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Short-hairpin RNA-guided single gene knockdown reverses triple-negative breast cancer

https://doi.org/10.1101/418764
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ijc.23329openalex-snapshot
The molecular etiology of breast cancer: Evidence from biomarkers of risk
inferredcites →https://doi.org/10.1002/ijc.25207openalex-snapshot
Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms
inferredcites →https://doi.org/10.1002/ijc.27644openalex-snapshot
NOS2 enhances KRAS‐induced lung carcinogenesis, inflammation and microRNA‐21 expression
inferredcites →https://doi.org/10.1007/s12282-016-0734-zopenalex-snapshot
Gastrointestinal microbiome and breast cancer: correlations, mechanisms and potential clinical implications
inferredcites →https://doi.org/10.1016/0022-4731(86)90080-4openalex-snapshot
Carcinogenicity of catechol estrogens in Syrian hamsters
inferredcites →https://doi.org/10.1016/j.aca.2011.10.058openalex-snapshot
Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography–tandem mass spectrometry: A case study for breast cancer
inferredcites →https://doi.org/10.1016/j.cell.2011.06.006openalex-snapshot
Glioma Stem Cell Proliferation and Tumor Growth Are Promoted by Nitric Oxide Synthase-2
inferredcites →https://doi.org/10.1016/j.jsbmb.2006.06.019openalex-snapshot
Induction of A·T to G·C mutations by erroneous repair of depurinated DNA following estrogen treatment of the mammary gland of ACI rats
inferredcites →https://doi.org/10.1016/j.orcp.2016.02.007openalex-snapshot
Oestrogen exerts anti-inflammation via p38 MAPK/NF-κB cascade in adipocytes
inferredcites →https://doi.org/10.1016/s0140-6736(05)66431-8openalex-snapshot
Hormones and endometrial cancer—new data from the Million Women Study
inferredcites →https://doi.org/10.1038/bjc.1995.274openalex-snapshot
Nitric oxide synthase activity in human breast cancer
inferredcites →https://doi.org/10.1038/ncomms6987openalex-snapshot
BCL11A is a triple-negative breast cancer gene with critical functions in stem and progenitor cells
inferredcites →https://doi.org/10.1038/nrclinonc.2015.10openalex-snapshot
BCL11A—targeting triple-negative breast cancer?
inferredcites →https://doi.org/10.1038/nrclinonc.2015.9openalex-snapshot
LUX-Lung trials—not all mutations are created equal
inferredcites →https://doi.org/10.1056/nejmra012284openalex-snapshot
Breast and Ovarian Cancer
inferredcites →https://doi.org/10.1056/nejmra050776openalex-snapshot
Estrogen Carcinogenesis in Breast Cancer
inferredcites →https://doi.org/10.1073/pnas.0409854102openalex-snapshot
Rapid nitric oxide-mediated S-nitrosylation of estrogen receptor: Regulation of estrogen-dependent gene transcription
inferredcites →https://doi.org/10.1073/pnas.1422015112openalex-snapshot
Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
inferredcites →https://doi.org/10.1093/carcin/bgg004openalex-snapshot
Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer
inferredcites →https://doi.org/10.1093/cvr/cvp368openalex-snapshot
17 -Estradiol induces protein S-nitrosylation in the endothelium
inferredcites →https://doi.org/10.1093/hmg/ddu172openalex-snapshot
The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population
inferredcites →https://doi.org/10.1093/jnci/djr257openalex-snapshot
Incidence of Breast Cancer in the United States: Current and Future Trends
inferredcites →https://doi.org/10.1093/jnci/djv048openalex-snapshot
Annual Report to the Nation on the Status of Cancer, 1975-2011, Featuring Incidence of Breast Cancer Subtypes by Race/Ethnicity, Poverty, and State
inferredcites →https://doi.org/10.1093/jnci/djv159openalex-snapshot
Estrogen Receptor Status and the Future Burden of Invasive and In Situ Breast Cancers in the United States
inferredcites →https://doi.org/10.1093/jnci/djw029openalex-snapshot
The Intestinal Microbiome and Estrogen Receptor–Positive Female Breast Cancer
inferredcites →https://doi.org/10.1136/jclinpath-2012-201085openalex-snapshot
Ki67 and proliferation in breast cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-13-2611openalex-snapshot
BRCA1 Deficiency Exacerbates Estrogen-Induced DNA Damage and Genomic Instability
inferredcites →https://doi.org/10.1186/1479-5876-10-253openalex-snapshot
Fecal microbial determinants of fecal and systemic estrogens and estrogen metabolites: a cross-sectional study
inferredcites →https://doi.org/10.1186/s13058-015-0527-xopenalex-snapshot
Inhibition of iNOS as a novel effective targeted therapy against triple-negative breast cancer
inferredcites →https://doi.org/10.1210/jc.2004-1421openalex-snapshot
Expression and Functional Study of Estrogen Receptor-Related Receptors in Human Prostatic Cells and Tissues
inferredcites →https://doi.org/10.1210/jc.2014-2222openalex-snapshot
Associations of the Fecal Microbiome With Urinary Estrogens and Estrogen Metabolites in Postmenopausal Women
inferredcites →https://doi.org/10.1210/jc.2016-2749openalex-snapshot
Familial Multiplicity of Estrogen Insensitivity Associated with a Loss-of-Function ESR1 Mutation
inferredcites →https://doi.org/10.1360/052012-148openalex-snapshot
Artemisinin and Rapamycin Compromise Nitric Oxide-driven and Hypoxia-triggered Acute Articular Synovitis in Mice
inferredcites →https://doi.org/10.1371/journal.pone.0048220openalex-snapshot
High-Fat Diet Induces Periodontitis in Mice through Lipopolysaccharides (LPS) Receptor Signaling: Protective Action of Estrogens
inferredcites →https://doi.org/10.1371/journal.pone.0100759openalex-snapshot
Expression of RUNX1 Correlates with Poor Patient Prognosis in Triple Negative Breast Cancer
inferredcites →https://doi.org/10.18632/oncotarget.9746openalex-snapshot
Lactic acidosis switches cancer cells from aerobic glycolysis back to dominant oxidative phosphorylation
inferredcites →https://doi.org/10.2741/2120openalex-snapshot
Mitochondrial oxidant generation is involved in determining why females live longer than males
inferredcites →https://doi.org/10.3389/fmicb.2017.01955openalex-snapshot
Akkermansia muciniphila May Determine Chondroitin Sulfate Ameliorating or Aggravating Osteoarthritis
inferredcites →https://doi.org/10.3390/cancers7020815openalex-snapshot
Effects of Age on the Detection and Management of Breast Cancer
inferredcites →https://doi.org/10.7150/ijbs.18278openalex-snapshot
Estradiol Suppresses TLR4-triggered Apoptosis of Decidual Stromal Cells and Drives an Anti-inflammatory T H 2 Shift by Activating SGK1

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.3390/antiox11061195openalex-snapshot
The Breast Cancer Protooncogenes HER2, BRCA1 and BRCA2 and Their Regulation by the iNOS/NOS2 Axis
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