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Uterine progesterone signaling is a target for metformin therapy in PCOS-like rats
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/0026-0495(92)90175-aopenalex-snapshot
Hyperinsulinemia and human chorionic gonadotropin synergistically promote the growth of ovarian follicular cysts in rats
inferredcites →https://doi.org/10.1016/j.bbacli.2015.08.004openalex-snapshot
Lack of cyclical fluctuations of endometrial GLUT4 expression in women with polycystic ovary syndrome: Evidence for direct regulation of GLUT4 by steroid hormones
inferredcites →https://doi.org/10.1016/j.bpobgyn.2016.03.008openalex-snapshot
Polycystic ovary syndrome: Endometrial markers
inferredcites →https://doi.org/10.1016/j.ebiom.2017.03.023openalex-snapshot
Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary Syndrome
inferredcites →https://doi.org/10.1016/j.fertnstert.2005.09.053openalex-snapshot
Evaluation of steroid receptors, coregulators, and molecules associated with uterine receptivity in secretory endometria from untreated women with polycystic ovary syndrome
inferredcites →https://doi.org/10.1016/j.fertnstert.2010.01.049openalex-snapshot
Reduced percentage of natural killer cells associated with impaired cytokine network in the secretory endometrium of infertile women with polycystic ovary syndrome
inferredcites →https://doi.org/10.1016/j.fertnstert.2010.11.036openalex-snapshot
Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis
inferredcites →https://doi.org/10.1016/j.mce.2010.02.029openalex-snapshot
Spatiotemporal expression of androgen receptors in the female rat brain during the oestrous cycle and the impact of exogenous androgen administration: A comparison with gonadally intact males
inferredcites →https://doi.org/10.1016/j.mce.2012.10.007openalex-snapshot
Rodent models of polycystic ovary syndrome
inferredcites →https://doi.org/10.1016/j.ygyno.2012.01.003openalex-snapshot
Oncologic and Reproductive outcomes with progestin therapy in women with endometrial hyperplasia and grade 1 Adenocarcinoma: A systematic review
inferredcites →https://doi.org/10.1016/s0002-9378(16)33500-1openalex-snapshot
Dating the endometrial biopsy
inferredcites →https://doi.org/10.1016/s0026-0495(00)90110-0openalex-snapshot
Synergistic effects of insulin-like growth factor-I and human chorionic gonadotropin in the rat ovary
inferredcites →https://doi.org/10.1016/s0026-0495(99)90196-8openalex-snapshot
Insulin has a biphasic effect on the ability of human chorionic gonadotropin to induce ovarian cysts in the rat
inferredcites →https://doi.org/10.1038/ijo.2016.154openalex-snapshot
Proinflammatory environment and role of TNF-α in endometrial function of obese women having polycystic ovarian syndrome
inferredcites →https://doi.org/10.1038/nrendo.2010.217openalex-snapshot
Polycystic ovary syndrome: etiology, pathogenesis and diagnosis
inferredcites →https://doi.org/10.1038/nrendo.2016.116openalex-snapshot
Fertile ground: human endometrial programming and lessons in health and disease
inferredcites →https://doi.org/10.1038/nri3495openalex-snapshot
Mitogen-activated protein kinases in innate immunity
inferredcites →https://doi.org/10.1038/srep14994openalex-snapshot
Functional microarray analysis of differentially expressed genes in granulosa cells from women with polycystic ovary syndrome related to MAPK/ERK signaling
inferredcites →https://doi.org/10.1038/srep30679openalex-snapshot
Molecular characterization of insulin resistance and glycolytic metabolism in the rat uterus
inferredcites →https://doi.org/10.1042/bj20100323openalex-snapshot
Mechanisms and functions of p38 MAPK signalling
inferredcites →https://doi.org/10.1093/humrep/deg255openalex-snapshot
Immunocytochemical assessment of mitotic activity with an antibody to phosphorylated histone H3 in the macaque and human endometrium
inferredcites →https://doi.org/10.1093/humrep/dei351openalex-snapshot
Uterine effects of metformin administration in anovulatory women with polycystic ovary syndrome
inferredcites →https://doi.org/10.1093/humrep/del183openalex-snapshot
Expression of molecules associated with tissue homeostasis in secretory endometria from untreated women with polycystic ovary syndrome
inferredcites →https://doi.org/10.1093/humrep/des134openalex-snapshot
Expression of leukaemia inhibitory factor and interleukin 15 in endometrium of women with recurrent implantation failure after IVF; correlation with the number of endometrial natural killer cells
inferredcites →https://doi.org/10.1093/humrep/dev055openalex-snapshot
Endometrial stromal fibroblasts from women with polycystic ovary syndrome have impaired progesterone-mediated decidualization, aberrant cytokine profiles and promote enhanced immune cell migration in vitro
inferredcites →https://doi.org/10.1093/humupd/dmi005openalex-snapshot
Combined oral contraceptives in the treatment of polycystic ovary syndrome
inferredcites →https://doi.org/10.1093/humupd/dmu056openalex-snapshot
Role of nuclear progesterone receptor isoforms in uterine pathophysiology
inferredcites →https://doi.org/10.1093/humupd/dmv025openalex-snapshot
Metformin and lifestyle modification in polycystic ovary syndrome: systematic review and meta-analysis
inferredcites →https://doi.org/10.1093/humupd/dmv029openalex-snapshot
Pregnancy complications in women with polycystic ovary syndrome
inferredcites →https://doi.org/10.1093/humupd/dmv063openalex-snapshot
Metformin and lifestyle modification in polycystic ovary syndrome: systematic review and meta-analysis
inferredcites →https://doi.org/10.1093/molehr/8.5.465openalex-snapshot
Expression of MAPkinases (Erk1/2) during decidualization in the rat: regulation by progesterone and nitric oxide
inferredcites →https://doi.org/10.1093/molehr/gax015openalex-snapshot
hCG activates Epac-Erk1/2 signaling regulating Progesterone Receptor expression and function in human endometrial stromal cells
inferredcites →https://doi.org/10.1111/aji.12473openalex-snapshot
Progesterone‐Regulated Endometrial Factors Controlling Implantation
inferredcites →https://doi.org/10.1111/aji.12552openalex-snapshot
Progestin suppressed inflammation and cell viability of tumor necrosis factor‐α‐stimulated endometriotic stromal cells
inferredcites →https://doi.org/10.1111/cen.12951openalex-snapshot
Serum levels of TSP ‐1, NF ‐κB and TGF ‐β1 in polycystic ovarian syndrome ( PCOS ) patients in northern China suggest PCOS is associated with chronic inflammation
inferredcites →https://doi.org/10.1111/j.0105-2896.2005.00287.xopenalex-snapshot
Innate and adaptive immunity in female genital tract: cellular responses and interactions
inferredcites →https://doi.org/10.1128/mcb.00654-06openalex-snapshot
Steroid Receptor Coactivator 2 Is Critical for Progesterone-Dependent Uterine Function and Mammary Morphogenesis in the Mouse
inferredcites →https://doi.org/10.1152/ajpendo.00434.2005openalex-snapshot
Differential expression of uterine calcium transporter 1 and plasma membrane Ca2+ATPase 1b during rat estrous cycle
inferredcites →https://doi.org/10.1172/jci31622openalex-snapshot
FKBP52 deficiency–conferred uterine progesterone resistance is genetic background and pregnancy stage specific
inferredcites →https://doi.org/10.1177/1933719113519169openalex-snapshot
Histomorphometric Analysis and Markers of Endometrial Receptivity Embryonic Implantation in Women With Polycystic Ovary Syndrome During the Treatment With Progesterone
inferredcites →https://doi.org/10.1186/1423-0127-21-2openalex-snapshot
Endometrial progesterone resistance and PCOS
inferredcites →https://doi.org/10.1186/1756-9966-33-41openalex-snapshot
Direct effects of metformin in the endometrium: a hypothetical mechanism for the treatment of women with PCOS and endometrial carcinoma
inferredcites →https://doi.org/10.1210/en.137.4.1226openalex-snapshot
RU486 on an estrogen background blocks the rise in serum follicle- stimulating hormone induced by antiserum to inhibin or ovariectomy
inferredcites →https://doi.org/10.1210/er.2014-1045openalex-snapshot
Cyclic Decidualization of the Human Endometrium in Reproductive Health and Failure
inferredcites →https://doi.org/10.1210/er.2015-1104openalex-snapshot
The Pathogenesis of Polycystic Ovary Syndrome (PCOS): The Hypothesis of PCOS as Functional Ovarian Hyperandrogenism Revisited
inferredcites →https://doi.org/10.1210/jc.2008-1612openalex-snapshot
Transcriptional Profiling with a Pathway-Oriented Analysis Identifies Dysregulated Molecular Phenotypes in the Endometrium of Patients with Polycystic Ovary Syndrome
inferredcites →https://doi.org/10.1210/jc.2010-0603openalex-snapshot
MUC1 as a Discriminator between Endometrium from Fertile and Infertile Patients with PCOS and Endometriosis
inferredcites →https://doi.org/10.1210/jc.2010-2600openalex-snapshot
Progesterone Resistance in PCOS Endometrium: A Microarray Analysis in Clomiphene Citrate-Treated and Artificial Menstrual Cycles
inferredcites →https://doi.org/10.1210/jc.2013-1923openalex-snapshot
Mesenchymal Stem/Progenitors and Other Endometrial Cell Types From Women With Polycystic Ovary Syndrome (PCOS) Display Inflammatory and Oncogenic Potential
inferredcites →https://doi.org/10.1210/jc.2014-2419openalex-snapshot
Up-Regulated Expression of WNT5a Increases Inflammation and Oxidative Stress via PI3K/AKT/NF-κB Signaling in the Granulosa Cells of PCOS Patients
inferredcites →https://doi.org/10.1210/jc.86.3.1126openalex-snapshot
Insulin Reduction with Metformin Increases Luteal Phase Serum Glycodelin and Insulin-Like Growth Factor-Binding Protein 1 Concentrations and Enhances Uterine Vascularity and Blood Flow in the Polycystic Ovary Syndrome
inferredcites →https://doi.org/10.1210/jcem.86.3.7295openalex-snapshot
Insulin Reduction with Metformin Increases Luteal Phase Serum Glycodelin and Insulin-Like Growth Factor-Binding Protein 1 Concentrations and Enhances Uterine Vascularity and Blood Flow in the Polycystic Ovary Syndrome1
inferredcites →https://doi.org/10.1210/me.2004-0178openalex-snapshot
Alterations in Mitogen-Activated Protein Kinase Kinase and Extracellular Regulated Kinase Signaling in Theca Cells Contribute to Excessive Androgen Production in Polycystic Ovary Syndrome
inferredcites →https://doi.org/10.1210/me.2006-0024openalex-snapshot
FK506-Binding Protein 52 Is Essential to Uterine Reproductive Physiology Controlled by the Progesterone Receptor A Isoform
inferredcites →https://doi.org/10.1371/journal.pone.0075282openalex-snapshot
Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway Is Required for Endometrial Decidualization in Mice and Human
inferredcites →https://doi.org/10.1530/rep-14-0435openalex-snapshot
Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome
inferredcites →https://doi.org/10.1621/nrs.05011openalex-snapshot
Steroid Receptor Coactivator 2 is Required for Female Fertility and Mammary Morphogenesis: Insights from the Mouse, Relevance to the Human
inferredcites →https://doi.org/10.18632/oncotarget.24477openalex-snapshot
Hyperandrogenism and insulin resistance contribute to hepatic steatosis and inflammation in female rat liver
inferredcites →https://doi.org/10.7150/ijbs.13109openalex-snapshot
Regulation of Androgen Receptor Expression Alters AMPK Phosphorylation in the Endometrium: In Vivo and In Vitro Studies in Women with Polycystic Ovary Syndrome
inferredcites →https://doi.org/10.7150/jca.8009openalex-snapshot
Combination of Diane-35 and Metformin to Treat Early Endometrial Carcinoma in PCOS Women with Insulin Resistance
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/1873-3468.14289openalex-snapshot
Overactivation of the androgen receptor exacerbates gravid uterine ferroptosis via interaction with and suppression of the NRF2 defense signaling pathway
inferred← citeshttps://doi.org/10.1007/s43032-024-01755-wopenalex-snapshot
Comparing the Effect of Heat Therapy and Mitochondrial-Targeted Antioxidants in Polycystic Ovarian Syndrome Phenotype Induced by Junk Food Consumption
inferred← citeshttps://doi.org/10.20944/preprints201903.0271.v1openalex-snapshot
Perturbed Ovarian and Uterine Glucocorticoid Receptor Signaling Accompanies the Balanced Regulation of Mitochondrial Function and NFκB-Mediated Inflammation under Conditions of Hyperandrogenism and Insulin Resistance
inferred← citeshttps://doi.org/10.54319/jjbs/150510openalex-snapshot
Insight Towards Induction of Reproductive-Metabolic Phenotypes of Polycystic Ovarian Syndrome
inferred← citeshttps://doi.org/10.7150/ijbs.31425openalex-snapshot
Differential Expression Patterns of Glycolytic Enzymes and Mitochondria-Dependent Apoptosis in PCOS Patients with Endometrial Hyperplasia, an Early Hallmark of Endometrial Cancer, In Vivo and the Impact of Metformin In Vitro
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