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Wnt/PCP-primed intestinal stem cells directly differentiate into enteroendocrine or Paneth cells

https://doi.org/10.1101/2020.08.12.247585

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

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FltpT2AiCre: A new knock-in mouse line for conditional gene targeting in distinct mono- and multiciliated tissues

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Continuous Clonal Labeling Reveals Small Numbers of Functional Stem Cells in Intestinal Crypts and Adenomas

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De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

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Single-Cell Analysis of Proxy Reporter Allele-Marked Epithelial Cells Establishes Intestinal Stem Cell Hierarchy

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Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types

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Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse

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Gene Ontology: tool for the unification of biology

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The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+4’ cell markers

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Notch signals control the fate of immature progenitor cells in the intestine

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Identification of stem cells in small intestine and colon by marker gene Lgr5

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Intestinal label-retaining cells are secretory precursors expressing Lgr5

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Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity

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Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging

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Single-cell messenger RNA sequencing reveals rare intestinal cell types

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Identification of proliferative and mature β-cells in the islets of Langerhans

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A single-cell survey of the small intestinal epithelium

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Spatial reconstruction of single-cell gene expression data

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Dll1+ secretory progenitor cells revert to stem cells upon crypt damage

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Massively parallel digital transcriptional profiling of single cells

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Bmi1 is expressed in vivo in intestinal stem cells

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Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny

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Diffusion pseudotime robustly reconstructs lineage branching

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Impact of islet architecture on β-cell heterogeneity, plasticity and function

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The complex world of WNT receptor signalling

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Tales from the crypt: new insights into intestinal stem cells

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Lineage tracing meets single-cell omics: opportunities and challenges

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Mouse Label-Retaining Cells Are Molecularly and Functionally Distinct From Reserve Intestinal Stem Cells

inferredcites →https://doi.org/10.1073/pnas.1013004108openalex-snapshot

Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells

inferredcites →https://doi.org/10.1073/pnas.1309342111openalex-snapshot

Shp2/MAPK signaling controls goblet/paneth cell fate decisions in the intestine

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Fast unfolding of communities in large networks

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Biomartr: genomic data retrieval with R

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limma powers differential expression analyses for RNA-sequencing and microarray studies

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KEGG as a reference resource for gene and protein annotation

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Expansion of the Gene Ontology knowledgebase and resources

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g:Profiler—a web server for functional interpretation of gene lists (2016 update)

inferredcites →https://doi.org/10.1098/rstb.1998.0246openalex-snapshot

Stem cells in gastrointestinal epithelium: numbers, characteristics and death

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Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation

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Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors

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Requirement of Math1 for Secretory Cell Lineage Commitment in the Mouse Intestine

inferredcites →https://doi.org/10.1126/science.1213214openalex-snapshot

Interconversion Between Intestinal Stem Cell Populations in Distinct Niches

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Lineage tracing on transcriptional landscapes links state to fate during differentiation

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SCANPY: large-scale single-cell gene expression data analysis

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PAGA: graph abstraction reconciles clustering with trajectory inference through a topology preserving map of single cells

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Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo

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UMAP: Uniform Manifold Approximation and Projection

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A Video Protocol of Retroviral Infection in Primary Intestinal Organoid Culture

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Flattop regulates basal body docking and positioning in mono- and multiciliated cells

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