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A microbiome-derived nutrient underlies tyrosine metabolism and predator avoidance in mosquito larvae

https://doi.org/10.1101/2025.04.02.646203
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Effects of a Diet Deficient in Tyrosine and Queuine on Germfree Mice
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Tyrosine Metabolism for Insect Cuticle Pigmentation and Sclerotization
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Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth
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A Gut Commensal Bacterium Promotes Mosquito Permissiveness to Arboviruses
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Abundances of transfer RNA modifications and transcriptional levels for tRNA-modifying enzymes are sex-specific in mosquitoes
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Dopamine levels in the mosquito Aedes aegypti during adult development, following blood feeding and in response to heat stress
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Queuine: A Bacterial Nucleobase Shaping Translation in Eukaryotes
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Administration of exogenous queuine is essential for the biosynthesis of the queuosine-containing transfer RNAs in the mouse.
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Identification of a Novel Epoxyqueuosine Reductase Family by Comparative Genomics
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A new function of S-adenosylmethionine: The ribosyl moiety of AdoMet is the precursor of the cyclopentenediol moiety of the tRNA wobble base queuine
inferredcites →https://doi.org/10.1023/a:1015279221600openalex-snapshot
Effects of Tyrosine Hydroxylase Mutants on Locomotor Activity in Drosophila: A Study in Functional Genomics
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Update on the Keio collection of Escherichia coli single‐gene deletion mutants
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Erratum: Near-optimal probabilistic RNA-seq quantification
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Dehydration prompts increased activity and blood feeding by mosquitoes
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The environment and species affect gut bacteria composition in laboratory co-cultured Anopheles gambiae and Aedes albopictus mosquitoes
inferredcites →https://doi.org/10.1073/pnas.1909604116openalex-snapshot
Discovery of novel bacterial queuine salvage enzymes and pathways in human pathogens
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Riboflavin instability is a key factor underlying the requirement of a gut microbiota for mosquito development
inferredcites →https://doi.org/10.1074/jbc.m111.219576openalex-snapshot
Queuosine Deficiency in Eukaryotes Compromises Tyrosine Production through Increased Tetrahydrobiopterin Oxidation
inferredcites →https://doi.org/10.1080/03949370.2017.1313785openalex-snapshot
Playing it safe? Behavioural responses of mosquito larvae encountering a fish predator
inferredcites →https://doi.org/10.1080/10253890500147381openalex-snapshot
Stress affects dopaminergic signaling pathways inDrosophila melanogaster
inferredcites →https://doi.org/10.1080/15476286.2017.1356562openalex-snapshot
Celebrating wobble decoding: Half a century and still much is new
inferredcites →https://doi.org/10.1093/ee/nvaa101openalex-snapshot
Antipredatory Responses of Mosquito Pupae to Non-Lethal Predation Threat—Behavioral Plasticity Across Life-History Stages
inferredcites →https://doi.org/10.1093/jme/tjab184openalex-snapshot
Bacterial Communities of Lab and Field Northern House Mosquitoes (Diptera: Culicidae) Throughout Diapause
inferredcites →https://doi.org/10.1093/nar/gkab1204openalex-snapshot
Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei
inferredcites →https://doi.org/10.1093/nar/gkad667openalex-snapshot
tRNA queuosine modification is involved in biofilm formation and virulence in bacteria
inferredcites →https://doi.org/10.1093/nar/gkv980openalex-snapshot
Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine
inferredcites →https://doi.org/10.1093/nar/gkz063openalex-snapshot
Queuine links translational control in eukaryotes to a micronutrient from bacteria
inferredcites →https://doi.org/10.1093/procel/pwad021openalex-snapshot
Impact of the microbiome on mosquito-borne diseases
inferredcites →https://doi.org/10.1101/gr.272153.120openalex-snapshot
Tissue-specific reprogramming of host tRNA transcriptome by the microbiome
inferredcites →https://doi.org/10.1111/imb.12950openalex-snapshot
Tyrosine transfer RNA levels and modifications during blood‐feeding and vitellogenesis in the mosquito, Aedes aegypti
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Deep sequencing reveals extensive variation in the gut microbiota of wild mosquitoes from K enya
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Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
inferredcites →https://doi.org/10.1111/mec.13877openalex-snapshot
Mosquitoes host communities of bacteria that are essential for development but vary greatly between local habitats
inferredcites →https://doi.org/10.1128/jb.173.7.2256-2264.1991openalex-snapshot
Structure and organization of Escherichia coli genes involved in biosynthesis of the deazaguanine derivative queuine, a nutrient factor for eukaryotes
inferredcites →https://doi.org/10.1128/msphere.00646-21openalex-snapshot
Host-Environment Interplay Shapes Fungal Diversity in Mosquitoes
inferredcites →https://doi.org/10.1186/1756-3305-4-105openalex-snapshot
Contribution of midgut bacteria to blood digestion and egg production in Aedes aegypti (diptera: culicidae) (L.)
inferredcites →https://doi.org/10.1186/s12864-023-09804-5openalex-snapshot
Exploring the molecular makeup of support cells in insect camera eyes
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1186/s40168-021-01073-2openalex-snapshot
The microbiome and mosquito vectorial capacity: rich potential for discovery and translation
inferredcites →https://doi.org/10.1186/s40168-022-01256-5openalex-snapshot
Interspecies microbiome transplantation recapitulates microbial acquisition in mosquitoes
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A Nutrient-Driven tRNA Modification Alters Translational Fidelity and Genome-wide Protein Coding across an Animal Genus
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Dopamine Is a Regulator of Arousal in the Fruit Fly
inferredcites →https://doi.org/10.15252/embj.2022112507openalex-snapshot
Queuosine‐tRNA promotes sex‐dependent learning and memory formation by maintaining codon‐biased translation elongation speed
inferredcites →https://doi.org/10.3389/fmicb.2021.630438openalex-snapshot
Mosquito Trilogy: Microbiota, Immunity and Pathogens, and Their Implications for the Control of Disease Transmission
inferredcites →https://doi.org/10.3390/biom7010014openalex-snapshot
Cross-Talk between Dnmt2-Dependent tRNA Methylation and Queuosine Modification
inferredcites →https://doi.org/10.3390/nu7042897openalex-snapshot
The Queuine Micronutrient: Charting a Course from Microbe to Man
inferredcites →https://doi.org/10.5604/17322693.1208033openalex-snapshot
From tyrosine to melanin: Signaling pathways and factors regulating melanogenesis
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The global burden of yellow fever
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