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Reversing the Life Cycle: Medusae Transforming into Polyps and Cell Transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa)

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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On some phenomena of coalescence and regeneration in sponges
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An electron microscopic study of early developmental stages, myogenesis, oogenesis and cnidogenesis in the anthomedusa, Podocoryne carnea M. Sars
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Untersuchungen �ber Dedifferenzierungsvorg�nge bei Medusenknospen und Medusen vonPodocoryne carnea M. Sars
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Die Entwicklungsleistungen der Medusenknospen und Medusen vonPodocoryne carnea M. Sars nach Isolation und Dissoziation
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Transdifferentiation and regeneration in vitro
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Cell cycles and in vitro transdifferentiation and regeneration of isolated, striated muscle of jellyfish
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The jellyfish and its polyp: a comparative study of gene expression monitored by the protein patterns, using two-dimensional gels with double-label autoradiography
inferredcites →https://doi.org/10.1016/0092-8674(84)90275-7openalex-snapshot
Isolated, mononucleated, striated muscle can undergo pluripotent transdifferentiation and form a complex regenerate
inferredcites →https://doi.org/10.1016/0092-8674(89)90935-5openalex-snapshot
MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer
inferredcites →https://doi.org/10.1016/0166-2236(80)90006-5openalex-snapshot
Jellyfish neurobiology since Romanes
inferredcites →https://doi.org/10.1016/0168-9525(92)90135-qopenalex-snapshot
Continuous conversion of neuron phenotype in hydra
inferredcites →https://doi.org/10.1016/0922-3371(88)90109-8openalex-snapshot
Genomic multipotentiality of differentiated somatic cells
inferredcites →https://doi.org/10.1016/b978-0-12-368104-1.50006-7openalex-snapshot
Aging and Regression in the Colonial Marine Hydroid Campanularia flexuosa with Special Reference to Senescence in Hydroids
inferredcites →https://doi.org/10.1016/s0074-7696(08)62077-xopenalex-snapshot
Transdifferentiation in Medusae
inferredcites →https://doi.org/10.1086/397707openalex-snapshot
Development and Medusa-Bud Formation in the Hydromedusae
inferredcites →https://doi.org/10.1086/physzool.26.4.30152158openalex-snapshot
The Regression-Replacement Cycle of Hydranths of Obelia and Campanularia
inferredcites →https://doi.org/10.1093/geronj/18.1.23openalex-snapshot
Studies on the Comparative Physiology of Aging. IV. Age and Mortality of Some Marine Cnidaria in the Laboratory
inferredcites →https://doi.org/10.1093/icb/22.4.753openalex-snapshot
Asexual Development of Ascidians: Its Biological Significance, Diversity, and Morphogenesis
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Zoogeography and life cycle patterns of Mediterranean hydromedusae (Cnidaria)
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Life stage specific expression of a myosin heavy chain in the hydrozoan Podocoryne carnea
inferredcites →https://doi.org/10.1111/j.1469-185x.1953.tb01381.xopenalex-snapshot
LA PÉRENNITÉ SOMATIQUE
inferredcites →https://doi.org/10.1126/science.3175662openalex-snapshot
MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts
inferredcites →https://doi.org/10.1126/science.6719127openalex-snapshot
Activation of Dormant Genes in Specialized Cells
inferredcites →https://doi.org/10.1242/jcs.29.1.17openalex-snapshot
Development of hydra lacking nerve and interstitial cells
inferredcites →https://doi.org/10.1515/9781400858712openalex-snapshot
The Evolution of Individuality
inferredcites →https://doi.org/10.1515/znb-1956-0708openalex-snapshot
Experimentelle Untersuchungen über die Entstehung asexueller Klone bei der Hydromeduse Eleutheria dichotoma
inferredcites →https://doi.org/10.2307/5403openalex-snapshot
The Evolution of Life-histories
inferredcites →https://doi.org/10.3354/meps022181openalex-snapshot
Reversible metamorphosis in coral planula larvae
inferredcites →https://doi.org/10.5962/bhl.title.6435openalex-snapshot
The biology of senescence

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Faunistic survey of Hydromedusae (Cnidaria, Medusozoa) from the coast of Paraná State, Southern Brazil
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The non-Siphonophoran Hydrozoa (Cnidaria) of Salento, Italy with notes on their life-cycles: an illustrated guide
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Benthic hydroids (Cnidaria, Hydrozoa) from bathyal and abyssal depths of the Northeast Atlantic held in the modern Discovery Collections
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Regenerative Capacity of the Upside-down Jellyfish Cassiopea xamachana.
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Cell-substrate interactions in Cnidaria
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Whole‐Ocean Changes in Silica and Ge/Si Ratios During the Last Deglacial Deduced From Long‐Lived Giant Glass Sponges
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Control of asymmetric cell divisions: will cnidarians provide an answer?
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Transdifferentiation in developmental biology, disease, and in therapy
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Multiple reproduction forms in the polyps of the cannonball jellyfishStomolophussp. 2: Probable life‐cycle reversal
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Cnidarian Origins of the Myxozoa
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Zoogeography of Hydrozoa: Past, Present and a Look to the Future
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Harbours as marine habitats: hydroid assemblages on sea-walls compared with natural habitats
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The effect of stress on rates of asexual reproduction in an invasive planarian
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Phylogenetics and species delimitation of two hydrozoa (phylum Cnidaria): Turritopsis (McCrady, 1857) and Pennaria (Goldfuss, 1820)
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Variability on microevolutionary and macroevolutionary scales: a review on patterns of morphological variation in Cnidaria Medusozoa
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Ecological Models for Gene Therapy. I. Models for Intraorganismal Ecology
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Muscle Wasting, Dysfunction, and Inflammaging
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Marine resources and animals in modern biotechnology
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Aging and longevity in the simplest animals and the quest for immortality
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Aging's competing paradigms: Another decade of investigation into damage-driven versus programmed theories
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Aging and group selection: New arguments in favor of partially directed evolution
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Telomerase activity is not related to life history stage in the jellyfish Cassiopea sp.
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Rethinking Differentiation: Stem Cells, Regeneration, and Plasticity
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Hydrozoan insights in animal development and evolution
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A polyp from nothing: The extreme regeneration capacity of the Atlantic invasive sun corals Tubastraea coccinea and T. tagusensis (Anthozoa, Scleractinia)
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The bijection from data to parameter space with the standard DEB model quantifies the supply–demand spectrum
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More constraint on ParaHox than Hox gene families in early metazoan evolution
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A mapping of an ensemble of mitochondrial sequences for various organisms into 3D space based on the word composition
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Complete mitochondrial genome and evolutionary analysis of Turritopsis dohrnii, the “immortal” jellyfish with a reversible life-cycle
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Morphological and ultrastructural analysis of Turritopsis nutricula during life cycle reversal
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Aging is a deprivation syndrome driven by a germ–soma conflict
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The Biology of Reproduction
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Preface
inferred← citeshttps://doi.org/10.1017/9781108758970.002openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1017/9781108758970.003openalex-snapshot
Introductory Concepts
inferred← citeshttps://doi.org/10.1017/9781108758970.004openalex-snapshot
Reproduction and Life Cycle
inferred← citeshttps://doi.org/10.1017/9781108758970.005openalex-snapshot
The Natural History of Reproduction
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Parental Investment in Sexual Reproduction
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Genetics and Cytogenetics of Reproduction
inferred← citeshttps://doi.org/10.1017/9781108758970.008openalex-snapshot
Determination of Sex and Mating Type
inferred← citeshttps://doi.org/10.1017/9781108758970.009openalex-snapshot
Reproduction: a Taxonomic Survey
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Coda
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A Classification of Living Organisms
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References
inferred← citeshttps://doi.org/10.1017/9781108758970.013openalex-snapshot
Taxonomic Index
inferred← citeshttps://doi.org/10.1017/9781108758970.014openalex-snapshot
Subject Index
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Medusae morphogenesis by tissue regeneration: a case study on Cassiopea xamachana Bigelow, 1892 (Scyphozoa: Rhizostomeae)
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Avoidance of rejuvenation: a stress test for evolutionary theories of aging
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“Indirect development” increases reproductive plasticity and contributes to the success of scyphozoan jellyfish in the oceans
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The invertebrates
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Paedomorphic adaptations in a new Heterostigma species: a novel strategy for ascidians to live in soft-bottom habitats
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Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation
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Reverse development in the ctenophore Mnemiopsis leidyi
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Regeneration and clonality in Metazoa. The price to pay for evolving complexity
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Assessment of the asexual reproductive strategies of the invasive clinging jellyfish, Gonionemus vertens
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Factors affecting the spatial and temporal distribution of biofouling communities on Atlantic salmon ( Salmo salar ) farms: insights from the Broughton Archipelago, British Columbia, Canada
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The role of Cnidaria in evolution and ecology
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Life cycle, morphology and medusa ontogenesis of Turritopsis dohrnii (Cnidaria: Hydrozoa)
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The final checkpoint. Cancer as an adaptive evolutionary mechanism
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Effects of global warming on reproduction and potential dispersal of Mediterranean Cnidarians
inferred← citeshttps://doi.org/10.1086/697071openalex-snapshot
Regeneration of the Rhopalium and the Rhopalial Nervous System in the Box Jellyfish Tripedalia cystophora
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How Life History Shapes Optimal Patterns of Senescence: Implications from Individuals to Societies
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Tissue Cryopreservation and Cryobanking: Establishment of a Cryogenic Resource for Coral Reefs
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Genome assembly and transcriptomic analyses of the repeatedly rejuvenating jellyfish Turritopsis dohrnii
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Cellular Reprogramming and Immortality: Expression Profiling Reveals Putative Genes Involved in Turritopsis dohrnii’s Life Cycle Reversal
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Regeneration and Musculature in Halved Cassiopea xamachana Ephyrae
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Germ Cell Research: A Personal Perspective
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Uncovering the mechanisms of Caenorhabditis elegans ageing from global quantification of the underlying landscape
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Cellular plasticity, caspases and autophagy; that which does not kill us, well, makes us different
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Senescence, trait parameterization and (st)age-specific forces of selection
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Developmental plasticity and the evolution of animal complex life cycles
inferred← citeshttps://doi.org/10.1101/2022.06.21.496857openalex-snapshot
New Hydra genomes reveal conserved principles of hydrozoan transcriptional regulation
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Highly regenerative species-specific genes improve age-associated features in the adult Drosophila midgut
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Nanos2+ cells give rise to germline and somatic lineages in the sea anemone Nematostella vectensis
inferred← citeshttps://doi.org/10.1101/215202openalex-snapshot
Protection from epidemics is a driving force for evolution of lifespan setpoints
inferred← citeshttps://doi.org/10.1101/310300openalex-snapshot
A constraints-based theory of the primary cause of senescence: imbalance of epigenetic and non-epigenetic information in histone crosstalk
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Biological Restraints on Indefinite Survival
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A chromosome-scale epigenetic map of the Hydra genome reveals conserved regulators of cell state
inferred← citeshttps://doi.org/10.1103/revmodphys.91.045004openalex-snapshot
Nonequilibrium physics in biology
inferred← citeshttps://doi.org/10.1111/brv.12801openalex-snapshot
A pan‐metazoan concept for adult stem cells: the wobbling Penrose landscape
inferred← citeshttps://doi.org/10.1111/brv.12959openalex-snapshot
Programmed ageing: decline of stem cell renewal, immunosenescence, and Alzheimer's disease
inferred← citeshttps://doi.org/10.1111/gtc.13165openalex-snapshot
Evolution of the Cdk4/6–Cdkn2 system in invertebrates
inferred← citeshttps://doi.org/10.1111/j.1439-0469.2006.00379.xopenalex-snapshot
Species in the genus Turritopsis (Cnidaria, Hydrozoa): a molecular evaluation
inferred← citeshttps://doi.org/10.1111/j.1600-0838.2009.01018.xopenalex-snapshot
The role of systemic inflammation in age‐related muscle weakness and wasting
inferred← citeshttps://doi.org/10.1111/jcmm.12074openalex-snapshot
Management of multicellular senescence and oxidative stress
inferred← citeshttps://doi.org/10.1111/maec.12035openalex-snapshot
Shallow‐water benthic hydroids from the M altese I slands ( C entral M editerranean)
inferred← citeshttps://doi.org/10.1126/sciadv.ado0424openalex-snapshot
Nanos2 marks precursors of somatic lineages and is required for germline formation in the sea anemone Nematostella vectensis
inferred← citeshttps://doi.org/10.1126/science.aay7319openalex-snapshot
To help aging populations, classify organismal senescence
inferred← citeshttps://doi.org/10.1126/scirobotics.aax5425openalex-snapshot
Ultragentle manipulation of delicate structures using a soft robotic gripper
inferred← citeshttps://doi.org/10.1134/s0006297913090113openalex-snapshot
How does the body know how old it is? Introducing the epigenetic clock hypothesis
inferred← citeshttps://doi.org/10.1134/s000629791712001xopenalex-snapshot
Programmed aging of mammals: Proof of concept and prospects of biochemical approaches for anti-aging therapy
inferred← citeshttps://doi.org/10.1134/s0006297922030075openalex-snapshot
Studying of Molecular Regulation of Developmental Processes of Lower Metazoans Exemplified by Cnidaria Using High-Throughput Sequencing
inferred← citeshttps://doi.org/10.1134/s0006297922120021openalex-snapshot
Is Aging an Inevitable Characteristic of Organic Life or an Evolutionary Adaptation?
inferred← citeshttps://doi.org/10.1134/s2079057012010109openalex-snapshot
Distribution of various aging patterns in the system of the animal world
inferred← citeshttps://doi.org/10.1139/cjz-2017-0261openalex-snapshot
Rudiment resorption as a response to starvation during larval development in the sea urchin Strongylocentrotus droebachiensis
inferred← citeshttps://doi.org/10.1139/z02-133openalex-snapshot
Reproduction of Cnidaria
inferred← citeshttps://doi.org/10.1139/z04-174openalex-snapshot
Reverse development in Cnidaria
inferred← citeshttps://doi.org/10.1152/physrev.00020.2018openalex-snapshot
Cellular Senescence: Aging, Cancer, and Injury
inferred← citeshttps://doi.org/10.1152/physrev.00040.2015openalex-snapshot
Neoteny, Prolongation of Youth: From Naked Mole Rats to “Naked Apes” (Humans)
inferred← citeshttps://doi.org/10.1152/physrev.00061.2017openalex-snapshot
Sarcopenia: Aging-Related Loss of Muscle Mass and Function
inferred← citeshttps://doi.org/10.11646/zootaxa.2590.1.1openalex-snapshot
Some anthoathecate hydroids and limnopolyps (Cnidaria, Hydrozoa) from the Hawaiian archipelago
inferred← citeshttps://doi.org/10.1186/s12915-024-01956-4openalex-snapshot
Highly regenerative species-specific genes improve age-associated features in the adult Drosophila midgut
inferred← citeshttps://doi.org/10.1186/s13059-023-02888-yopenalex-snapshot
Ageing as a software design flaw
inferred← citeshttps://doi.org/10.1186/s13104-025-07378-xopenalex-snapshot
Cool temperature inhibits binary fission and results in phenotypic and transcriptomic changes that suggest inducible aging in Diadumene lineata
inferred← citeshttps://doi.org/10.1201/9781315371214-3openalex-snapshot
The Diverse Demography of Aging
inferred← citeshttps://doi.org/10.1285/i15910725v29p107openalex-snapshot
Unique behaviours of the hydroids of Eugymnanthea (Hydrozoa,Leptomedusae,Eirenidae) living in the mantle cavity of bivalves
inferred← citeshttps://doi.org/10.13140/rg.2.1.1825.4881openalex-snapshot
Senescence Ecology: Aging in a Population of Wild Brown Mouse Lemurs (Microcebus rufus)
inferred← citeshttps://doi.org/10.1371/journal.pone.0145314openalex-snapshot
Life Cycle Reversal in Aurelia sp.1 (Cnidaria, Scyphozoa)
inferred← citeshttps://doi.org/10.1387/ijdb.062152jsopenalex-snapshot
Induction of reverse development in two marine Hydrozoans
inferred← citeshttps://doi.org/10.1387/ijdb.11902686openalex-snapshot
Cnidarians as a model system for understanding evolution and regeneration
inferred← citeshttps://doi.org/10.1534/g3.119.400487openalex-snapshot
Transcriptome Characterization of Reverse Development in Turritopsis dohrnii (Hydrozoa, Cnidaria)
inferred← citeshttps://doi.org/10.1684/ejd.2019.3534openalex-snapshot
Ecobiological approach to research regarding ageing and diseases
inferred← citeshttps://doi.org/10.17863/cam.76473openalex-snapshot
Natural Selection Reconsidered
inferred← citeshttps://doi.org/10.18632/aging.102981openalex-snapshot
Perspectives of Homo sapiens lifespan extension: focus on external or internal resources?
inferred← citeshttps://doi.org/10.2108/zs150186openalex-snapshot
De Novo Assembly of the Transcriptome of Turritopsis, a Jellyfish that Repeatedly Rejuvenates
inferred← citeshttps://doi.org/10.2217/rme-2019-0062openalex-snapshot
Toward a Unified Theory of Aging and Regeneration
inferred← citeshttps://doi.org/10.22215/etd/2022-15294openalex-snapshot
Equilibrium Conditions in the Evolution of Senescence
inferred← citeshttps://doi.org/10.2331/suisan.71.979openalex-snapshot
II. Ecology of jellyfishes
inferred← citeshttps://doi.org/10.23868/201812041openalex-snapshot
Directed myogenic reprogramming of differentiated cells
inferred← citeshttps://doi.org/10.2478/sh-2018-0001openalex-snapshot
Dynamic Essences: Absolute, Prospective, Retrospective, and Relative Modalities
inferred← citeshttps://doi.org/10.31857/s0320972522020075openalex-snapshot
Исследования молекулярной регуляции процессов развития низших многоклеточных на примере стрекающих с использованием технологий высокопроизводительного секвенирования
inferred← citeshttps://doi.org/10.3389/fcell.2022.1024489openalex-snapshot
Cell polarity signalling at the birth of multicellularity: What can we learn from the first animals
inferred← citeshttps://doi.org/10.3389/fcell.2026.1893030openalex-snapshot
Telomerase expression and activity in the immortal cnidarian Hydra
inferred← citeshttps://doi.org/10.3389/fmolb.2021.660959openalex-snapshot
Alternative Animal Models of Aging Research
inferred← citeshttps://doi.org/10.3390/d16100629openalex-snapshot
The Portofino Promontory: 200 Years of History of Marine Biology
inferred← citeshttps://doi.org/10.3390/d17100694openalex-snapshot
Medusae (Cnidaria) of Reunion Island (South West Indian Ocean): Diversity, Abundance and Distribution
inferred← citeshttps://doi.org/10.3390/fluids4030169openalex-snapshot
Naut Your Everyday Jellyfish Model: Exploring How Tentacles and Oral Arms Impact Locomotion
inferred← citeshttps://doi.org/10.3390/genes12050758openalex-snapshot
Regeneration Potential of Jellyfish: Cellular Mechanisms and Molecular Insights
inferred← citeshttps://doi.org/10.3410/f.736760786.793566294openalex-snapshot
Faculty Opinions recommendation of Transcriptome Characterization of Reverse Development in Turritopsis dohrnii (Hydrozoa, Cnidaria).
inferred← citeshttps://doi.org/10.3917/top.154.0041openalex-snapshot
L’Incontournable vieillissement
inferred← citeshttps://doi.org/10.3989/scimar.2004.68s25openalex-snapshot
Fauna of the Mediterranean Hydrozoa.
inferred← citeshttps://doi.org/10.4000/socio-anthropologie.8519openalex-snapshot
Méduse et médicament, les belles ambivalences
inferred← citeshttps://doi.org/10.4236/jmp.2022.132015openalex-snapshot
The Concept of Time: A Grand Unified Reaction Platform
inferred← citeshttps://doi.org/10.5281/zenodo.44428openalex-snapshot
Estimation Of Spatially-Correlated Random Fields With Compressed Observations
inferred← citeshttps://doi.org/10.5406/visuartsrese.40.1.0087openalex-snapshot
Jellyfish and Transformative Pedagogy
inferred← citeshttps://doi.org/10.5860/choice.48-1510openalex-snapshot
Rationality and the genetic challenge: making people better?
inferred← citeshttps://doi.org/10.5962/bhl.part.80242openalex-snapshot
Revision of the European athecate hydroids and their medusae (Hydrozoa, Cnidaria): Families Oceanidae and Pachycordylidae
inferred← citeshttps://doi.org/10.5962/bhl.part.80395openalex-snapshot
The European athecate hydroids and their medusae (Hydrozoa, Cnidaria): Filifera Part 2
inferred← citeshttps://doi.org/10.6026/97320630010586openalex-snapshot
The conserved mitochondrial gene distribution in relatives of Turritopsis nutricula, an immortal jellyfish
inferred← citeshttps://doi.org/10.64076/iedc250724.01openalex-snapshot
Genes vs mind: possible consequences in the age of social media
inferred← citeshttps://doi.org/10.65393/cmof7904openalex-snapshot
TURRITOPSIS SP. ( TSP. ) COULD BE USED TO EXPLORE SYSTEM REJUVENATION, SELF-REPAIR AND REGENERATION HUMAN
inferred← citeshttps://doi.org/10.70675/696a1221z2d60z4abbz81a7z419297106e8dopenalex-snapshot
Conscience et Idéalité : la théorie phénoménologique de Husserl (de ses travaux mathématiques jusqu'aux Ideen I)
inferred← citeshttps://doi.org/10.70675/6bc5d1cdz71abz4041z846bzdf36af17baa8openalex-snapshot
Coevolution of sociality and ageing in animal societies
inferred← citeshttps://doi.org/10.70675/b08ad2dbz2d48z46bfz9352z53cff5494698openalex-snapshot
Analysis of the transcriptional basis of natural transdifferentiation initiation in Y cell using Caenorhabditis elegans as a model organism
inferred← citeshttps://doi.org/10.70675/d56c5c28ze42dz448azbf51z5629a5730738openalex-snapshot
Ces rêves qui font grandir : Le rêve initiatique chez l’enfant et l’adolescent dans le roman d’aventures féeriques au XXIe siècle
inferred← citeshttps://doi.org/10.70675/ea0d9b85zd8b9z4fedzae80z738885fb5ca4openalex-snapshot
Natural variations in yeast aging reveal genetic and environmental factors
inferred← citeshttps://doi.org/10.7554/elife.05506openalex-snapshot
Distinct mechanisms underlie oral vs aboral regeneration in the cnidarian Hydractinia echinata
inferred← citeshttps://doi.org/10.7717/peerj.4225openalex-snapshot
Ontogeny reversal and phylogenetic analysis of Turritopsis sp.5 (Cnidaria, Hydrozoa, Oceaniidae), a possible new species endemic to Xiamen, China
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