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Large-scale neuroimaging and genetic study reveals genetic architecture of brain white matter microstructure

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Estimating the Heritability of Structural and Functional Brain Connectivity in Families Affected by Attention-Deficit/Hyperactivity Disorder

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Association of White Matter Structure With Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder

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MaCH‐Admix: Genotype Imputation for Admixed Populations

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Fast robust automated brain extraction

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Intellectual abilities and white matter microstructure in development: A diffusion tensor imaging study

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Heritability of white matter microstructure in late middle age: A twin study of tract‐based fractional anisotropy and absolute diffusivity indices

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The basis of anisotropic water diffusion in the nervous system – a technical review

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Estimation of the Effective Self-Diffusion Tensor from the NMR Spin Echo

inferredcites →https://doi.org/10.1007/s11682-013-9269-5openalex-snapshot

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

inferredcites →https://doi.org/10.1016/j.ajhg.2010.11.011openalex-snapshot

GCTA: A Tool for Genome-wide Complex Trait Analysis

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Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data

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Genetics of ageing-related changes in brain white matter integrity – A review

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An Expanded View of Complex Traits: From Polygenic to Omnigenic

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Diffusion MRI of white matter microstructure development in childhood and adolescence: Methods, challenges and progress

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Psychiatric Genomics Consortium: Past And Present

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Beyond a bigger brain: Multivariable structural brain imaging and intelligence

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The use of polygenic risk scores to identify phenotypes associated with genetic risk of bipolar disorder and depression: A systematic review

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Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data

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Heritability of DTI and MTR in nine-year-old children

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BDNF gene effects on brain circuitry replicated in 455 twins

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FSL

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Quantitative tract-based white matter development from birth to age 2 years

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White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI

inferredcites →https://doi.org/10.1016/j.neuroimage.2013.07.064openalex-snapshot

Neuroimaging of the Philadelphia Neurodevelopmental Cohort

inferredcites →https://doi.org/10.1016/j.neuroimage.2014.06.021openalex-snapshot

Methodological considerations on tract-based spatial statistics (TBSS)

inferredcites →https://doi.org/10.1016/j.neuroimage.2015.02.021openalex-snapshot

Quantitative tract-based white matter heritability in twin neonates

inferredcites →https://doi.org/10.1016/j.neuroimage.2015.02.050openalex-snapshot

Heritability of fractional anisotropy in human white matter: A comparison of Human Connectome Project and ENIGMA-DTI data

inferredcites →https://doi.org/10.1016/j.neuroimage.2015.04.057openalex-snapshot

The Pediatric Imaging, Neurocognition, and Genetics (PING) Data Repository

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An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging

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Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank

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Effectiveness of regional DTI measures in distinguishing Alzheimer's disease, MCI, and normal aging

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White matter microstructural changes in adolescent anorexia nervosa including an exploratory longitudinal study

inferredcites →https://doi.org/10.1016/j.schres.2014.03.034openalex-snapshot

Genetic underpinnings of white matter ‘connectivity’: Heritability, risk, and heterogeneity in schizophrenia

inferredcites →https://doi.org/10.1017/s0080456800012163openalex-snapshot

XV.—The Correlation between Relatives on the Supposition of Mendelian Inheritance.

inferredcites →https://doi.org/10.1038/mp.2012.127openalex-snapshot

Brain-wide white matter tract integrity is associated with information processing speed and general intelligence

inferredcites →https://doi.org/10.1038/mp.2015.12openalex-snapshot

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

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An integrated map of genetic variation from 1,092 human genomes

inferredcites →https://doi.org/10.1038/ncomms13629openalex-snapshot

Ageing and brain white matter structure in 3,513 UK Biobank participants

inferredcites →https://doi.org/10.1038/ncomms8549openalex-snapshot

Large-scale genomics unveil polygenic architecture of human cortical surface area

inferredcites →https://doi.org/10.1038/ng.1108openalex-snapshot

Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs

inferredcites →https://doi.org/10.1038/ng.3211openalex-snapshot

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

inferredcites →https://doi.org/10.1038/ng.3404openalex-snapshot

Partitioning heritability by functional annotation using genome-wide association summary statistics

inferredcites →https://doi.org/10.1038/ng.3431openalex-snapshot

Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

inferredcites →https://doi.org/10.1038/ng.3941openalex-snapshot

Concepts, estimation and interpretation of SNP-based heritability

inferredcites →https://doi.org/10.1038/ng.608openalex-snapshot

Common SNPs explain a large proportion of the heritability for human height

inferredcites →https://doi.org/10.1038/ng.823openalex-snapshot

Genome partitioning of genetic variation for complex traits using common SNPs

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Multimodal population brain imaging in the UK Biobank prospective epidemiological study

inferredcites →https://doi.org/10.1038/nrg.2016.142openalex-snapshot

Dissecting the genetics of complex traits using summary association statistics

inferredcites →https://doi.org/10.1038/nrg.2017.101openalex-snapshot

Genetic architecture: the shape of the genetic contribution to human traits and disease

inferredcites →https://doi.org/10.1038/nrg2322openalex-snapshot

Heritability in the genomics era — concepts and misconceptions

inferredcites →https://doi.org/10.1038/nrg910openalex-snapshot

Beyond Mendel: an evolving view of human genetic disease transmission

inferredcites →https://doi.org/10.1038/s41588-018-0269-7openalex-snapshot

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

inferredcites →https://doi.org/10.1073/pnas.1415603112openalex-snapshot

Massively expedited genome-wide heritability analysis (MEGHA)

inferredcites →https://doi.org/10.1073/pnas.1604658114openalex-snapshot

Common and heritable components of white matter microstructure predict cognitive function at 1 and 2 y

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PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

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circlize implements and enhances circular visualization in R

inferredcites →https://doi.org/10.1093/cercor/bhy157openalex-snapshot

Heritability of Regional Brain Volumes in Large-Scale Neuroimaging and Genetic Studies

inferredcites →https://doi.org/10.1101/203257openalex-snapshot

Polygenic risk scores applied to a single cohort reveal pleiotropy among hundreds of human phenotypes

inferredcites →https://doi.org/10.1111/1467-9868.00346openalex-snapshot

A Direct Approach to False Discovery Rates

inferredcites →https://doi.org/10.1111/j.2517-6161.1995.tb02031.xopenalex-snapshot

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

inferredcites →https://doi.org/10.1146/annurev-clinpsy-032210-104507openalex-snapshot

Diffusion Imaging, White Matter, and Psychopathology

inferredcites →https://doi.org/10.1176/appi.ajp.2017.17030283openalex-snapshot

Psychiatric Genomics: An Update and an Agenda

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Leveraging functional annotations in genetic risk prediction for human complex diseases

inferredcites →https://doi.org/10.1371/journal.pgen.1003348openalex-snapshot

Power and Predictive Accuracy of Polygenic Risk Scores

inferredcites →https://doi.org/10.1371/journal.pgen.1003864openalex-snapshot

Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture

inferredcites →https://doi.org/10.1371/journal.pgen.1004269openalex-snapshot

Statistical Power to Detect Genetic (Co)Variance of Complex Traits Using SNP Data in Unrelated Samples

inferredcites →https://doi.org/10.1371/journal.pmed.1001779openalex-snapshot

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

inferredcites →https://doi.org/10.1371/journal.pone.0032316openalex-snapshot

White Matter Development in Early Puberty: A Longitudinal Volumetric and Diffusion Tensor Imaging Twin Study

inferredcites →https://doi.org/10.1523/jneurosci.0862-15.2015openalex-snapshot

Coupled Changes in Brain White Matter Microstructure and Fluid Intelligence in Later Life

inferredcites →https://doi.org/10.1523/jneurosci.1553-10.2010openalex-snapshot

A General Factor of Brain White Matter Integrity Predicts Information Processing Speed in Healthy Older People

inferredcites →https://doi.org/10.3389/fnhum.2016.00211openalex-snapshot

Studying Autism Spectrum Disorder with Structural and Diffusion Magnetic Resonance Imaging: A Survey

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1038/s41588-020-00754-2openalex-snapshot

Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction

inferred← citeshttps://doi.org/10.1101/766600openalex-snapshot

Genetic “General Intelligence,” Objectively Determined and Measured

inferred← citeshttps://doi.org/10.48550/arxiv.1903.01301openalex-snapshot

On Genetic Correlation Estimation With Summary Statistics From Genome-Wide Association Studies

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