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On prs for complex polygenic trait prediction

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/gepi.21906openalex-snapshot
Explicit Modeling of Ancestry Improves Polygenic Risk Scores and BLUP Prediction
inferredcites →https://doi.org/10.1002/gepi.21966openalex-snapshot
Polygenic Epidemiology
inferredcites →https://doi.org/10.1002/gepi.22083openalex-snapshot
Multiethnic polygenic risk scores improve risk prediction in diverse populations
inferredcites →https://doi.org/10.1007/bf01441146openalex-snapshot
A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity
inferredcites →https://doi.org/10.1016/j.ajhg.2010.11.011openalex-snapshot
GCTA: A Tool for Genome-wide Complex Trait Analysis
inferredcites →https://doi.org/10.1016/j.ajhg.2011.11.029openalex-snapshot
Five Years of GWAS Discovery
inferredcites →https://doi.org/10.1016/j.ajhg.2015.09.001openalex-snapshot
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
inferredcites →https://doi.org/10.1016/j.ajhg.2016.05.013openalex-snapshot
Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data
inferredcites →https://doi.org/10.1016/j.ajhg.2017.06.005openalex-snapshot
10 Years of GWAS Discovery: Biology, Function, and Translation
inferredcites →https://doi.org/10.1016/j.biopsych.2018.04.007openalex-snapshot
Polygenic Risk Scores: What Are They Good For?
inferredcites →https://doi.org/10.1016/j.cell.2017.05.038openalex-snapshot
An Expanded View of Complex Traits: From Polygenic to Omnigenic
inferredcites →https://doi.org/10.1016/j.cell.2018.05.051openalex-snapshot
Common Disease Is More Complex Than Implied by the Core Gene Omnigenic Model
inferredcites →https://doi.org/10.1016/j.jad.2018.02.005openalex-snapshot
The use of polygenic risk scores to identify phenotypes associated with genetic risk of bipolar disorder and depression: A systematic review
inferredcites →https://doi.org/10.1016/j.neuroimage.2010.09.025openalex-snapshot
A reproducible evaluation of ANTs similarity metric performance in brain image registration
inferredcites →https://doi.org/10.1016/j.schres.2017.10.037openalex-snapshot
The use of polygenic risk scores to identify phenotypes associated with genetic risk of schizophrenia: Systematic review
inferredcites →https://doi.org/10.1017/s0080456800012163openalex-snapshot
XV.—The Correlation between Relatives on the Supposition of Mendelian Inheritance.
inferredcites →https://doi.org/10.1038/mp.2015.12openalex-snapshot
Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population
inferredcites →https://doi.org/10.1038/nature08185openalex-snapshot
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
inferredcites →https://doi.org/10.1038/nature08494openalex-snapshot
Finding the missing heritability of complex diseases
inferredcites →https://doi.org/10.1038/ng.1108openalex-snapshot
Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs
inferredcites →https://doi.org/10.1038/ng.2579openalex-snapshot
Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies
inferredcites →https://doi.org/10.1038/ng.3390openalex-snapshot
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
inferredcites →https://doi.org/10.1038/ng.3949openalex-snapshot
Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis
inferredcites →https://doi.org/10.1038/ng.608openalex-snapshot
Common SNPs explain a large proportion of the heritability for human height
inferredcites →https://doi.org/10.1038/ng1847openalex-snapshot
Principal components analysis corrects for stratification in genome-wide association studies
inferredcites →https://doi.org/10.1038/nn.4040openalex-snapshot
Polygenic risk scores for schizophrenia and bipolar disorder predict creativity
inferredcites →https://doi.org/10.1038/nrg.2016.142openalex-snapshot
Dissecting the genetics of complex traits using summary association statistics
inferredcites →https://doi.org/10.1038/nrg.2016.27openalex-snapshot
Developing and evaluating polygenic risk prediction models for stratified disease prevention
inferredcites →https://doi.org/10.1038/nrg.2017.101openalex-snapshot
Genetic architecture: the shape of the genetic contribution to human traits and disease
inferredcites →https://doi.org/10.1038/nrg3457openalex-snapshot
Pitfalls of predicting complex traits from SNPs
inferredcites →https://doi.org/10.1038/s41576-018-0018-xopenalex-snapshot
The personal and clinical utility of polygenic risk scores
inferredcites →https://doi.org/10.1038/s41586-018-0579-zopenalex-snapshot
The UK Biobank resource with deep phenotyping and genomic data
inferredcites →https://doi.org/10.1038/s41588-018-0183-zopenalex-snapshot
Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
inferredcites →https://doi.org/10.1038/s41588-019-0481-0openalex-snapshot
A global overview of pleiotropy and genetic architecture in complex traits
inferredcites →https://doi.org/10.1038/s41588-019-0516-6openalex-snapshot
Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits
inferredcites →https://doi.org/10.1038/s41596-020-0353-1openalex-snapshot
Tutorial: a guide to performing polygenic risk score analyses
inferredcites →https://doi.org/10.1073/pnas.1119675109openalex-snapshot
The mystery of missing heritability: Genetic interactions create phantom heritability
inferredcites →https://doi.org/10.1073/pnas.58.1.199openalex-snapshot
A polygenic theory of schizophrenia.
inferredcites →https://doi.org/10.1080/01621459.2016.1251440openalex-snapshot
Error Variance Estimation in Ultrahigh-Dimensional Additive Models
inferredcites →https://doi.org/10.1086/519795openalex-snapshot
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
inferredcites →https://doi.org/10.1093/biomet/asy032openalex-snapshot
When is the first spurious variable selected by sequential regression procedures?
inferredcites →https://doi.org/10.1093/nar/gkw1133openalex-snapshot
The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)
inferredcites →https://doi.org/10.1101/203257openalex-snapshot
Polygenic risk scores applied to a single cohort reveal pleiotropy among hundreds of human phenotypes
inferredcites →https://doi.org/10.1111/j.1467-9868.2008.00674.xopenalex-snapshot
Sure Independence Screening for Ultrahigh Dimensional Feature Space
inferredcites →https://doi.org/10.1111/j.1467-9868.2011.01005.xopenalex-snapshot
Variance Estimation Using Refitted Cross-Validation in Ultrahigh Dimensional Regression
inferredcites →https://doi.org/10.1111/j.1541-0420.2010.01520.xopenalex-snapshot
Control of Population Stratification by Correlation-Selected Principal Components
inferredcites →https://doi.org/10.1111/j.2517-6161.1996.tb02080.xopenalex-snapshot
Regression Shrinkage and Selection Via the Lasso
inferredcites →https://doi.org/10.1146/annurev-clinpsy-050817-084847openalex-snapshot
Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences
inferredcites →https://doi.org/10.1159/000150748openalex-snapshot
THE GENETICAL BACKGROUND OF COMMON DISEASES
inferredcites →https://doi.org/10.1214/11-aos879openalex-snapshot
Limiting laws of coherence of random matrices with applications to testing covariance structure and construction of compressed sensing matrices
inferredcites →https://doi.org/10.1214/17-aos1575openalex-snapshot
Are discoveries spurious? Distributions of maximum spurious correlations and their applications
inferredcites →https://doi.org/10.1371/journal.pgen.1003348openalex-snapshot
Power and Predictive Accuracy of Polygenic Risk Scores
inferredcites →https://doi.org/10.1371/journal.pgen.1006711openalex-snapshot
Phenome-wide heritability analysis of the UK Biobank
inferredcites →https://doi.org/10.1371/journal.pmed.1001779openalex-snapshot
UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
inferredcites →https://doi.org/10.1371/journal.pone.0003395openalex-snapshot
Accuracy of Predicting the Genetic Risk of Disease Using a Genome-Wide Approach
inferredcites →https://doi.org/10.2307/1267351openalex-snapshot
Ridge Regression: Biased Estimation for Nonorthogonal Problems
inferredcites →https://doi.org/10.2307/1271436openalex-snapshot
Ridge Regression: Biased Estimation for Nonorthogonal Problems
inferredcites →https://doi.org/10.48550/arxiv.1306.0256openalex-snapshot
Distributions of Angles in Random Packing on Spheres
inferredcites →https://doi.org/10.48550/arxiv.1407.4443openalex-snapshot
On the Complexity of Best Arm Identification in Multi-Armed Bandit Models
inferredcites →https://doi.org/10.48550/arxiv.1512.01617openalex-snapshot
Guarding against Spurious Discoveries in High Dimensions

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.7554/elife.49962openalex-snapshot
Can education be personalised using pupils’ genetic data?
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