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The Impact of Pf Bacteriophages on the Fitness of Pseudomonas aeruginosa ; A Mathematical Modeling Approach

https://doi.org/10.1101/2020.08.30.272203

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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The changing epidemiology of cystic fibrosis

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Antibiotic resistance of bacterial biofilms

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Effectiveness of a stepwise Pseudomonas aeruginosa eradication protocol in children with cystic fibrosis

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ECFS best practice guidelines: the 2018 revision

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Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment

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Prevalence of Pf1-like (pro)phage genetic elements among Pseudomonas aeruginosa isolates

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Filamentous bacteriophage delays healing of Pseudomonas-infected wounds

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The quantitative distribution of nebulized antibiotic in the lung in cystic fibrosis

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99 Pf bacteriophage (Pf) in Pseudomonas aeruginosa (Pa) biofilms is associated with increased elastase in the sputum of patients with cystic fibrosis (CF)

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Gene expression in Pseudomonas aeruginosa biofilms

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The biofilm life cycle and virulence of Pseudomonas aeruginosa are dependent on a filamentous prophage

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Cryptic inoviruses revealed as pervasive in bacteria and archaea across Earth’s biomes

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Intermittent Administration of Inhaled Tobramycin in Patients with Cystic Fibrosis

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Clinical outcome after early Pseudomonas aeruginosa infection in cystic fibrosis

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Statistical structure of host–phage interactions

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Phage liquid crystalline droplets form occlusive sheaths that encapsulate and protect infectious rod-shaped bacteria

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Aerosol Deposition in Health and Disease

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Sputum Tobramycin Concentrations in Cystic Fibrosis Patients with Repeated Administration of Inhaled Tobramycin

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Susceptibility of bacterial biofilms to tobramycin: role of specific growth rate and phase in the division cycle

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Biofilm penetration, triggered release and in vivo activity of inhaled liposomal amikacin in chronic Pseudomonas aeruginosa lung infections

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Functional relationship between bacterial cell density and the efficacy of antibiotics

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Complete nucleotide sequence of filamentous phage Cf1c fromXanthomonas campestrispv.citri

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Pf4 bacteriophage produced by Pseudomonas aeruginosa inhibits Aspergillus fumigatus metabolism via iron sequestration

inferredcites →https://doi.org/10.1111/1758-2229.12388openalex-snapshot

Filamentous phage SW1 is active and influences the transcriptome of the host at high‐pressure and low‐temperature

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The role of bacterial biofilms in chronic infections

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Ligand binding assays at equilibrium: validation and interpretation

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Delayed wound healing in diabetic (db/db) mice with Pseudomonas aeruginosa biofilm challenge: a model for the study of chronic wounds

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Bacterial antagonism in host-associated microbial communities

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Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection

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Filamentous bacteriophages are associated with chronic Pseudomonas lung infections and antibiotic resistance in cystic fibrosis

inferredcites →https://doi.org/10.1126/scitranslmed.aaw8434openalex-snapshot

Selective activation of TWIK-related acid-sensitive K + 3 subunit–containing channels is analgesic in rodent models

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Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms

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Bactericidal effects of antibiotics on slowly growing and nongrowing bacteria

inferredcites →https://doi.org/10.1128/aac.42.7.1641openalex-snapshot

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inferredcites →https://doi.org/10.1128/aac.48.10.3670-3676.2004openalex-snapshot

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Cystic Fibrosis Pulmonary Guidelines

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Early Respiratory Infection is Associated with Reduced Spirometry in Children with Cystic Fibrosis

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Biofilm assembly becomes crystal clear – filamentous bacteriophage organize the Pseudomonas aeruginosa biofilm matrix into a liquid crystal

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inferredcites →https://doi.org/10.3389/fimmu.2020.00244openalex-snapshot

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inferredcites →https://doi.org/10.3390/pharmaceutics11090470openalex-snapshot

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Understanding Bacteriophage Specificity in Natural Microbial Communities

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The clinical impact of bacterial biofilms

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1101/2021.12.03.471163openalex-snapshot

Modelling of filamentous phage-induced antibiotic tolerance of P.aeruginosa

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