation
inferredcites →https://doi.org/10.1016/j.conb.2019.02.008openalex-snapshot
Local translation in neuronal processes
inferredcites →https://doi.org/10.1016/j.cub.2005.01.058openalex-snapshot
The RNA Binding Protein TLS Is Translocated to Dendritic Spines by mGluR5 Activation and Regulates Spine Morphology
inferredcites →https://doi.org/10.1016/j.cub.2013.05.041openalex-snapshot
Interplay of Hippocampus and Prefrontal Cortex in Memory
inferredcites →https://doi.org/10.1016/j.molcel.2010.05.004openalex-snapshot
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
inferredcites →https://doi.org/10.1016/j.molcel.2018.11.012openalex-snapshot
The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity
inferredcites →https://doi.org/10.1016/j.neuron.2006.04.016openalex-snapshot
A Shared Vesicular Carrier Allows Synaptic Corelease of GABA and Glycine
inferredcites →https://doi.org/10.1016/j.neuron.2012.02.036openalex-snapshot
The Local Transcriptome in the Synaptic Neuropil Revealed by Deep Sequencing and High-Resolution Imaging
inferredcites →https://doi.org/10.1016/j.neuron.2013.03.009openalex-snapshot
Nanoscale Scaffolding Domains within the Postsynaptic Density Concentrate Synaptic AMPA Receptors
inferredcites →https://doi.org/10.1016/j.neuron.2013.05.013openalex-snapshot
Quantitative Nanoscopy of Inhibitory Synapses: Counting Gephyrin Molecules and Receptor Binding Sites
inferredcites →https://doi.org/10.1016/j.neuron.2015.10.030openalex-snapshot
ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function
inferredcites →https://doi.org/10.1016/j.neuron.2016.11.002openalex-snapshot
Life at Low Copy Number: How Dendrites Manage with So Few mRNAs
inferredcites →https://doi.org/10.1016/j.neuron.2018.07.007openalex-snapshot
Architecture of the Mouse Brain Synaptome
inferredcites →https://doi.org/10.1016/j.neuron.2018.09.044openalex-snapshot
ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS
inferredcites →https://doi.org/10.1016/j.neuron.2018.10.018openalex-snapshot
The AMPA Receptor Code of Synaptic Plasticity
inferredcites →https://doi.org/10.1016/j.neuropharm.2012.03.001openalex-snapshot
Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice
inferredcites →https://doi.org/10.1016/j.tins.2014.05.009openalex-snapshot
The multifunctional Staufen proteins: conserved roles from neurogenesis to synaptic plasticity
inferredcites →https://doi.org/10.1016/s0165-0173(97)00061-1openalex-snapshot
Salient features of synaptic organisation in the cerebral cortex1Published on the World Wide Web on 3 March 1998.1
inferredcites →https://doi.org/10.1016/s1474-4422(10)70195-2openalex-snapshot
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
inferredcites →https://doi.org/10.1038/72842openalex-snapshot
Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death
inferredcites →https://doi.org/10.1038/76615openalex-snapshot
Proteomic analysis of NMDA receptor–adhesion protein signaling complexes
inferredcites →https://doi.org/10.1038/emboj.2010.143openalex-snapshot
ALS‐associated fused in sarcoma (FUS) mutations disrupt Transportin‐mediated nuclear import
inferredcites →https://doi.org/10.1038/emm.2015.5openalex-snapshot
Gephyrin: a central GABAergic synapse organizer
inferredcites →https://doi.org/10.1038/ncomms8098openalex-snapshot
FUS regulates AMPA receptor function and FTLD/ALS-associated behaviour via GluA1 mRNA stabilization
inferredcites →https://doi.org/10.1038/nmeth.4197openalex-snapshot
Salmon provides fast and bias-aware quantification of transcript expression
inferredcites →https://doi.org/10.1038/nn.2779openalex-snapshot
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
inferredcites →https://doi.org/10.1038/nn.3230openalex-snapshot
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
inferredcites →https://doi.org/10.1038/nn.3514openalex-snapshot
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons
inferredcites →https://doi.org/10.1038/nsmb.2163openalex-snapshot
RNA targets of wild-type and mutant FET family proteins
inferredcites →https://doi.org/10.1038/nsmb.2699openalex-snapshot
Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges
inferredcites →https://doi.org/10.1038/s41594-019-0263-5openalex-snapshot
Local translation in neurons: visualization and function
inferredcites →https://doi.org/10.1038/s41598-017-01175-8openalex-snapshot
The tandem Agenet domain of fragile X mental retardation protein interacts with FUS
inferredcites →https://doi.org/10.1038/s41598-018-25007-5openalex-snapshot
Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1
inferredcites →https://doi.org/10.1038/s41598-019-42833-3openalex-snapshot
SNAP-25 isoforms differentially regulate synaptic transmission and long-term synaptic plasticity at central synapses
inferredcites →https://doi.org/10.1038/srep00529openalex-snapshot
Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions
inferredcites →https://doi.org/10.1038/srep00603openalex-snapshot
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
inferredcites →https://doi.org/10.1038/srep00960openalex-snapshot
Lithium storage mechanisms in purpurin based organic lithium ion battery electrodes
inferredcites →https://doi.org/10.1038/srep27935openalex-snapshot
Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice
inferredcites →https://doi.org/10.1042/bst0310865openalex-snapshot
Assembly of N-methyl-d-aspartate (NMDA) receptors
inferredcites →https://doi.org/10.1073/pnas.1715341114openalex-snapshot
Intersectin associates with synapsin and regulates its nanoscale localization and function
inferredcites →https://doi.org/10.1074/jbc.m111.291336openalex-snapshot
Molecular Basis of the γ-Aminobutyric Acid A Receptor α3 Subunit Interaction with the Clustering Protein Gephyrin
inferredcites →https://doi.org/10.1074/jbc.r112.386664openalex-snapshot
Structure, Function, and Modulation of GABAA Receptors
inferredcites →https://doi.org/10.1083/jcb.201302071openalex-snapshot
Local palmitoylation cycles define activity-regulated postsynaptic subdomains
inferredcites →https://doi.org/10.1093/bioinformatics/btq033openalex-snapshot
BEDTools: a flexible suite of utilities for comparing genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/bts635openalex-snapshot
STAR: ultrafast universal RNA-seq aligner
inferredcites →https://doi.org/10.1093/brain/awp214openalex-snapshot
A new subtype of frontotemporal lobar degeneration with FUS pathology
inferredcites →https://doi.org/10.1093/hmg/ddq137openalex-snapshot
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration
inferredcites →https://doi.org/10.1093/hmg/ddx415openalex-snapshot
Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUSWT transgenic mice
inferredcites →https://doi.org/10.1093/nar/gks042openalex-snapshot
Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation
inferredcites →https://doi.org/10.1093/nar/gkt835openalex-snapshot
PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage
inferredcites →https://doi.org/10.1101/gad.204602.112openalex-snapshot
FUS binds the CTD of RNA polymerase II and regulates its phosphorylation at Ser2
inferredcites →https://doi.org/10.1101/gad.255737.114openalex-snapshot
Position-specific binding of FUS to nascent RNA regulates mRNA length
inferredcites →https://doi.org/10.1126/science.1074069openalex-snapshot
Alzheimer's Disease Is a Synaptic Failure
inferredcites →https://doi.org/10.1126/science.1165942openalex-snapshot
Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6
inferredcites →https://doi.org/10.1126/science.1166066openalex-snapshot
Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis
inferredcites →https://doi.org/10.1126/science.aar7366openalex-snapshot
RNA buffers the phase separation behavior of prion-like RNA binding proteins
inferredcites →https://doi.org/10.1126/science.aar7432openalex-snapshot
mRNA structure determines specificity of a polyQ-driven phase separation
inferredcites →https://doi.org/10.1126/science.aav2642openalex-snapshot
The forebrain synaptic transcriptome is organized by clocks but its proteome is driven by sleep
inferredcites →https://doi.org/10.1126/science.aav3617openalex-snapshot
Sleep-wake cycles drive daily dynamics of synaptic phosphorylation
inferredcites →https://doi.org/10.1128/mcb.00884-09openalex-snapshot
TLS Inhibits RNA Polymerase III Transcription
inferredcites →https://doi.org/10.1186/1471-2121-9-37openalex-snapshot
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response
inferredcites →https://doi.org/10.1186/gb-2010-11-2-r14openalex-snapshot
Gene ontology analysis for RNA-seq: accounting for selection bias
inferredcites →https://doi.org/10.1186/gb-2010-11-3-r25openalex-snapshot
A scaling normalization method for differential expression analysis of RNA-seq data
inferredcites →https://doi.org/10.1186/gb-2014-15-1-r11openalex-snapshot
dCLIP: a computational approach for comparative CLIP-seq analyses
inferredcites →https://doi.org/10.1186/s12859-017-1934-zopenalex-snapshot
ImageJ2: ImageJ for the next generation of scientific image data
inferredcites →https://doi.org/10.1186/s13024-016-0124-1openalex-snapshot
Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts
inferredcites →https://doi.org/10.1186/s40478-015-0202-6openalex-snapshot
FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1261/rna.037804.112openalex-snapshot
FUS regulates genes coding for RNA-binding proteins in neurons by binding to their highly conserved introns
inferredcites →https://doi.org/10.1371/journal.pcbi.1007664openalex-snapshot
Tximeta: Reference sequence checksums for provenance identification in RNA-seq
inferredcites →https://doi.org/10.1371/journal.pone.0004936openalex-snapshot
Transcriptome Analysis of Synaptoneurosomes Identifies Neuroplasticity Genes Overexpressed in Incipient Alzheimer's Disease
inferredcites →https://doi.org/10.1523/jneurosci.0937-07.2007openalex-snapshot
Dysregulated Metabotropic Glutamate Receptor-Dependent Translation of AMPA Receptor and Postsynaptic Density-95 mRNAs at Synapses in a Mouse Model of Fragile X Syndrome
inferredcites →https://doi.org/10.1523/jneurosci.1166-05.2005openalex-snapshot
Evidence for a Significant Role of α3-Containing GABAAReceptors in Mediating the Anxiolytic Effects of Benzodiazepines
inferredcites →https://doi.org/10.1523/jneurosci.18-23-09733.1998openalex-snapshot
The Vesicular GABA Transporter, VGAT, Localizes to Synaptic Vesicles in Sets of Glycinergic as Well as GABAergic Neurons
inferredcites →https://doi.org/10.1523/jneurosci.1866-06.2006openalex-snapshot
Expression and Function of SNAP-25 as a Universal SNARE Component in GABAergic Neurons
inferredcites →https://doi.org/10.1523/jneurosci.2001-11.2011openalex-snapshot
The Residence Time of GABAARs at Inhibitory Synapses Is Determined by Direct Binding of the Receptor α1 Subunit to Gephyrin
inferredcites →https://doi.org/10.1523/jneurosci.2381-12.2013openalex-snapshot
Super-Resolution Imaging Reveals That AMPA Receptors Inside Synapses Are Dynamically Organized in Nanodomains Regulated by PSD95
inferredcites →https://doi.org/10.15252/embj.201592559openalex-snapshot
Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss
inferredcites →https://doi.org/10.1534/g3.119.400185openalex-snapshot
ARMOR: An A utomated R eproducible MO dular Workflow for Preprocessing and Differential Analysis of R NA-seq Data
inferredcites →https://doi.org/10.3389/fncel.2015.00001openalex-snapshot
Disparate roles of zinc in chemical hypoxia-induced neuronal death
inferredcites →https://doi.org/10.3389/fncel.2015.00496openalex-snapshot
Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons
inferredcites →https://doi.org/10.3389/fncel.2019.00097openalex-snapshot
Proliferation and Differentiation in the Adult Subventricular Zone Are Not Affected by CSF1R Inhibition
inferredcites →https://doi.org/10.3389/fncel.2019.00256openalex-snapshot
Synaptic FUS Localization During Motoneuron Development and Its Accumulation in Human ALS Synapses
inferredcites →https://doi.org/10.3389/fnmol.2019.00152openalex-snapshot
Posttranscriptional Gene Regulation of the GABA Receptor to Control Neuronal Inhibition
inferredcites →https://doi.org/10.3389/fnmol.2019.00154openalex-snapshot
Molecular Specialization of GABAergic Synapses on the Soma and Axon in Cortical and Hippocampal Circuit Function and Dysfunction
inferredcites →https://doi.org/10.3390/cells9020313openalex-snapshot
Proteomic Analysis of Brain Region and Sex-Specific Synaptic Protein Expression in the Adult Mouse Brain
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/978-1-0716-1975-9_19openalex-snapshot
Identification of RNA–RBP Interactions in Subcellular Compartments by CLIP-Seq
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.09.014openalex-snapshot
Phase Separation and Neurodegenerative Diseases: A Disturbance in the Force
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