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Genome sequencing reveals that Streptococcus pneumoniae possesses a large and diverse repertoire of antimicrobial toxins

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.tim.2012.11.005openalex-snapshot
Influence of bacterial interactions on pneumococcal colonization of the nasopharynx
inferredcites →https://doi.org/10.1016/j.vaccine.2010.06.008openalex-snapshot
Serotypes 1, 7F and 19A became the leading causes of pediatric invasive pneumococcal infections in Portugal after 7 years of heptavalent conjugate vaccine use
inferredcites →https://doi.org/10.1016/j.vaccine.2015.03.012openalex-snapshot
Five winters of pneumococcal serotype replacement in UK carriage following PCV introduction
inferredcites →https://doi.org/10.1016/s0140-6736(09)61204-6openalex-snapshot
Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates
inferredcites →https://doi.org/10.1016/s0378-1097(00)00340-2openalex-snapshot
Allelic variation in a peptide-inducible two-component system of Streptococcus pneumoniae
inferredcites →https://doi.org/10.1016/s1473-3099(04)00938-7openalex-snapshot
Streptococcus pneumoniae colonisation: the key to pneumococcal disease
inferredcites →https://doi.org/10.1016/s1473-3099(15)00466-1openalex-snapshot
Alternatives to antibiotics—a pipeline portfolio review
inferredcites →https://doi.org/10.1038/349029a0openalex-snapshot
Localized sex in bacteria
inferredcites →https://doi.org/10.1038/ng.1072openalex-snapshot
Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event
inferredcites →https://doi.org/10.1038/ng.2625openalex-snapshot
Population genomics of post-vaccine changes in pneumococcal epidemiology
inferredcites →https://doi.org/10.1038/ng.2895openalex-snapshot
Dense genomic sampling identifies highways of pneumococcal recombination
inferredcites →https://doi.org/10.1038/nmeth.1923openalex-snapshot
Fast gapped-read alignment with Bowtie 2
inferredcites →https://doi.org/10.1038/srep42976openalex-snapshot
Pneumococcal prophages are diverse, but not without structure or history
inferredcites →https://doi.org/10.1039/c2np20085fopenalex-snapshot
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature
inferredcites →https://doi.org/10.1073/pnas.0500879102openalex-snapshot
Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae : Genetic requirements
inferredcites →https://doi.org/10.1086/374624openalex-snapshot
Clonal Relationships between Invasive and CarriageStreptococcus pneumoniaeand Serotype‐ and Clone‐Specific Differences in Invasive Disease Potential
inferredcites →https://doi.org/10.1093/aje/kwp351openalex-snapshot
Between-Strain Competition in Acquisition and Clearance of Pneumococcal Carriage—Epidemiologic Evidence From a Longitudinal Study of Day-Care Children
inferredcites →https://doi.org/10.1093/bioinformatics/bti553openalex-snapshot
ACT: the Artemis comparison tool
inferredcites →https://doi.org/10.1093/bioinformatics/btm404openalex-snapshot
Clustal W and Clustal X version 2.0
inferredcites →https://doi.org/10.1093/bioinformatics/btu031openalex-snapshot
InterProScan 5: genome-scale protein function classification
inferredcites →https://doi.org/10.1093/bioinformatics/btu153openalex-snapshot
Prokka: rapid prokaryotic genome annotation
inferredcites →https://doi.org/10.1093/bioinformatics/btv171openalex-snapshot
M e D u S a : a multi-draft based scaffolder
inferredcites →https://doi.org/10.1093/bioinformatics/btv421openalex-snapshot
Roary: rapid large-scale prokaryote pan genome analysis
inferredcites →https://doi.org/10.1093/infdis/jis703openalex-snapshot
Pneumococcal Capsular Switching: A Historical Perspective
inferredcites →https://doi.org/10.1093/infdis/jix647openalex-snapshot
Diverse Streptococcus pneumoniae Strains Drive a Mucosal-Associated Invariant T-Cell Response Through Major Histocompatibility Complex class I–Related Molecule–Dependent and Cytokine-Driven Pathways
inferredcites →https://doi.org/10.1093/jac/dkf048openalex-snapshot
Macrolide-treated Pseudomonas aeruginosa induces paradoxical host responses in the lungs of mice and a high mortality rate
inferredcites →https://doi.org/10.1093/nar/gkq1189openalex-snapshot
CDD: a Conserved Domain Database for the functional annotation of proteins
inferredcites →https://doi.org/10.1093/nar/gkt391openalex-snapshot
BAGEL3: automated identification of genes encoding bacteriocins and (non-)bactericidal posttranslationally modified peptides
inferredcites →https://doi.org/10.1093/nar/gku1003openalex-snapshot
STRING v10: protein–protein interaction networks, integrated over the tree of life
inferredcites →https://doi.org/10.1093/nar/gkv437openalex-snapshot
antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters
inferredcites →https://doi.org/10.1093/nar/gkw290openalex-snapshot
Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees
inferredcites →https://doi.org/10.1098/rstb.2009.0055openalex-snapshot
Social evolution in micro-organisms and a Trojan horse approach to medical intervention strategies
inferredcites →https://doi.org/10.1099/00221287-145-11-3155openalex-snapshot
Synthesis of lactococcin 972, a bacteriocin produced by Lactococcus lactis IPLA 972, depends on the expression of a plasmid-encoded bicistronic operon The GenBank accession number for the sequence reported in this paper is AJ002203.
inferredcites →https://doi.org/10.1099/mic.0.000237openalex-snapshot
Salivaricin E and abundant dextranase activity may contribute to the anti-cariogenic potential of the probiotic candidate Streptococcus salivarius JH
inferredcites →https://doi.org/10.1101/gr.074492.107openalex-snapshot
Velvet: Algorithms for de novo short read assembly using de Bruijn graphs
inferredcites →https://doi.org/10.1111/j.1365-2958.1991.tb00821.xopenalex-snapshot
Interspecies recombinational events during the evolution of altered PBP 2x genes in penicillin‐resistant clinical isolates of Streptococcus pneumoniae
inferredcites →https://doi.org/10.1111/j.1365-2958.1991.tb02155.xopenalex-snapshot
Horizontal transfer of multiple penicillin‐binding protein genes, and capsular biosynthetic genes, in natural populations of Streptococcus pneumoniae
inferredcites →https://doi.org/10.1111/mmi.13029openalex-snapshot
A new quorum‐sensing system ( TprA / PhrA ) for S treptococcus pneumoniae D 39 that regulates a lantibiotic biosynthesis gene cluster
inferredcites →https://doi.org/10.1111/mmi.13721openalex-snapshot
A novel streptococcal cell–cell communication peptide promotes pneumococcal virulence and biofilm formation
inferredcites →https://doi.org/10.1126/science.1198545openalex-snapshot
Rapid Pneumococcal Evolution in Response to Clinical Interventions
inferredcites →https://doi.org/10.1128/9781555816537.ch9openalex-snapshot
Pneumococcal Carriage
inferredcites →https://doi.org/10.1128/aac.45.6.1721-1729.2001openalex-snapshot
Antimicrobial Resistance among Clinical Isolates of Streptococcus pneumoniae in the United States during 1999–2000, Including a Comparison of Resistance Rates since 1994–1995
inferredcites →https://doi.org/10.1128/aem.00730-09openalex-snapshot
Identification of a Novel Two-Peptide Lantibiotic, Lichenicidin, following Rational Genome Mining for LanM Proteins
inferredcites →https://doi.org/10.1128/cmr.3.2.171openalex-snapshot
Pneumococcal resistance to antibiotics
inferredcites →https://doi.org/10.1128/iai.01775-05openalex-snapshot
The blp Bacteriocins of Streptococcus pneumoniae Mediate Intraspecies Competition both In Vitro and In Vivo
inferredcites →https://doi.org/10.1128/jb.01343-08openalex-snapshot
Role of Conjugative Elements in the Evolution of the Multidrug-Resistant Pandemic CloneStreptococcus pneumoniaeSpain23FST81
inferredcites →https://doi.org/10.1128/jb.01553-09openalex-snapshot
The Abi Proteins and Their Involvement in Bacteriocin Self-Immunity
inferredcites →https://doi.org/10.1128/jcm.00744-15openalex-snapshot
Genomics Reveals the Worldwide Distribution of Multidrug-Resistant Serotype 6E Pneumococci
inferredcites →https://doi.org/10.1128/mbio.00173-15openalex-snapshot
Genetic Stabilization of the Drug-Resistant PMEN1 Pneumococcus Lineage by Its Distinctive DpnIII Restriction-Modification System
inferredcites →https://doi.org/10.1128/mbio.00179-11openalex-snapshot
Conserved Mutations in the Pneumococcal Bacteriocin Transporter Gene, blpA , Result in a Complex Population Consisting of Producers and Cheaters
inferredcites →https://doi.org/10.1128/mbio.01656-15openalex-snapshot
Characterization of a Multipeptide Lantibiotic Locus in Streptococcus pneumoniae
inferredcites →https://doi.org/10.1186/1471-2105-11-595openalex-snapshot
BIGSdb: Scalable analysis of bacterial genome variation at the population level
inferredcites →https://doi.org/10.1186/1471-2164-15-983openalex-snapshot
Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in anaerobic bacteria
inferredcites →https://doi.org/10.1186/1471-2180-10-22openalex-snapshot
BACTIBASE second release: a database and tool platform for bacteriocin characterization
inferredcites →https://doi.org/10.1186/gb-2010-11-10-r106openalex-snapshot
Differential expression analysis for sequence count data
inferredcites →https://doi.org/10.1186/s12864-015-1729-4openalex-snapshot
Genomic analyses of pneumococci reveal a wide diversity of bacteriocins – including pneumocyclicin, a novel circular bacteriocin
inferredcites →https://doi.org/10.1186/s12879-017-2713-1openalex-snapshot
Antimicrobial resistance in Africa: a systematic review
inferredcites →https://doi.org/10.1371/journal.pcbi.1003788openalex-snapshot
Defining the Estimated Core Genome of Bacterial Populations Using a Bayesian Decision Model
inferredcites →https://doi.org/10.1371/journal.pcbi.1004041openalex-snapshot
ClonalFrameML: Efficient Inference of Recombination in Whole Bacterial Genomes
inferredcites →https://doi.org/10.1371/journal.pgen.1003868openalex-snapshot
Dominant Role of Nucleotide Substitution in the Diversification of Serotype 3 Pneumococci over Decades and during a Single Infection
inferredcites →https://doi.org/10.1371/journal.pone.0009490openalex-snapshot
FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments
inferredcites →https://doi.org/10.1371/journal.pone.0033320openalex-snapshot
A Functional Genomics Approach to Establish the Complement of Carbohydrate Transporters in Streptococcus pneumoniae
inferredcites →https://doi.org/10.1371/journal.ppat.1006339openalex-snapshot
Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage
inferredcites →https://doi.org/10.1542/peds.2004-2338openalex-snapshot
Post-PCV7 Changes in Colonizing Pneumococcal Serotypes in 16 Massachusetts Communities, 2001 and 2004
inferredcites →https://doi.org/10.1542/peds.2008-1702openalex-snapshot
Serotype 19A Is the Most Common Serotype Causing Invasive Pneumococcal Infections in Children
inferredcites →https://doi.org/10.3389/fmicb.2016.00706openalex-snapshot
Bacterial Cell–Cell Communication in the Host via RRNPP Peptide-Binding Regulators
inferredcites →https://doi.org/10.4161/mge.25582openalex-snapshot
The DpnI/DpnII pneumococcal system, defense against foreign attack without compromising genetic exchange

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inferred← citeshttps://doi.org/10.3389/fmicb.2018.02012openalex-snapshot
Genome Sequencing Reveals a Large and Diverse Repertoire of Antimicrobial Peptides
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