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Pleotropic effects of PPARD accelerate colorectal tumor progression and invasion
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1 of the 50 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1002/jcb.21852 (notice 2015-01-29).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jcb.21852openalex-snapshot
Regulation of Wnt/β‐catenin pathway by cPLA 2 α and PPARδ
inferredcites →https://doi.org/10.1002/mc.20546openalex-snapshot
Regulation of peroxisome proliferator‐activated receptor‐β/δ by the APC/β‐CATENIN pathway and nonsteroidal antiinflammatory drugs
inferredcites →https://doi.org/10.1007/s10753-013-9791-zopenalex-snapshot
The PPARβ/δ Agonist GW501516 Attenuates Peritonitis in Peritoneal Fibrosis via Inhibition of TAK1–NFκB Pathway in Rats
inferredcites →https://doi.org/10.1007/s13277-009-0012-1openalex-snapshot
Identification of key genes for carcinogenic pathways associated with colorectal adenoma-to-carcinoma progression
inferredcites →https://doi.org/10.1016/0016-5085(85)90333-6openalex-snapshot
Prognostic factors in colorectal carcinomas arising in adenomas: Implications for lesions removed by endoscopic polypectomy
inferredcites →https://doi.org/10.1016/0092-8674(90)90186-iopenalex-snapshot
A genetic model for colorectal tumorigenesis
inferredcites →https://doi.org/10.1016/j.bcp.2012.09.031openalex-snapshot
Targeting peroxisome proliferator-activated receptor-β/δ in colon cancer: How to aim?
inferredcites →https://doi.org/10.1016/j.bmc.2016.11.035openalex-snapshot
Structure-guided development of covalent TAK1 inhibitors
inferredcites →https://doi.org/10.1016/j.cell.2011.12.033openalex-snapshot
TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers
inferredcites →https://doi.org/10.1016/j.cell.2012.12.012openalex-snapshot
Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
inferredcites →https://doi.org/10.1016/j.cellsig.2007.03.008openalex-snapshot
Proinvasive activity of BMP-7 through SMAD4 /src -independent and ERK/ Rac /JNK -dependent signaling pathways in colon cancer cells☆
inferredcites →https://doi.org/10.1016/j.tem.2015.09.004openalex-snapshot
Establishing the Role of PPARβ/δ in Carcinogenesis
inferredcites →https://doi.org/10.1016/s0016-5085(03)00376-7openalex-snapshot
Genetic testing for high-risk colon cancer patients1 1Abbreviations used in this paper: FAP, familial adenomatous polyposis; HMPS, hereditary mixed polyposis syndrome; HNPCC, hereditary nonpolyposis colon cancer; JPS, juvenile polyposis; MMR, mutation mismatch repair; MSI, microsatellite…
inferredcites →https://doi.org/10.1016/s0092-8674(00)81664-5openalex-snapshot
PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs
inferredcites →https://doi.org/10.1016/s0092-8674(02)01014-0openalex-snapshot
The β-Catenin/TCF-4 Complex Imposes a Crypt Progenitor Phenotype on Colorectal Cancer Cells
inferredcites →https://doi.org/10.1021/jm00043a002openalex-snapshot
5,7-Dimethoxy-3-(4-Pyridinyl)Quinoline Is a Potent and Selective Inhibitor of Human Vascular .beta.-Type Platelet-Derived Growth Factor Receptor Tyrosine Kinase
inferredcites →https://doi.org/10.1021/jm900464jopenalex-snapshot
Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activated Receptor δ (PPARδ) Antagonist
inferredcites →https://doi.org/10.1038/nature08137openalex-snapshot
Telomerase modulates Wnt signalling by association with target gene chromatin
inferredcites →https://doi.org/10.1038/nature13572openalex-snapshot
eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies
inferredcites →https://doi.org/10.1038/nature17173openalex-snapshot
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
inferredcites →https://doi.org/10.1038/ncomms7769openalex-snapshot
CDK1 structures reveal conserved and unique features of the essential cell cycle CDK
inferredcites →https://doi.org/10.1038/ng1997openalex-snapshot
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion
inferredcites →https://doi.org/10.1038/nm.3146openalex-snapshot
PPARβ/δ governs Wnt signaling and bone turnover
inferredcites →https://doi.org/10.1038/nm1026openalex-snapshot
Peroxisome proliferator–activated receptor-δ attenuates colon carcinogenesis
inferredcites →https://doi.org/10.1038/nm993openalex-snapshot
Activation of nuclear hormone receptor peroxisome proliferator–activated receptor-δ accelerates intestinal adenoma growth
inferredcites →https://doi.org/10.1038/nrc1254openalex-snapshot
Peroxisome-proliferator-activated receptors and cancers: complex stories
inferredcites →https://doi.org/10.1038/nrm2838openalex-snapshot
The mechanism of eukaryotic translation initiation and principles of its regulation
inferredcites →https://doi.org/10.1038/sj.bjc.6603343openalex-snapshot
Expression of PPARδ in multistage carcinogenesis of the colorectum: implications of malignant cancer morphology
inferredcites →https://doi.org/10.1073/pnas.0607948103openalex-snapshot
Crosstalk between peroxisome proliferator-activated receptor δ and VEGF stimulates cancer progression
inferredcites →https://doi.org/10.1073/pnas.0908682107openalex-snapshot
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment
inferredcites →https://doi.org/10.1073/pnas.1203015109openalex-snapshot
Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity
inferredcites →https://doi.org/10.1073/pnas.1505787112openalex-snapshot
CDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation
inferredcites →https://doi.org/10.1073/pnas.171610498openalex-snapshot
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
inferredcites →https://doi.org/10.1073/pnas.97.24.13275openalex-snapshot
Prostacyclin-mediated activation of peroxisome proliferator-activated receptor δ in colorectal cancer
inferredcites →https://doi.org/10.1093/jnci/dju052openalex-snapshot
Potentiation of Colon Cancer Susceptibility in Mice by Colonic Epithelial PPAR-δ/β Overexpression
inferredcites →https://doi.org/10.1097/shk.0b013e3181cd86d6openalex-snapshot
ACTIVATION OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-β/δ ATTENUATES MYOCARDIAL ISCHEMIA/REPERFUSION INJURY IN THE RAT
inferredcites →https://doi.org/10.1101/cshperspect.a012336openalex-snapshot
Translational Control in Cancer Etiology
inferredcites →https://doi.org/10.1126/science.275.5307.1787openalex-snapshot
Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC
inferredcites →https://doi.org/10.1128/mcb.25.5.1696-1712.2005openalex-snapshot
Epithelium-Mesenchyme Interactions Control the Activity of Peroxisome Proliferator-Activated Receptor β/δ during Hair Follicle Development
inferredcites →https://doi.org/10.1158/0008-5472.can-07-2735openalex-snapshot
Mouse Model of Colonic Adenoma-Carcinoma Progression Based on Somatic Apc Inactivation
inferredcites →https://doi.org/10.1158/0008-5472.can-13-0322openalex-snapshot
PPARδ Induces Estrogen Receptor-Positive Mammary Neoplasia through an Inflammatory and Metabolic Phenotype Linked to mTOR Activation
inferredcites →https://doi.org/10.1158/0008-5472.can-14-2036openalex-snapshot
Suppressing TGFβ Signaling in Regenerating Epithelia in an Inflammatory Microenvironment Is Sufficient to Cause Invasive Intestinal Cancer
inferredcites →https://doi.org/10.1164/rccm.201002-0240ocopenalex-snapshot
Protective Role of Peroxisome Proliferator–activated Receptor-β/δ in Septic Shock
inferredcites →https://doi.org/10.1165/rcmb.2007-0426ocopenalex-snapshot
Peroxisome Proliferator–Activated Receptor β/δ Expression and Activation in Lung Cancer
inferredcites →https://doi.org/10.1172/jci.insight.91419openalex-snapshot
Metastasis regulation by PPARD expression in cancer cells
inferredcites →https://doi.org/10.1186/1747-1028-5-11openalex-snapshot
An overview of Cdk1-controlled targets and processes
inferredcites →https://doi.org/10.1371/journal.pone.0025271openalex-snapshot
GW501516, a PPARδ Agonist, Ameliorates Tubulointerstitial Inflammation in Proteinuric Kidney Disease via Inhibition of TAK1-NFκB Pathway in Mice
inferredcites →https://doi.org/10.1371/journal.pone.0063011openalex-snapshot
Regulation of TAK1/TAB1-Mediated IL-1β Signaling by Cytoplasmic PPARβ/δ
inferredcites →https://doi.org/10.18632/oncotarget.2037openalex-snapshot
GSK-3 as potential target for therapeutic intervention in cancer
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.108049openalex-snapshot
Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P
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