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Losartan promotes cell survival following SARS-CoV-2 infection in vitro

https://doi.org/10.1101/2020.12.27.424507

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing

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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): An overview of viral structure and host response

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Impact of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers on COVID-19 in a western population. CARDIOVID registry

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Characterization and Noncovalent Inhibition of the Deubiquitinase and deISGylase Activity of SARS-CoV-2 Papain-Like Protease

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Proton Transfer Properties of Imidazole

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Antithrombotic effects of losartan in patients with hypertension complicated by atrial fibrillation: 4A (Angiotensin II Antagonist of platelet Aggregation in patients with Atrial fibrillation), a pilot study

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Losartan attenuates the coronary perivasculitis through its local and systemic anti-inflammatory properties in a murine model of Kawasaki disease

inferredcites →https://doi.org/10.1038/s41392-020-00332-2openalex-snapshot

Main protease of SARS-CoV-2 serves as a bifunctional molecule in restricting type I interferon antiviral signaling

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Tumor-induced neurogenesis and immune evasion as targets of innovative anti-cancer therapies

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SARS-CoV-2 downregulation of ACE2 and pleiotropic effects of ACEIs/ARBs

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Trade-offs between multifunctionality and profit in tropical smallholder landscapes

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Activation and evasion of type I interferon responses by SARS-CoV-2

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COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system

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Therapeutically administered ribonucleoside analogue MK-4482/EIDD-2801 blocks SARS-CoV-2 transmission in ferrets

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Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses

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Murine Coronavirus Ubiquitin-Like Domain Is Important for Papain-Like Protease Stability and Viral Pathogenesis

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Alpha/Beta Interferon (IFN-α/β)-Independent Induction of IFN-λ1 (Interleukin-29) in Response to Hantaan Virus Infection

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Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF-κB Signaling

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Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases

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The Papain-Like Protease from the Severe Acute Respiratory Syndrome Coronavirus Is a Deubiquitinating Enzyme

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Response to the emerging novel coronavirus outbreak

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Ubiquitination and de-ubiquitination: role in regulation of signaling by Toll-like receptors

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Intracellular superoxide and hydrogen peroxide concentrations: a critical balance that determines survival or death

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The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity

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Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling

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Identification of Host Kinase Genes Required for Influenza Virus Replication and the Regulatory Role of MicroRNAs

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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies

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Probing the impact of nairovirus genomic diversity on viral ovarian tumor domain protease (vOTU) structure and deubiquitinase activity

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SARS Virus Papain-Like Protease: A Mysterious Weapon

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Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States

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Severe Acute Respiratory Syndrome Coronavirus 2: From Gene Structure to Pathogenic Mechanisms and Potential Therapy

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SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6

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The COVID-19 Pandemic: A Comprehensive Review of Taxonomy, Genetics, Epidemiology, Diagnosis, Treatment, and Control

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Vero Cells as a Mammalian Cell Substrate for Human Norovirus

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[Inhibitors of RAS Might Be a Good Choice for the Therapy of COVID-19 Pneumonia].

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2174/0115701638279362240223070810openalex-snapshot

In silico Evaluation of NO-Sartans against SARS-CoV-2

inferred← citeshttps://doi.org/10.55175/cdk.v49i2.200openalex-snapshot

Potensi Candesartan dalam Terapi COVID 19

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