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Vincristine treatment reverses podocyte damage in focal segmental glomerulosclerosis

https://doi.org/10.1101/2024.11.13.623397

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Increasing the dosage of vincristine

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Anlotinib, Vincristine, and Irinotecan for Advanced Ewing Sarcoma After Failure of Standard Multimodal Therapy: A Two-Cohort, Phase Ib/II Trial

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Generation of a Glomerular Filtration Barrier on a Glomerulus-on-a-Chip Platform

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Vincristine treatment of nephrotic syndrome complicated by Kimura disease

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Vincristine treatment in steroid-dependent nephrotic syndrome

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TNFα pathway blockade ameliorates toxic effects of FSGS plasma on podocyte cytoskeleton and β3 integrin activation

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Serum suPAR in patients with FSGS: trash or treasure?

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Vincristine and focal segmental sclerosis: do we need a multicentre trial?

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Upregulation of podocyte-secreted angiopoietin-like-4 in diabetic nephropathy

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The binding of vincristine, vinblastine and colchicine to tubulin

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Lnc-FAM84B-4 acts as an oncogenic lncRNA by interacting with protein hnRNPK to restrain MAPK phosphatases-DUSP1 expression

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Actin-Network Architecture Regulates Microtubule Dynamics

inferredcites →https://doi.org/10.1016/j.ekir.2022.09.014openalex-snapshot

Circulating Permeability Factors in Focal Segmental Glomerulosclerosis: In Vitro Detection

inferredcites →https://doi.org/10.1016/j.kint.2024.07.022openalex-snapshot

Pre-transplant anti-nephrin antibodies are specific predictors of recurrent diffuse podocytopathy in the kidney allograft

inferredcites →https://doi.org/10.1016/j.ymthe.2023.09.003openalex-snapshot

Asparagine endopeptidase protects podocytes in adriamycin-induced nephropathy by regulating actin dynamics through cleaving transgelin

inferredcites →https://doi.org/10.1016/s0140-6736(20)30045-3openalex-snapshot

Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

inferredcites →https://doi.org/10.1038/200484a0openalex-snapshot

Suppression of Immune Response by ‘Vincristine’ and ‘Vinblastine’

inferredcites →https://doi.org/10.1038/nbt0816-888dopenalex-snapshot

Erratum: Near-optimal probabilistic RNA-seq quantification

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Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome

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Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models

inferredcites →https://doi.org/10.1038/nrneph.2011.151openalex-snapshot

The podocyte cytoskeleton—key to a functioning glomerulus in health and disease

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Progress in MS—classification, mechanisms and treatment

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Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system

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A glomerulus-on-a-chip to recapitulate the human glomerular filtration barrier

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A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain

inferredcites →https://doi.org/10.1038/s41598-022-16287-zopenalex-snapshot

Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice

inferredcites →https://doi.org/10.1056/nejmoa2314471openalex-snapshot

Autoantibodies Targeting Nephrin in Podocytopathies

inferredcites →https://doi.org/10.1074/jbc.m117.788463openalex-snapshot

Regulation of mitochondrial protein import by the nucleotide exchange factors GrpEL1 and GrpEL2 in human cells

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Branched actin networks are assembled on microtubules by adenomatous polyposis coli for targeted membrane protrusion

inferredcites →https://doi.org/10.1083/jcb.202404112openalex-snapshot

Profilin affects microtubule dynamics via actin

inferredcites →https://doi.org/10.1091/mbc.e16-10-0733openalex-snapshot

Coupled excitable Ras and F-actin activation mediates spontaneous pseudopod formation and directed cell movement

inferredcites →https://doi.org/10.1091/mbc.e19-09-0491openalex-snapshot

New twists in actin–microtubule interactions

inferredcites →https://doi.org/10.1093/ckj/sfad193openalex-snapshot

Genetic testing in focal segmental glomerulosclerosis: in whom and when?

inferredcites →https://doi.org/10.1093/ndt/gfw021openalex-snapshot

Targeting the podocyte cytoskeleton: from pathogenesis to therapy in proteinuric kidney disease

inferredcites →https://doi.org/10.1128/mcb.12.2.791openalex-snapshot

Physical evidence for cotranslational regulation of beta-tubulin mRNA degradation.

inferredcites →https://doi.org/10.1152/ajprenal.00641.2017openalex-snapshot

Mechanical challenges and cytoskeletal impairments in focal segmental glomerulosclerosis

inferredcites →https://doi.org/10.1155/2017/1757940openalex-snapshot

Pulsed Vincristine Therapy in Steroid-Resistant Nephrotic Syndrome

inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

inferredcites →https://doi.org/10.1186/s13578-017-0153-7openalex-snapshot

Control of gene expression through the nonsense-mediated RNA decay pathway

inferredcites →https://doi.org/10.1242/jcs.252916openalex-snapshot

Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones

inferredcites →https://doi.org/10.12688/f1000research.7563.1openalex-snapshot

Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences

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Tubulin mRNA stability is sensitive to change in microtubule dynamics caused by multiple physiological and toxic cues

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The Calcineurin Inhibitor Tacrolimus Reduces Proteinuria in Membranous Nephropathy Accompanied by a Decrease in Angiopoietin-Like-4

inferredcites →https://doi.org/10.1681/asn.2013111213openalex-snapshot

Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease

inferredcites →https://doi.org/10.1681/asn.2016010008openalex-snapshot

Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation

inferredcites →https://doi.org/10.1681/asn.2017020143openalex-snapshot

The Evolving Complexity of the Podocyte Cytoskeleton

inferredcites →https://doi.org/10.1681/asn.2017050475openalex-snapshot

Similar Biophysical Abnormalities in Glomeruli and Podocytes from Two Distinct Models

inferredcites →https://doi.org/10.1681/asn.2017121338openalex-snapshot

The Human FSGS-Causing ANLN R431C Mutation Induces Dysregulated PI3K/AKT/mTOR/Rac1 Signaling in Podocytes

inferredcites →https://doi.org/10.1681/asn.v133630openalex-snapshot

A Conditionally Immortalized Human Podocyte Cell Line Demonstrating Nephrin and Podocin Expression

inferredcites →https://doi.org/10.2215/cjn.05960616openalex-snapshot

Focal Segmental Glomerulosclerosis

inferredcites →https://doi.org/10.3389/fimmu.2023.1247606openalex-snapshot

Current understanding of the molecular mechanisms of circulating permeability factor in focal segmental glomerulosclerosis

inferredcites →https://doi.org/10.3389/fphys.2021.599529openalex-snapshot

The Biological Significance and Implications of Planar Cell Polarity for Nephrology

inferredcites →https://doi.org/10.3390/ijms21020392openalex-snapshot

Effect of F-actin and Microtubules on Cellular Mechanical Behavior Studied Using Atomic Force Microscope and an Image Recognition-Based Cytoskeleton Quantification Approach

inferredcites →https://doi.org/10.3390/ijms25010647openalex-snapshot

Cytoskeleton Rearrangement in Podocytopathies: An Update

inferredcites →https://doi.org/10.3892/ijmm.16.1.49openalex-snapshot

Direct effect of plasma permeability factors from patients with idiopatic FSGS on nephrin and podocin expression in human podocytes

inferredcites →https://doi.org/10.3892/ijo.25.2.407openalex-snapshot

The immunosuppressive effect of vincristine on allostimulatory potential of human dendritic cells interferes with their function and survival

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