On the public citation graph

Phenotype of mice carrying an NMDA receptor GluN2B protein-truncating variant associated with intellectual disability

https://doi.org/10.1101/2025.10.02.680004

0 signed · 88 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jcc.20945openalex-snapshot

CHARMM‐GUI: A web‐based graphical user interface for CHARMM

inferredcites →https://doi.org/10.1006/jmbi.1993.1626openalex-snapshot

Comparative Protein Modelling by Satisfaction of Spatial Restraints

inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

inferredcites →https://doi.org/10.1007/978-1-0716-3830-9_3openalex-snapshot

Analysis of Surface Expression of NMDAR Subunits in Primary Hippocampal Neurons

inferredcites →https://doi.org/10.1007/978-1-4939-7493-1_7openalex-snapshot

Perseus: A Bioinformatics Platform for Integrative Analysis of Proteomics Data in Cancer Research

inferredcites →https://doi.org/10.1007/s00018-023-05062-6openalex-snapshot

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids

inferredcites →https://doi.org/10.1016/0006-3223(93)90300-3openalex-snapshot

A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder

inferredcites →https://doi.org/10.1016/0896-6273(94)90210-0openalex-snapshot

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

inferredcites →https://doi.org/10.1016/0896-6273(94)90350-6openalex-snapshot

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

inferredcites →https://doi.org/10.1016/j.ajhg.2010.07.019openalex-snapshot

Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia Cohorts

inferredcites →https://doi.org/10.1016/j.biopsych.2005.09.025openalex-snapshot

Sensorimotor Gating Deficits in Adults with Autism

inferredcites →https://doi.org/10.1016/j.celrep.2018.09.089openalex-snapshot

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences

inferredcites →https://doi.org/10.1016/j.jpba.2022.114926openalex-snapshot

Optimization of a detergent-based protocol for membrane proteins purification from mammalian cells

inferredcites →https://doi.org/10.1016/j.jphs.2016.10.002openalex-snapshot

Human GRIN2B variants in neurodevelopmental disorders

inferredcites →https://doi.org/10.1016/j.neuron.2008.09.039openalex-snapshot

Contribution of Hippocampal and Extra-Hippocampal NR2B-Containing NMDA Receptors to Performance on Spatial Learning Tasks

inferredcites →https://doi.org/10.1016/j.neuron.2011.08.007openalex-snapshot

Distinct Modes of AMPA Receptor Suppression at Developing Synapses by GluN2A and GluN2B: Single-Cell NMDA Receptor Subunit Deletion In Vivo

inferredcites →https://doi.org/10.1016/j.neuron.2014.01.035openalex-snapshot

Distinct Functional and Pharmacological Properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA Receptors

inferredcites →https://doi.org/10.1016/j.neuropharm.2013.01.016openalex-snapshot

Influence of GluN2 subunit identity on NMDA receptor function

inferredcites →https://doi.org/10.1016/j.neuropharm.2021.108805openalex-snapshot

Clinical and therapeutic significance of genetic variation in the GRIN gene family encoding NMDARs

inferredcites →https://doi.org/10.1016/j.neuroscience.2010.01.022openalex-snapshot

Organization of NMDA receptors at extrasynaptic locations

inferredcites →https://doi.org/10.1016/j.softx.2015.06.001openalex-snapshot

GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers

inferredcites →https://doi.org/10.1016/j.tibtech.2018.12.002openalex-snapshot

The Ultimate qPCR Experiment: Producing Publication Quality, Reproducible Data the First Time

inferredcites →https://doi.org/10.1016/j.tins.2023.07.001openalex-snapshot

Nonsense-mediated mRNA decay in neuronal physiology and neurodegeneration

inferredcites →https://doi.org/10.1016/j.ymgme.2018.06.013openalex-snapshot

Alleles with more than one mutation can complicate genotype/phenotype studies in Mendelian disorders: Lessons from Gaucher disease

inferredcites →https://doi.org/10.1016/s0026-895x(25)13275-6openalex-snapshot

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

inferredcites →https://doi.org/10.1016/s0028-3908(01)00188-5openalex-snapshot

Functional expression of distinct NMDA channel subunits tagged with green fluorescent protein in hippocampal neurons in culture

inferredcites →https://doi.org/10.1016/s0896-6273(00)80051-3openalex-snapshot

Impairment of Suckling Response, Trigeminal Neuronal Pattern Formation, and Hippocampal LTD in NMDA Receptor ε2 Subunit Mutant Mice

inferredcites →https://doi.org/10.1016/s0896-6273(02)00776-6openalex-snapshot

Subunit-Specific NMDA Receptor Trafficking to Synapses

inferredcites →https://doi.org/10.1021/acs.jctc.5b00935openalex-snapshot

CHARMM-GUI Input Generator for NAMD, GROMACS, AMBER, OpenMM, and CHARMM/OpenMM Simulations Using the CHARMM36 Additive Force Field

inferredcites →https://doi.org/10.1021/jp101759qopenalex-snapshot

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

inferredcites →https://doi.org/10.1038/357686a0openalex-snapshot

Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse

inferredcites →https://doi.org/10.1038/368144a0openalex-snapshot

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

inferredcites →https://doi.org/10.1038/nature13548openalex-snapshot

NMDA receptor structures reveal subunit arrangement and pore architecture

inferredcites →https://doi.org/10.1038/ng.677openalex-snapshot

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes

inferredcites →https://doi.org/10.1038/nrn2851openalex-snapshot

Behavioural phenotyping assays for mouse models of autism

inferredcites →https://doi.org/10.1038/s41386-023-01614-3openalex-snapshot

Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry

inferredcites →https://doi.org/10.1038/s41580-019-0126-2openalex-snapshot

Quality and quantity control of gene expression by nonsense-mediated mRNA decay

inferredcites →https://doi.org/10.1038/s42003-020-0963-8openalex-snapshot

Synapse elimination activates a coordinated homeostatic presynaptic response in an autaptic circuit

inferredcites →https://doi.org/10.1038/srep27459openalex-snapshot

IVA cloning: A single-tube universal cloning system exploiting bacterial In Vivo Assembly

inferredcites →https://doi.org/10.1038/srep33311openalex-snapshot

Mutation screening of GRIN2B in schizophrenia and autism spectrum disorder in a Japanese population

inferredcites →https://doi.org/10.1038/tp.2011.52openalex-snapshot

Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia

inferredcites →https://doi.org/10.1046/j.0953-816x.2001.01620.xopenalex-snapshot

Roles of the glutamate receptor ε2 and δ2 subunits in the potentiation and prepulse inhibition of the acoustic startle reflex

inferredcites →https://doi.org/10.1063/1.470117openalex-snapshot

A smooth particle mesh Ewald method

inferredcites →https://doi.org/10.1073/pnas.0605238103openalex-snapshot

NMDA receptor surface mobility depends on NR2A-2B subunits

inferredcites →https://doi.org/10.1073/pnas.1217549110openalex-snapshot

Glutamate receptor desensitization is mediated by changes in quaternary structure of the ligand binding domain

inferredcites →https://doi.org/10.1074/jbc.m110.182600openalex-snapshot

Triheteromeric NR1/NR2A/NR2B Receptors Constitute the Major N-Methyl-d-aspartate Receptor Population in Adult Hippocampal Synapses

inferredcites →https://doi.org/10.1074/jbc.m402599200openalex-snapshot

Export from the Endoplasmic Reticulum of Assembled N-Methyl-D-aspartic Acid Receptors Is Controlled by a Motif in the C Terminus of the NR2 Subunit

inferredcites →https://doi.org/10.1074/mcp.m113.037309openalex-snapshot

A “Proteomic Ruler” for Protein Copy Number and Concentration Estimation without Spike-in Standards

inferredcites →https://doi.org/10.1093/brain/awaa051openalex-snapshot

A catalogue of new incidence estimates of monogenic neurodevelopmental disorders caused by de novo variants

inferredcites →https://doi.org/10.1093/brain/awy304openalex-snapshot

GRIN2A -related disorders: genotype and functional consequence predict phenotype

inferredcites →https://doi.org/10.1093/hmg/ddaa220openalex-snapshot

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function

inferredcites →https://doi.org/10.1093/jmcb/mjab022openalex-snapshot

Regulation of nonsense-mediated mRNA decay in neural development and disease

inferredcites →https://doi.org/10.1093/nar/gkaa1100openalex-snapshot

UniProt: the universal protein knowledgebase in 2021

inferredcites →https://doi.org/10.1101/gr.275528.121openalex-snapshot

Three-dimensional missense tolerance ratio analysis

inferredcites →https://doi.org/10.1111/bph.15529openalex-snapshot

Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms

inferredcites →https://doi.org/10.1111/epi.18124openalex-snapshot

WONOEP appraisal: Genetic insights into early onset epilepsies

inferredcites →https://doi.org/10.1111/j.0014-3820.2003.tb00377.xopenalex-snapshot

PERSPECTIVE: EVOLUTION AND DETECTION OF GENETIC ROBUSTNESS

inferredcites →https://doi.org/10.1111/j.1476-5381.2011.01816.xopenalex-snapshot

Access of inhibitory neurosteroids to the NMDA receptor

inferredcites →https://doi.org/10.1113/jp278705openalex-snapshot

From bedside‐to‐bench: What disease‐associated variants are teaching us about the NMDA receptor

inferredcites →https://doi.org/10.1124/mol.107.037333openalex-snapshot

Subunit-Specific Agonist Activity at NR2A-, NR2B-, NR2C-, and NR2D-Containing N-Methyl-d-aspartate Glutamate Receptors

inferredcites →https://doi.org/10.1124/mol.51.1.79openalex-snapshot

The Majority of N-Methyl-d-Aspartate Receptor Complexes in Adult Rat Cerebral Cortex Contain at Least Three Different Subunits (NR1/NR2A/NR2B)

inferredcites →https://doi.org/10.1124/pharmrev.120.000131openalex-snapshot

Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels

inferredcites →https://doi.org/10.1126/science.1251915openalex-snapshot

Crystal structure of a heterotetrameric NMDA receptor ion channel

inferredcites →https://doi.org/10.1126/science.256.5060.1217openalex-snapshot

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

inferredcites →https://doi.org/10.1136/jmedgenet-2016-104509openalex-snapshot

GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects

inferredcites →https://doi.org/10.1146/annurev.pharmtox.43.100901.135803openalex-snapshot

Trafficking of NMDA Receptors

inferredcites →https://doi.org/10.1152/jn.1998.79.2.555openalex-snapshot

Functional and Pharmacological Differences Between Recombinant N -Methyl- d -Aspartate Receptors

inferredcites →https://doi.org/10.1186/s12864-022-08435-6openalex-snapshot

Frameshift and wild-type proteins are often highly similar because the genetic code and genomes were optimized for frameshift tolerance

inferredcites →https://doi.org/10.1186/s13229-020-00376-9openalex-snapshot

Assessing the requirements of prenatal UBE3A expression for rescue of behavioral phenotypes in a mouse model for Angelman syndrome

inferredcites →https://doi.org/10.1371/journal.pbio.3000717openalex-snapshot

Early correction of synaptic long-term depression improves abnormal anxiety-like behavior in adult GluN2B-C456Y-mutant mice

inferredcites →https://doi.org/10.1371/journal.pcbi.1002522openalex-snapshot

Emergence of a Small-World Functional Network in Cultured Neurons

inferredcites →https://doi.org/10.1371/journal.pcbi.1004559openalex-snapshot

Gene Expression Switching of Receptor Subunits in Human Brain Development

inferredcites →https://doi.org/10.1523/jneurosci.0829-13.2013openalex-snapshot

Triheteromeric NMDA Receptors at Hippocampal Synapses

inferredcites →https://doi.org/10.1523/jneurosci.0956-07.2007openalex-snapshot

Distinct Structural and Ionotropic Roles of NMDA Receptors in Controlling Spine and Synapse Stability

inferredcites →https://doi.org/10.1523/jneurosci.1210-14.2014openalex-snapshot

GluN2B-Containing NMDA Receptors Promote Glutamate Synapse Development in Hippocampal Interneurons

inferredcites →https://doi.org/10.1523/jneurosci.17-07-02469.1997openalex-snapshot

NR2A Subunit Expression Shortens NMDA Receptor Synaptic Currents in Developing Neocortex

inferredcites →https://doi.org/10.1523/jneurosci.18-08-02954.1998openalex-snapshot

Evidence for a Tetrameric Structure of Recombinant NMDA Receptors

inferredcites →https://doi.org/10.1523/jneurosci.2155-07.2007openalex-snapshot

NMDA Di-Heteromeric Receptor Populations and Associated Proteins in Rat Hippocampus

inferredcites →https://doi.org/10.1523/jneurosci.22-20-08902.2002openalex-snapshot

Relationship between Availability of NMDA Receptor Subunits and Their Expression at the Synapse

inferredcites →https://doi.org/10.1523/jneurosci.2291-23.2024openalex-snapshot

Characterization of Mice Carrying a Neurodevelopmental Disease-Associated GluN2B(L825V) Variant

inferredcites →https://doi.org/10.1523/jneurosci.3793-07.2007openalex-snapshot

NR2B Signaling Regulates the Development of Synaptic AMPA Receptor Current

inferredcites →https://doi.org/10.1523/jneurosci.5239-07.2008openalex-snapshot

Masking of the Endoplasmic Reticulum Retention Signals during Assembly of the NMDA Receptor

inferredcites →https://doi.org/10.2144/000114325openalex-snapshot

Two-step Protocol For Preparing Adherent Cells For High-Throughput Flow Cytometry

inferredcites →https://doi.org/10.33549/physiolres.935346openalex-snapshot

Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology

inferredcites →https://doi.org/10.3389/fncel.2022.907560openalex-snapshot

Protein quality control of N-methyl-D-aspartate receptors

inferredcites →https://doi.org/10.3389/fnmol.2019.00185openalex-snapshot

NMDAR Hypofunction Animal Models of Schizophrenia

inferredcites →https://doi.org/10.3389/fnsyn.2022.1090865openalex-snapshot

GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms

inferredcites →https://doi.org/10.3390/biom9100546openalex-snapshot

NMDA Receptor Opening and Closing—Transitions of a Molecular Machine Revealed by Molecular Dynamics

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.