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Lipid associated polygenic enrichment in Alzheimer’s disease

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.2016.21042openalex-snapshot
Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease
inferredcites →https://doi.org/10.1001/jama.2017.17219openalex-snapshot
Mendelian Randomization
inferredcites →https://doi.org/10.1001/jamaneurol.2016.0150openalex-snapshot
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
inferredcites →https://doi.org/10.1001/jamaneurol.2018.0372openalex-snapshot
Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum
inferredcites →https://doi.org/10.1002/j.1460-2075.1996.tb00949.xopenalex-snapshot
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities.
inferredcites →https://doi.org/10.1007/s00401-017-1693-yopenalex-snapshot
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia
inferredcites →https://doi.org/10.1007/s11883-012-0307-3openalex-snapshot
Dyslipidemia and the Risk of Alzheimer’s Disease
inferredcites →https://doi.org/10.1016/b978-0-444-64076-5.00026-0openalex-snapshot
The genetic landscape of Alzheimer disease
inferredcites →https://doi.org/10.1016/j.biopsych.2009.02.013openalex-snapshot
Meta-Analysis of Alzheimer's Disease Risk with Obesity, Diabetes, and Related Disorders
inferredcites →https://doi.org/10.1016/j.neuron.2015.11.013openalex-snapshot
Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse
inferredcites →https://doi.org/10.1016/s0140-6736(17)31363-6openalex-snapshot
Dementia prevention, intervention, and care
inferredcites →https://doi.org/10.1016/s1474-4422(11)70072-2openalex-snapshot
The projected effect of risk factor reduction on Alzheimer's disease prevalence
inferredcites →https://doi.org/10.1016/s1474-4422(14)70136-xopenalex-snapshot
Potential for primary prevention of Alzheimer's disease: an analysis of population-based data
inferredcites →https://doi.org/10.1038/mp.2015.6openalex-snapshot
Genetic overlap between Alzheimer’s disease and Parkinson’s disease at the MAPT locus
inferredcites →https://doi.org/10.1038/nature14132openalex-snapshot
New genetic loci link adipose and insulin biology to body fat distribution
inferredcites →https://doi.org/10.1038/nature14177openalex-snapshot
Genetic studies of body mass index yield new insights for obesity biology
inferredcites →https://doi.org/10.1038/ng.2756openalex-snapshot
Systematic identification of trans eQTLs as putative drivers of known disease associations
inferredcites →https://doi.org/10.1038/ng.2797openalex-snapshot
Discovery and refinement of loci associated with lipid levels
inferredcites →https://doi.org/10.1038/ng.2802openalex-snapshot
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
inferredcites →https://doi.org/10.1038/ng.3396openalex-snapshot
A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
inferredcites →https://doi.org/10.1038/ng.3916openalex-snapshot
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
inferredcites →https://doi.org/10.1038/nn.3801openalex-snapshot
Genetic variability in the regulation of gene expression in ten regions of the human brain
inferredcites →https://doi.org/10.1038/nn.4587openalex-snapshot
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
inferredcites →https://doi.org/10.1038/nrn3012openalex-snapshot
Linking lipids to Alzheimer's disease: cholesterol and beyond
inferredcites →https://doi.org/10.1038/s41467-017-01261-5openalex-snapshot
Functional mapping and annotation of genetic associations with FUMA
inferredcites →https://doi.org/10.1038/s41586-018-0198-8openalex-snapshot
Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice
inferredcites →https://doi.org/10.1038/sdata.2016.89openalex-snapshot
Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseases
inferredcites →https://doi.org/10.1055/s-0037-1608808openalex-snapshot
Neuroimaging in Dementia
inferredcites →https://doi.org/10.1055/s-0043-103789openalex-snapshot
Apfeltyp erhöht Diabetes- und KHK-Risiko
inferredcites →https://doi.org/10.1093/aje/154.7.635openalex-snapshot
Diabetes Mellitus and Risk of Alzheimer's Disease and Dementia with Stroke in a Multiethnic Cohort
inferredcites →https://doi.org/10.1093/nar/gkq537openalex-snapshot
The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function
inferredcites →https://doi.org/10.1093/schbul/sbt168openalex-snapshot
Boosting the Power of Schizophrenia Genetics by Leveraging New Statistical Tools
inferredcites →https://doi.org/10.1126/science.1151526openalex-snapshot
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
inferredcites →https://doi.org/10.1136/bmj.j5375openalex-snapshot
Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis
inferredcites →https://doi.org/10.1161/atvbaha.116.307023openalex-snapshot
Central Nervous System Lipoproteins
inferredcites →https://doi.org/10.1161/circulationaha.115.015489openalex-snapshot
Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease
inferredcites →https://doi.org/10.1186/s12916-014-0206-2openalex-snapshot
The overlap between vascular disease and Alzheimer’s disease - lessons from pathology
inferredcites →https://doi.org/10.1371/journal.pgen.1003455openalex-snapshot
Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate
inferredcites →https://doi.org/10.1371/journal.pmed.1002258openalex-snapshot
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score
inferredcites →https://doi.org/10.1371/journal.pmed.1002272openalex-snapshot
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case–control study
inferredcites →https://doi.org/10.1371/journal.pmed.1002487openalex-snapshot
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
inferredcites →https://doi.org/10.1371/journal.pone.0148717openalex-snapshot
Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci
inferredcites →https://doi.org/10.1534/genetics.110.122549openalex-snapshot
One Hundred Years of Pleiotropy: A Retrospective
inferredcites →https://doi.org/10.2174/156720507780362119openalex-snapshot
Cholesterol Metabolism and Brain Amyloidosis: Evidence for a Role of Copper in the Clearance of A β Through the Liver
inferredcites →https://doi.org/10.2337/db16-1253openalex-snapshot
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1038/s41598-021-99760-5openalex-snapshot
Disturbance of phylogenetic layer-specific adaptation of human brain gene expression in Alzheimer's disease
inferred← citeshttps://doi.org/10.1101/2020.06.29.133702openalex-snapshot
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing
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