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Spontaneous retrotranspositions in normal tissues are rare and associated with cell-type-specific differentiation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/mrd.20423openalex-snapshot
Expression of LINE-1 retroposons is essential for murine preimplantation development
inferredcites →https://doi.org/10.1007/s12035-017-0421-xopenalex-snapshot
Overexpression of LINE-1 Retrotransposons in Autism Brain
inferredcites →https://doi.org/10.1016/0092-8674(85)90197-7openalex-snapshot
Ty elements transpose through an RNA intermediate
inferredcites →https://doi.org/10.1016/j.cell.2006.02.043openalex-snapshot
Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2010.05.021openalex-snapshot
LINE-1 Retrotransposition Activity in Human Genomes
inferredcites →https://doi.org/10.1016/j.cell.2011.08.016openalex-snapshot
Sperm Methylation Profiles Reveal Features of Epigenetic Inheritance and Evolution in Primates
inferredcites →https://doi.org/10.1016/j.cell.2012.09.035openalex-snapshot
Single-Neuron Sequencing Analysis of L1 Retrotransposition and Somatic Mutation in the Human Brain
inferredcites →https://doi.org/10.1016/j.cell.2015.03.026openalex-snapshot
Ubiquitous L1 Mosaicism in Hippocampal Neurons
inferredcites →https://doi.org/10.1016/j.celrep.2018.05.004openalex-snapshot
Tau Activates Transposable Elements in Alzheimer’s Disease
inferredcites →https://doi.org/10.1016/j.mrfmmm.2011.10.001openalex-snapshot
Direct mutation analysis by high-throughput sequencing: From germline to low-abundant, somatic variants
inferredcites →https://doi.org/10.1038/35057062openalex-snapshot
Initial sequencing and analysis of the human genome
inferredcites →https://doi.org/10.1038/nature09784openalex-snapshot
The Polycomb complex PRC2 and its mark in life
inferredcites →https://doi.org/10.1038/nature11245openalex-snapshot
Architecture of the human regulatory network derived from ENCODE data
inferredcites →https://doi.org/10.1038/ng.3945openalex-snapshot
LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo
inferredcites →https://doi.org/10.1038/ng0597-37openalex-snapshot
Many human L1 elements are capable of retrotransposition
inferredcites →https://doi.org/10.1038/ng1297-431openalex-snapshot
Rapid accumulation of genome rearrangements in liver but not in brain of old mice
inferredcites →https://doi.org/10.1038/nmeth.4227openalex-snapshot
Accurate identification of single-nucleotide variants in whole-genome-amplified single cells
inferredcites →https://doi.org/10.1038/nrg2072openalex-snapshot
Transposable elements and the epigenetic regulation of the genome
inferredcites →https://doi.org/10.1073/pnas.0831042100openalex-snapshot
Hot L1s account for the bulk of retrotransposition in the human population
inferredcites →https://doi.org/10.1073/pnas.1804046115openalex-snapshot
Longevity and transposon defense, the case of termite reproductives
inferredcites →https://doi.org/10.1073/pnas.97.15.8403openalex-snapshot
Distinct spectra of somatic mutations accumulated with age in mouse heart and small intestine
inferredcites →https://doi.org/10.1101/179705openalex-snapshot
Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours
inferredcites →https://doi.org/10.1111/acel.12047openalex-snapshot
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
inferredcites →https://doi.org/10.1111/acel.12465openalex-snapshot
Age‐associated de‐repression of retrotransposons in the Drosophila fat body, its potential cause and consequence
inferredcites →https://doi.org/10.1126/science.1222077openalex-snapshot
Landscape of Somatic Retrotransposition in Human Cancers
inferredcites →https://doi.org/10.1126/science.1251343openalex-snapshot
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes
inferredcites →https://doi.org/10.1126/science.aab1785openalex-snapshot
Somatic mutation in single human neurons tracks developmental and transcriptional history
inferredcites →https://doi.org/10.1126/science.aak9787openalex-snapshot
Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)
inferredcites →https://doi.org/10.1146/annurev-genet-120417-031501openalex-snapshot
Somatic Mutagenesis in Mammals and Its Implications for Human Disease and Aging
inferredcites →https://doi.org/10.1186/s13100-018-0128-1openalex-snapshot
L1 retrotransposition in the soma: a field jumping ahead
inferredcites →https://doi.org/10.1371/journal.pgen.1006385openalex-snapshot
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts
inferredcites →https://doi.org/10.18632/aging.100621openalex-snapshot
Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues
inferredcites →https://doi.org/10.7554/elife.12966openalex-snapshot
Resolving rates of mutation in the brain using single-neuron genomics
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