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A constraints-based theory of the primary cause of senescence: imbalance of epigenetic and non-epigenetic information in histone crosstalk
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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The Language of Histone Crosstalk
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Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns
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Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging
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Transcriptional Noise and Somatic Mutations in the Aging Pancreas
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Survival costs of reproduction in Drosophila
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Cellular replicative capacity correlates primarily with species body mass not longevity
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Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1
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The Evolution of Lifespan and Age-Dependent Cancer Risk
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Does bristlecone pine senesce?
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Telomeres shorten during ageing of human fibroblasts
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The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis
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Increased cell-to-cell variation in gene expression in ageing mouse heart
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Uniform, optimal signal processing of mapped deep-sequencing data
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Combinatorial patterns of histone acetylations and methylations in the human genome
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Mapping the interaction surface of linker histone H10 with the nucleosome of native chromatin in vivo
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An atlas of the aging lung mapped by single cell transcriptomics and deep tissue proteomics
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SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells
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DNA methylation-based biomarkers and the epigenetic clock theory of ageing
inferredcites →https://doi.org/10.1038/sj.bjc.6602297openalex-snapshot
The age distribution of cancer and a multi-stage theory of carcinogenesis
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Epigenetic gene deregulation in cancer
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Constant mortality and fertility over age in Hydra
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Intercellular competition and the inevitability of multicellular aging
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Telomere length predicts replicative capacity of human fibroblasts.
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Relationship between donor age and the replicative lifespan of human cells in culture: A reevaluation
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BEDTools: a flexible suite of utilities for comparing genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/btq351openalex-snapshot
BigWig and BigBed: enabling browsing of large distributed datasets
inferredcites →https://doi.org/10.1093/bioinformatics/bts277openalex-snapshot
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inferredcites →https://doi.org/10.1093/database/baw014openalex-snapshot
HistoneDB 2.0: a histone database with variants—an integrated resource to explore histones and their variants
inferredcites →https://doi.org/10.1093/gerona/60.11.1369openalex-snapshot
The Naked Mole-Rat: A New Long-Living Model for Human Aging Research
inferredcites →https://doi.org/10.1101/gad.1381406openalex-snapshot
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Multivariate information transmission
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PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE
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Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
inferredcites →https://doi.org/10.1126/science.1188800openalex-snapshot
Genomic Analysis of Organismal Complexity in the Multicellular Green Alga Volvox carteri
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Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units
inferredcites →https://doi.org/10.1126/science.134.3489.1501openalex-snapshot
Cause and Effect in Biology
inferredcites →https://doi.org/10.1126/science.aah4115openalex-snapshot
Aging increases cell-to-cell transcriptional variability upon immune stimulation
inferredcites →https://doi.org/10.1146/annurev-physiol-030212-183712openalex-snapshot
Genetics of Longevity in Model Organisms: Debates and Paradigm Shifts
inferredcites →https://doi.org/10.1147/rd.41.0066openalex-snapshot
Information Theoretical Analysis of Multivariate Correlation
inferredcites →https://doi.org/10.1159/000215589openalex-snapshot
Update on Slow Aging and Negligible Senescence – A Mini-Review
inferredcites →https://doi.org/10.1162/089976603321780272openalex-snapshot
Estimation of Entropy and Mutual Information
inferredcites →https://doi.org/10.1177/0300985812471543openalex-snapshot
Spontaneous Histologic Lesions of the Adult Naked Mole Rat ( Heterocephalus glaber )
inferredcites →https://doi.org/10.1186/1756-8935-5-7openalex-snapshot
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Patterns of Cancer Incidence, Mortality, and Prevalence Across Five Continents: Defining Priorities to Reduce Cancer Disparities in Different Geographic Regions of the World
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On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other
inferredcites →https://doi.org/10.1214/aos/1013699998openalex-snapshot
The control of the false discovery rate in multiple testing under dependency
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Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast
inferredcites →https://doi.org/10.1515/hsz-2018-0449openalex-snapshot
Ageing and sources of transcriptional heterogeneity
inferredcites →https://doi.org/10.2174/1574888x12666170817141921openalex-snapshot
Histone Modifications in Aging: The Underlying Mechanisms and Implications
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Reversing the Life Cycle: Medusae Transforming into Polyps and Cell Transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa)
inferredcites →https://doi.org/10.2307/2406060openalex-snapshot
Pleiotropy, Natural Selection, and the Evolution of Senescence
inferredcites →https://doi.org/10.2741/4259openalex-snapshot
The transition from constraint to regulation at the origin of life
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Synergy and Redundancy in Dual Decompositions of Mutual Information Gain and Information Loss
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Interaction of Intestinal Bacteria with Human Rotavirus during Infection in Children
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The Logic of Scientific Discovery
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Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age
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A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1101/2021.09.22.461400openalex-snapshot
How the naked mole-rat resists senescence: a constraints-based theory
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