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Comparative transcriptomics reveals a conserved Bacterial Adaptive Phage Response (BAPR) to viral predation

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Bacterial cell‐to‐cell signaling promotes the evolution of resistance to parasitic bacteriophages
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The genome of bacteriophage φKZ of Pseudomonas aeruginosa
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Preparing cDNA Libraries from Lytic Phage-Infected Cells for Whole Transcriptome Analysis by RNA-Seq
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Bacteriophage defence systems in lactic acid bacteria
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The glycine cleavage system: Composition, reaction mechanism, and physiological significance
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A giant Pseudomonas phage from Poland
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The Pseudomonas aeruginosa 4-Quinolone Signal Molecules HHQ and PQS Play Multifunctional Roles in Quorum Sensing and Iron Entrapment
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Manipulation of cellular syntheses and the nature of viruses: The virocell concept
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Parasite Exposure Drives Selective Evolution of Constitutive versus Inducible Defense
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The biology of restriction and anti-restriction
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Phage abortive infection in lactococci: variations on a theme
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The Pseudomonas aeruginosa toxin L-2-amino-4-methoxy-trans-3-butenoic acid inhibits growth and induces encystment in Acanthamoeba castellanii
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The Pseudomonas aeruginosa quinolone quorum sensing signal alters the multicellular behaviour of Pseudomonas putida KT2440
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α-Vinylic amino acids: occurrence, asymmetric synthesis, and biochemical mechanisms
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Genomes of “phiKMV-like viruses” of Pseudomonas aeruginosa contain localized single-strand interruptions
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Molecular and physiological analysis of three Pseudomonas aeruginosa phages belonging to the “N4-like viruses”
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Host RNA polymerase inhibitors encoded by ϕKMV-like phages of pseudomonas
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Bacteriophage Host Range and Bacterial Resistance
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Chapter 2 RNA Processing and Decay in Bacteriophage T4
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Dual control of hydrogen cyanide biosynthesis by the global activator GacA in Pseudomonas aeruginosa PAO1
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Factor Fraction required for the Synthesis of Bacteriophage Qβ-RNA
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Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
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The virocell concept and environmental microbiology
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Transcriptome dynamics of a broad host-range cyanophage and its hosts
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High coverage metabolomics analysis reveals phage-specific alterations to Pseudomonas aeruginosa physiology during infection
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Regulation of infection efficiency in a globally abundant marine Bacteriodetes virus
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Comparative transcriptomics analyses reveal the conservation of an ancestral infectious strategy in two bacteriophage genera
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Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution
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DNA-guided DNA interference by a prokaryotic Argonaute
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CRISPR-Cas immunity in prokaryotes
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Pseudomonas predators: understanding and exploiting phage–host interactions
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Hfq and its constellation of RNA
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Hfq, a new chaperoning role: binding to messenger RNA determines access for small RNA regulator
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Intrinsic, adaptive and acquired antimicrobial resistance in Gram-negative bacteria
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Alkaline shock induces the Bacillus subtilisσW regulon
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The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density‐dependency of the quorum sensing hierarchy, regulates rhl‐dependent genes at the onset of stationary phase and can be produced in the absence of LasR
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Phage therapy: The peculiar kinetics of self-replicating pharmaceuticals
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Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication
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The Sm domain is an ancient RNA-binding motif with oligo(U) specificity
inferredcites →https://doi.org/10.1073/pnas.1502025112openalex-snapshot
Type IV pili mechanochemically regulate virulence factors in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1073/pnas.1617415113openalex-snapshot
Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system
inferredcites →https://doi.org/10.1073/pnas.96.26.15202openalex-snapshot
Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1074/jbc.m112.376368openalex-snapshot
The Second Type VI Secretion System of Pseudomonas aeruginosa Strain PAO1 Is Regulated by Quorum Sensing and Fur and Modulates Internalization in Epithelial Cells
inferredcites →https://doi.org/10.1093/nar/gkq869openalex-snapshot
Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes
inferredcites →https://doi.org/10.1093/nar/gkt1419openalex-snapshot
A widespread bacteriophage abortive infection system functions through a Type IV toxin–antitoxin mechanism
inferredcites →https://doi.org/10.1093/nar/gkv1095openalex-snapshot
A non-canonical multisubunit RNA polymerase encoded by a giant bacteriophage
inferredcites →https://doi.org/10.1093/nar/gkv1227openalex-snapshot
Enhanced annotations and features for comparing thousands of Pseudomonas genomes in the Pseudomonas genome database
inferredcites →https://doi.org/10.1097/00000658-196701000-00014openalex-snapshot
Cyanide Production by Pseudomonas Aeruginosa
inferredcites →https://doi.org/10.1099/00221287-13-3-572openalex-snapshot
Genetic Recombination in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1099/mic.0.063065-0openalex-snapshot
The role of two Pseudomonas aeruginosa anthranilate synthases in tryptophan and quorum signal production
inferredcites →https://doi.org/10.1101/gad.7.1.161openalex-snapshot
Elongation factor NusG interacts with termination factor rho to regulate termination and antitermination of transcription.
inferredcites →https://doi.org/10.1107/s0907444904030008openalex-snapshot
Structure ofPseudomonas aeruginosaHfq protein
inferredcites →https://doi.org/10.1111/j.1365-2036.2006.03036.xopenalex-snapshot
Systematic review: are antibiotics detrimental or beneficial for the treatment of patients with Escherichia coli O157:H7 infection?
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Phage‐exclusion enzymes: a bonanza of biochemical and cell biology reagents?
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MicroReview: The bacterial Sm‐like protein Hfq: a key player in RNA transactions
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Hfq‐dependent alterations of the transcriptome profile and effects on quorum sensing in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1111/j.1365-2958.2009.06782.xopenalex-snapshot
The GacS/GacA signal transduction system of Pseudomonas aeruginosa acts exclusively through its control over the transcription of the RsmY and RsmZ regulatory small RNAs
inferredcites →https://doi.org/10.1111/j.1365-2958.2011.07620.xopenalex-snapshot
The small RNA PhrS stimulates synthesis of the Pseudomonas aeruginosa quinolone signal
inferredcites →https://doi.org/10.1111/j.1462-2920.2009.02030.xopenalex-snapshot
Comparative analysis of the widespread and conserved PB1‐like viruses infecting Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1111/j.1462-2920.2009.02101.xopenalex-snapshot
Roles of viruses in the environment
inferredcites →https://doi.org/10.1111/j.1462-2920.2010.02214.xopenalex-snapshot
Transcriptomic analysis reveals a global alkyl‐quinolone‐independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts
inferredcites →https://doi.org/10.1111/j.1574-6968.2009.01640.xopenalex-snapshot
The adsorption of Pseudomonas aeruginosa bacteriophage φKMV is dependent on expression regulation of type IV pili genes
inferredcites →https://doi.org/10.1111/j.1758-2229.2012.00395.xopenalex-snapshot
The P seudomonas aeruginosa antimetabolite L ‐2‐amino‐4‐methoxy‐ trans ‐3‐butenoic acid inhibits growth of E rwinia amylovora and acts as a seed germination‐arrest factor
inferredcites →https://doi.org/10.1128/aac.42.8.1938openalex-snapshot
Characterization of the MexC-MexD-OprJ Multidrug Efflux System in Δ mexA-mexB-oprM Mutants of Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1128/aac.44.12.3322-3327.2000openalex-snapshot
Substrate Specificities of MexAB-OprM, MexCD-OprJ, and MexXY-OprM Efflux Pumps in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1128/aem.01197-13openalex-snapshot
Lytic Infection of Lactococcus lactis by Bacteriophages Tuc2009 and c2 Triggers Alternative Transcriptional Host Responses
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The atu and liu Clusters Are Involved in the Catabolic Pathways for Acyclic Monoterpenes and Leucine in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1128/iai.67.7.3625-3630.1999openalex-snapshot
Pseudomonas aeruginosa Gene Products PilT and PilU Are Required for Cytotoxicity In Vitro and Virulence in a Mouse Model of Acute Pneumonia
inferredcites →https://doi.org/10.1128/jb.00010-09openalex-snapshot
The Pseudomonas aeruginosa Pyochelin-Iron Uptake Pathway and Its Metal Specificity
inferredcites →https://doi.org/10.1128/jb.00112-10openalex-snapshot
Characterization of thePseudomonas aeruginosaTranscriptional Response to Phenylalanine and Tyrosine
inferredcites →https://doi.org/10.1128/jb.00831-06openalex-snapshot
Genomic Analysis of Pseudomonas aeruginosa Phages LKD16 and LKA1: Establishment of the φKMV Subgroup within the T7 Supergroup
inferredcites →https://doi.org/10.1128/jb.01034-13openalex-snapshot
Identification of the Alternative Sigma Factor SigX Regulon and Its Implications for Pseudomonas aeruginosa Pathogenicity
inferredcites →https://doi.org/10.1128/jb.01441-07openalex-snapshot
The Genome and Structural Proteome of YuA, a New Pseudomonas aeruginosa Phage Resembling M6
inferredcites →https://doi.org/10.1128/jb.01515-09openalex-snapshot
Genome Diversity of Pseudomonas aeruginosa PAO1 Laboratory Strains
inferredcites →https://doi.org/10.1128/jb.02205-12openalex-snapshot
Gene PA2449 Is Essential for Glycine Metabolism and Pyocyanin Biosynthesis in Pseudomonas aeruginosa PAO1
inferredcites →https://doi.org/10.1128/jb.05074-11openalex-snapshot
Identification of C 4 -Dicarboxylate Transport Systems in Pseudomonas aeruginosaPAO1
inferredcites →https://doi.org/10.1128/jb.182.24.6940-6949.2000openalex-snapshot
Transcriptional Control of the Hydrogen Cyanide Biosynthetic Genes hcnABC by the Anaerobic Regulator ANR and the Quorum-Sensing Regulators LasR and RhlR in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1128/jb.183.19.5617-5631.2001openalex-snapshot
Global Analysis of the General Stress Response of Bacillus subtilis
inferredcites →https://doi.org/10.1128/jb.183.21.6207-6214.2001openalex-snapshot
Pseudomonas aeruginosa PAO1 Kills Caenorhabditis elegans by Cyanide Poisoning
inferredcites →https://doi.org/10.1128/jb.184.23.6472-6480.2002openalex-snapshot
Functions Required for Extracellular Quinolone Signaling by Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1128/jb.184.23.6481-6489.2002openalex-snapshot
Autolysis and Autoaggregation in Pseudomonas aeruginosa Colony Morphology Mutants
inferredcites →https://doi.org/10.1128/jb.64.6.773-781.1952openalex-snapshot
UTILIZATION OF CARBOHYDRATES BY PSEUDOMONAS AERUGINOSA
inferredcites →https://doi.org/10.1128/jvi.00065-06openalex-snapshot
Global Changes in Cellular Gene Expression during Bacteriophage PRD1 Infection
inferredcites →https://doi.org/10.1128/jvi.00275-11openalex-snapshot
Genetic Response to Bacteriophage Infection in Lactococcus lactis Reveals a Four-Strand Approach Involving Induction of Membrane Stress Proteins, d -Alanylation of the Cell Wall, Maintenance of Proton Motive Force, and Energy Conservation
inferredcites →https://doi.org/10.1128/jvi.01347-14openalex-snapshot
Development of Giant Bacteriophage ϕKZ Is Independent of the Host Transcription Apparatus
inferredcites →https://doi.org/10.1128/jvi.01930-07openalex-snapshot
Global Transcriptional Responses of Pseudomonas aeruginosa to Phage PRR1 Infection
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Transcription During the Development of Bacteriophage φ29: Production of Host-and φ29-Specific Ribonucleic Acid
inferredcites →https://doi.org/10.1128/mbio.00061-13openalex-snapshot
A Multifaceted Study of Pseudomonas aeruginosa Shutdown by Virulent Podovirus LUZ19
inferredcites →https://doi.org/10.1128/mbio.00749-15openalex-snapshot
The Pseudomonas aeruginosa Transcriptional Landscape Is Shaped by Environmental Heterogeneity and Genetic Variation
inferredcites →https://doi.org/10.1128/mbio.02312-16openalex-snapshot
Identification of a Pseudomonas aeruginosa PAO1 DNA Methyltransferase, Its Targets, and Physiological Roles
inferredcites →https://doi.org/10.1128/mmbr.43.2.199-223.1979openalex-snapshot
Shutoff of host macromolecular synthesis after T-even bacteriophage infection
inferredcites →https://doi.org/10.1128/mmbr.67.1.86-156.2003openalex-snapshot
Bacteriophage T4 Genome
inferredcites →https://doi.org/10.1128/msphere.00020-16openalex-snapshot
GcsR, a TyrR-Like Enhancer-Binding Protein, Regulates Expression of the Glycine Cleavage System in Pseudomonas aeruginosa PAO1
inferredcites →https://doi.org/10.1146/annurev-micro-092611-150055openalex-snapshot
Pseudomonas aeruginosa Twitching Motility: Type IV Pili in Action
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1371/journal.pgen.1003454openalex-snapshot
Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands
inferredcites →https://doi.org/10.1371/journal.pgen.1004440openalex-snapshot
Regulation of Hfq by the RNA CrcZ in Pseudomonas aeruginosa Carbon Catabolite Repression
inferredcites →https://doi.org/10.1371/journal.pgen.1006134openalex-snapshot
Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1371/journal.pone.0024310openalex-snapshot
MexEF-OprN Efflux Pump Exports the Pseudomonas Quinolone Signal (PQS) Precursor HHQ (4-hydroxy-2-heptylquinoline)
inferredcites →https://doi.org/10.1371/journal.ppat.1000166openalex-snapshot
The Pseudomonas Quinolone Signal (PQS) Balances Life and Death in Pseudomonas aeruginosa Populations
inferredcites →https://doi.org/10.1371/journal.ppat.1004744openalex-snapshot
Elucidation of Sigma Factor-Associated Networks in Pseudomonas aeruginosa Reveals a Modular Architecture with Limited and Function-Specific Crosstalk
inferredcites →https://doi.org/10.15252/embj.201489455openalex-snapshot
BREX is a novel phage resistance system widespread in microbial genomes
inferredcites →https://doi.org/10.2174/138920110790725410openalex-snapshot
Phage Therapy Pharmacology
inferredcites →https://doi.org/10.3389/fmicb.2015.00170openalex-snapshot
The Pseudomonas aeruginosa antimetabolite L -2-amino-4-methoxy-trans-3-butenoic acid (AMB) is made from glutamate and two alanine residues via a thiotemplate-linked tripeptide precursor
inferredcites →https://doi.org/10.3390/v8040111openalex-snapshot
RNA-Sequencing Reveals the Progression of Phage-Host Interactions between φR1-37 and Yersinia enterocolitica
inferredcites →https://doi.org/10.5962/bhl.title.6966openalex-snapshot
Bacteriophages
inferredcites →https://doi.org/10.7554/elife.16413openalex-snapshot
Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Early Transcriptome of Pseudomonas aeruginosa PAO1 Infected With vB_Pae_QDWS, a Short‐Latent Lytic Phage
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Metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation
inferred← citeshttps://doi.org/10.1016/j.coviro.2021.12.004openalex-snapshot
Digital phagograms: predicting phage infectivity through a multilayer machine learning approach
inferred← citeshttps://doi.org/10.1016/j.molcel.2020.12.011openalex-snapshot
A phage-encoded anti-activator inhibits quorum sensing in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1016/j.tim.2019.10.007openalex-snapshot
Steering Phages to Combat Bacterial Pathogens
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Phage therapy
inferred← citeshttps://doi.org/10.1080/15476286.2020.1827785openalex-snapshot
Introducing differential RNA-seq mapping to track the early infection phase for Pseudomonas phage ɸKZ
inferred← citeshttps://doi.org/10.1080/15476286.2023.2216065openalex-snapshot
Impact of phage predation on P. aeruginosa adhered to human airway epithelium: major transcriptomic changes in metabolism and virulence-associated genes
inferred← citeshttps://doi.org/10.1093/nar/gkab1210openalex-snapshot
Type I CRISPR-Cas provides robust immunity but incomplete attenuation of phage-induced cellular stress
inferred← citeshttps://doi.org/10.1101/2025.04.11.648453openalex-snapshot
Overlooked signals: Highly stable quorum sensing molecule in phage lysates induces quorum sensing response
inferred← citeshttps://doi.org/10.1101/406421openalex-snapshot
Genomic, transcriptomic, and structural analysis of Pseudomonas virus PA5oct highlights the molecular complexity among Jumbo phages
inferred← citeshttps://doi.org/10.1111/1462-2920.14979openalex-snapshot
Integrative omics analysis of Pseudomonas aeruginosa virus PA5oct highlights the molecular complexity of jumbo phages
inferred← citeshttps://doi.org/10.1111/1751-7915.13728openalex-snapshot
Bacteriophage‐mediated interference of the c‐di‐GMP signalling pathway in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1111/mmi.15202openalex-snapshot
Inhibition of PQS signaling by the Pf bacteriophage protein PfsE enhances viral replication in Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.1128/jb.00383-19openalex-snapshot
PQS Produced by the Pseudomonas aeruginosa Stress Response Repels Swarms Away from Bacteriophage and Antibiotics
inferred← citeshttps://doi.org/10.1128/jb.00557-21openalex-snapshot
Phage Infection Restores PQS Signaling and Enhances Growth of a Pseudomonas aeruginosa lasI Quorum-Sensing Mutant
inferred← citeshttps://doi.org/10.1128/jb.00568-19openalex-snapshot
PQS Signaling for More than a Quorum: the Collective Stress Response Protects Healthy Pseudomonas aeruginosa Populations
inferred← citeshttps://doi.org/10.1128/jb.00687-20openalex-snapshot
The Impact of Quorum Sensing on the Modulation of Phage-Host Interactions
inferred← citeshttps://doi.org/10.1128/msystems.00358-20openalex-snapshot
A Family of Viral Satellites Manipulates Invading Virus Gene Expression and Can Affect Cholera Toxin Mobilization
inferred← citeshttps://doi.org/10.1186/s12859-020-03730-zopenalex-snapshot
SAPPHIRE: a neural network based classifier for σ70 promoter prediction in Pseudomonas
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Bacteriophage-Insensitive Mutants of Antimicrobial-Resistant Salmonella Enterica are Altered in their Tetracycline Resistance and Virulence in Caco-2 Intestinal Cells
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Expert Opinion on Three Phage Therapy Related Topics: Bacterial Phage Resistance, Phage Training and Prophages in Bacterial Production Strains
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Transcriptomic Analysis of the Campylobacter jejuni Response to T4-Like Phage NCTC 12673 Infection
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