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The SARS-CoV-2 Spike Harbours a Lipid Binding Pocket Which Modulates Stability of the Prefusion Trimer

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Notum deacylates Wnt proteins to suppress signalling activity
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Toremifene interacts with and destabilizes the Ebola virus glycoprotein
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Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains
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cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
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Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
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Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient
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Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
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Beyond Shielding: The Roles of Glycans in SARS-CoV-2 Spike Protein
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Coot : model-building tools for molecular graphics
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Crystal structure of the post-fusion core of theHuman coronavirus 229Espike protein at 1.86 Å resolution
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Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
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A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
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Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
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Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
inferredcites →https://doi.org/10.1126/science.abb9983openalex-snapshot
Site-specific glycan analysis of the SARS-CoV-2 spike
inferredcites →https://doi.org/10.1126/science.abc1560openalex-snapshot
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
inferredcites →https://doi.org/10.1126/science.abc2241openalex-snapshot
A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2
inferredcites →https://doi.org/10.1126/science.abd4251openalex-snapshot
Distinct conformational states of SARS-CoV-2 spike protein
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Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity
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asarnow/pyem: UCSF pyem v0.5
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New tools for automated high-resolution cryo-EM structure determination in RELION-3
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Author response: New tools for automated high-resolution cryo-EM structure determination in RELION-3

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Diamond Light Source: contributions to SARS-CoV-2 biology and therapeutics
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The antigenic anatomy of SARS-CoV-2 receptor binding domain
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SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses
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Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies
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Multifaceted membrane binding head of the SARS-CoV-2 spike protein
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Progressive membrane-binding mechanism of SARS-CoV-2 variant spike proteins
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Coronavirus disease 2019 (COVID-19): Biophysical and biochemical aspects of SARS-CoV-2 and general characteristics
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Uncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein
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Molecular insights into species-specific ACE2 recognition of coronavirus HKU5
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Binding behavior of spike protein and receptor binding domain of the SARS-CoV-2 virus at different environmental conditions
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Lipid bilayer degradation induced by SARS-CoV-2 spike protein as revealed by neutron reflectometry
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Accelerating Inhibitor Discovery for Multiple SARS-CoV-2 Targets with a Single, Sequence-Guided Deep Generative Framework
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The Increased Amyloidogenicity of Spike RBD and pH-Dependent Binding to ACE2 May Contribute to the Transmissibility and Pathogenic Properties of SARS-CoV-2 Omicron as Suggested by In Silico Study
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The Binding of Brazilin from C. sappan to the Full-Length SARS-CoV-2 Spike Proteins
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SARS-CoV-2 Omicron Subvariants Balance Host Cell Membrane, Receptor, and Antibody Docking via an Overlapping Target Site
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