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pheno-seq – linking morphological features to gene expression in 3D cell culture systems

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EMT: 2016
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Prox1 Promotes Expansion of the Colorectal Cancer Stem Cell Population to Fuel Tumor Growth and Ischemia Resistance
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PROX1 Promotes Metabolic Adaptation and Fuels Outgrowth of Wnthigh Metastatic Colon Cancer Cells
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The Technology and Biology of Single-Cell RNA Sequencing
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In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus
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Distinct Types of Tumor-Initiating Cells Form Human Colon Cancer Tumors and Metastases
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Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity
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Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression
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Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression
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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
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Malignant MCF10CA1 Cell Lines Derived from Premalignant Human Breast Epithelial MCF10AT Cells
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Tumour heterogeneity in the clinic
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Arabidopsis PROTEASOME REGULATOR1 is required for auxin-mediated suppression of proteasome activity and regulates auxin signalling
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Bayesian approach to single-cell differential expression analysis
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Pooled CRISPR screening with single-cell transcriptome readout
inferredcites →https://doi.org/10.1038/nmeth.4437openalex-snapshot
Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations
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Expansion of patient-derived circulating tumor cells from liquid biopsies using a CTC microfluidic culture device
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Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update
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Intra-tumour diversification in colorectal cancer at the single-cell level
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Reg4 + deep crypt secretory cells function as epithelial niche for Lgr5 + stem cells in colon
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Genetic subclone architecture of tumor clone-initiating cells in colorectal cancer
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Integrating single-cell RNA-Seq with spatial transcriptomics in pancreatic ductal adenocarcinoma using multimodal intersection analysis
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inferredcites →https://doi.org/10.1179/his.2006.29.2.99openalex-snapshot
A Short History of Histopathology Technique
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Colorectal cancer‐initiating cells caught in the act
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