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Genome-Wide Association Study of Body Fat Distribution identifies Novel Adiposity Loci and Sex-Specific Genetic Effects

https://doi.org/10.1101/207498

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1 of the 70 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1016/j.cmet.2013.05.002 (notice 2020-10-06).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Sp1 Is Necessary for Gene Activation of Adamts17 by Estrogen

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Reliability and accuracy of segmental bioelectrical impedance analysis for assessing muscle and fat mass in older Europeans: a comparison with dual-energy X-ray absorptiometry

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GCTA: A Tool for Genome-wide Complex Trait Analysis

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Gene × Environment Interaction Studies Have Not Properly Controlled for Potential Confounders: The Problem and the (Simple) Solution

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52 Genetic Loci Influencing Myocardial Mass

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Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

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Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants

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Myth and paradox of coronary risk and the menopause

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Versican: a versatile extracellular matrix proteoglycan in cell biology

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Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: The evidence report

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FTO genotype is associated with phenotypic variability of body mass index

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New genetic loci link adipose and insulin biology to body fat distribution

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The UK10K project identifies rare variants in health and disease

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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk

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Biological interpretation of genome-wide association studies using predicted gene functions

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Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

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Defining the role of common variation in the genomic and biological architecture of adult human height

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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

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An atlas of genetic correlations across human diseases and traits

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Common variants at ten loci influence QT interval duration in the QTGEN Study

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Genome-wide association study identifies 112 new loci for body mass index in the Japanese population

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Several common variants modulate heart rate, PR interval and QRS duration

inferredcites →https://doi.org/10.1038/ng.685openalex-snapshot

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.

inferredcites →https://doi.org/10.1038/ng.686openalex-snapshot

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

inferredcites →https://doi.org/10.1038/ng.75openalex-snapshot

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

inferredcites →https://doi.org/10.1038/ng.866openalex-snapshot

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

inferredcites →https://doi.org/10.1038/ng.920openalex-snapshot

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

inferredcites →https://doi.org/10.1038/sj.ejcn.1601993openalex-snapshot

New bioimpedance analysis system: improved phenotyping with whole-body analysis

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Genome-wide association studies in East Asians identify new loci for waist-hip ratio and waist circumference

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Health Effects of Overweight and Obesity in 195 Countries over 25 Years

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GenABEL: an R library for genome-wide association analysis

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METAL: fast and efficient meta-analysis of genomewide association scans

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PhenoScanner: a database of human genotype–phenotype associations

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Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

inferredcites →https://doi.org/10.1093/nar/gkg509openalex-snapshot

SIFT: predicting amino acid changes that affect protein function

inferredcites →https://doi.org/10.1093/nar/gkr917openalex-snapshot

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

inferredcites →https://doi.org/10.1093/nar/gkw1133openalex-snapshot

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

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Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF‐β signaling as primary targets

inferredcites →https://doi.org/10.1097/cej.0b013e3283457274openalex-snapshot

Meta and pooled analyses of FGFR4 Gly388Arg polymorphism as a cancer prognostic factor

inferredcites →https://doi.org/10.1101/074450openalex-snapshot

Local genetic effects on gene expression across 44 human tissues

inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot

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inferredcites →https://doi.org/10.1126/science.1141634openalex-snapshot

A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity

inferredcites →https://doi.org/10.1146/annurev-nutr-071816-064827openalex-snapshot

Genetic Basis for Sex Differences in Obesity and Lipid Metabolism

inferredcites →https://doi.org/10.1146/annurev.cellbio.042308.113334openalex-snapshot

The Diverse Functions of Oxysterol-Binding Proteins

inferredcites →https://doi.org/10.1186/1471-2105-11-288openalex-snapshot

GWAMA: software for genome-wide association meta-analysis

inferredcites →https://doi.org/10.1186/s13059-015-0676-3openalex-snapshot

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family

inferredcites →https://doi.org/10.1210/edrv-14-1-72openalex-snapshot

Genetic and Nongenetic Determinants of Regional Fat Distribution

inferredcites →https://doi.org/10.1210/edrv.21.6.0415openalex-snapshot

Subcutaneous and Visceral Adipose Tissue: Their Relation to the Metabolic Syndrome

inferredcites →https://doi.org/10.1371/journal.pgen.0030115openalex-snapshot

Genome-Wide Association Scan Shows Genetic Variants in the FTO Gene Are Associated with Obesity-Related Traits

inferredcites →https://doi.org/10.1371/journal.pgen.1002695openalex-snapshot

Genome-Wide Association for Abdominal Subcutaneous and Visceral Adipose Reveals a Novel Locus for Visceral Fat in Women

inferredcites →https://doi.org/10.1371/journal.pgen.1003500openalex-snapshot

Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits

inferredcites →https://doi.org/10.1371/journal.pgen.1005378openalex-snapshot

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

inferredcites →https://doi.org/10.17863/cam.12021openalex-snapshot

Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

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Learning Bayesian Networks with the bnlearn R Package

inferredcites →https://doi.org/10.18637/jss.v035.i12openalex-snapshot

plink: AnRPackage for Linking Mixed-Format Tests Using IRT-Based Methods

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Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease

inferredcites →https://doi.org/10.25405/ncl.34240818openalex-snapshot

Defining the role of common variation in the genomic and biological architecture of adult human height

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On the Adaptive Control of the False Discovery Rate in Multiple Testing With Independent Statistics

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