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Natural avirulent Shigella boydii strain in the Brazilian Amazon lacks major virulence genes and present Type II, Type III and Type VI Secretion Systems

https://doi.org/10.1101/459701
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Outgoing claims: the papers this work cites, builds on, or argues with.

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An adhesive factor found in strains ofEscherichia coli belonging to the traditional infantile enteropathogenic serotypes
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PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment
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Shigella sonnei Encodes a Functional T6SS Used for Interbacterial Competition and Niche Occupancy
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Deadly syringes: type VI secretion system activities in pathogenicity and interbacterial competition
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Single amino acid substitutions on the needle tip protein IpaD increased Shigella virulence
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Shigellosis murine model established by intraperitoneal and intranasal route of administration: a comparative comprehension overview
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The roles of the virulence factor IpaB in Shigella spp. in the escape from immune cells and invasion of epithelial cells
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Novel strain of Shigella dysenteriae serotype 7 from India
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Type II secretion: a protein secretion system for all seasons
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The role of bacterial and non-bacterial toxins in the induction of changes in membrane transport: implications for diarrhea
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Analysis and genetic manipulation of Shigella virulence determinants for vaccine development
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Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspFU
inferredcites →https://doi.org/10.1038/nature10894openalex-snapshot
The Shigella flexneri effector OspI deamidates UBC13 to dampen the inflammatory response
inferredcites →https://doi.org/10.1038/nrgastro.2013.12openalex-snapshot
Progress and pitfalls in Shigella vaccine research
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Shigella’ s ways of manipulating the host intestinal innate and adaptive immune system: a tool box for survival?
inferredcites →https://doi.org/10.1074/jbc.c200651200openalex-snapshot
Nod2 Is a General Sensor of Peptidoglycan through Muramyl Dipeptide (MDP) Detection
inferredcites →https://doi.org/10.1074/jbc.m307994200openalex-snapshot
Trihydrophobin 1 Is a New Negative Regulator of A-Raf Kinase
inferredcites →https://doi.org/10.1074/jbc.m607945200openalex-snapshot
Self-chaperoning of the Type III Secretion System Needle Tip Proteins IpaD and BipD
inferredcites →https://doi.org/10.1084/jem.20071698openalex-snapshot
Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression
inferredcites →https://doi.org/10.1086/424680openalex-snapshot
Deletion in theShigellaEnterotoxin Genes Further AttenuatesShigella flexneri2a Bearing Guanine Auxotrophy in a Phase 1 Trial of CVD 1204 and CVD 1208
inferredcites →https://doi.org/10.1089/cmb.2013.0084openalex-snapshot
Assembling Single-Cell Genomes and Mini-Metagenomes From Chimeric MDA Products
inferredcites →https://doi.org/10.1093/bioinformatics/btn227openalex-snapshot
qpcR: an R package for sigmoidal model selection in quantitative real-time polymerase chain reaction analysis
inferredcites →https://doi.org/10.1093/bioinformatics/btq210openalex-snapshot
Discovering transcriptional modules by Bayesian data integration
inferredcites →https://doi.org/10.1093/bioinformatics/btt086openalex-snapshot
QUAST: quality assessment tool for genome assemblies
inferredcites →https://doi.org/10.1093/clinids/5.supplement_4.s702openalex-snapshot
Invasive Enteric Pathogens
inferredcites →https://doi.org/10.1093/femspd/ftw027openalex-snapshot
Genome diversity of Shigella boydii
inferredcites →https://doi.org/10.1093/infdis/126.5.523openalex-snapshot
Shigellosis Due to Shigella dysenteriae 1: Relative Importance of Mucosal Invasion versus Toxin Production in Pathogenesis
inferredcites →https://doi.org/10.1093/infdis/171.2.376openalex-snapshot
Cytokine Secretion in Acute Shigellosis Is Correlated to Disease Activity and Directed More to Stool than to Plasma
inferredcites →https://doi.org/10.1093/infdis/172.5.1408openalex-snapshot
Prevalence of Shigella Enterotoxin 1 among Shigella Clinical Isolates of Diverse Serotypes
inferredcites →https://doi.org/10.1093/nar/gki954openalex-snapshot
Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery
inferredcites →https://doi.org/10.1093/nar/gkt1226openalex-snapshot
The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST)
inferredcites →https://doi.org/10.1099/jmm.0.46095-0openalex-snapshot
Identification and characterization of Shigella boydii 20 serovar nov., a new and emerging Shigella serotype
inferredcites →https://doi.org/10.1111/j.1349-7006.2010.01656.xopenalex-snapshot
Negative role of trihydrophobin 1 in breast cancer growth and migration
inferredcites →https://doi.org/10.1111/j.1469-0691.2004.00897.xopenalex-snapshot
Prevalence of the sat, set and sen genes among diverse serotypes of Shigella flexneri strains isolated from patients with acute diarrhoea
inferredcites →https://doi.org/10.1111/j.1472-765x.1989.tb00262.xopenalex-snapshot
Rapid extraction of bacterial genomic DNA with guanidium thiocyanate
inferredcites →https://doi.org/10.1111/mmi.12124openalex-snapshot
S higella IpaD has a dual role: signal transduction from the type III secretion system needle tip and intracellular secretion regulation
inferredcites →https://doi.org/10.1126/science.1084677openalex-snapshot
Nod1 Detects a Unique Muropeptide from Gram-Negative Bacterial Peptidoglycan
inferredcites →https://doi.org/10.1128/cmr.00031-16openalex-snapshot
Survival of the Fittest: How Bacterial Pathogens Utilize Bile To Enhance Infection
inferredcites →https://doi.org/10.1128/cmr.00032-07openalex-snapshot
Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion
inferredcites →https://doi.org/10.1128/cvi.00608-15openalex-snapshot
Evaluation of the Safety, Tolerability, and Immunogenicity of an Oral, Inactivated Whole-Cell Shigella flexneri 2a Vaccine in Healthy Adult Subjects
inferredcites →https://doi.org/10.1128/cvi.00661-14openalex-snapshot
Shigella Outer Membrane Protein PSSP-1 Is Broadly Protective against Shigella Infection
inferredcites →https://doi.org/10.1128/iai.00975-13openalex-snapshot
Analysis of the Proteome of Intracellular Shigella flexneri Reveals Pathways Important for Intracellular Growth
inferredcites →https://doi.org/10.1128/iai.01483-15openalex-snapshot
Macrophage Apoptosis Triggered by IpaD from Shigella flexneri
inferredcites →https://doi.org/10.1128/iai.63.5.1947-1954.1995openalex-snapshot
Antibody and cytokine responses in a mouse pulmonary model of Shigella flexneri serotype 2a infection
inferredcites →https://doi.org/10.1128/iai.65.12.5338-5341.1997openalex-snapshot
A systemic downregulation of gamma interferon production is associated with acute shigellosis
inferredcites →https://doi.org/10.1128/iai.67.7.3437-3443.1999openalex-snapshot
Vaccination against Shigellosis with Attenuated Shigella flexneri 2a Strain SC602
inferredcites →https://doi.org/10.1128/iai.68.3.1034-1039.2000openalex-snapshot
Shigella flexneri 2a Strain CVD 1207, with Specific Deletions in virG , sen , set , and guaBA , Is Highly Attenuated in Humans
inferredcites →https://doi.org/10.1128/iai.71.12.7002-7013.2003openalex-snapshot
Analysis of Virulence and Inflammatory Potential of Shigella flexneri Purine Biosynthesis Mutants
inferredcites →https://doi.org/10.1128/jcm.37.11.3608-3611.1999openalex-snapshot
Prevalence of Shigella Enterotoxins 1 and 2 among Shigella Strains Isolated from Patients with Traveler's Diarrhea
inferredcites →https://doi.org/10.1128/jcm.41.1.110-117.2003openalex-snapshot
Phenotypic and Genotypic Characterization of Provisional Serotype Shigella flexneri 1c and Clonal Relationships with 1a and 1b Strains Isolated in Bangladesh
inferredcites →https://doi.org/10.1136/gut.40.4.505openalex-snapshot
Effect of shigella enterotoxin 1 (ShET1) on rabbit intestine in vitro and in vivo.
inferredcites →https://doi.org/10.1142/s0219720012310038openalex-snapshot
VOLCANO PLOTS IN ANALYZING DIFFERENTIAL EXPRESSIONS WITH mRNA MICROARRAYS
inferredcites →https://doi.org/10.1155/2013/412370openalex-snapshot
A Pentaplex PCR Assay for the Detection and Differentiation ofShigellaSpecies
inferredcites →https://doi.org/10.1155/2014/539697openalex-snapshot
Virulence Factors Associated with Pediatric Shigellosis in Brazilian Amazon
inferredcites →https://doi.org/10.1172/jci117991openalex-snapshot
Shigella enterotoxin 1: an enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro.
inferredcites →https://doi.org/10.1186/1471-2334-5-8openalex-snapshot
Detection of virulence genes in Malaysian Shigellaspecies by multiplex PCR assay
inferredcites →https://doi.org/10.1186/s12879-015-1035-4openalex-snapshot
Divergent cerebrospinal fluid cytokine network induced by non-viral and different viral infections on the central nervous system
inferredcites →https://doi.org/10.1371/journal.pone.0002955openalex-snapshot
Identification and Functional Characterization of Gene Components of Type VI Secretion System in Bacterial Genomes
inferredcites →https://doi.org/10.1371/journal.pone.0029920openalex-snapshot
Trihydrophobin 1 Phosphorylation by c-Src Regulates MAPK/ERK Signaling and Cell Migration
inferredcites →https://doi.org/10.1371/journal.pone.0035495openalex-snapshot
Perceptions and Experiences of Research Participants on Gender-Based Violence Community Based Survey: Implications for Ethical Guidelines
inferredcites →https://doi.org/10.1371/journal.pone.0036446openalex-snapshot
Quantitative RT-PCR profiling of the Rabbit Immune Response: Assessment of Acute Shigella flexneri Infection
inferredcites →https://doi.org/10.1371/journal.pone.0064748openalex-snapshot
Gene Expression Profiling Specifies Chemokine, Mitochondrial and Lipid Metabolism Signatures in Leprosy
inferredcites →https://doi.org/10.1371/journal.ppat.1000683openalex-snapshot
The T3SS Effector EspT Defines a New Category of Invasive Enteropathogenic E. coli (EPEC) Which Form Intracellular Actin Pedestals
inferredcites →https://doi.org/10.1371/journal.ppat.1006325openalex-snapshot
T6SS: The bacterial "fight club" in the host gut
inferredcites →https://doi.org/10.32614/r.manualsopenalex-snapshot
R: A Language and Environment for Statistical Computing
inferredcites →https://doi.org/10.3389/fcimb.2016.00016openalex-snapshot
How Shigella Utilizes Ca2+ Jagged Edge Signals during Invasion of Epithelial Cells
inferredcites →https://doi.org/10.3389/fcimb.2016.00017openalex-snapshot
Interactions between Shigella flexneri and the Autophagy Machinery
inferredcites →https://doi.org/10.3389/fcimb.2016.00024openalex-snapshot
A Novel Small RNA Regulates Tolerance and Virulence in Shigella flexneri by Responding to Acidic Environmental Changes
inferredcites →https://doi.org/10.3389/fcimb.2016.00038openalex-snapshot
Cellular Aspects of Shigella Pathogenesis: Focus on the Manipulation of Host Cell Processes
inferredcites →https://doi.org/10.3389/fcimb.2016.00045openalex-snapshot
Shigella Diversity and Changing Landscape: Insights for the Twenty-First Century
inferredcites →https://doi.org/10.3389/fcimb.2017.00064openalex-snapshot
How Do the Virulence Factors of Shigella Work Together to Cause Disease?
inferredcites →https://doi.org/10.3389/fimmu.2015.00001openalex-snapshot
Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions
inferredcites →https://doi.org/10.3389/fimmu.2015.00219openalex-snapshot
Shigella Manipulates Host Immune Responses by Delivering Effector Proteins with Specific Roles
inferredcites →https://doi.org/10.4161/gmic.19325openalex-snapshot
Shigella
inferredcites →https://doi.org/10.4161/viru.1.1.10486openalex-snapshot
Reinforcement of epithelial cell adhesion to basement membrane by a bacterial pathogen as a new infectious stratagem

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Mechanism of membrane damage to Shigella sonnei by linalool from plant essential oils: A driver of oxidative stress
inferred← citeshttps://doi.org/10.1016/j.meegid.2021.105004openalex-snapshot
Therapeutic target identification via differential genome analysis of antibiotic resistant Shigella sonnei and inhibitor evaluation against a selected drug target
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