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Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatment
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/9781118468791.ch4openalex-snapshot
Somatic Genome Alterations in Human Lung Cancers
inferredcites →https://doi.org/10.1002/path.4230openalex-snapshot
Distinct evolutionary trajectories of primary high‐grade serous ovarian cancers revealed through spatial mutational profiling
inferredcites →https://doi.org/10.1007/978-1-4471-3020-8_7openalex-snapshot
Past, Present and the Future
inferredcites →https://doi.org/10.1016/j.cell.2012.04.023openalex-snapshot
The Life History of 21 Breast Cancers
inferredcites →https://doi.org/10.1016/j.cell.2013.01.019openalex-snapshot
Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
inferredcites →https://doi.org/10.1016/j.cell.2014.02.031openalex-snapshot
Genetic and Clonal Dissection of Murine Small Cell Lung Carcinoma Progression by Genome Sequencing
inferredcites →https://doi.org/10.1016/j.cell.2017.01.018openalex-snapshot
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
inferredcites →https://doi.org/10.1016/j.cell.2018.02.020openalex-snapshot
Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal
inferredcites →https://doi.org/10.1016/j.cell.2018.03.043openalex-snapshot
Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal
inferredcites →https://doi.org/10.1016/j.cell.2018.03.057openalex-snapshot
Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal
inferredcites →https://doi.org/10.1016/j.cell.2018.10.038openalex-snapshot
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
inferredcites →https://doi.org/10.1038/leu.2013.248openalex-snapshot
Clonal evolution in hematological malignancies and therapeutic implications
inferredcites →https://doi.org/10.1038/nature05945openalex-snapshot
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
inferredcites →https://doi.org/10.1038/nature12213openalex-snapshot
Mutational heterogeneity in cancer and the search for new cancer-associated genes
inferredcites →https://doi.org/10.1038/nature13385openalex-snapshot
Comprehensive molecular profiling of lung adenocarcinoma
inferredcites →https://doi.org/10.1038/nature19823openalex-snapshot
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
inferredcites →https://doi.org/10.1038/nature22364openalex-snapshot
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
inferredcites →https://doi.org/10.1038/nbt.2203openalex-snapshot
Absolute quantification of somatic DNA alterations in human cancer
inferredcites →https://doi.org/10.1038/ncomms11589openalex-snapshot
Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition
inferredcites →https://doi.org/10.1038/ng.3343openalex-snapshot
Paired exome analysis of Barrett's esophagus and adenocarcinoma
inferredcites →https://doi.org/10.1038/ng.3557openalex-snapshot
Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors
inferredcites →https://doi.org/10.1038/ng.3564openalex-snapshot
Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas
inferredcites →https://doi.org/10.1038/nm.3984openalex-snapshot
Pan-cancer analysis of the extent and consequences of intratumor heterogeneity
inferredcites →https://doi.org/10.1038/nmeth.2883openalex-snapshot
PyClone: statistical inference of clonal population structure in cancer
inferredcites →https://doi.org/10.1038/nrc1165openalex-snapshot
The significance of unstable chromosomes in colorectal cancer
inferredcites →https://doi.org/10.1038/nrclinonc.2017.166openalex-snapshot
Tumour heterogeneity and resistance to cancer therapies
inferredcites →https://doi.org/10.1038/s41556-018-0236-7openalex-snapshot
Tumour heterogeneity and metastasis at single-cell resolution
inferredcites →https://doi.org/10.1038/s41586-018-0792-9openalex-snapshot
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
inferredcites →https://doi.org/10.1038/s41698-017-0035-9openalex-snapshot
Resolving the phylogenetic origin of glioblastoma via multifocal genomic analysis of pre-treatment and treatment-resistant autopsy specimens
inferredcites →https://doi.org/10.1056/nejmoa1113205openalex-snapshot
Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
inferredcites →https://doi.org/10.1056/nejmoa1508887openalex-snapshot
Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F
inferredcites →https://doi.org/10.1056/nejmoa1616288openalex-snapshot
Tracking the Evolution of Non–Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1073/pnas.1009843107openalex-snapshot
Allele-specific copy number analysis of tumors
inferredcites →https://doi.org/10.1080/01621459.1995.10476550openalex-snapshot
Bayesian Density Estimation and Inference Using Mixtures
inferredcites →https://doi.org/10.1093/bioinformatics/btt546openalex-snapshot
Methods and challenges in timing chromosomal abnormalities within cancer samples
inferredcites →https://doi.org/10.1097/cco.0000000000000494openalex-snapshot
Treatment of anaplastic lymphoma kinase-positive non-small cell lung cancer: update and perspectives
inferredcites →https://doi.org/10.1101/161562openalex-snapshot
The evolutionary history of 2,658 cancers
inferredcites →https://doi.org/10.1101/312041openalex-snapshot
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
inferredcites →https://doi.org/10.1101/322859openalex-snapshot
The Repertoire of Mutational Signatures in Human Cancer
inferredcites →https://doi.org/10.1101/cshperspect.a026542openalex-snapshot
Evolution of Premalignant Disease
inferredcites →https://doi.org/10.1126/scitranslmed.3003316openalex-snapshot
Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers
inferredcites →https://doi.org/10.1142/9789814644730_0044openalex-snapshot
BAYCLONE: BAYESIAN NONPARAMETRIC INFERENCE OF TUMOR SUBCLONES USING NGS DATA
inferredcites →https://doi.org/10.1158/0008-5472.can-17-1229openalex-snapshot
Modeling the Subclonal Evolution of Cancer Cell Populations
inferredcites →https://doi.org/10.1158/1078-0432.ccr-11-2906openalex-snapshot
Mechanisms of Resistance to Crizotinib in Patients with ALK Gene Rearranged Non–Small Cell Lung Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-16-2540openalex-snapshot
Detecting the Presence and Progression of Premalignant Lung Lesions via Airway Gene Expression
inferredcites →https://doi.org/10.1158/2159-8290.cd-11-0028openalex-snapshot
Temporal Dissection of Tumorigenesis in Primary Cancers
inferredcites →https://doi.org/10.1158/2159-8290.cd-15-0369openalex-snapshot
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
inferredcites →https://doi.org/10.1158/2159-8290.cd-16-0596openalex-snapshot
Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK -Rearranged Lung Cancer
inferredcites →https://doi.org/10.1182/blood-2013-08-518886openalex-snapshot
Clinical and biological implications of driver mutations in myelodysplastic syndromes
inferredcites →https://doi.org/10.1186/1471-2105-15-35openalex-snapshot
Inferring clonal evolution of tumors from single nucleotide somatic mutations
inferredcites →https://doi.org/10.1186/s13059-015-0602-8openalex-snapshot
PhyloWGS: Reconstructing subclonal composition and evolution from whole-genome sequencing of tumors
inferredcites →https://doi.org/10.1200/jco.2009.22.6993openalex-snapshot
Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK
inferredcites →https://doi.org/10.1200/jco.2012.45.2029openalex-snapshot
Emerging Paradigms in the Development of Resistance to Tyrosine Kinase Inhibitors in Lung Cancer
inferredcites →https://doi.org/10.1371/journal.pcbi.1003665openalex-snapshot
SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/978-1-0716-3291-8_6openalex-snapshot
Reconstructing Phylogenetic Relationship in Bladder Cancer: A Methodological Overview
inferred← citeshttps://doi.org/10.1016/j.ccell.2019.08.005openalex-snapshot
Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
inferred← citeshttps://doi.org/10.1016/j.cell.2020.11.041openalex-snapshot
Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.cell.2021.03.009openalex-snapshot
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
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Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer
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Cancer phylogenetic inference using copy number alterations detected from DNA sequencing data
inferred← citeshttps://doi.org/10.1016/j.medj.2026.101266openalex-snapshot
Melanoma to rhabdomyosarcoma plasticity in the setting of immunotherapy
inferred← citeshttps://doi.org/10.1016/j.modpat.2025.100777openalex-snapshot
ELOC-Mutated Renal Cell Carcinoma is a Rare Indolent Tumor With Distinctive Genomic Characteristics
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AnnoMate: Exploring and annotating integrated molecular data through custom interactive visualizations
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Somatic mutations that affect early genetic progression and immune microenvironment in gastric carcinoma
inferred← citeshttps://doi.org/10.1016/j.semcancer.2023.04.002openalex-snapshot
Clonal interactions in cancer: Integrating quantitative models with experimental and clinical data
inferred← citeshttps://doi.org/10.1016/j.xcrm.2021.100500openalex-snapshot
Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma
inferred← citeshttps://doi.org/10.1016/j.xcrm.2025.102029openalex-snapshot
A patient-derived T cell lymphoma biorepository uncovers pathogenetic mechanisms and host-related therapeutic vulnerabilities
inferred← citeshttps://doi.org/10.1016/j.xgen.2022.100169openalex-snapshot
A patient-driven clinicogenomic partnership for metastatic prostate cancer
inferred← citeshttps://doi.org/10.1016/j.xgen.2025.100987openalex-snapshot
Detection of heterogeneous resistance mechanisms to tyrosine kinase inhibitors from cell-free DNA
inferred← citeshttps://doi.org/10.1038/s41467-021-24992-yopenalex-snapshot
CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data
inferred← citeshttps://doi.org/10.1038/s41467-022-30003-5openalex-snapshot
Alterations in homologous recombination repair genes in prostate cancer brain metastases
inferred← citeshttps://doi.org/10.1038/s41467-024-45835-6openalex-snapshot
Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial
inferred← citeshttps://doi.org/10.1038/s41523-021-00287-9openalex-snapshot
Nivolumab in combination with cabozantinib for metastatic triple-negative breast cancer: a phase II and biomarker study
inferred← citeshttps://doi.org/10.1038/s41571-021-00593-yopenalex-snapshot
Single-cell profiling of tumour evolution in multiple myeloma — opportunities for precision medicine
inferred← citeshttps://doi.org/10.1038/s41576-020-0265-5openalex-snapshot
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics
inferred← citeshttps://doi.org/10.1038/s41586-019-1252-xopenalex-snapshot
Growth dynamics in naturally progressing chronic lymphocytic leukaemia
inferred← citeshttps://doi.org/10.1038/s41586-024-07769-3openalex-snapshot
Prognostic genome and transcriptome signatures in colorectal cancers
inferred← citeshttps://doi.org/10.1038/s41586-025-09812-3openalex-snapshot
Whole-genome landscapes of 1,364 breast cancers
inferred← citeshttps://doi.org/10.1038/s41587-024-02250-yopenalex-snapshot
Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction
inferred← citeshttps://doi.org/10.1038/s41588-022-01140-wopenalex-snapshot
Molecular map of chronic lymphocytic leukemia and its impact on outcome
inferred← citeshttps://doi.org/10.1038/s41588-023-01355-5openalex-snapshot
Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer
inferred← citeshttps://doi.org/10.1038/s41588-023-01592-8openalex-snapshot
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance
inferred← citeshttps://doi.org/10.1038/s41588-025-02196-0openalex-snapshot
Genomic landscape of multiple myeloma and its precursor conditions
inferred← citeshttps://doi.org/10.1038/s41591-019-0561-9openalex-snapshot
Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers
inferred← citeshttps://doi.org/10.1038/s41591-021-01331-8openalex-snapshot
Evolution of delayed resistance to immunotherapy in a melanoma responder
inferred← citeshttps://doi.org/10.1038/s41591-022-02113-6openalex-snapshot
Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome
inferred← citeshttps://doi.org/10.1038/s41591-024-03240-yopenalex-snapshot
Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab
inferred← citeshttps://doi.org/10.1038/s41596-024-00962-8openalex-snapshot
Reconstructing phylogenetic trees from genome-wide somatic mutations in clonal samples
inferred← citeshttps://doi.org/10.1038/s41698-023-00466-wopenalex-snapshot
Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer
inferred← citeshttps://doi.org/10.1038/s43018-023-00533-yopenalex-snapshot
Inferring early genetic progression in cancers with unobtainable premalignant disease
inferred← citeshttps://doi.org/10.1038/s43018-025-01068-0openalex-snapshot
Tumor ecosystem and microbiome features associated with efficacy and resistance to avelumab plus chemoradiotherapy in head and neck cancer
inferred← citeshttps://doi.org/10.1093/bib/bbaf362openalex-snapshot
IMOP-Cancer: identifying mutation order pairs impacting cancer phenotypes
inferred← citeshttps://doi.org/10.1093/neuonc/noac220openalex-snapshot
Integrated longitudinal analysis of adult grade 4 diffuse gliomas with long-term relapse interval revealed upregulation of TGF-β signaling in recurrent tumors
inferred← citeshttps://doi.org/10.1101/2020.05.12.092296openalex-snapshot
The Genomic Landscape of Prostate Cancer Brain Metastases
inferred← citeshttps://doi.org/10.1101/2020.11.18.387837openalex-snapshot
Inferring parameters of cancer evolution from sequencing and clinical data
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A patient-driven clinicogenomic partnership through the Metastatic Prostate Cancer Project
inferred← citeshttps://doi.org/10.1101/2022.03.21.485199openalex-snapshot
Integrative Analysis of Checkpoint Blockade Response in Advanced Non-Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.1101/2022.06.14.495937openalex-snapshot
Crowd-sourced benchmarking of single-sample tumour subclonal reconstruction
inferred← citeshttps://doi.org/10.1101/2022.07.11.22277416openalex-snapshot
Genomic and Transcriptomic Determinants of Resistance to CDK4/6 Inhibitors and Response to Combined Exemestane plus Everolimus and Palbociclib in Patients with Metastatic Hormone Receptor Positive Breast Cancer
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The Metastatic Breast Cancer Project: leveraging patient-partnered research to expand the clinical and genomic landscape of metastatic breast cancer and accelerate discoveries
inferred← citeshttps://doi.org/10.1101/2024.07.03.601939openalex-snapshot
Subclonal mutation load predicts survival and response to immunotherapy in cancers with low to moderate tumor mutation burden
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U2AF1 S34F enhances tumorigenic potential of lung cells by exhibiting synergy with KRAS mutation and altering response to environmental stress
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Leveraging a Patient-Derived Tumoroid Platform for Precision Radiotherapy: Uncovering DNA Damage Repair Inhibitor-Mediated Radiosensitization and Therapeutic Resistance in Rectal Cancer
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CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data
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IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutation
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Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect
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Data from Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor–Positive Breast Cancer
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Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor–Positive Breast Cancer
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Supplementary Figures and Tables from MinimuMM-seq: Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma Pathology
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Supplementary Figures and Tables from MinimuMM-seq: Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma Pathology
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Supplementary Figures and Tables from MinimuMM-seq: Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma Pathology
inferred← citeshttps://doi.org/10.1158/2159-8290.24525047.v1openalex-snapshot
Supplementary Figures and Tables from MinimuMM-seq: Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma Pathology
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Data from Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer
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Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer
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MinimuMM-seq: Genome Sequencing of Circulating Tumor Cells for Minimally Invasive Molecular Characterization of Multiple Myeloma Pathology
inferred← citeshttps://doi.org/10.1158/2643-3230.bcd-20-0224openalex-snapshot
ZBTB33 Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing
inferred← citeshttps://doi.org/10.1172/jci153283openalex-snapshot
Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma
inferred← citeshttps://doi.org/10.1182/blood.2020006765openalex-snapshot
Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia
inferred← citeshttps://doi.org/10.1182/blood.2022016600openalex-snapshot
Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples
inferred← citeshttps://doi.org/10.1182/bloodadvances.2021004992openalex-snapshot
Clonal phylogeny and evolution of critical cytogenetic aberrations in multiple myeloma at single-cell level by QM-FISH
inferred← citeshttps://doi.org/10.1182/bloodadvances.2022008447openalex-snapshot
Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance
inferred← citeshttps://doi.org/10.1182/bloodadvances.2022009061openalex-snapshot
Genomics of PDGFR-rearranged hypereosinophilic syndrome
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A common methodological phylogenomics framework for intra-patient heteroplasmies to infer SARS-CoV-2 sublineages and tumor clones
inferred← citeshttps://doi.org/10.1186/s12967-024-04968-4openalex-snapshot
Genomic and transcriptomic profiling of combined small-cell lung cancer through microdissection: unveiling the transformational pathway of mixed subtype
inferred← citeshttps://doi.org/10.1186/s13059-026-03971-wopenalex-snapshot
Haplotype-aware segmentation with HapASeg increases accuracy of detecting homolog-specific somatic copy number alterations
inferred← citeshttps://doi.org/10.1200/po.22.00183openalex-snapshot
Mutational Footprint of Platinum Chemotherapy in a Secondary Thyroid Cancer
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1010677openalex-snapshot
Inferring parameters of cancer evolution in chronic lymphocytic leukemia
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3675752/v1openalex-snapshot
Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4270758/v1openalex-snapshot
Genomic mechanisms of resistance to tyrosine kinase inhibitors in HER2 amplified breast cancer
inferred← citeshttps://doi.org/10.3390/cancers13051148openalex-snapshot
Cutaneous Squamous Cell Carcinoma in the Age of Immunotherapy
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Genomic analysis of BCG unresponsive non-muscle-invasive bladder cancer identifies drivers of sensitivity to intravesical Gemcitabine/Docetaxel
inferred← citeshttps://doi.org/10.70675/302fb443z8270z4f6ezbbf7z20e95637a756openalex-snapshot
Statistical methods for deciphering intra-tumor hereterogeneity : challenges and opportunities for cancer clinical management
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