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Increased PHGDH expression uncouples hair follicle cycle progression and promotes inappropriate melanin accumulation
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1 of the 47 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1158/0008-5472.can-16-0530 (notice 2024-09-04).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/gene.20180openalex-snapshot
Efficient method to generate single‐copy transgenic mice by site‐specific integration in embryonic stem cells
inferredcites →https://doi.org/10.1006/jtbi.2001.2474openalex-snapshot
The Follicular Automaton Model: Effect of Stochasticity and of Synchronization of Hair Cycles
inferredcites →https://doi.org/10.1007/s10549-010-0848-5openalex-snapshot
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis
inferredcites →https://doi.org/10.1007/s11060-012-1018-xopenalex-snapshot
Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1
inferredcites →https://doi.org/10.1016/0022-202x(93)90507-eopenalex-snapshot
Melanogenesis is coupled to murine anagen: Toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth
inferredcites →https://doi.org/10.1016/0092-8674(90)90696-copenalex-snapshot
Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
inferredcites →https://doi.org/10.1016/j.abb.2014.07.019openalex-snapshot
The roles of microphthalmia-associated transcription factor and pigmentation in melanoma
inferredcites →https://doi.org/10.1016/j.biocel.2010.03.023openalex-snapshot
Signaling pathways in melanosome biogenesis and pathology
inferredcites →https://doi.org/10.1016/j.cmet.2013.11.004openalex-snapshot
The Histone H3 Methyltransferase G9A Epigenetically Activates the Serine-Glycine Synthesis Pathway to Sustain Cancer Cell Survival and Proliferation
inferredcites →https://doi.org/10.1016/j.cmet.2016.06.014openalex-snapshot
Psat1-Dependent Fluctuations in α-Ketoglutarate Affect the Timing of ESC Differentiation
inferredcites →https://doi.org/10.1016/j.gep.2017.10.003openalex-snapshot
Characterization of a new, inducible transgenic mouse model with GFP expression in melanocytes and their precursors
inferredcites →https://doi.org/10.1016/j.jtbi.2012.05.027openalex-snapshot
A prototypic mathematical model of the human hair cycle
inferredcites →https://doi.org/10.1016/j.semcdb.2012.08.003openalex-snapshot
Hairy tale of signaling in hair follicle development and cycling
inferredcites →https://doi.org/10.1016/s0021-9258(18)62729-2openalex-snapshot
Studies on the Role of 3-Phosphoglycerate Dehydrogenase in the Regulation of Serine Biosynthesis in Rat Liver
inferredcites →https://doi.org/10.1023/a:1013986627504openalex-snapshot
Conditional gene expression in the respiratory epithelium of the mouse
inferredcites →https://doi.org/10.1023/a:1016632110931openalex-snapshot
Tet-system for the regulation of gene expression during embryonic development
inferredcites →https://doi.org/10.1038/35096009openalex-snapshot
The melanosome: membrane dynamics in black and white
inferredcites →https://doi.org/10.1038/416854aopenalex-snapshot
Dominant role of the niche in melanocyte stem-cell fate determination
inferredcites →https://doi.org/10.1038/990040openalex-snapshot
The temporal requirement for endothelin receptor-B signalling during neural crest development
inferredcites →https://doi.org/10.1038/jid.2010.335openalex-snapshot
Demodex folliculorum: Requirements for Understanding Its Role in Human Skin Disease
inferredcites →https://doi.org/10.1038/nature05659openalex-snapshot
Scratching the surface of skin development
inferredcites →https://doi.org/10.1038/nature09666openalex-snapshot
Interferon-γ links ultraviolet radiation to melanomagenesis in mice
inferredcites →https://doi.org/10.1038/nature10350openalex-snapshot
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
inferredcites →https://doi.org/10.1038/nature15726openalex-snapshot
Oxidative stress inhibits distant metastasis by human melanoma cells
inferredcites →https://doi.org/10.1038/ng.890openalex-snapshot
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
inferredcites →https://doi.org/10.1038/skinbio.2011.4openalex-snapshot
Determination of Melanin Synthetic Pathways
inferredcites →https://doi.org/10.1046/j.0022-202x.2001.01377.xopenalex-snapshot
A Comprehensive Guide for the Accurate Classification of Murine Hair Follicles in Distinct Hair Cycle Stages
inferredcites →https://doi.org/10.1046/j.1523-1747.1998.00417.xopenalex-snapshot
Do Hair Bulb Melanocytes Undergo Apotosis During Hair Follicle Regression (Catagen)?
inferredcites →https://doi.org/10.1073/pnas.152238499openalex-snapshot
Early restriction of peripheral and proximal cell lineages during formation of the lung
inferredcites →https://doi.org/10.1073/pnas.94.8.3789openalex-snapshot
Disruption of overlapping transcripts in the ROSA βgeo 26 gene trap strain leads to widespread expression of β-galactosidase in mouse embryos and hematopoietic cells
inferredcites →https://doi.org/10.1074/jbc.m610510200openalex-snapshot
Role of the Transcription Factor ATF4 in the Anabolic Actions of Insulin and the Anti-anabolic Actions of Glucocorticoids
inferredcites →https://doi.org/10.1093/jmcb/mjv005openalex-snapshot
mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration
inferredcites →https://doi.org/10.1097/igc.0b013e3182a0c068openalex-snapshot
Expression and Clinical Significance of Phosphoglycerate Dehydrogenase and Squamous Cell Carcinoma Antigen in Cervical Cancer
inferredcites →https://doi.org/10.1111/1523-1747.ep12362991openalex-snapshot
Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth.
inferredcites →https://doi.org/10.1111/j.1432-0436.2004.07209004.xopenalex-snapshot
In search of the “hair cycle clock”: a guided tour
inferredcites →https://doi.org/10.1111/j.1468-2494.2008.00456.xopenalex-snapshot
Human hair pigmentation – biological aspects
inferredcites →https://doi.org/10.1111/j.1600-0625.2007.00675.xopenalex-snapshot
Regulation of melanogenesis – controversies and new concepts
inferredcites →https://doi.org/10.1111/j.1600-0625.2012.01457.xopenalex-snapshot
The human hair follicle, a bistable organ?
inferredcites →https://doi.org/10.1111/j.1600-0749.2005.00288.xopenalex-snapshot
Tyrosinase maturation through the mammalian secretory pathway: bringing color to life
inferredcites →https://doi.org/10.1111/j.1755-148x.2009.00610.xopenalex-snapshot
Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function
inferredcites →https://doi.org/10.1111/j.1755-148x.2011.00832.xopenalex-snapshot
A genetically engineered mouse model with inducible GFP expression in melanocytes
inferredcites →https://doi.org/10.1126/science.1092436openalex-snapshot
Defining the Epithelial Stem Cell Niche in Skin
inferredcites →https://doi.org/10.1158/0008-5472.can-16-0530openalex-snapshot
RETRACTED: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis
inferredcites →https://doi.org/10.1186/s40170-015-0131-7openalex-snapshot
An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation
inferredcites →https://doi.org/10.1371/journal.pgen.1002573openalex-snapshot
Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis
inferredcites →https://doi.org/10.1590/s0365-05962013000100009openalex-snapshot
Mechanisms regulating melanogenesis*
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.02.015openalex-snapshot
Increased Serine Synthesis Provides an Advantage for Tumors Arising in Tissues Where Serine Levels Are Limiting
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