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The MEK-ERK signaling pathway promotes maintenance of cardiac chamber identity
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Germ‐line transmission of a myocardium‐specific GFP transgene reveals critical regulatory elements in the cardiac myosin light chain 2 promoter of zebrafish
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The Tol2kit: A multisite gateway‐based construction kit for Tol2 transposon transgenesis constructs
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Exposure to the JNK inhibitor SP600125 (anthrapyrazolone) during early zebrafish development results in morphological defects
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Primitive-Streak Origin of the Cardiovascular System in Avian Embryos
inferredcites →https://doi.org/10.1006/dbio.1999.9406openalex-snapshot
Restricted Expression of Cardiac Myosin Genes Reveals Regulated Aspects of Heart Tube Assembly in Zebrafish
inferredcites →https://doi.org/10.1006/dbio.1999.9548openalex-snapshot
Cardiac Expression of the Ventricle-Specific Homeobox Gene Irx4 Is Modulated by Nkx2-5 and dHand
inferredcites →https://doi.org/10.1006/dbio.2000.9753openalex-snapshot
Chamber Formation and Morphogenesis in the Developing Mammalian Heart
inferredcites →https://doi.org/10.1006/dbio.2001.0259openalex-snapshot
Bmp2b and Oep Promote Early Myocardial Differentiation through Their Regulation of gata5
inferredcites →https://doi.org/10.1007/978-1-60327-977-2_8openalex-snapshot
Simple and Efficient Transgenesis with Meganuclease Constructs in Zebrafish
inferredcites →https://doi.org/10.1007/s00018-016-2297-8openalex-snapshot
Negative feedback regulation of the ERK1/2 MAPK pathway
inferredcites →https://doi.org/10.1016/0012-1606(70)90163-6openalex-snapshot
Location and movements of cardiogenic cells in the chick embryo: The heart-forming portion of the primitive streak
inferredcites →https://doi.org/10.1016/j.addr.2019.12.002openalex-snapshot
Towards chamber specific heart-on-a-chip for drug testing applications
inferredcites →https://doi.org/10.1016/j.bbamcr.2012.10.004openalex-snapshot
Evolution and development of the building plan of the vertebrate heart
inferredcites →https://doi.org/10.1016/j.cell.2018.11.042openalex-snapshot
A Platform for Generation of Chamber-Specific Cardiac Tissues and Disease Modeling
inferredcites →https://doi.org/10.1016/j.cytogfr.2005.01.007openalex-snapshot
Mechanisms underlying differential responses to FGF signaling
inferredcites →https://doi.org/10.1016/j.devcel.2013.04.017openalex-snapshot
Atrial Identity Is Determined by a COUP-TFII Regulatory Network
inferredcites →https://doi.org/10.1016/j.devcel.2016.10.001openalex-snapshot
Single-Cell Resolution of Temporal Gene Expression during Heart Development
inferredcites →https://doi.org/10.1016/j.devcel.2016.10.014openalex-snapshot
Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells
inferredcites →https://doi.org/10.1016/j.devcel.2020.09.030openalex-snapshot
Live Visualization of ERK Activity in the Mouse Blastocyst Reveals Lineage-Specific Signaling Dynamics
inferredcites →https://doi.org/10.1016/j.isci.2021.103386openalex-snapshot
Noncanonical protease-activated receptor 1 regulates lymphatic differentiation in zebrafish
inferredcites →https://doi.org/10.1016/j.stem.2017.07.003openalex-snapshot
Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
inferredcites →https://doi.org/10.1016/j.stem.2019.07.010openalex-snapshot
Human Pluripotent Stem Cell-Derived Cardiovascular Cells: From Developmental Biology to Therapeutic Applications
inferredcites →https://doi.org/10.1016/j.ydbio.2005.09.011openalex-snapshot
Functions and regulations of fibroblast growth factor signaling during embryonic development
inferredcites →https://doi.org/10.1016/j.ydbio.2008.06.033openalex-snapshot
Reiterative roles for FGF signaling in the establishment of size and proportion of the zebrafish heart
inferredcites →https://doi.org/10.1016/j.ydbio.2009.02.010openalex-snapshot
Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionality
inferredcites →https://doi.org/10.1016/j.ydbio.2009.02.031openalex-snapshot
A genetic screen for vascular mutants in zebrafish reveals dynamic roles for Vegf/Plcg1 signaling during artery development
inferredcites →https://doi.org/10.1016/j.ydbio.2009.09.012openalex-snapshot
Neural ectoderm-secreted FGF initiates the expression of Nkx2.5 in cardiac progenitors via a p38 MAPK/CREB pathway
inferredcites →https://doi.org/10.1016/j.ydbio.2010.03.011openalex-snapshot
Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development
inferredcites →https://doi.org/10.1016/j.ydbio.2011.03.028openalex-snapshot
Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafish
inferredcites →https://doi.org/10.1016/j.ydbio.2013.09.023openalex-snapshot
FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst
inferredcites →https://doi.org/10.1016/j.ydbio.2014.12.019openalex-snapshot
An early requirement for nkx2.5 ensures the first and second heart field ventricular identity and cardiac function into adulthood
inferredcites →https://doi.org/10.1038/nature10094openalex-snapshot
Latent TGF-β binding protein 3 identifies a second heart field in zebrafish
inferredcites →https://doi.org/10.1038/nrm1400openalex-snapshot
Modulation of signalling by Sprouty: a developing story
inferredcites →https://doi.org/10.1038/s41467-016-0009-6openalex-snapshot
In situ click chemistry generation of cyclooxygenase-2 inhibitors
inferredcites →https://doi.org/10.1038/s41467-018-02974-xopenalex-snapshot
No evidence that carotenoid pigments boost either immune or antioxidant defenses in a songbird
inferredcites →https://doi.org/10.1038/s41467-019-13868-xopenalex-snapshot
Generating ring-shaped engineered heart tissues from ventricular and atrial human pluripotent stem cell-derived cardiomyocytes
inferredcites →https://doi.org/10.1038/s41467-021-25329-5openalex-snapshot
Self-assembling human heart organoids for the modeling of cardiac development and congenital heart disease
inferredcites →https://doi.org/10.1038/s41551-022-00885-3openalex-snapshot
Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances
inferredcites →https://doi.org/10.1038/s41586-020-03085-8openalex-snapshot
Control of osteoblast regeneration by a train of Erk activity waves
inferredcites →https://doi.org/10.1038/s44161-023-00334-7openalex-snapshot
Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network
inferredcites →https://doi.org/10.1073/pnas.0502933102openalex-snapshot
Control of the segmentation process by graded MAPK/ERK activation in the chick embryo
inferredcites →https://doi.org/10.1073/pnas.0702447104openalex-snapshot
Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function
inferredcites →https://doi.org/10.1091/mbc.e18-05-0295openalex-snapshot
Cellular crowding influences extrusion and proliferation to facilitate epithelial tissue repair
inferredcites →https://doi.org/10.1101/gad.1083503openalex-snapshot
Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis
inferredcites →https://doi.org/10.1101/gad.1629408openalex-snapshot
Foxn4 directly regulates tbx2b expression and atrioventricular canal formation
inferredcites →https://doi.org/10.1101/gad.2035311openalex-snapshot
Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis
inferredcites →https://doi.org/10.1101/gad.222902openalex-snapshot
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation
inferredcites →https://doi.org/10.1101/gad.277137.115openalex-snapshot
Genetic insights into the mechanisms of Fgf signaling
inferredcites →https://doi.org/10.1126/science.283.5405.1161openalex-snapshot
Regulation of Chamber-Specific Gene Expression in the Developing Heart by Irx4
inferredcites →https://doi.org/10.1128/iai.00604-10openalex-snapshot
Constitutive MEK1 Activation Rescues Anthrax Lethal Toxin-Induced Vascular Effects In Vivo
inferredcites →https://doi.org/10.1128/mcb.21.5.1730-1736.2001openalex-snapshot
Cardiomyopathy in Irx4-Deficient Mice Is Preceded by Abnormal Ventricular Gene Expression
inferredcites →https://doi.org/10.1146/annurev-genet-110711-155646openalex-snapshot
Uncovering the Molecular and Cellular Mechanisms of Heart Development Using the Zebrafish
inferredcites →https://doi.org/10.1152/ajpcell.00402.2009openalex-snapshot
Differential gene expressions in atrial and ventricular myocytes: insights into the road of applying embryonic stem cell-derived cardiomyocytes for future therapies
inferredcites →https://doi.org/10.1152/physiolgenomics.00033.2003openalex-snapshot
Developmental anatomy of the heart: a tale of mice and man
inferredcites →https://doi.org/10.1152/physiolgenomics.00137.2011openalex-snapshot
Comparison of human cardiac gene expression profiles in paired samples of right atrium and left ventricle collected in vivo
inferredcites →https://doi.org/10.1152/physrev.00006.2003openalex-snapshot
Cardiac Chamber Formation: Development, Genes, and Evolution
inferredcites →https://doi.org/10.1158/1078-0432.ccr-08-0333openalex-snapshot
Advances in the Development of Cancer Therapeutics Directed against the RAS-Mitogen-Activated Protein Kinase Pathway
inferredcites →https://doi.org/10.1161/01.res.0000261693.13269.bfopenalex-snapshot
CHF1/Hey2 Plays a Pivotal Role in Left Ventricular Maturation Through Suppression of Ectopic Atrial Gene Expression
inferredcites →https://doi.org/10.1161/cir.0000000000000606openalex-snapshot
Genetic Basis for Congenital Heart Disease: Revisited: A Scientific Statement From the American Heart Association
inferredcites →https://doi.org/10.1172/jci.insight.99941openalex-snapshot
Deep phenotyping of human induced pluripotent stem cell–derived atrial and ventricular cardiomyocytes
inferredcites →https://doi.org/10.1186/1471-213x-7-1openalex-snapshot
Multiple upstream modules regulate zebrafish myf5expression
inferredcites →https://doi.org/10.1186/s12929-015-0138-yopenalex-snapshot
“Down syndrome: an insight of the disease”
inferredcites →https://doi.org/10.1210/en.2012-1555openalex-snapshot
GnRH Neuronal Migration and Olfactory Bulb Neurite Outgrowth Are Dependent on FGF Receptor 1 Signaling, Specifically via the PI3K p110α Isoform in Chick Embryo
inferredcites →https://doi.org/10.1242/dev.00838openalex-snapshot
Mutation of weak atrium/atrial myosin heavy chain disrupts atrial function and influences ventricular morphogenesis in zebrafish
inferredcites →https://doi.org/10.1242/dev.01185openalex-snapshot
Organization of cardiac chamber progenitors in the zebrafish blastula
inferredcites →https://doi.org/10.1242/dev.030924openalex-snapshot
Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart
inferredcites →https://doi.org/10.1242/dev.038893openalex-snapshot
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
inferredcites →https://doi.org/10.1242/dev.061473openalex-snapshot
Zebrafish cardiac development requires a conserved secondary heart field
inferredcites →https://doi.org/10.1242/dev.084996openalex-snapshot
FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse
inferredcites →https://doi.org/10.1242/dev.095562openalex-snapshot
Nkx genes are essential for maintenance of ventricular identity
inferredcites →https://doi.org/10.1242/dev.098905openalex-snapshot
An anterior limit of FGF/Erk signal activity marks the earliest future somite boundary in zebrafish
inferredcites →https://doi.org/10.1242/dev.119.1.31openalex-snapshot
Cardiovascular development in the zebrafish I. Myocardial fate map and heart tube formation
inferredcites →https://doi.org/10.1242/dev.124883openalex-snapshot
The formation and function of the cardiac conduction system
inferredcites →https://doi.org/10.1242/dev.127.2.225openalex-snapshot
Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar)
inferredcites →https://doi.org/10.1242/dev.137919openalex-snapshot
Vegfa signals through ERK to promote angiogenesis, but not artery differentiation
inferredcites →https://doi.org/10.1242/dev.143719openalex-snapshot
FGF signaling enforces cardiac chamber identity in the developing ventricle
inferredcites →https://doi.org/10.1242/jcs.057646openalex-snapshot
Crucial role of phosphatidylinositol 4-kinase IIIα in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling
inferredcites →https://doi.org/10.1371/journal.pbio.0050053openalex-snapshot
Functional Modulation of Cardiac Form through Regionally Confined Cell Shape Changes
inferredcites →https://doi.org/10.1371/journal.pbio.3001200openalex-snapshot
Ventricular, atrial, and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streak
inferredcites →https://doi.org/10.1371/journal.pgen.1009744openalex-snapshot
The Integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila
inferredcites →https://doi.org/10.1371/journal.pone.0147823openalex-snapshot
Chamber Specific Gene Expression Landscape of the Zebrafish Heart
inferredcites →https://doi.org/10.1387/ijdb.180408asopenalex-snapshot
FGF/ERK signaling pathway: how it operates in mammalian preimplantation embryos and embryo-derived stem cells
inferredcites →https://doi.org/10.3389/fcell.2021.655161openalex-snapshot
Human Pluripotent Stem Cell-Derived Cardiac Cells: Application in Disease Modeling, Cell Therapy, and Drug Discovery
inferredcites →https://doi.org/10.3390/cells10061342openalex-snapshot
Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
inferredcites →https://doi.org/10.3390/ijms21124354openalex-snapshot
Modeling Cardiac Disease Mechanisms Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Progress, Promises and Challenges
inferredcites →https://doi.org/10.3390/jcdd8020013openalex-snapshot
Pathways Regulating Establishment and Maintenance of Cardiac Chamber Identity in Zebrafish
inferredcites →https://doi.org/10.3390/jcdd8020015openalex-snapshot
Atrial and Sinoatrial Node Development in the Zebrafish Heart
inferredcites →https://doi.org/10.7554/elife.73231openalex-snapshot
Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish
inferredcites →https://doi.org/10.7554/elife.77408openalex-snapshot
Nr2f1a maintains atrial nkx2.5 expression to repress pacemaker identity within venous atrial cardiomyocytes of zebrafish
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