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Differential methanogenic archaea-induced TLR8-dependent signaling is governed by NF-κB p65- and STAT1/2-controlled gene classes
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)
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Gut colonization with methanobrevibacter smithii is associated with childhood weight development
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Transcriptional regulation of increased CCL2 expression in pulmonary fibrosis involves nuclear factor-κB and activator protein-1
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Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling
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Parsing the Interferon Transcriptional Network and Its Disease Associations
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From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
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Toll-like Receptors and the Control of Immunity
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The Activation of IL-1-Induced Enhancers Depends on TAK1 Kinase Activity and NF-κB p65
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Small-Molecule TLR8 Antagonists via Structure-Based Rational Design
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Perspectives on microbial community in anaerobic digestion with emphasis on environmental parameters: A systematic review
inferredcites →https://doi.org/10.1016/j.clim.2015.05.014openalex-snapshot
Immune–microbiota interactions in health and disease
inferredcites →https://doi.org/10.1016/j.clim.2016.12.005openalex-snapshot
Estrogen-regulated STAT1 activation promotes TLR8 expression to facilitate signaling via microRNA-21 in systemic lupus erythematosus
inferredcites →https://doi.org/10.1016/j.coi.2013.11.003openalex-snapshot
Insights into phagocytosis-coupled activation of pattern recognition receptors and inflammasomes
inferredcites →https://doi.org/10.1016/j.immuni.2005.06.008openalex-snapshot
Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA
inferredcites →https://doi.org/10.1016/j.immuni.2014.12.010openalex-snapshot
NOD1 and NOD2: Signaling, Host Defense, and Inflammatory Disease
inferredcites →https://doi.org/10.1016/j.jaci.2016.06.018openalex-snapshot
Endosomal recognition of Lactococcus lactis G121 and its RNA by dendritic cells is key to its allergy-protective effects
inferredcites →https://doi.org/10.1016/j.jaci.2019.02.009openalex-snapshot
Intestinal archaea inversely associated with childhood asthma
inferredcites →https://doi.org/10.1016/j.jconrel.2022.01.030openalex-snapshot
Particle uptake driven phagocytosis in macrophages and neutrophils enhances bacterial clearance
inferredcites →https://doi.org/10.1016/j.jhep.2022.09.027openalex-snapshot
Safety and efficacy of the oral TLR8 agonist selgantolimod in individuals with chronic hepatitis B under viral suppression
inferredcites →https://doi.org/10.1016/j.jim.2021.113048openalex-snapshot
Performance of a commercially available multiplex platform in the assessment of circulating cytokines and chemokines in patients with rheumatoid arthritis and osteoarthritis
inferredcites →https://doi.org/10.1016/j.mib.2022.102146openalex-snapshot
Archaeal key-residents within the human microbiome: characteristics, interactions and involvement in health and disease
inferredcites →https://doi.org/10.1016/j.micpath.2018.01.029openalex-snapshot
Alterations of the human gut Methanobrevibacter smithii as a biomarker for inflammatory bowel diseases
inferredcites →https://doi.org/10.1016/j.sbi.2024.102913openalex-snapshot
RNA recognition in toll-like receptor signaling
inferredcites →https://doi.org/10.1016/j.synbio.2023.12.007openalex-snapshot
Good and bad dispositions between archaea and bacteria in the human gut: New insights from metagenomic survey and co-occurrence analysis
inferredcites →https://doi.org/10.1016/s0168-6496(01)00200-8openalex-snapshot
Molecular ecology of extremely halophilic Archaea and Bacteria
inferredcites →https://doi.org/10.1016/s0378-1097(01)00051-9openalex-snapshot
Identification of archaeal rDNA from subgingival dental plaque by PCR amplification and sequence analysis
inferredcites →https://doi.org/10.1016/s0959-437x(98)80032-4openalex-snapshot
Everything in moderation: Archaea as ‘non-extremophiles’
inferredcites →https://doi.org/10.1021/jacs.3c05473openalex-snapshot
Archaeal Glycerolipids Are Recognized by C-Type Lectin Receptor Mincle
inferredcites →https://doi.org/10.1038/nature04768openalex-snapshot
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4
inferredcites →https://doi.org/10.1038/nature25986openalex-snapshot
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
inferredcites →https://doi.org/10.1038/nbt0816-888dopenalex-snapshot
Erratum: Near-optimal probabilistic RNA-seq quantification
inferredcites →https://doi.org/10.1038/nchembio.2518openalex-snapshot
Small-molecule inhibition of TLR8 through stabilization of its resting state
inferredcites →https://doi.org/10.1038/ni1110openalex-snapshot
The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses
inferredcites →https://doi.org/10.1038/ni1196openalex-snapshot
Interactions of NF-κB with chromatin: the art of being at the right place at the right time
inferredcites →https://doi.org/10.1038/nmeth.4324openalex-snapshot
Differential analysis of RNA-seq incorporating quantification uncertainty
inferredcites →https://doi.org/10.1038/nprot.2006.27openalex-snapshot
Protocol for the fast chromatin immunoprecipitation (ChIP) method
inferredcites →https://doi.org/10.1038/nri2634openalex-snapshot
Transcriptional control of the inflammatory response
inferredcites →https://doi.org/10.1038/nri3581openalex-snapshot
Regulation of type I interferon responses
inferredcites →https://doi.org/10.1038/nrmicro1852openalex-snapshot
Mesophilic crenarchaeota: proposal for a third archaeal phylum, the Thaumarchaeota
inferredcites →https://doi.org/10.1038/s41392-023-01557-7openalex-snapshot
Vaccine adjuvants: mechanisms and platforms
inferredcites →https://doi.org/10.1038/s41467-017-02640-8openalex-snapshot
Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
inferredcites →https://doi.org/10.1038/s41467-019-10970-yopenalex-snapshot
A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription
inferredcites →https://doi.org/10.1038/s41467-022-34667-xopenalex-snapshot
Metagenomics of Parkinson’s disease implicates the gut microbiome in multiple disease mechanisms
inferredcites →https://doi.org/10.1038/s41467-024-52037-7openalex-snapshot
Targeted isolation of Methanobrevibacter strains from fecal samples expands the cultivated human archaeome
inferredcites →https://doi.org/10.1038/s41467-025-60271-wopenalex-snapshot
Proteomic and metabolomic profiling of extracellular vesicles produced by human gut archaea
inferredcites →https://doi.org/10.1038/s41564-021-01020-9openalex-snapshot
A catalogue of 1,167 genomes from the human gut archaeome
inferredcites →https://doi.org/10.1038/s41575-022-00673-zopenalex-snapshot
Methanogenic archaea in the human gastrointestinal tract
inferredcites →https://doi.org/10.1038/s41577-020-0285-6openalex-snapshot
Defining trained immunity and its role in health and disease
inferredcites →https://doi.org/10.1038/s41596-024-01020-zopenalex-snapshot
Using clusterProfiler to characterize multiomics data
inferredcites →https://doi.org/10.1038/s41598-017-04197-4openalex-snapshot
Human age and skin physiology shape diversity and abundance of Archaea on skin
inferredcites →https://doi.org/10.1038/s41598-021-86202-5openalex-snapshot
Phagocytosis of microparticles increases responsiveness of macrophage-like cell lines U937 and THP-1 to bacterial lipopolysaccharide and lipopeptide
inferredcites →https://doi.org/10.1042/bj20140644openalex-snapshot
STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response and antiviral activity in the absence of STAT1
inferredcites →https://doi.org/10.1073/pnas.0308766101openalex-snapshot
Methanogenic Archaea and human periodontal disease
inferredcites →https://doi.org/10.1073/pnas.0909122107openalex-snapshot
Inducible Foxp3 + regulatory T-cell development by a commensal bacterium of the intestinal microbiota
inferredcites →https://doi.org/10.1073/pnas.89.12.5685openalex-snapshot
Archaea in coastal marine environments.
inferredcites →https://doi.org/10.1073/pnas.90.21.10193openalex-snapshot
Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8.
inferredcites →https://doi.org/10.1074/jbc.274.45.32048openalex-snapshot
Peroxisome Proliferator-activated Receptor α Negatively Regulates the Vascular Inflammatory Gene Response by Negative Cross-talk with Transcription Factors NF-κB and AP-1
inferredcites →https://doi.org/10.1074/jbc.r115.647099openalex-snapshot
The Role of Copper and Zinc Toxicity in Innate Immune Defense against Bacterial Pathogens
inferredcites →https://doi.org/10.1080/19490976.2024.2393756openalex-snapshot
Consistent signatures in the human gut microbiome of longevous populations
inferredcites →https://doi.org/10.1084/jem.179.4.1109openalex-snapshot
Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.
inferredcites →https://doi.org/10.1093/bioadv/vbac016openalex-snapshot
decoupleR: ensemble of computational methods to infer biological activities from omics data
inferredcites →https://doi.org/10.1093/bioinformatics/btr671openalex-snapshot
A novel significance score for gene selection and ranking
inferredcites →https://doi.org/10.1093/bioinformatics/btw354openalex-snapshot
MultiQC: summarize analysis results for multiple tools and samples in a single report
inferredcites →https://doi.org/10.1093/femsre/fuab021openalex-snapshot
Cofactor F420: an expanded view of its distribution, biosynthesis and roles in bacteria and archaea
inferredcites →https://doi.org/10.1093/nar/gkae909openalex-snapshot
KEGG: biological systems database as a model of the real world
inferredcites →https://doi.org/10.1093/nar/gks808openalex-snapshot
Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies
inferredcites →https://doi.org/10.1099/ijsem.0.006751openalex-snapshot
Expanding the cultivable human archaeome: Methanobrevibacter intestini sp. nov. and strain Methanobrevibacter smithii ‘GRAZ-2’ from human faeces
inferredcites →https://doi.org/10.1101/2025.06.12.659283openalex-snapshot
Methanobrevibacter smithii associates with colorectal cancer through trophic control of the cancer bacteriome
inferredcites →https://doi.org/10.1101/gr.240663.118openalex-snapshot
Benchmark and integration of resources for the estimation of human transcription factor activities
inferredcites →https://doi.org/10.1101/pdb.prot082628openalex-snapshot
ChIP–Quantitative Polymerase Chain Reaction (ChIP-qPCR)
inferredcites →https://doi.org/10.1111/febs.17123openalex-snapshot
Exploring the human archaeome: its relevance for health and disease, and its complex interplay with the human immune system
inferredcites →https://doi.org/10.1111/j.1399-302x.2009.00514.xopenalex-snapshot
Prevalence and molecular diversity of Archaea in subgingival pockets of periodontitis patients
inferredcites →https://doi.org/10.1126/science.1086823openalex-snapshot
Extending the Upper Temperature Limit for Life
inferredcites →https://doi.org/10.1126/science.1093616openalex-snapshot
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
inferredcites →https://doi.org/10.1126/science.1113319openalex-snapshot
Stimulus Specificity of Gene Expression Programs Determined by Temporal Control of IKK Activity
inferredcites →https://doi.org/10.1126/science.aaw9255openalex-snapshot
Vulnerability of the industrialized microbiota
inferredcites →https://doi.org/10.1128/iai.74.2.940-946.2006openalex-snapshot
Activation of Toll-Like Receptor 9 by DNA from Different Bacterial Species
inferredcites →https://doi.org/10.1128/mbio.00824-17openalex-snapshot
First Insights into the Diverse Human Archaeome: Specific Detection of Archaea in the Gastrointestinal Tract, Lung, and Nose and on Skin
inferredcites →https://doi.org/10.1128/mbio.03235-19openalex-snapshot
Syntrophy via Interspecies H 2 Transfer between Christensenella and Methanobrevibacter Underlies Their Global Cooccurrence in the Human Gut
inferredcites →https://doi.org/10.1128/mcb.10.5.2327openalex-snapshot
Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.
inferredcites →https://doi.org/10.1128/spectrum.00849-22openalex-snapshot
Mutual Exclusion of Methanobrevibacter Species in the Human Gut Microbiota Facilitates Directed Cultivation of a Candidatus Methanobrevibacter Intestini Representative
inferredcites →https://doi.org/10.1128/spectrum.01653-22openalex-snapshot
Methanogen Levels Are Significantly Associated with Fecal Microbiota Composition and Alpha Diversity in Healthy Adults and Irritable Bowel Syndrome Patients
inferredcites →https://doi.org/10.1158/1078-0432.ccr-16-1934openalex-snapshot
Phase Ib Trial of the Toll-like Receptor 8 Agonist, Motolimod (VTX-2337), Combined with Cetuximab in Patients with Recurrent or Metastatic SCCHN
inferredcites →https://doi.org/10.1159/000097977openalex-snapshot
Interferon-β Is a Potent Inducer of Interferon Regulatory Factor-1/2-Dependent IP-10/CXCL10 Expression in Primary Human Endothelial Cells
inferredcites →https://doi.org/10.1182/blood-2007-12-077917openalex-snapshot
The phagocytes: neutrophils and monocytes
inferredcites →https://doi.org/10.1186/s12866-025-03921-9openalex-snapshot
Age-related dynamics of predominant methanogenic archaea in the human gut microbiome
inferredcites →https://doi.org/10.1186/s12934-017-0793-7openalex-snapshot
Flow cytometric quantification, sorting and sequencing of methanogenic archaea based on F420 autofluorescence
inferredcites →https://doi.org/10.1186/s40168-022-01335-7openalex-snapshot
Landscape of the gut archaeome in association with geography, ethnicity, urbanization, and diet in the Chinese population
inferredcites →https://doi.org/10.1189/jlb.0808504openalex-snapshot
TLR7 and TLR8 agonists trigger different signaling pathways for human dendritic cell maturation
inferredcites →https://doi.org/10.1371/journal.pone.0007063openalex-snapshot
High Prevalence of Methanobrevibacter smithii and Methanosphaera stadtmanae Detected in the Human Gut Using an Improved DNA Detection Protocol
inferredcites →https://doi.org/10.1371/journal.pone.0023326openalex-snapshot
Immunogenic Properties of Archaeal Species Found in Bioaerosols
inferredcites →https://doi.org/10.1371/journal.pone.0087734openalex-snapshot
Increased Prevalence of Methanosphaera stadtmanae in Inflammatory Bowel Diseases
inferredcites →https://doi.org/10.1371/journal.pone.0099411openalex-snapshot
The Intestinal Archaea Methanosphaera stadtmanae and Methanobrevibacter smithii Activate Human Dendritic Cells
inferredcites →https://doi.org/10.2147/jir.s368352openalex-snapshot
IFN-γ and LPS Induce Synergistic Expression of CCL2 in Monocytic Cells via H3K27 Acetylation
inferredcites →https://doi.org/10.3389/fimmu.2017.01535openalex-snapshot
The Human-Associated Archaeon Methanosphaera stadtmanae Is Recognized through Its RNA and Induces TLR8-Dependent NLRP3 Inflammasome Activation
inferredcites →https://doi.org/10.3389/fimmu.2018.01135openalex-snapshot
A Positive Feedback Amplifier Circuit That Regulates Interferon (IFN)-Stimulated Gene Expression and Controls Type I and Type II IFN Responses
inferredcites →https://doi.org/10.3389/fimmu.2018.01425openalex-snapshot
Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites
inferredcites →https://doi.org/10.3389/fimmu.2019.01209openalex-snapshot
Human Toll-like Receptor 8 (TLR8) Is an Important Sensor of Pyogenic Bacteria, and Is Attenuated by Cell Surface TLR Signaling
inferredcites →https://doi.org/10.3389/fimmu.2019.01902openalex-snapshot
ADAM17-Mediated Reduction in CD14++CD16+ Monocytes ex vivo and Reduction in Intermediate Monocytes With Immune Paresis in Acute Pancreatitis and Acute Alcoholic Hepatitis
inferredcites →https://doi.org/10.3389/fmicb.2019.02796openalex-snapshot
Exploring the Archaeome: Detection of Archaeal Signatures in the Human Body
inferredcites →https://doi.org/10.3389/fpubh.2019.00038openalex-snapshot
Nine Cases of Methanogenic Archaea in Refractory Sinusitis, an Emerging Clinical Entity
inferredcites →https://doi.org/10.3390/applmicrobiol4010012openalex-snapshot
Methanogenic Archaea Quantification in the Human Gut Microbiome with F420 Autofluorescence-Based Flow Cytometry
inferredcites →https://doi.org/10.3390/cells11081287openalex-snapshot
The Relevance of the Bacterial Microbiome, Archaeome and Mycobiome in Pediatric Asthma and Respiratory Disorders
inferredcites →https://doi.org/10.3390/life12060857openalex-snapshot
Anti-Inflammatory Effects of Cicadidae Periostracum Extract and Oleic Acid through Inhibiting Inflammatory Chemokines Using PCR Arrays in LPS-Induced Lung inflammation In Vitro
inferredcites →https://doi.org/10.3402/jom.v3i0.5940openalex-snapshot
Methanogenic Archaea and oral infections – ways to unravel the black box
inferredcites →https://doi.org/10.4049/jimmunol.1403173openalex-snapshot
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes
inferredcites →https://doi.org/10.4049/jimmunol.1500530openalex-snapshot
Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses
inferredcites →https://doi.org/10.4049/jimmunol.1800912openalex-snapshot
Hydroxylase Inhibition Selectively Induces Cell Death in Monocytes
inferredcites →https://doi.org/10.4137/grsb.s11433openalex-snapshot
A Comprehensive Profile of ChIP-Seq-Based STAT1 Target Genes Suggests the Complexity of STAT1-Mediated Gene Regulatory Mechanisms
inferredcites →https://doi.org/10.5009/gnl15588openalex-snapshot
Irritable Bowel Syndrome, Particularly the Constipation-Predominant Form, Involves an Increase inMethanobrevibacter smithii, Which Is Associated with Higher Methane Production
inferredcites →https://doi.org/10.7554/elife.106443openalex-snapshot
Toll-like receptors (TLRs) in the trained immunity era
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